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1 nts (eg, a MEK inhibitor and/or an anti-CD20 monoclonal antibody).
2 HAstV are resistant to a virus-neutralizing monoclonal antibody.
3 tform was modified with anti-E. coli O157:H7 monoclonal antibody.
4 ynthesised as peptides for the production of monoclonal antibody.
5 y, but no correlation with the anti-carp PAV monoclonal antibody.
6 d nanoparticles conjugated with an anti-CD38 monoclonal antibody.
7 recipient mice with anti-IP-10 neutralizing monoclonal antibody.
8 ould also be precipitated with a PS-specific monoclonal antibody.
9 ceptor-null mice that were administered GcgR monoclonal antibody.
10 ika virus with a highly specific immobilized monoclonal antibody.
11 ccine or treatment with one or a cocktail of monoclonal antibodies.
12 lbumin with nanomolar affinity for all three monoclonal antibodies.
13 cine development and the prophylactic use of monoclonal antibodies.
14 cloning and characterizing large numbers of monoclonal antibodies.
15 some inhibitors, immunomodulatory drugs, and monoclonal antibodies.
16 by a panel of amyloid conformation-specific monoclonal antibodies.
17 ations for biotherapies such as vaccines and monoclonal antibodies.
18 raxane) nanoparticles coated with commercial monoclonal antibodies.
19 chromatography resin during purification of monoclonal antibodies.
20 ome inhibitors, immunomodulatory agents, and monoclonal antibodies.
21 ity in extracellular recognition of GPCRs by monoclonal antibodies.
24 local administration at the inflamed site of monoclonal antibody 3-E7, which recognizes the pan-opioi
25 last enrichment technique to isolate a human monoclonal antibody, 46B8 that neutralizes all IBVs test
27 d by immunohistochemistry, using 2 different monoclonal antibodies against a major antigen of varicel
31 tive enzyme-linked immunosorbent assays with monoclonal antibodies against PfLDH or PfIDEh showed det
33 While broadly cross-reactive, protective monoclonal antibodies against the haemagglutinin of infl
34 old chip containing an antifouling layer and monoclonal antibodies against the toxin and, after washi
36 ion of aGVHD-associated lymphangiogenesis by monoclonal antibodies against vascular endothelial growt
37 A. marginale infection of host cells, but a monoclonal antibody against 6-sulfo-sLe(x) fails to inhi
39 l characterization of a functional felinized monoclonal antibody against feline panleukopenia virus.
40 A previous study suggested that the 18B7 monoclonal antibody against glucuronoxylomannan (GXM), t
41 s have shown that trastuzumab, a recombinant monoclonal antibody against HER2 receptor, significantly
42 ate the efficacy and safety of simtuzumab, a monoclonal antibody against LOXL2, in patients with IPF.
45 during long-term therapy with evolocumab, a monoclonal antibody against proprotein convertase subtil
46 with PH were treated with Infliximab (IFX, a monoclonal antibody against TNF) and its impact on modul
49 osuppression with alemtuzumab (aIRR = 3.12), monoclonal antibodies (aIRR = 1.83), or polyclonal antib
50 holesterol (LDL-C) reductions with the PCSK9 monoclonal antibody alirocumab may be affected by backgr
51 or classes of effective agents in WM include monoclonal antibodies, alkylating agents, purine analogs
54 p53 is inaccessible to classical therapeutic monoclonal antibodies, an increasingly successful class
55 proaches are emerging including antagonistic monoclonal antibodies and agonistic fusion proteins to i
56 asured by antigenic analysis with a panel of monoclonal antibodies and by detecting changes in oligom
57 nted in combination therapies with anti-CD20 monoclonal antibodies and open up novel avenues for the
58 ght into chemical degradation in full-length monoclonal antibodies and the high-resolution hydrogen-e
60 the workflow to three-part assemblies for a monoclonal antibody and its single-chain antibody fragme
64 hnique to express antigen-specific felinized monoclonal antibodies, and the initial characterization
65 ts who received daratumumab, a CD38-directed monoclonal antibody approved for the treatment of multip
66 IL-4c; recombinant IL-4 mixed with anti-IL-4 monoclonal antibody as a stabilizer) was administered af
67 1B/D agonist sumatriptan and a CGRP-blocking monoclonal antibody, attenuated the peripheral CGRP-indu
68 ents and collection of clinical samples, the monoclonal antibody based antigen detection method from
69 ment of improved therapeutic approaches, and monoclonal antibody-based drugs are potentially a powerf
71 lopment and technical validation of a rabbit monoclonal antibody-based sandwich immunoassay for human
72 that antisera from immunized mice inhibited monoclonal antibody binding to neutralizing epitopes.
74 demic, and induction of broadly neutralizing monoclonal antibodies (bNAbs) against HCV is a major goa
75 ethodology to characterize residual HCPs in (monoclonal) antibodies by combining a novel sample prepa
76 ecent clinical trials showing that anti-CGRP monoclonal antibodies can reduce and even prevent migrai
77 roprotein convertase subtilisin/kexin type 9 monoclonal antibodies can reduce low-density lipoprotein
78 of TcdB neutralization by PA41, a humanized monoclonal antibody capable of neutralizing TcdB from a
79 and then perfused with a humanized anti-CD47 monoclonal antibody (CD47mAb) in the treatment group or
80 culatory cessation, then flushed with a CD47 monoclonal antibody (CD47mAb) in the treatment group, or
81 EMENT Calcitonin gene-related peptide (CGRP) monoclonal antibodies (CGRP-mAbs) are capable of prevent
82 NT Recently, we reported that humanized CGRP monoclonal antibodies (CGRP-mAbs) prevent activation and
83 h to migraine treatment, humanized anti-CGRP monoclonal antibodies (CGRP-mAbs) were developed to redu
84 new class of such drugs, humanized anti-CGRP monoclonal antibodies (CGRP-mAbs), were found to be effe
85 re the modified beads (mouse anti-flavivirus monoclonal antibody-coated beads) in the microfluidic ch
86 been made in the development of vaccines and monoclonal antibody cocktails that target the Ebola coat
95 tudy is to compare results associated with 3 monoclonal antibodies directed against the CD40/CD154 T
101 e and db/db mice that were administered GcgR monoclonal antibody displayed lower blood glucose levels
102 dditional infectious pathogens.DNA-delivered monoclonal antibodies (DMAbs) can be produced by muscle
108 ransducer functionalized with antidengue NS1 monoclonal antibodies for rapid detection of the dengue
110 ning Bloch surface waves are tailored with a monoclonal antibody for highly specific biological recog
112 highlight the importance of CDCC and CDCP in monoclonal-antibody function and provide an experimental
113 DC-targeting vaccines, humanized recombinant monoclonal antibodies fused to Env gp140, were administe
114 izing the Ncad extracellular domain with the monoclonal antibody GC-4 suppresses lateral dispersal an
116 he PD-1/PD-L1 immune checkpoint pathway with monoclonal antibodies has provided significant advances
118 tinguished by amyloid conformation-dependent monoclonal antibodies have similarly distinct roles in p
120 ncement toward broader practical delivery of monoclonal antibody immunotherapeutics for additional in
121 rs are capable of outperforming high-quality monoclonal antibodies in a standard ELISA detection assa
123 nderstanding the potential benefits of PCSK9 monoclonal antibodies incremental to statins in on-going
124 efficacy and safety of teprotumumab, a human monoclonal antibody inhibitor of IGF-IR, in patients wit
125 S-5745, a potent, highly selective humanized monoclonal antibody inhibitor of MMP9, has shown promise
129 efficacy, and pharmacokinetics of anti-CD38 monoclonal antibody isatuximab given in 2 schedules (3,
131 IIA (FcgammaRIIA), infusion of the HIT-like monoclonal antibody KKO increased fibrin and platelet de
133 o enable the detailed epitope mapping of two monoclonal antibodies known to recognize AGPs: JIM16 and
134 t given in combination with tumor-opsonizing monoclonal antibodies, KWAR23 greatly augments myeloid c
135 ized anticarcinoembryonic antigen (anti-CEA) monoclonal antibody, labetuzumab, can be used as a tumor
137 manized anti-folate receptor alpha (FRalpha) monoclonal antibody linked to the tubulin-disrupting may
142 rinciple of this method is based on the BChE monoclonal antibody (MAb) capable of acting as both capt
143 ng low side effect cancer therapy based on a monoclonal antibody (mAb) conjugated with a near-infrare
144 Eculizumab, a humanized anti-complement C5 monoclonal antibody (mAb) for treatment of paroxysmal no
149 th the F(ab')2 form of the anti-RSV G 131-2G monoclonal antibody (MAb) show that mutating the CX3C mo
150 en-printed electrode (AuSPE), and afterwards monoclonal antibody (mAb) specific to l-kynurenine was c
154 of DC-STAMP in periodontitis, anti-DC-STAMP-monoclonal antibody (mAb) was tested in a mouse model of
155 Administration approved the first biosimilar monoclonal antibody (mAb), Inflectra/Remsima (Celltrion)
161 r interaction with a group of alpha-JUNV GPC monoclonal antibodies (MAbs) and mouse antisera against
162 he ability to bind RBD-specific neutralizing monoclonal antibodies (MAbs) and the DPP4 receptor, and
163 l Hodgkin lymphoma (cHL) patients, anti-PD-1 monoclonal antibodies (mAbs) are increasingly being used
169 Intraperitoneally administered radiolabeled monoclonal antibodies (mAbs) have been tested in several
170 ir high affinities and specificities, rabbit monoclonal antibodies (mAbs) have demonstrated value and
173 undreds of labeled hybridoma cells producing monoclonal antibodies (mAbs) specific for a hapten were
175 is to evaluate the antibacterial activity of monoclonal antibodies (MAbs) targeting outer membrane pr
179 Here, we generated a panel of eight murine monoclonal antibodies (MAbs) utilizing a prime-boost vac
180 obtain large quantities of antigen-specific monoclonal antibodies (mAbs) were first established in t
181 and tumor delivery of a panel of anti-EphA2 monoclonal antibodies (mAbs) with and without drug conju
183 mically conjugated to two different anti-HIV monoclonal antibodies (MAbs), anti-gp120 MAb 924 or anti
184 tibodies (PAbs) or RSV glycoprotein-specific monoclonal antibodies (MAbs), as determined by indirect
185 the design of antiviral therapies, including monoclonal antibodies (mAbs), have naturally relied exte
187 wnregulation of CD20, a molecular target for monoclonal antibodies (mAbs), is a clinical problem lead
190 es designed to initiate new responses (e.g., monoclonal antibodies [mAbs], chimeric antigen receptors
191 ave the potential to outperform conventional monoclonal antibodies, many bispecific antibodies have i
192 rains, so induction of multiple neutralizing monoclonal antibodies (NAbs) targeting distinct epitopes
193 passive immunization with human neutralizing monoclonal antibodies (nmAbs) has made exciting gains: (
194 t glucagon receptor (GCGR) inhibition with a monoclonal antibody normalized blood glucose and beta-hy
195 Therapeutic and diagnostic applications of monoclonal antibodies often require careful selection of
199 c blockade of FcRn-albumin interactions with monoclonal antibodies or peptide mimetics, which cause h
200 nancies or solid tumors by administration of monoclonal antibodies or T cells engineered to express c
201 s are not detected by conformation-sensitive monoclonal antibodies or through electron microscopy ana
203 hat addition of an integrin beta1-activating monoclonal antibody, P4G11, to invasive colorectal cance
204 rformed structural studies on a neutralizing monoclonal antibody, PA50, a humanized mAb with both pot
206 e interaction between GDF15 and GFRAL with a monoclonal antibody prevented the metabolic effects of G
207 however, there are at least 50 vaccines and monoclonal antibody products in development, with those
210 utralization of asprosin in the blood with a monoclonal antibody reduced appetite and body weight in
212 rolled intravenous delivery of a novel mouse monoclonal antibody replacement therapy, which acts as a
214 tment with anti-TNF-alpha or anti-IL-4Ralpha monoclonal antibodies restored the TH1- and TH2-induced
217 e a novel approach to produce conformational monoclonal antibodies selected to specifically react wit
218 rolled protein-expressing cell lines using 6 monoclonal antibodies (SP142, E1L3N, 9A11, SP263, 22c3,
220 y of tezepelumab (AMG 157/MEDI9929), a human monoclonal antibody specific for the epithelial-cell-der
221 was also shown to bind D25, a highly potent monoclonal antibody specific for the pre-F conformation.
222 of our method to analyze a high-purity NIST monoclonal antibody standard RM 8670 derived from a muri
224 In particular, the use of function blocking monoclonal antibodies targeting checkpoint inhibitors su
226 the envelope glycoprotein 1 (GP1) with JUNV monoclonal antibodies targeting the receptor binding sit
227 alf-life (eg, FVIII-Fc and PEGylated FVIII), monoclonal antibodies targeting tissue factor pathway in
229 of pyrrolobenzodiazepine dimers linked to a monoclonal antibody targeting CD33, which is expressed i
233 hibit tumor growth in vitro and in vivo by a monoclonal antibody targeting the AGR2 self-dimerization
234 lular Hsp90alpha-Delta protein function by a monoclonal antibody targeting the fragment-5 region disr
235 -expressing xenografts, using the bispecific monoclonal antibody TF2 (anti-CEA x anti-histamine-succi
236 TGF-beta1-specific, humanized, neutralizing monoclonal antibody (TGF-beta1 mAb) is safe and more eff
237 for cancer are typically small molecules or monoclonal antibodies that act by inhibiting the activit
240 Using epitope mapping, we discovered mouse monoclonal antibodies that can discriminate between huma
241 make possible the rapid development of human monoclonal antibodies that could become a potent immedia
242 Here, we obtained two anti-A(H1N1)pdm09 HA monoclonal antibodies that failed to neutralize viruses
246 ted nearly identical binding profiles to HCV monoclonal antibodies that target conserved neutralizing
250 nd by the Fab fragment of mAb35, a reference monoclonal antibody that causes experimental MG and comp
251 humanised, anti-interleukin 5 receptor alpha monoclonal antibody that directly and rapidly depletes e
252 inophilic, anti-interleukin-5 receptor alpha monoclonal antibody that has been shown to significantly
253 CAT-354) is an IL-13-neutralising human IgG4 monoclonal antibody that has shown clinical benefit in p
254 d risankizumab (BI 655066), a humanized IgG1 monoclonal antibody that inhibits interleukin-23 by spec
255 anised antiprogrammed death-ligand 1 (PD-L1) monoclonal antibody that inhibits PD-L1 and programmed d
262 olavirus species, and the mechanism of these monoclonal antibody therapeutics is still not understood
263 negative predictors of benefit to anti-EGFR monoclonal antibody therapies for targeted therapy of CR
265 fficacy and the mechanisms of action of CD19 monoclonal antibody therapy in pediatric BCP-ALL, we tes
266 he complementary binding region on all three monoclonal antibodies to be the CDR H3 loop of the Fab r
268 , we evaluated the capacity of anti-receptor monoclonal antibodies to deliver vaccine components to s
269 evaluated the therapeutic activity of human monoclonal antibodies to DENV EDE for their ability to c
270 ither of these IVIG fragments, nor agonistic monoclonal antibodies to human Fas or Siglec-9 affected
276 erved even when the mice were treated with a monoclonal antibody to eliminate residual granulocyte ac
277 C) takes advantage of the selectivity of the monoclonal antibody to increase the efficacy of the chem
280 safety in the FOURIER trial of evolocumab, a monoclonal antibody to proprotein convertase subtilisin-
282 Infusion of a T-cell-depleting anti-CD8beta monoclonal antibody to the controller animals led to a s
283 Treatment of C57BL/6 or NOD mice with a monoclonal antibody to the CSF-1 receptor resulted in de
284 Treatment with the anti-ERBB2 humanized monoclonal antibody trastuzumab and chemotherapy signifi
285 effect of targeting this receptor using the monoclonal antibody TRC105, and find that in AML, TRC105
286 haracterize the epitope specificities of two monoclonal antibodies used in an ELISA for the quantific
288 tested the binding breadth of the resulting monoclonal antibodies using a set of recombinant surface
293 ultifunctional HNPs conjugated with anti-MG1 monoclonal antibodies were synthesized, and the coupling
294 e inhibitory RGMa, clinically relevant human monoclonal antibodies were systemically administered aft
295 breadth of cross-reactive neutralization by monoclonal antibodies, whether engineered or isolated fr
296 sm of C. difficile toxin neutralization by a monoclonal antibody, which involves targeting a process
297 selective for the heavy and light chain of a monoclonal antibody, which when used consecutively, ensu
299 anti-epidermal growth factor receptor (EGFR) monoclonal antibodies with radiotherapy (RT) to standard
300 the structure of the epitope recognized by a monoclonal antibody with opsonophagocytic activity and r
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