ライフサイエンスコーパス: monocular

1 ts of short-term exposure (2 or 48 hours) to monocular +10 and -10 diopter (D) lenses, on RPE gene ex

2 Six infants were reared with monocular -3 D lenses that produced relative hyperopic d

3 Anesthetized adult rats received monocular AC injections of a mixture of 3-kDa dextran-ca

4 Monocular accommodative lag to a 4-D Badal stimulus was

5 Monocular adaptation to one grating before the presentat

6 We observed a monocular advantage, which indicates subcortical facilit

7 was much larger (1.67 x, P < 0.01) than the monocular amplitude.

8 Most patients were functionally monocular and 80% had undergone 4 or more prior ocular s

9 o 6 months after surgery) with the following monocular and binocular assessments: high- and low-contr

10 ntile nystagmus syndrome and myopia improved monocular and binocular BCVA and contrast sensitivity.

11 isual system can switch effortlessly between monocular and binocular conditions.

12 with and without optical correction, and in monocular and binocular conditions; one condition was me

13 alens AO and ReSTOR +3.0 demonstrated better monocular and binocular contrast sensitivity without gla

14 modal versus unimodal responses of the adult monocular and binocular cortices also mirror regional sp

15 Comparison of the adaptation of the medial monocular and binocular cortices to long-term ME or dark

16 ight level on normal, age-related changes in monocular and binocular functional contrast sensitivity.

17 Here we show that, in rat monocular and binocular primary visual cortex (V1m and V

18 are consistent with this hypothesis for both monocular and binocular signals.

19 ibility to encode visual features under both monocular and binocular situations.

20 Our results suggest that structured monocular and binocular training are necessary to fully

21 TCOME MEASURE(S): Three-months-postoperative monocular and binocular UCVA and DCVA in 4 m, 80 cm, and

22 1 and 3 months included manifest refraction; monocular and binocular uncorrected (UCVA) and distance-

23 stalens AO demonstrated significantly better monocular and binocular uncorrected and distance-correct

24 The ReSTOR+3.0 lens had significantly better monocular and binocular uncorrected and distance-correct

25 The main outcome measures were monocular and binocular uncorrected distance (UDVA), cor

26 patients underwent: monocular defocus curve; monocular and binocular uncorrected visual acuity in pho

27 ed at the Wills Eye Institute using standard monocular and binocular VF testing, as well as an object

28 t to drive vergence eye movements under both monocular and binocular viewing conditions.

29 Monocular and binocular visual acuity (VA) and contrast

30 t there has been no systematic study on both monocular and binocular visual functions.

31 on calcium imaging to sample the response to monocular and binocular visual stimuli from nearly every

32 For monocular and interocular analyses, the average percenta

33 mask interact nonlinearly at two stages, one monocular and one binocular.

34 ferences among MM, sighted controls, sighted monocular, and early blind subjects.

35 These results suggest that monocular, and not binocular, mechanisms set the limit o

36 sed eye response that normally occurs in the monocular as well as binocular zone is delayed, but only

37 Monocular BCVA improved from 0.36 +/- 0.21 logMAR to 0.2

38 of the BEFIE test was assessed by comparing monocular BEFIE test results with those of standard conv

39 Comparison of monocular BEFIE tests with standard conventional perimet

40 Corneal ulcer, a major cause of monocular blindness in developing countries has consiste

41 The stimulus was made monocular by placing an infrared filter over the right e

42 Eyes treated for monocular cataract in infancy have axial growth similar

43 cro F, binocular UDVA, 0.01 logMAR +/- 0.05; monocular CDVA, 0.03 logMAR +/- 0.06; binocular UNVA, 0.

44 iple, contiguous, quasicoronal planes during monocular central gaze fixation.

45 Monocular corrected distance visual acuity (CDVA), corre

46 table for laser in situ keratomileusis, with monocular corrected distance visual acuity of 20/32 or b

47 ation remained incomplete, especially in the monocular cortex medial to V1.

48 In the medial monocular cortex, cortical inhibition via the GABAA rece

49 s followed by cross-modal adaptations in the monocular cortex, in which whiskers become a dominant no

50 .SIGNIFICANCE STATEMENT Motion parallax is a monocular cue to depth that commonly arises during obser

51 hysical tests with stimuli that contained no monocular cues and on clinical testing.

52 We used a training paradigm that combines monocular cues that were correlated perfectly with the d

53 One possibility is that the brain uses monocular cues to identify that a surface is specular an

54 stereoscope and a computerized test removing monocular cues.

55 Analysis included a monocular data set from single eyes of 97 subjects (age:

56 s established that amblyopia is not simply a monocular deficit, and therefore the most promising new

57 One month after surgery patients underwent: monocular defocus curve; monocular and binocular uncorre

58 The monocular defocus curves showed that the best visual acu

59 isual area V2 of monkeys reared with chronic monocular defocus.

60 Monocular defocusing lenses were worn for 10-15 days fro

61 Monocular defocusing lenses were worn for 5 days from 17

62 of in vivo cortical plasticity triggered by monocular deprivation (MD) and consolidated by sleep via

63 loping primary visual cortex is initiated by monocular deprivation (MD) and consolidated during subse

64 adult mice that visuomotor experience during monocular deprivation (MD) augmented enhancement of visu

65 In visual cortex monocular deprivation (MD) during a critical period (CP)

66 Monocular deprivation (MD) during a critical period of p

67 Here, we show that monocular deprivation (MD) during the adolescent critica

68 Monocular deprivation (MD) during the critical period (C

69 to recover cortical responsiveness following monocular deprivation (MD) during the critical period, a

70 Monocular deprivation (MD) during the visual critical pe

71 Monocular deprivation (MD) engages synaptic mechanisms o

72 Monocular deprivation (MD) imposed early in postnatal li

73 on dendritic spine turnover before and after monocular deprivation (MD) in adult V1 with chronic in v

74 f-century of research on the consequences of monocular deprivation (MD) in animals has revealed a gre

75 In layer 4 of visual cortex (V1), monocular deprivation (MD) induces either depression or

76 Monocular deprivation (MD) induces ocular dominance (OD)

77 Monocular deprivation (MD) is a classic paradigm for exp

78 Ocular dominance plasticity (ODP) following monocular deprivation (MD) is a model of activity-depend

79 Brief monocular deprivation (MD) shifts ocular dominance (OD)

80 Brief monocular deprivation (MD) shifts ocular dominance and r

81 , we visualized V1 activity before and after monocular deprivation (MD) using intrinsic signal optica

82 ocular dominance (OD) plasticity after brief monocular deprivation (MD) was severely impaired during

83 Also distinct from V1M, brief monocular deprivation (MD) was unable to modulate LTP-IE

84 te of ocular dominance change in response to monocular deprivation (MD), but also accelerated recover

85 We found that monocular deprivation (MD), but not binocular deprivatio

86 After brief monocular deprivation (MD), STAT1 knock-out (KO) mice sh

87 city in primary visual cortex in response to monocular deprivation (MD), the maturation of inhibition

88 at the onset of the critical period (CP) for monocular deprivation (MD), the period when MD can cause

89 ts on unit activity during the first 48 h of monocular deprivation (MD), we show that PNN removal res

90 reased sensitivity of excitatory synapses to monocular deprivation (MD).

91 e wave gratings for 6 h/d during a period of monocular deprivation (MD).

92 dominance (OD) shift in visual cortex after monocular deprivation (MD).

93 nd of promoting recovery from the effects of monocular deprivation (MD).

94 Depriving one eye of vision (monocular deprivation [MD]) during the critical period a

95 s receptor alters the microglial response to monocular deprivation and abrogates ocular dominance pla

96 e plasticity in identified neurons following monocular deprivation and affected the maturation of den

97 lar dominance (OD) plasticity resulting from monocular deprivation and stimulus-selective response po

98 lly induced activity-dependent plasticity by monocular deprivation caused rapid changes in single uni

99 sensitivity called the critical period (CP), monocular deprivation causes a shift in the response of

100 Monocular deprivation disrupts the binocular balance of

101 Monocular deprivation disrupts the binocular balance of

102 ll illustrated in mouse visual cortex, where monocular deprivation during early postnatal development

103 Here we show that brief monocular deprivation during the critical period downreg

104 responsiveness to open-eye stimulation after monocular deprivation during the critical period is a ho

105 We find that microglia respond to monocular deprivation during the critical period, alteri

106 binocular matching is completely blocked by monocular deprivation during the critical period.

107 y.SIGNIFICANCE STATEMENT We demonstrate that monocular deprivation during the developmental critical

108 Moreover, monocular deprivation elicited amblyopia only during a d

109 ng in vivo optical imaging, we observed that monocular deprivation in adult EE mice (i) caused a very

110 Although brief monocular deprivation in juvenile WT mice normally cause

111 al cortex and promotes recovery from chronic monocular deprivation in Long Evans rats.

112 We demonstrate that in mice long-term monocular deprivation increases oligodendrogenesis in th

113 Here we show that chronic monocular deprivation induces a significant decrease in

114 Chronic monocular deprivation induces severe amblyopia that is r

115 that a reduction in the NR2A/B ratio during monocular deprivation is permissive for the compensatory

116 -CP), whereas potentiation is induced if the monocular deprivation is started in the fourth postnatal

117 itivity of ocular dominance to regulation by monocular deprivation is the canonical model of plastici

118 Brief monocular deprivation leads to activation of CaMKII in m

119 Monocular deprivation of sharp vision (DSV) was induced

120 reeding experiment testing susceptibility to monocular deprivation of sharp vision (DSV).

121 tiation of open eye responses resulting from monocular deprivation relies on a homeostatic response t

122 binocular-like excitatory firing rates after monocular deprivation results from a rapid, although tra

123 For instance, a few days of monocular deprivation results in a robust reduction of c

124 ar matching process is completely blocked by monocular deprivation spanning the entire critical perio

125 In adult humans, short-term monocular deprivation strongly modifies ocular balance,

126 Loss of visual acuity in response to brief monocular deprivation was concomitantly delayed and resc

127 but did occur in wild-type littermates when monocular deprivation was imposed during the critical pe

128 ivity in V1 can be unmasked following 4 d of monocular deprivation when the mice older than 2 months

129 NT Microglia in the visual cortex respond to monocular deprivation with increased lysosome content, b

130 equence of occluding vision through one eye (monocular deprivation) is a rapid loss of excitatory syn

131 Monocular deprivation, a model of sensory input-dependen

132 After monocular deprivation, resting GABA concentration decrea

133 cells phenocopies the changes observed after monocular deprivation, suggesting that glutamate may con

134 male and female mice before and after a 7 d monocular deprivation, which allowed us to examine both

135 emoval of tPA in Lynx1 KO mice can block the monocular deprivation-dependent reduction of dendritic s

136 nce spectroscopy before and after short-term monocular deprivation.

137 cantly reduced the OD shift of EE mice after monocular deprivation.

138 ed by ocular dominance shifts in response to monocular deprivation.

139 ret visual cortex following brief periods of monocular deprivation.

140 l synapses, during the recovery from chronic monocular deprivation.

141 ex and that responded to dark rearing and/or monocular deprivation.

142 s or a shift in ocular dominance after brief monocular deprivation.

143 type 1 (PDE1) inhibitor during the period of monocular deprivation.

144 vely active form of SRF during the period of monocular deprivation.

145 ocular dominance plasticity (ODP) following monocular deprivation.

146 g recovery from amblyopia induced by chronic monocular deprivation.

147 g recovery from amblyopia induced by chronic monocular deprivation.

148 s already reached a matured level before the monocular deprivation.

149 wo eyes or changes in spines were altered by monocular deprivation: the changes occurred irrespective

150 eceptive fields (RFs) in response to complex monocular depth cues.

151 R] 0.69, 95% confidence interval 0.52-0.91), monocular deviation (OR 0.64), complex surgery (OR 1.63)

152 Using a monocular/dichoptic paradigm, across four experiments, w

153 age, nine infant monkeys were reared wearing monocular diffuser lenses that eliminated form vision in

154 The prevalence of monocular diplopia and binocular diplopia unrelated to g

155 All patients had preoperative monocular diplopia or unstable vision attributable to th

156 Monocular diplopia was found in a similar proportion of

157 diplopia), 1 (4%) optical/refractive error (monocular diplopia), 2 (8%) mixed retinal misregistratio

158 c disease, disruption of central fusion, and monocular diplopia.

159 raft folds may explain subjective reports of monocular diplopia.

160 visual acuity (UDVA), -0.01 logMAR +/- 0.06; monocular distance corrected visual acuity (CDVA), 0.02

161 med comprehensive eye examinations including monocular distance visual acuity (VA), cover testing, an

162 y of image quality increased due to extended monocular DoF.

163 Neural concomitants of this improvement in monocular dominance are reflected in measurements of bra

164 selected parents, was assessed after either monocular DSV (4 or 10 days) or lens wear.

165 Monocular enucleation (ME) drastically affects the contr

166 In adult mice, monocular enucleation (ME) results in an immediate deact

167 t when intereye competition is eliminated by monocular enucleation, blocking cholinergic stage II ret

168 ochrome oxidase (CO) activity patterns after monocular enucleation.

169 s lower than for hyperopic subjects for both Monocular Estimation Method (1.03 +/- 0.51 D vs 2.03 +/-

170 ar (P) and magnocellular (M) layers received monocular excitatory inputs.

171 y and facilitation of OD plasticity by prior monocular experience were both present in GluA1(-/-) mic

172 Subjects underwent monocular exposure to narrowband blue light (469 nm) or

173 and amount of activity in the dLGN following monocular eyelid closure and monocular retinal inactivat

174 Binocular and monocular FERGs had similar amplitudes.

175 Monocular FERGs were recordable from the stimulated eye

176 Integrated BVFs were calculated from the monocular fields of each patient.

177 ted binocular fields were estimated from the monocular fields.

178 These data indicate that early monocular form deprivation does not alter the segregatio

179 periods of unrestricted vision during early monocular form deprivation reduces the depth of amblyopi

180 Monocular form deprivation was imposed on eight infant r

181 Monocular form-deprivation was produced in 18 rhesus mon

182 12 normal monkeys and five monkeys that had monocular foveal ablations and were subsequently reared

183 these novel observations with insights from monocular, frontoparallel motion studies concurrently in

184 h and graded transitions from one apparently monocular functional domain to an adjacent binocular reg

185 S definitions, DME and CSME prevalences from monocular fundus photographs (28.5% and 21.0%, respectiv

186 ross-sectional study of DME grading based on monocular fundus photographs and OCT images obtained fro

187 eyes diagnosed as not having DME or CSME on monocular fundus photographs have DME on OCT.

188 many eyes diagnosed as having DME or CSME on monocular fundus photographs have no DME based on OCT CS

189 Prevalence of DME based on monocular fundus photographs or OCT.

190 nically significant macular edema (CSME), on monocular fundus photographs used definitions from the M

191 12.9%-24.2%) were diagnosed as having DME on monocular fundus photographs using MESA and NHANES defin

192 ot diagnosed as having either DME or CSME on monocular fundus photographs using MESA and NHANES defin

193 d CSME (48.5%) based on MESA definitions for monocular fundus photographs were greater than the DME p

194 Diagnosing diabetic macular edema (DME) from monocular fundus photography vs optical coherence tomogr

195 ies and telemedicine screening typically use monocular fundus photography, while treatment of DME use

196 to obtain MIC values from 221 patients with monocular fungal keratitis.

197 The model involves monocular gain controls with interocular suppression fro

198 Transient or persistent monocular ghost images or diplopia occurred in 10 of 178

199 gle units in area MT, measuring responses to monocular gratings and plaids, and to dichoptic plaids i

200 The purpose of this study was to compare the monocular Humphrey Visual Field (HVF) with the binocular

201 Early results demonstrate that monocular IC-8 intraocular lens implantation provides a

202 43 White-Leghorn chickens that had undergone monocular ID.

203 be induced by prior, extended viewing of two monocular images differing only in contrast.

204 produce the normal physiological response to monocular impairments.

205 -Fos, and zinc finger protein, Zif268, after monocular inactivation (MI) to identify ODCs in V1 of Ne

206 Monocular infantile blindness may be associated with bil

207 ed of dynamic random dots to remove coherent monocular information.

208 tation in visual and non-visual areas during monocular interferences.

209 Two groups of five tree shrews started monocular lens wear 24 days after eye opening (days of v

210 lthough amblyopia is diagnosed in terms of a monocular letter acuity loss, individuals typically pres

211 Monocular lid closure (MC) causes a profound shift in th

212 reduction in PV-cell-evoked responses after monocular lid suture is restricted to the critical perio

213 Visual modification with monocular lid suturing reduced correlation between left

214 oice procedures were utilized to measure the monocular log minimal angle of resolution (logMAR) visua

215 Outcome measures were monocular logarithm of the minimum angle of resolution (

216 Outcome measures were monocular logMAR visual acuity scores for each test: ETD

217 cted VA than the ReSTOR +3.0 and better mean monocular low-contrast DCVA than the Tecnis Multifocal l

218 with retinal outputs maintained as separate monocular maps en route through the lateral geniculate n

219 These results reveal the role of monocular mechanisms in the computation of pattern motio

220 blood glucose (BG) concentration, HbA1c, and monocular mfERG were performed on 115 adolescent patient

221 oveal optokinetic contribution suggests that monocular nasotemporal optokinetic asymmetry is partly a

222 to play an important role in maintaining the monocular nasotemporal optokinetic asymmetry seen in pat

223 The initial screening included testing of monocular near and distance visual acuity, stereoacuity,

224 te in dense "cyclopean" images containing no monocular objects.

225 nkeys reared under conditions of alternating monocular occlusion during their first few months of lif

226 proportions of missed steps before and after monocular occlusion showed that monocular visual informa

227 the esodeviated eye can supplement temporal monocular optokinetic responses in the fixating eye unde

228 Monocular optotype acuity was assessed at 4(1/2) years o

229 dging visuotactile simultaneity after either monocular or binocular deprivation.

230 clinically affected family members exhibited monocular or binocular supraduction deficits, three in t

231 Using monocular or binocular visual deprivation, we examined t

232 of mouse simple cells is nearly identical to monocular orientation selectivity in both anaesthetized

233 ects in a control group were investigated by monocular pattern electroretinogram (ERG), L&M (long and

234 of the retinal nerve fiber layer (RNFL), and monocular pattern reversal visually evoked potentials (p

235 l for in-phase and antiphase conditions, and monocular presentation, but increased a little at interm

236 presented to non-overlapping regions of the (monocular) receptive field.

237 P of intrinsic excitability (LTP-IE)] in the monocular region of the primary visual cortex (V1M) play

238 eriods, whereby low-SF regions coincide with monocular regions.

239 isible to both eyes do indeed form part of a monocular representation of the contralateral visual fie

240 effects of this treatment, the binocular and monocular response properties of neurons were quantitati

241 Comparing the monocular results to the binocular results there was a s

242 7BL/6 mice that underwent 3 and 7 d of MC or monocular retinal inactivation (MI) with tetrodotoxin.

243 dLGN following monocular eyelid closure and monocular retinal inactivation in awake mice.

244 depth and thus require the co-ordination of monocular saccade amplitudes and binocular vergence eye

245 inocular visual field was estimated from the monocular SAP tests, and rates of change in mean sensiti

246 score was less than that of the better eye's monocular score).

247 plitude of mEPSCs and were restricted to the monocular segment contralateral to the deprived eye.

248 ion occurs after spatiotemporal filtering of monocular signals, which leads to restrictions on dispar

249 rivation, GABA concentration measured during monocular stimulation correlated with the deprived eye d

250 ratio of excitation to inhibition evoked by monocular stimulation decreased mainly for nonpreferred

251 sponses were weaker with binocular than with monocular stimulation.

252 ve response to at least the 0.75 D amplitude monocular stimulus and the 0.75 and 0.50 D binocular sti

253 (1-4) numbers of dots, is facilitated in the monocular, subcortical portions of the visual system.

254 label technique in three animals raised with monocular suture.

255 f 127 subjects, 11 (8.7%) could not complete monocular TAC testing in either eye; 39 (30.7%) could no

256 In interocular suppression, a suprathreshold monocular target can be rendered invisible by a salient

257 lasticity of binocular cortical neurons used monocular tests of ocular dominance to infer binocular f

258 nstrate the benefit of binocular relative to monocular text presentation for both parafoveal and fove

259 Monocular threshold VA was tested using a single-surroun

260 ring response in the fellow eye when using a monocular trial eliminates the need for additional offic

261 The monocular trial of therapy is effective in accurately pr

262 3-0.76), and the effect when adjusted by the monocular trial was 0.72 (95% CI, 0.49-0.86).

263 The mean monocular UDVA, UIVA, and UNVA improved significantly fr

264 loyed in the present study improved both the monocular VA of the AE and stereofunction, verifying the

265 omprehensive ophthalmic evaluation including monocular VA testing, cover testing, cycloplegic autoref

266 X-like cells were confined primarily to the monocular ventral region of dLGN.

267 consequences for either pairing differ after monocular versus binocular deprivation [8-11].

268 Participants underwent monocular VF testing in both eyes using a Humphrey Field

269 Monocular VFs were scored according to the mean defect,

270 onviewing (mean, 39.7% +/- 6.2%) eyes during monocular viewing conditions, even in cases with large a

271 widths at two distances under binocular and monocular viewing conditions.

272 mooth pursuit (0.2 Hz, +/-10 degrees ) under monocular viewing conditions.

273 human infants and adults under binocular and monocular viewing conditions.

274 We tested smooth pursuit adaptation during monocular viewing in strabismic monkeys with exotropia.

275 With monocular viewing, maximum grip aperture (MGA) increased

276 he left and right, during both binocular and monocular viewing.

277 iority of visual function for binocular over monocular viewing.

278 as they performed eye movement tasks during monocular viewing.

279 greater during binocular viewing than during monocular viewing.

280 velopmental visual disorder that alters both monocular vision and binocular interaction.

281 ked reduction in horizontal eye velocity and monocular visual acuity improved to 20/80.

282 nt comprehensive eye examinations, including monocular visual acuity testing, stereoacuity testing, a

283 Monocular visual acuity was tested using both the new ey

284 neurons in the same region of the layer 2/3 monocular visual cortex following enucleation.

285 of GABAergic signaling in layer 2/3 of mouse monocular visual cortex.

286 ate deactivation of the contralateral medial monocular visual cortex.

287 Plasticity produced by monocular visual deprivation (MD) has been dissected int

288 ortex of freely behaving rats during chronic monocular visual deprivation (MD).

289 short period of time: contrary to intuition, monocular visual deprivation actually improves the depri

290 Following monocular visual deprivation during the critical period,

291 Here, we show that monocular visual deprivation enhances GABAergic synaptic

292 Monocular visual field (VF) and visual acuity (VA) tests

293 ssesses two distinct visual fields-a focused monocular visual field suitable for detecting features e

294 The monocular visual field test (HVF) gave more specific inf

295 visual field constructed from combining the monocular visual fields of each eye.

296 re and after monocular occlusion showed that monocular visual information was used to place the ipsil

297 sion-weighted imaging (DWI) in patients with monocular visual loss of presumed ischemic origin (MVL).

298 near, intermediate and distance compared to monocular visual outcome at the same distances in patien

299 Binocular, compared to monocular, visual processing typically leads to superior

300 s binocular zone is delayed, but only in the monocular zone in GluA1(-/-) mice and only in a backgrou