ライフサイエンスコーパス: monkey

1 established in New World primates (squirrel monkeys).

2 451 ((18)F-T807) in mice, rats, and a rhesus monkey.

3 p codon (R22X) in the albino robust capuchin monkey.

4 but is significantly higher in mouse than in monkey.

5 ogical recordings in rVLPFC and FEF from one monkey.

6 cts were dependent on the social rank of the monkey.

7 hypertrophy and force production in mice and monkeys.

8 pattern reported after selective lesions in monkeys.

9 ates after a single passage in African green monkeys.

10 rotic, hypertensive monkeys to that in young monkeys.

11 hich at low doses improved working memory in monkeys.

12 cortex, in sufentanil-anaesthetized marmoset monkeys.

13 the perceptual performance of our amblyopic monkeys.

14 iscale imaging of synaptic markers in rhesus monkeys.

15 ased while sensitivity decreased in dominant monkeys.

16 ts activity-based sleep parameters in rhesus monkeys.

17 tamatergic signaling in chronically drinking monkeys.

18 ated to determine the effect of CR in rhesus monkeys.

19 e severity of perceptual loss for individual monkeys.

20 and central nucleus of the amygdala (CeA) in monkeys.

21 innervation of the CG in Macaca fascicularis monkeys.

22 n the sensorimotor cortex of awake, behaving monkeys.

23 n about preference for facial averageness in monkeys.

24 f their rate-decreasing effects in Old World monkeys.

25 t deviations from comparable data for normal monkeys.

26 ong-term two-photon imaging in awake macaque monkeys.

27 er administration of 1 to rodents, dogs, and monkeys.

28 decoded times and the timing behavior of the monkeys.

29 iscriminated between low- and heavy-drinking monkeys.

30 ined models of cocaine reward and relapse in monkeys.

31 mary visual cortex of awake behaving macaque monkeys.

32 owed by slight decline until adulthood in HD monkeys.

33 ation titers in RSV-preexposed African green monkeys.

34 o dissociate the effects of each rate in two monkeys.

35 ined, it functioned as a reinforcer in three monkeys.

36 a vaccine against DENV2 infection in rhesus monkeys.

37 he lateral prefrontal cortex (PFC) of rhesus monkeys.

38 endant changes in the tool sizes used by the monkeys.

39 rant drug self-administration in rodents and monkeys.

40 er for global motion direction in humans and monkeys.

41 rcement; THC functioned as reinforcer in two monkeys.

42 ontrast, and size) in V1 of two male macaque monkeys.

43 In monkeys, (18)F-LY2459989 was metabolized at a moderate r

44 bject data revealed that for the majority of monkeys (9/15), serving as an intruder in another social

45 Here, we explicitly test in marmoset monkeys-a very vocal and cooperatively breeding species

46 VS lesions caused a specific deficit in the monkeys' ability to discriminate between images with dif

47 nt, we examined the effects of VS lesions on monkeys' ability to learn that choosing a particular act

48 We examined the time course of young monkeys' activity with nuts before, during, and followin

49 bus detection was investigated in cynomolgus monkeys after insertion of a roughened catheter into eit

50 cognitive decline previously reported as HD monkeys aged.

51 African green monkeys (AGM) and sooty mangabeys (SM) are well-studied

52 African green monkeys (AGMs) are a natural host of SIV that do not dev

53 om chronically SIVagm-infected African green monkeys (AGMs) were frequently CXCR5(+) and entered and

54 [PTMs]) and nonpathogenic (in African green monkeys [AGMs]) SIVsab infections to assess the signific

55 One of these two monkeys also showed no anamnestic increases in antibody

56 ulus using a sparse noise stimulus while the monkeys alternated fixation.

57 single neurons in the cortex of the macaque monkey and using computational models from mathematical

58 responses of MSTd neurons in two male rhesus monkeys and by applying a recently-developed method to a

59 essful recovery of features corresponding to monkeys and faces in the image set.

60 FC, and ventral intraparietal area of rhesus monkeys and found that adjacent neurons represent marked

61 These data across monkeys and humans support a regulatory relationship bet

62 bserved in the intraparietal sulcus (IPS) in monkeys and humans, including children.

63 ing key features of cortical connectivity in monkeys and humans, specifically the presence of relativ

64 evelop in the same cortical locations across monkeys and humans, which raises the possibility of comm

65 th a modification of confocal AOSLO, in both monkeys and humans.

66 Indeed, previous experiments on squirrel monkeys and macaque monkeys showed that social isolation

67 d PSD95 proteins were higher in postpubertal monkeys and positively predicted activity-dependent PV l

68 that health benefits of CR are conserved in monkeys and suggest that CR mechanisms are likely transl

69 match between the reward amount given to the monkeys and the amount they expected: A lower-than-expec

70 tablish a link between the WM codes found in monkeys and those in humans and emphasize the importance

71 tant to TTX in distal peripheral branches of monkeys and WT and NaV1.9(-/-) mice.

72 human and nonhuman primates (common marmoset monkeys) and the feasibility of noninvasively imaging an

73 membranes of nucleated cells of rodent, dog, monkey, and human origin; increase ion permeability acro

74 uronal culture, in brain slices of mouse and monkey, and in mouse brain in vivo.

75 sible for the albinism in a captive capuchin monkey, and to describe the TYR gene of normal phenotype

76 from medial premotor cortex (MPC) in macaque monkeys, and computational modeling, to establish eviden

77 .g., non-primates, strepsirrhines, New World monkeys, and hominoids).

78 s to alcohol and cocaine intake across mice, monkeys, and humans.

79 nduces robust, lasting consequences in mice, monkeys, and humans.

80 nding perceptual decision making in rodents, monkeys, and humans.

81 ed CA3 subregion of the hippocampus in rats, monkeys, and humans.

82 Characterization of both mouse and monkey antiheroin antibodies by surface plasmon resonanc

83 Vervet monkeys are among the most widely distributed nonhuman p

84 In monkeys, assessment of safety and target cell depletion

85 We found that monkeys based their choices on evidence presented in ear

86 After monkeys became proficient in this task, we tested their

87 ory in which preferences are stochastic; the monkeys behaved "as if" they had well-structured prefere

88 severity of myelin deficit lesions in rhesus monkey brain induced by experimental autoimmune encephal

89 In the macaque monkey brain, posterior inferior temporal (PIT) cortex c

90 ed in vitro and had high specific binding in monkey brain.

91 verity of myelin deficit in mouse and rhesus monkey brains.

92 striking convergences with findings from the monkey, but also raised new questions and provided new t

93 more sensitive to endotoxin than are mice or monkeys, but any underlying differences in inflammatory

94 sed nicotine self-administration in rats and monkeys, but did not affect cocaine self-administration.

95 All of these effects of Ro 61-8048 in monkeys, but not in rats, were reversed by pretreatment

96 ng acoustic and CI signals in awake marmoset monkeys (Callithrix jacchus).

97 In lymph nodes of surviving monkeys, changes in [(18)F]-FDG uptake positively correl

98 ependent dopamine responses emerged prior to monkeys' choice initiation, raising the possibility that

99 or the OCA1 albino phenotype in the capuchin monkey, classified as Sapajus apella.

100 Here we show in a male rhesus monkey cohort (N = 60) that infant performance in a task

101 ent was significantly greater in subordinate monkeys compared with dominant animals.

102 verlap with regions previously identified in monkeys composed of bilateral premotor cortices, supplem

103 On each trial, monkeys could choose either a tap or a hold to earn the

104 We found that monkeys could generate predictive saccades synchronized

105 Thus, we showed that rhesus monkeys could learn to categorize on the basis of implie

106 ehaviour generalized to novel tempi, and the monkeys could maintain the tempo internally.

107 est that persistent EBOV infection in rhesus monkeys could serve as a model for persistent EBOV infec

108 We selected a high-affinity monkey cross-reactive anti-CLL-1 arm and tested several

109 type 1 virus were infected, and many of the monkeys developed paralysis.

110 emergence of face domains, but face-deprived monkeys did not, indicating that face looking is not inn

111 Here, in a Pavlovian procedure in which monkeys displayed a diverse repertoire of reward-related

112 Dominant and subordinate monkeys displayed distinctly different patterns of brain

113 Supporting this interpretation, in monkey DLPFC, higher minor-to-major variant ratios predi

114 Core monkey DMN and shift-selective regions shared several fu

115 er shifts in spatial attention activated the monkey DMN.

116 e amygdala and orbitofrontal cortex (OFC) of monkeys during a Pavlovian task in which the relative am

117 Td) and ventral intraparietal (VIP) areas of monkeys during perception of self-motion.

118 stibulo-spinal circuitry of behaving macaque monkeys during temporally precise activation of vestibul

119 e complimentary techniques of human fMRI and monkey electrophysiology in a context-dependent stop sig

120 Monkey electrophysiology revealed that the bimodal super

121 In drinking monkeys, evoked firing of OFC pyramidal neurons was redu

122 Twenty-two to 30-year-old rhesus monkeys exposed to 30% caloric restriction since 7-14 ye

123 rtical (MI) neurons of chronically amputated monkeys exposed to control a multiple-degree-of-freedom

124 When administered to rabbit and monkey eyes, the half-life of the modified proteins is i

125 During this time selective responsiveness to monkey faces emerges.

126 s in visual cortex of anesthetized amblyopic monkeys (female Macaca nemestrina), using 96-channel "Ut

127 nter-organelle contacts in live cells from a monkey fibroblast cell line.

128 Our results parallel previous monkey findings and show that the supplementary motor ar

129 Examination of eye movements revealed that monkeys fixated the illusory internal facial features in

130 ected PAMs and NAMs of mGluRs in rodents and monkeys, focusing on whether they reduce drug self-admin

131 ions can be achieved and maintained in awake monkeys for months.

132 rmacokinetic (PK) studies in mouse, rat, and monkey further confirmed the developability of this uniq

133 ated with different inducers; untreated male monkeys, guinea pigs, rabbits, and hamsters; and female

134 CE STATEMENT Working memory (WM) research in monkeys has identified a network of regions, including p

135 europhysiological and behavioral research in monkeys has offered a better understanding of how the pr

136 in the caudate nucleus and putamen, whereas monkeys have a more heterogeneous representation of mult

137 acking retinotopy, several recent studies in monkeys have shown that retinotopic maps extend to face

138 Transgenic Huntington's disease monkey (HD monkey) model provides great opportunity for

139 Cynomolgus monkey heterotopic cardiac allograft recipients were tre

140 C layer neurons did not match the quality of monkey images for several reasons, including safety conc

141 African green monkeys immunized with two doses of the vector expressin

142 We use this model together with human and monkey in vitro models simulating peri-gastrulation deve

143 binatorial approach using human, porcine and monkey in vivo and in vitro models provides synthetic in

144 associated with drusenoid lesions in rhesus monkeys in ARMS2 and HTRA1 were similar in frequency bet

145 icate that humans and great apes differ from monkeys in having a preponderance of multipolar ChAT-ir

146 ndard-deviation of the intervals produced by monkeys in SCT is replicated by the model.

147 ured to quantify LPA1 in the lungs of rhesus monkeys in vivo.

148 o decrease food-maintained responding in the monkeys in which CP 55 940 functioned as a reinforcer.

149 Compared to that for other monkeys, including red-capped mangabeys and closely rela

150 ked relative reward magnitude, implying that monkeys integrated information about recent rewards to a

151 ck MeV infections and syncytium formation in monkey kidney cell lines.

152 Cytotoxicity was evaluated in green monkey kidney epithelial (Vero) cells and MT-4 leukocyte

153 293T (embryonic kidney), Vero (African-green monkey kidney epithelial), 3T12 (mouse fibroblast), and

154 Monkeys learned to perform two different actions, "tap"

155 We studied bearded capuchin monkeys learning a traditional tool-using skill, crackin

156 Gaze tracking revealed that control monkeys looked preferentially at faces, even at ages pri

157 ficantly smaller in the mouse FC than in the monkey LPFC.

158 by SIVagmSab to infect sabaeus African green monkey lymphocytes.

159 a pseudo-random manual tracking task in the monkey (Macaca mulatta), climbing fiber discharge dynami

160 shown by four seminal, published studies in monkeys (Macaca mulatta) performing multialternative tas

161 e primary visual cortex (V1; N = 15) of male monkeys (Macaca mulatta).

162 ups in areas V1 and V2 of six female macaque monkeys (Macaca nemestrina) made amblyopic by artificial

163 ments and dorsal roots from mice and pigtail monkeys (Macaca nemestrina).

164 encoding of the instrumental responses that monkeys made on each trial.

165 ults show that the signals measured from the monkey medial posterior parietal cortex are valid for co

166 om neural data acquired from area V6A of the monkey medial posterior parietal cortex.

167 In rodents and rhesus monkeys, MK-8722-mediated AMPK activation in skeletal mu

168 A rhesus monkey model may lay the foundation to study EVD sequela

169 A monkey model of Zika virus (ZIKV) infection is urgently

170 Transgenic Huntington's disease monkey (HD monkey) model provides great opportunity for studying di

171 protein in the cotton rat and African green monkey models for their replication, immunogenicity, and

172 n the present study we used rat and squirrel monkey models of reward and relapse to examine the possi

173 group of cocaine-experienced male cynomolgus monkeys (N=4), THC SA was examined under a second-order

174 vity in a prefrontal sensorimotor area while monkeys naturally switched between exploring and exploit

175 ti-electrode array recordings from human and monkey neocortex by examining the spike-triggered LFP av

176 Thus, in human and monkey neocortex, the LFP reflects primarily inhibitory

177 re their specializations, we trained macaque monkeys on two tasks: one required updating representati

178 ngabeys, and SIVagmVer, which infects vervet monkeys, our data suggest a unifying model whereby in na

179 ngent vocal feedback to twin infant marmoset monkeys over their first 2 months of life, the interval

180 The emergence of human malaria due to the monkey parasite Plasmodium knowlesi threatens eliminatio

181 Here we record LPFC neuronal activity while monkeys perceive the motion direction of a stimulus that

182 ctive neurons in V1 and V2 while two macaque monkeys performed a fine orientation discrimination task

183 Monkeys performed a visual matching task that required t

184 microstimulation at different periods while monkeys performed instructed and choice eye movement tas

185 lectrical microstimulation of the dPul while monkeys performed saccade tasks toward instructed and fr

186 We show that dopamine responses in monkeys performing a perceptually ambiguous decision tas

187 e ventrolateral prefrontal cortex (vlPFC) of monkeys performing a shape discrimination task respond m

188 orded neurons from dorsal premotor cortex of monkeys performing a visual discrimination task with rea

189 of delay and fixation cells in the dlPFC of monkeys performing a working memory task.

190 in vitro against Daudi cells with cynomolgus monkey peripheral blood mononuclear cells, and had minim

191 Moreover, in the 13 treated monkeys, plasma virus loads subsequently declined to und

192 ependent monocyte phagocytosis of cynomolgus monkey platelets, and cynomolgus platelet activation in

193 g implicit and explicit forms of learning in monkey prefrontal networks.

194 om our own studies of both New and Old World monkeys, prosimian galagos, and close relatives of prima

195 r C-group motoneurons in Macaca fascicularis monkeys receive a direct cMRF input by injecting this po

196 sistently infected all the animals, and many monkeys receiving 10(8) or 10(9) TCID50 developed paraly

197 w that whereas P cynomolgi merozoites invade monkey red blood cells indiscriminately in vitro, in hum

198 during in vivo adaptation in mice and rhesus monkeys, rendering the cagT4SS nonfunctional; however, t

199 A seminal finding in monkey research is that neurons in the prefrontal cortex

200 ibratory frequencies in parallel to previous monkey research.

201 transcriptome profiling revealed that mutant monkeys resembled RTT patients in immune gene dysregulat

202 recently shown that macaques and wild vervet monkeys respond strongly to partially exposed snake mode

203 A small-animal PET scan of a rhesus monkey revealed moderate initial brain uptake (SUV, 1.9

204 e we investigated whether recombinant rhesus monkey rhadinovirus (RRV) could be used as a vaccine aga

205 of recombinant, replication-competent rhesus monkey rhadinovirus (RRV), a persisting herpesvirus.

206 eceptor (CBR) agonist CP 55 940 in Old World monkeys (rhesus and cynomolgus), a species that has been

207 a generic network simultaneously explains a monkey's learning curve and the evolution of qualitative

208 To investigate if squirrel monkeys (Saimiri sciureus), which are reported to develo

209 Adult male/female rhesus monkeys self-administered methamphetamine (0.03 mg/kg/in

210 For subordinate monkeys, sensitivity to the reinforcing effects of cocai

211 In cynomolgus monkeys, SGN-CD19B effectively depleted CD20(+) B lympho

212 Intact monkeys shifted their choice to whichever action produce

213 Whereas intact (control) monkeys shifted their choices toward the action associat

214 ated to SIVcpz and infect a subset of guenon monkeys show an epidemiology resembling that of SIVcpz.

215 s that ZIKV populations in mosquito-infected monkeys show greater sequence heterogeneity and lower ov

216 the vaccine phase, plasma of all vaccinated monkeys showed neutralizing activity against DENV2.

217 Two of four vaccinated monkeys showed no detectable viral RNA after subsequent

218 cinated controls, two of the four vaccinated monkeys showed no detectable viral RNA sequences in plas

219 experiments on squirrel monkeys and macaque monkeys showed that social isolation [2, 3], deafness [2

220 n activity or perturbing brain regions while monkeys simultaneously make behavioral judgements about

221 ogenic infection with SIV from African green monkeys (SIVagm), follicles remain generally virus free.

222 In monkeys, social status influences the reinforcing effect

223 A direct mapping between monkey studies and human research is still controversial

224 from preclinical vaccine studies in mice and monkeys suggest that an effective vaccine will likely be

225 Histological evidence from young rhesus monkeys suggests that HC development is characterized by

226 that are most plastic during ELS exposure in monkeys sustain the greatest change in gene expression,

227 When others stop cracking nuts, young monkeys sustain the uncommon actions of percussing and s

228 after oral administration in the cynomolgus monkey that showed a very low peak-to-trough ratio.

229 tralization antibody titers in African green monkeys that had been infected previously.

230 y responses in otherwise asymptomatic rhesus monkeys that had survived infection in the absence of or

231 freely moving, naturally behaving, marmoset monkeys that may facilitate natural primate conversation

232 C) and prefrontal (PFC) cortices in two male monkeys that performed spatial and motion direction-base

233 led preference theory, we measured in rhesus monkeys the frequency of repeated choices between bundle

234 r single dendritic spine resolution in awake monkeys, the techniques reported can help bridge the use

235 Here we report that in rhesus monkeys, there is independent selective pressure for los

236 In human adults and monkeys, this process involves the motor system, with a

237 the middle temporal (MT) area of the macaque monkey to study the neural mechanisms that underlie the

238 yl)cyclopropane-1-carboxylic acid) in rhesus monkeys to image LPA1 in the lung in vivo with PET.

239 discriminate these possibilities, we trained monkeys to make synchronized eye movements to a visual m

240 We trained monkeys to operate a brain-computer interface in both tw

241 To clarify this issue, we trained rhesus monkeys to perform a center-out task in which arm moveme

242 This study shows the feasibility of training monkeys to perform active judgements about certain aspec

243 ers' cracking nuts immediately prompts young monkeys to start handling and percussing nuts, and they

244 lusion in old, atherosclerotic, hypertensive monkeys to that in young monkeys.

245 of V1 neurons in alert and behaving macaque monkeys trained on an attention-demanding contrast-chang

246 al task-relevant sensory neurons can predict monkeys' trial-by-trial choices in perceptual decision-m

247 Eight monkeys underwent nonmyeloablative conditioning and majo

248 performance on both tasks in three groups of monkeys: unoperated controls and those with selective, f

249 Next, THC was administered daily to monkeys until tolerance developed to rate-decreasing eff

250 plasma of mice and in the plasma of a rhesus monkey using high-performance liquid chromatography.

251 ategories can be ordered serially by macaque monkeys using a behavioral paradigm that provides no exp

252 d this interaction, we tested 3 male macaque monkeys using both [(11)C]DASB and [(18)F]MPPF, two PET

253 n processing in the auditory cortex of awake monkeys using functional magnetic resonance imaging (fMR

254 to the significant differences seen between monkey V1 and LPFC.

255 population response impact sensory coding in monkey V1 and perceptual performance.

256 clusive: some argue mouse V1 is analogous to monkey V1; others argue that it displays complex motion

257 ciency virus type 1 (HIV-1) and Mason-Pfizer monkey virus (M-PMV) but not Moloney murine leukemia vir

258 ional enhancer element from the Mason-Pfizer monkey virus can override the silencing and promote tran

259 V-1, murine leukemia virus, and Mason-Pfizer monkey virus), two hepadnaviruses (hepatitis B virus and

260 In monkey visual area V1, nearby local populations driven b

261 Here, we show that populations of cells in monkey visual cortex exhibit rapid fluctuations in synch

262 Using multielectrodes in monkey visual cortex, we measured spike-count correlatio

263 With a biomechanical model of the marmoset monkey vocal apparatus and behavioral developmental data

264 r, these elements influence the shape of the monkeys' vocal developmental landscape, tilting, rotatin

265 On the test day, a dominant or subordinate monkey was removed from his homecage and placed into ano

266 Whole brain white matter integrity of HD-monkeys was examined longitudinally from 6 to 48 months

267 re associated with attention and gaze, while monkeys watched video of natural scenes.

268 In cynomolgus monkeys, we again observed a short half-life, but were a

269 tional magnetic resonance imaging in macaque monkeys, we discovered a network centered in the medial

270 From a pool of 109 peri-adolescent rhesus monkeys, we formed groups characterized by high or low l

271 postsynaptic sites in the amygdala in rhesus monkeys, we found that the anterior cingulate cortex inn

272 oss cortical depths in V1 and V2 of behaving monkeys, we identified spatiotemporally dissociable proc

273 Grafted monkeys were also challenged with levodopa but did not s

274 Male mutant monkeys were embryonic lethal, reiterating that RTT is a

275 an "artificial grammar") in which humans and monkeys were exposed to sequences of nonsense words with

276 e albino and five non-albino robust capuchin monkeys were identified as Sapajus apella, based on phyl

277 Sixteen rhesus monkeys were lethally infected with MARV or RAVV and tre

278 comparing bottom-up sensory inputs (what the monkeys were looking at) and top-down cognitive encoding

279 top-down cognitive encoding inputs (what the monkeys were looking for).

280 nd that, in stimulus-based RL, the VS lesion monkeys were more influenced by negative feedback and ha

281 forms of social interaction, whereas younger monkeys were more likely to innovate in other behavioral

282 Older, more social monkeys were more likely to invent new forms of social i

283 PET scans in rhesus monkeys were obtained on a small-animal scanner to asses

284 relapse-like behavior when abstinent rats or monkeys were reexposed to nicotine and/or cues that had

285 Toward this end, monkeys were rendered parkinsonian with n-methyl-4-pheny

286 e-induced LH surges in ovariectomized female monkeys were severely attenuated by systemic administrat

287 Two Macaca fascicularis monkeys were trained to perform an instructed-delay reac

288 mug/kg) functioned as a reinforcer in three monkeys, whereas THC (0.01-10 mug/kg) did not have reinf

289 ve efficacy in cotton rats and African green monkeys, which are among the best available animal model

290 imulation techniques in sedated female cebus monkeys while recording EMG signals from intrinsic hand

291 PGT121 protected 6 out of 7 monkeys, while 6 out of 7 3BNC117-pretreated animals bec

292 imaging with genetic tools in awake macaque monkeys will enable fundamental advances in our understa

293 We perform two studies in rhesus monkeys with Ad35/Ad26 vectors expressing SIVmac239 Gag/

294 A previous study revealed that, although monkeys with bilateral lesions of either the orbitofront

295 hever action produced the higher-value food; monkeys with crossed surgical disconnection of OFC and t

296 iated with the higher value (nonsated) food, monkeys with crossed surgical disconnection of the amygd

297 ation-resistant SIVsmE660 variants in rhesus monkeys with restrictive TRIM5alpha alleles.

298 ified Cas9 in one-cell embryos leads to live monkeys with the targeted gene modifications.

299 Marmoset monkeys with unilateral lesions of either the antOFC or

300 Compared with controls, monkeys with VS lesions had deficits in learning to sele