ライフサイエンスコーパス: molting

1 g pads without affecting isometric growth or molting.

2 clear hormone receptors essential for larval molting.

3 terial found between the two cuticles during molting.

4 erized by defects in pharyngeal function and molting.

5 proteins that have an essential role during molting.

6 rrounding syncytia and pronounced defects in molting.

7 nd functional maturation of their ORNs after molting.

8 tions of molting animals, oxygen binding and molting.

9 from moths that is expressed coincident with molting.

10 near the end of juvenile instars, and during molting.

11 hypoxia leads to growth and ecdysone-induced molting.

12 o the surrounding matrices and fluids during molting.

13 ynthesis, imaginal cell size, and control of molting.

14 enesis, early larval development, and larval molting.

15 egradative and biosynthetic process known as molting.

16 on hormone (EH), a neuropeptide regulator of molting.

17 ng the lethargus period that precedes larval molting.

18 Molting after the normal first instar period was restore

19 rdinated movement, adult sterility, abnormal molting and aberrant collagen deposition.

20 abnormal epidermal cell function, including molting and body size regulation, suggesting that CHR3 i

21 al ecdysteroid agonists for EcR that disrupt molting and can be used as safe pesticides.

22 he importance of FTZ-F1 nuclear receptors in molting and developmental control across evolutionarily

23 Molting and ecdysis in vitro required entry of the paras

24 In premolt, a preparation stage for upcoming molting and energy consumption, highly expressed genes w

25 n mutant background partially rescues larval molting and growth.

26 nctional maturation is not synchronized with molting and may not be completed until many weeks after

27 acle (USP) heterodimer is a key regulator in molting and metamorphoric processes, activating and repr

28 the steroid hormone ecdysone trigger larval molting and metamorphosis and coordinate aspects of embr

29 We studied the regulation of molting and metamorphosis in bed bugs with a goal to ide

30 Ecdysteroids initiate molting and metamorphosis in insects via a heterodimeric

31 e orthologs of NR genes that function during molting and metamorphosis in insects.

32 orms of the ecdysone receptor (EcR) initiate molting and metamorphosis of insects.

33 expression of genes known to be involved in molting and metamorphosis showed high levels of Kruppel

34 ing developmental transitions such as larval molting and metamorphosis through its active metabolite

35 (HaCHI) gene, critically required for insect molting and metamorphosis was selected as a potential ta

36 ne receptor gene generated defects in larval molting and metamorphosis, resulting in animals that fai

37 developmental events in arthropods including molting and metamorphosis.

38 ese polyhydroxylated sterols is critical for molting and metamorphosis.

39 ecdysone-regulated events during Drosophila molting and metamorphosis.

40 B/ATF proteins in essential functions during molting and metamorphosis.

41 bryonic developmental transitions, including molting and metamorphosis.

42 land coordinates and triggers events such as molting and metamorphosis.

43 n of insects from microbial infection during molting and metamorphosis.

44 ing developmental transitions such as larval molting and metamorphosis.

45 ecdysone, a steroid hormone that stimulates molting and metamorphosis.

46 s several developmental processes, including molting and morphogenesis, and results in larval lethali

47 tants display defects associated with larval molting and pupariation.

48 pmental transitions in Drosophila, including molting and puparium formation.

49 T-7), that is responsible for proper cuticle molting and re-synthesis.

50 These studies suggest that molting and successful development of L4 depends on the

51 vity was capable of affecting O. volvulus L3 molting and that the presence of both activities in a si

52 This positive system that promotes molting and the negative control via the critical weight

53 ontrols growth, and at high levels it causes molting and tissue differentiation.

54 roteins, and a significant reduction in both molting and viability of third-stage larvae.

55 variables and the sequence of blood feeding, molting, and aging.

56 bon is required for male viability, molting, and numerous events in metamorphosis including

57 ar receptor cofactor required for viability, molting, and numerous morphological events.

58 g acquired by ticks, persisting through tick molting, and reinfecting new mammalian hosts.

59 these ticks did not retain spirochetes upon molting, and subsequent B. burgdorferi transmission by a

60 cally expressed nuclear hormone receptors in molting, and to analyze meiosis-specific roles for prote

61 hophora + Tardigrada + Arthropoda) and other molting animals (Ecdysozoa), we analyzed the transcripto

62 oins nematodes with arthropods in a clade of molting animals, Ecdysozoa.

63 ns-may participate in two vital functions of molting animals, oxygen binding and molting.

64 stigate evolutionary relationships among all molting animals.

65 EcR-B mutant animals show defects in larval molting, arresting at the boundaries between the three l

66 let-7 express genes characteristic of larval molting as they initiate a supernumerary molt.

67 We show that low oxygen tension induces molting at smaller body size, consistent with the hypoth

68 RNA genes mir-48 and mir-84 exhibit retarded molting behavior and retarded adult gene expression in t

69 calize with peptide hormones known to elicit molting behavior, suggesting the involvement of novel re

70 survival rate was observed, together with a molting block, These findings confirm the important regu

71 The thatch is not discarded at molting but is enlarged by addition of strands as the la

72 v-SPI proteins play a vital role in nematode molting by controlling the activity of an endogenous ser

73 in the target cells and often--because of a molting checkpoint--arrests development globally.

74 mplete the larval molts but fail to exit the molting cycle at the adult stage.

75 mir-84 and let-7 promote exit from the molting cycle by regulating targets in the heterochronic

76 We propose that the molting cycle of C. elegans involves the dynamic assembl

77 During each molting cycle of insect development, synthesis of new cu

78 The molting cycle of nematodes involves the periodic synthes

79 To complete each molting cycle, insects display a stereotyped sequence of

80 fic changes in Cas-PMCA abundance during the molting cycle, with peak expression occurring during pre

81 inal neurohormone released at the end of the molting cycle.

82 elopment in neuronal cells that regulate the molting cycle.

83 abolism and physiological responses during a molting cycle.

84 . elegans development, in synchrony with the molting cycle.

85 e distinct but interconnected aspects of the molting cycle.

86 that LIN-42A and affiliated factors regulate molting cycles in much the same way that PER-based oscil

87 C. elegans molting cycles involve rhythmic cellular and animal beha

88 occurs relative to the approximately 6-hour molting cycles of postembryonic development.

89 fluctuate in a reiterated pattern during the molting cycles, reminiscent of the expression hierarchy

90 e molting program including the cessation of molting cycles.

91 The molting defect induced by Ce-imp-2 deficiency was mimick

92 t abnormalities, appeared independent of the molting defect.

93 s eliminated in larvae carrying mutations in molting defective (mld), a gene encoding a nuclear zinc

94 Comparison to molting-defective lrp-1(ku156) mutants revealed that the

95 ans, which emerged from a genetic screen for molting-defective mutants sensitized by low cholesterol.

96 l arrest, abnormal reproductive development, molting defects and increased adult longevity.

97 n apl-1(yn5) background caused lethality and molting defects at all larval stages, suggesting that ap

98 n chitinase-dependent loss of chitin, severe molting defects, and lethality at all developmental stag

99 y others in screens for genes causing larval molting defects, is identified here as a novel P-granule

100 ll differentiation contributes to peb-1(cu9) molting defects.

101 ed mutant phenotypes such as burst vulva and molting defects.

102 lopmental delays, developmental arrests, and molting defects.

103 rig mutants display defects in molting, delayed larval development, larval lethality, d

104 tive action of chitinases and possibly other molting enzymes.

105 The molting fluid enzyme chitinase, which degrades the matri

106 t to serve as a physical barrier, preventing molting fluid enzymes from accessing the new cuticle and

107 ection of the newly synthesized cuticle from molting fluid enzymes has long been attributed to the pr

108 A decrease in the percentage of larvae molting from the third stage to the fourth stage was obs

109 In D. immitis, molting from the third to the fourth larval stage can be

110 mulates ecdysteroid production by crustacean molting glands (Y-organs).

111 uth of their core sub-Antarctic breeding and molting grounds.

112 they use sea ice as a breeding, foraging and molting habitat.

113 We show that interinstar molting has the same size-related oxygen-dependent mecha

114 ates sterol homeostasis and is essential for molting hormone (20-hydroxyecdysone; 20E) biosynthesis.

115 s of the ring gland that produce ecdysteroid molting hormone (EC).

116 cline in the circulating titer of the insect molting hormone 20-hydroxyecdysone (20-HE).

117 The steroid insect molting hormone 20-hydroxyecdysone is believed to contro

118 s degrees by feeding the mutants the steroid molting hormone 20-hydroxyecdysone, or the precursors of

119 teps in the conversion of cholesterol to the molting hormone 20-hydroxyecdysone.

120 ophila polytene chromosomes initiated by the molting hormone 20-hydroxyecdysone.

121 ecdysteroids, herbal analogues of the insect molting hormone and their semisynthetic derivatives, wer

122 lex that mediates the effects of the steroid molting hormone ecdysone by activating and repressing ex

123 with a molt, triggered by release of steroid molting hormone ecdysone from the prothoracic gland (PG)

124 , growth ceases in response to a peak of the molting hormone ecdysone that coincides with a nutrition

125 The molting hormone ecdysone triggers chromatin changes via

126 TTH), which stimulates the production of the molting hormone ecdysone via an incompletely defined sig

127 Because the PGs produce the molting hormone ecdysone, we hypothesized that ecdysone

128 of ecdysteroids that includes the principal molting hormone, 20-hydroxyecdysone (20E), and ecdysone

129 stage can be induced in vitro by the insect molting hormone, 20-hydroxyecdysone, suggesting that thi

130 functions as a receptor for the ecdysteroid molting hormones of insects.

131 racteristic concentration of the ecdysteroid molting hormones that regulate metamorphosis.

132 Synthesis of ecdysteroids (molting hormones) by crustacean Y-organs is regulated by

133 The prepupal peak of ecdysteroids (molting hormones) triggers the regression of APR dendrit

134 ation of the hypodermis and the cessation of molting in C. elegans.

135 olism and biological processes pertaining to molting in crustaceans.

136 ties have also been found to be critical for molting in O. volvulus L3 larvae.

137 ion level of chitinase 1 and caused abortive molting in the insects.

138 h the new and the old cuticles during larval molting, in particular in the regions that are degraded

139 PIXR abrogation also impairs larval molting, indicative of its role in tick biology.

140 ae were fed on EMLA-infected mice, and after molting, infected nymphs were used to infest naive anima

141 Molting is a critical developmental process for crustace

142 Molting is elicited by a critical titer of ecdysteroids

143 Crustacean molting is known to be regulated largely by ecdysteroids

144 Molting is required for progression between larval stage

145 Onchocerca volvulus third-stage larvae (L3), molting L3 (mL3), and crude extract from adult males (M-

146 nfective larval (third-stage larvae [L3] and molting L3 [mL3]), adult female worm (F-OvAg), and skin

147 Secondly, by immunoscreening the molting L3 cDNA library with a pool of human sera from p

148 fection, the third-stage larvae (L3) and the molting L3.

149 endogenous cysteine protease was detected in molting larvae after binding to labeled inhibitors, and

150 o Ov-spi transcripts are up-regulated in the molting larvae and adult stages of the development of th

151 he separation between the cuticles occurs in molting larvae.

152 y avoidance of octanol and quiescence during molting lethargus.

153 as arousal thresholds and quiescence during molting lethargus.

154 DA1877 affects cyclic gene expression during molting, likely through the nuclear hormone receptor NHR

155 jor aspects of insect development, including molting, metamorphosis, and reproduction.

156 n suggests that the function of CPZ-1 during molting might be conserved in other nematodes.

157 survival of third stage larvae (L3), and the molting of L3 to L4 in vitro.

158 osantel was found also to completely inhibit molting of O. volvulus infective L3 stage larvae.

159 Chitinases that function in the molting of the larval exoskeleton have been characterize

160 vae also show defects in tracheal growth and molting of their tracheal cuticle.

161 T5, was found to be required for pupal-adult molting only.

162 crust expression with gender, social status, molting or feeding, dominant animals show significantly

163 singly, PTTH production is not essential for molting or metamorphosis.

164 In both sexes, lep-2 mutants fail to cease molting or produce an adult cuticle.

165 The monophyly of Ecdysozoa, molting organisms, was not supported by any of the analy

166 mutant suggests that cpz-1 has a role in the molting pathways.

167 Alaska (1998-2010), sampled during breeding/molting periods.

168 p-2 leads to embryonic death and an abnormal molting phenotype in Caenorhabditis elegans.

169 We have identified a regulator of molting, pqn-47.

170 tor, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitte

171 ecdysone and/or ponasterone A initiates the molting process through binding to its conserved heterod

172 chitinase family genes, primarily during the molting process, and provide a biological rationale for

173 gest that pqn-47 executes key aspects of the molting program including the cessation of molting cycle

174 pation but was dispensable for larval-larval molting, pupation, and adult eclosion.

175 ytic domains, prevented embryo hatch, larval molting, pupation, and adult metamorphosis, indicating a

176 high as 9.5 pM during the M. angustirostris molting season.

177 anugo pups, Hg concentrates in the hair, and molting serves as a main detoxification route.

178 or: camouflage mismatch in seasonally colour molting species confronting decreasing snow cover durati

179 will be critical for hares and other colour molting species to keep up with climate change.

180 ified differentially expressed genes at four molting stages of Chinese mitten crab (Eriocheir sinensi

181 erentially expressed genes amongst different molting stages, provide novel insights into the function

182 s differentially expressed amongst different molting stages.

183 mice, and (iii) able to persist through tick molting stages.

184 ly control the production and release of the molting steroid ecdysone.

185 Our results demonstrate that the molting steroid hormone ecdysone in adult Drosophila is

186 Histological evidence of molting suggests that after summer had passed, molt bega

187 -1, was identified through the analysis of a molting third-stage larvae expressed sequence tag datase

188 e basal layer of the cuticle of third-stage, molting third-stage, and fourth-stage larvae, the body c

189 us, while loss of PAN-1 in the soma inhibits molting, this report demonstrates that PAN-1 is also a P

190 efficiently transmitted the ehrlichiae after molting to nymphs, thereby demonstrating vector competen

191 lus microplus ticks could acquire and, after molting to the adult stage, transmit B. equi to naive ho

192 PCR positive, after feeding on the sheep and molting to the next instar, increased marginally with in

193 This mechanism enables exoskeletal molting, tube expansion, and epithelial integrity.

194 Molting was completely inhibited in the presence of 50-2

195 its biological activities on O. volvulus L3 molting was investigated.

196 Consistent with a function in molting, we found that PEB-1 was detectable in all hypod

197 gland cells have prominent functions during molting, we suggest defective gland cell differentiation

198 ruitment, inhibits reproduction, and induces molting, with no change in plasma prolactin levels.

199 uctor-A causes severe defects during cuticle molting, wound protection, tube expansion and larval gro