ライフサイエンスコーパス: monoamine oxidase A

1 e include potent and selective inhibitors of monoamine oxidase A.

2 ents and four Sp1-binding sites in the human monoamine oxidase A 2-kb promoter.

3 Low monoamine oxidase A activity increased risk for conduct

4 NIRKO mice also exhibit increased levels of monoamine oxidase A and B (MAO A and B) leading to incre

5 In a screening for potential monoamine oxidase A and B inhibition ciproxifan showed e

6 the central nervous system which is rich in monoamine oxidase A and B.

7 ted high selectivity (>160x) against related monoamine oxidase A and B.

8 Cloning of MAO (monoamine oxidase) A and B has demonstrated unequivocall

9 eas was similarly modulated by inhibition of monoamine oxidase-A and was reduced in animals with indu

10 tion and activity of recombinant human liver monoamine oxidases A and B (MAO A and B).

11 dent amine oxidizing enzymes including human monoamine oxidases A and B (MAO A and MAO B) show aromat

12 The monoamine oxidases A and B (MAO-A and -B) genes, which a

13 Monoamine oxidases A and B (MAO-A and MAO-B) are enzymes

14 rs with notable selectivity toward SSAO over monoamine oxidases A and B (MAO-A and MAO-B).

15 cture (which also has inhibitory activity at monoamine oxidases A and B and at the serotonin and nore

16 d binding to the norepinephrine transporter, monoamine oxidase A, and alpha2-adrenoceptors were measu

17 ty towards acetyl/butyrylcholinesterases and monoamine oxidases A/B as well as the histamine H3 recep

18 The degree of inhibition of monoamine oxidase A by R1 correlated with the level of R

19 ors, the sequences of three Sp1 sites in the monoamine oxidase A core promoter were used in the yeast

20 ryptophan hydroxylase 1 and a suppression of monoamine oxidase A expression (enzymes responsible for

21 gnificant association between high levels of monoamine oxidase A expression and poorly differentiated

22 e shown that the Sp1 family is important for monoamine oxidase A expression.

23 Monoamine oxidase A gene (MAOA) has earned the nickname

24 his study shows that glucocorticoid enhances monoamine oxidase A gene expression by 1) regulation of

25 Studies on the regulation of monoamine oxidase A gene expression have shown that the

26 s that R1 is a novel repressor that inhibits monoamine oxidase A gene expression.

27 Human monoamine oxidase A (hMAOA) is considered to be unique a

28 tor), SERT RNA-interference, and iproniazid (monoamine oxidase-A inhibitor), blocked 5-HT-induced S10

29 the current study, we used a genetic model (monoamine oxidase-A knockout mouse) in which brain 5-HT

30 The monoamine oxidase A locus (MAOA) at Xp11 was considered

31 quencies of a microsatellite and RFLP at the monoamine oxidase A locus in bipolar affective disorder

32 near the covalent 8alpha-S-cysteinyl FAD in monoamine oxidase A (MAO A) and to test the suggestion t

33 Monoamine oxidase A (MAO A) degrades serotonin, norepine

34 The FAD binding site of human liver monoamine oxidase A (MAO A) has been investigated by mut

35 Mice deficient in monoamine oxidase A (MAO A) have elevated brain levels o

36 ly shown that the serotonin-degrading enzyme monoamine oxidase A (MAO A) is an important source of hy

37 Inhibition of monoamine oxidase A (MAO A) is believed to cause antidep

38 Smokers have reduced levels of brain monoamine oxidase A (MAO A) leading to speculation that

39 A spontaneous monoamine oxidase A (MAO A) mutation (A863T) in exon 8 i

40 Monoamine oxidase A (MAO A) plays a central role in the

41 The interaction of recombinant human liver monoamine oxidase A (MAO A) with a series of phenethylam

42 The genetic deletion of monoamine oxidase A (MAO A), an enzyme that breaks down

43 Monoamine oxidase A (MAO A), encoded by the X chromosome

44 Converging evidence shows that monoamine oxidase A (MAO A), the key enzyme catalyzing s

45 However, it has been reported that monoamine oxidase A (MAO A, a major neurotransmitter-deg

46 by increased blood glucocorticoids and brain monoamine oxidase A (MAO A, which degrades monoamine neu

47 Monoamine oxidase A (MAO(A)) knockout mice have highly e

48 The use of selective inhibitors of monoamine oxidase A (MAO-A) and B (MAO-B) holds a therap

49 compared to linezolid but suffer from potent monoamine oxidase A (MAO-A) inhibition and low solubilit

50 Monoamine oxidase A (MAO-A) is a key enzyme in the catab

51 Monoamine oxidase A (MAO-A) is a key regulator of seroto

52 Monoamine oxidase A (MAO-A) is an important brain enzyme

53 Monoamine oxidase A (MAO-A) is an important enzyme on th

54 o counter the effects of the 40% increase in monoamine oxidase A (MAO-A) levels that occurs during PP

55 One such biological abnormality is elevated monoamine oxidase A (MAO-A) levels, which occurs in the

56 ylglycolaldehyde (DOPEGAL) is the neurotoxic monoamine oxidase A (MAO-A) metabolite of norepinephrine

57 hydroxyphenylglycolaldehyde (DOPEGAL) is the monoamine oxidase A (MAO-A) metabolite of norepinephrine

58 ating transcription of the gene encoding the monoamine oxidase A (MAO-A) to reduce serotonin levels i

59 We found that monoamine oxidase A (MAO-A) was the most significantly u

60 zolid (marketed as Zyvox), are inhibitors of monoamine oxidase A (MAO-A), which presents an undesired

61 ompanied by an increase in the expression of monoamine oxidase-A (MAO-A) and MAO-B in the lateral OFC

62 Monoamine oxidase-A (MAO-A) is a treatment target in neu

63 Monoamine oxidase-A (MAO-A), a key brain enzyme which me

64 cluding catechol-O-methyltransferase (COMT), monoamine oxidase-A (MAO-A), vesicular monoamine transpo

65 study examined how the mitochondrial enzyme monoamine oxidase-A (MAO-A), which produces hydrogen per

66 affinity to recombinant rat cerebral cortex monoamine oxidases A (MAO A) and B (MAO B) determined.

67 region contains, among others, the genes for monoamine oxidase A (MAOA) and B (MAOB), which are invol

68 We examined the impact of constitutive monoamine oxidase A (MAOA) deficiency in mice on nicotin

69 Mice lacking monoamine oxidase A (MAOA) display high levels of brain

70 A functional promoter polymorphism in the monoamine oxidase A (MAOA) gene has been implicated as a

71 examining allelic variation in the X-linked monoamine oxidase A (MAOA) gene, previously associated w

72 esonance imaging and genetic analysis of the monoamine oxidase A (MAOA) gene, we investigated how str

73 olymorphisms in dopamine receptor (DRD4) and monoamine oxidase A (MAOA) genes showed significant asso

74 (5HT) and the monoamine-metabolizing enzyme monoamine oxidase A (MAOA) have been repeatedly implicat

75 We report that monoamine oxidase A (MAOA) is a clinically and functiona

76 Monoamine oxidase A (MAOA) is a mitochondrial enzyme tha

77 The rs1137070 polymorphism of monoamine oxidase A (MAOA) is associated with alcoholism

78 ic mouse line in which the gene that encodes monoamine oxidase A (MAOA) is disrupted, resulting in ex

79 ohorts of Finnish prisoners, revealed that a monoamine oxidase A (MAOA) low-activity genotype (contri

80 Pharmacologic blockade of monoamine oxidase A (MAOA) or serotonin transporter (5-H

81 g growth differentiation factor-3 (GDF3) and monoamine oxidase A (MAOA) that is known to degrade nora

82 ing the neurotransmitter-metabolizing enzyme monoamine oxidase A (MAOA) was found to moderate the eff

83 6 member 2 (SLC6A2), an NE transporter, and monoamine oxidase A (MAOA), a degradation enzyme.

84 Monoamine oxidase A (MAOA), a mitochondria-bound enzyme,

85 cancer (PCa) exhibit increased expression of monoamine oxidase A (MAOA), a mitochondrial enzyme that

86 Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes m

87 polymorphisms affecting transcription level: monoamine oxidase A (MAOA), neuropeptide Y (NPY), endoth

88 Polymorphisms in the monoamine oxidase A (MAOA-LPR) and serotonin receptor 2A

89 hydroxyphenylglycolaldehyde (DOPEGAL) is the monoamine oxidase A metabolite of norepinephrine (NE) an

90 hydroxyphenylglycolaldehyde (DOPEGAL) is the monoamine oxidase A metabolite of norepinephrine and epi

91 3,4-Dihydroxyphenylglycolaldehyde is the monoamine oxidase-A metabolite of two catecholamine neur

92 luded those involved in cellular metabolism: monoamine oxidase-A, mitochondrial-A synthase complex, a

93 re was a main effect of adversity but not of monoamine oxidase A on risk for conduct disorder.

94 tistically significant effects on binding to monoamine oxidase A or to the norepinephrine transporter

95 R1 was also found to repress monoamine oxidase A promoter activity within a natural c

96 toma cell line, SK-N-BE (2)-C, inhibited the monoamine oxidase A promoter and enzymatic activity.

97 R1 also bound directly to the natural monoamine oxidase A promoter in vivo as shown by chromat

98 ith clorgyline, an irreversible inhibitor of monoamine oxidase A, restored hippocampal noradrenaline

99 A deficiency in monoamine oxidase A results in aggressive behavior in bo

100 rine secretion; P < 0.01), with no effect on monoamine oxidase A (serotonin catabolism), serotonin re

101 These carbamates are selective monoamine oxidase A substrates.

102 -serotonin and increased after inhibition of monoamine oxidase-A, the main enzyme responsible for ser