ライフサイエンスコーパス: monoclonal immunoglobulin

1 a ratio is used to determine the presence of monoclonal immunoglobulin.

2 enotypes characterized by over-production of monoclonal immunoglobulins.

3 esults in overproduction of large amounts of monoclonal immunoglobulins.

4 We used a human monoclonal immunoglobulin A (IgA) antibody (NAD) to type

5 2D6 is a dimeric monoclonal immunoglobulin A (IgA) specific for the nonre

6 We tested the ability of a human monoclonal immunoglobulin-A (IgA) antibody specific for

7 alence of MGUS and characterized patterns of monoclonal immunoglobulin abnormalities prior to MM diag

8 itrogen (BUN), supernatant IL-4, serum IL-6, monoclonal immunoglobulin and beta2-microglobulin, as we

9 a (MM) is characterized by the production of monoclonal immunoglobulin and is associated with suppres

10 mu) N3 mice overexpressed Myc(His), produced monoclonal immunoglobulin, and exhibited a unique plasma

11 we present a proof of concept screening for monoclonal immunoglobulin as a leukemia tumor marker usi

12 c lymphocytic leukemia (B-CLL) cells express monoclonal immunoglobulins carrying either kappa or lamb

13 ndings and outcome in 34 patients with renal monoclonal immunoglobulin deposition disease (MIDD), whi

14 common entities are light chain amyloidosis, monoclonal immunoglobulin deposition disease and myeloma

15 ight chain amyloidosis (AL) are disorders of monoclonal immunoglobulin deposition in which normally s

16 myeloma, is usually related to deposition of monoclonal immunoglobulin free light chains (FLCs) and d

17 Monoclonal immunoglobulin free light chains (FLCs) are u

18 s) are directly related to the production of monoclonal immunoglobulin free light chains (FLCs), whic

19 Although both polyclonal and monoclonal immunoglobulin G (IgG) inhibited secondary pr

20 and adapted interface for the attachment of monoclonal immunoglobulin G (IgGNS1) and to favor specif

21 dL monoclonal peak in the gamma region, with monoclonal immunoglobulin G and lambda light chain detec

22 Among 34 patients (91.9%) with monoclonal immunoglobulin G gammopathy, 20 (58.8%) had k

23 As a result, isotopic resolution of monoclonal immunoglobulin G was achieved, and we have es

24 ification and characterization of two murine monoclonal immunoglobulin G1 antibodies (MAbs), 1-F1 and

25 ab, formerly IMC-A12, is a recombinant human monoclonal immunoglobulin G1 antibody that targets insul

26 a high-affinity engineered human anti-PD-L1 monoclonal immunoglobulin-G1 antibody that inhibits the

27 AMG 157 is a human anti-TSLP monoclonal immunoglobulin G2lambda that binds human TSLP

28 -936558 (MDX-1106) - a fully human anti-PD-1 monoclonal immunoglobulin-G4 that blocks ligand binding

29 isoform of the light chain of a fully human monoclonal immunoglobulin gamma2 (IgG2) antibody panitum

30 Our studies reveal that different monoclonal immunoglobulin Gs (IgGs) and chimeric IgGs sh

31 eritubular amorphous deposits of a truncated monoclonal immunoglobulin heavy chain (HC) bearing a del

32 s is a protein misfolding disease in which a monoclonal immunoglobulin (Ig) light chain (LC) with a c

33 plasma cell dyscrasia in which the secreted monoclonal immunoglobulin (Ig) light chains form amyloid

34 The many binding studies of monoclonal immunoglobulin (Ig) produced by plasmacytomas

35 All cases showed monoclonal immunoglobulin (IG) rearrangement.

36 ith kidney disease through the production of monoclonal immunoglobulin (Ig).

37 ith kidney disease through the production of monoclonal immunoglobulin (Ig).

38 ted and led to reduction in tumor-associated monoclonal immunoglobulin in 3 of 4 patients with measur

39 yloid fibrils composed of amyloid A protein, monoclonal immunoglobulin lambda light chain, Leu60Arg v

40 yretin (senile systemic amyloidosis, SSA) or monoclonal immunoglobulin light chain (AL amyloidosis).

41 Deposition of monoclonal immunoglobulin light chain (LC) aggregates in

42 s is correlated with the overproduction of a monoclonal immunoglobulin light chain protein by a B-lym

43 ng from systemic extracellular deposition of monoclonal immunoglobulin light chain variable domains i

44 (AL) results from overproduction of unstable monoclonal immunoglobulin light chains (LCs) and the dep

45 n incurable protein misfolding disease where monoclonal immunoglobulin light chains misfold and depos

46 is a protein conformation disorder in which monoclonal immunoglobulin light chains produced by clona

47 e deposition of amyloid fibrils derived from monoclonal immunoglobulin light chains.

48 osition of fibrils in patients overproducing monoclonal immunoglobulin light chains.

49 idosis-including heart involvement of either monoclonal immunoglobulin light-chain (AL) or transthyre

50 acytic infiltration of the bone marrow and a monoclonal immunoglobulin M (IgM) protein.

51 (i.p.) administration of radiolabeled human monoclonal immunoglobulin M (IgM), which is reactive wit

52 plasmacytic expansion accompanied by a serum monoclonal immunoglobulin M (IgM).

53 ation between VWF levels < 130 U/dL and both monoclonal immunoglobulin M concentration (mIgMC) and vi

54 the urine (>/=0.2 g/24 h), absence of intact monoclonal immunoglobulin (M protein) in the serum, and

55 We sought to characterize monoclonal immunoglobulin (M-Ig) light chains before cli

56 , and IgM; examined sera for the presence of monoclonal immunoglobulins (M proteins); and looked for

57 ght chains (FLCs), soluble CD30 (sCD30), and monoclonal immunoglobulins (M-proteins).

58 Therapeutic monoclonal immunoglobulins (mAbs) are used to treat pati

59 glomerulopathy (C3G) emphasizes the role of monoclonal immunoglobulin (MIg) in the occurrence of ren

60 121 (20%) had a monoclonal immunoglobulin or abnormal circulating free l

61 rns exist, they are all distinguished by the monoclonal immunoglobulin (or component) deposits.

62 g bone malignant plasma cell infiltration, a monoclonal immunoglobulin peak, immunoglobulin deposit i

63 The monoclonal immunoglobulin, secreted by myeloma plasma ce

64 ionship between the mucin deposition and the monoclonal immunoglobulins that are seen in almost all p

65 he hallmark biomarker in blood or urine is a monoclonal immunoglobulin, the monoclonal protein.

66 The binding of four monoclonal immunoglobulins, two with specificity for bet

67 idates having increased globulins.However, a monoclonal immunoglobulin was identified in only 3% of a

68 The concentration of monoclonal immunoglobulin was less than 1.0 g per decili