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1 R, indicate that the transmembrane domain is monomeric.
2 , non-THF solvents, whereas (E)-1 was always monomeric.
3 lysis indicated that both CYP144A1 forms are monomeric.
4 a high-lying pi(B horizontal lineB) orbital, monomeric 16-electron M(II)-diborene (M = Zn, Cd) pi-com
5 aggregated equilibrium component (presumably monomeric 2) was the reactive species, whereas the disol
6 ed and revealed a quantitative conversion of monomeric 3-mercaptopropionic acid to its dimer, dithiod
9 filament length in cardiac muscle by binding monomeric actin and limiting its availability for polyme
11 kinase YopO (YpkA in Yersinia pestis), uses monomeric actin as bait to recruit and phosphorylate hos
12 ation of Rac/Rho family GTPases and by using monomeric actin as bait to recruit and phosphorylate hos
16 he 12-week daily treatment using 2000 UA/day monomeric allergoid sublingual tablets is well tolerated
18 nd in vivo functional assays, that MlaA is a monomeric alpha-helical OM protein that functions as a p
20 eeds, followed by fibril growth during which monomeric alpha-syn molecules sequentially associate wit
22 The transition of intrinsically disordered, monomeric alpha-synuclein into beta-sheet-rich oligomers
23 s positive effects on insulin resistance and monomeric alpha-synuclein load in the striatum, as well
24 ed levels of total and phosphorylated (S129) monomeric alpha-synuclein, evidence of amyloid oligomers
26 bility and this can be phenocopied by adding monomeric alphaS to the cell culture medium of control p
27 ery of exogenous oligomeric alphaSyn but not monomeric alphaSyn was causing a lowering in synapsin-I/
30 Given its multifaceted ability to target monomeric and aggregated Abeta42 species, this candidate
31 inking domains are also highly disordered in monomeric and coacervated ELP3 and form stable helices o
34 ess this question is to genetically engineer monomeric and dimeric CaMKII and evaluate how their acti
36 We propose a model whereby switching between monomeric and dimeric forms allows LIMP-2 to engage dist
38 to its host receptor ephrinB2 and show that monomeric and dimeric receptors activate distinct confor
39 on second harmonic generation, we show that monomeric and dimeric receptors activate distinct confor
42 itive mutants of a variety of proteins, both monomeric and dimeric, and in multiple organisms, namely
43 These results suggest that switching between monomeric and domain-swapped forms may regulate DNA sele
44 ecific balance between the concentrations of monomeric and fibrillar alpha-synuclein that determines
46 ers, while the K101E mutant is predominantly monomeric and K101C/E107C is dominated by oligomers.
48 e WP addition increased the concentration of monomeric and oligomeric flavan-3-ols, and terpenes in t
56 el wherein the degron is exposed when SMN is monomeric and sequestered when SMN forms higher-order mu
58 btained evidence that FliG in the cytosol is monomeric and takes on a more compact conformation, with
59 etermine unspecific binding, proved that the monomeric and the dimeric compound bind to the orthoster
61 valency for various functions, galectin-3 is monomeric, and its functional multivalency therefore is
64 s had more intense, redder colour and higher monomeric anthocyanin content, total phenolic content an
68 (LC-ESI-MS/MS), antioxidant capacity, total monomeric anthocyanin, sugars, and minerals during ripen
69 such as turbidity, pH, acidity, color, total monomeric anthocyanin, total phenolic, and protein conte
70 d chemical (total phenols, total flavonoids, monomeric anthocyanins and ascorbic acid content and ant
71 nificantly (p<0.05) higher concentrations of monomeric anthocyanins and total phenolic compounds than
72 s decreased during ageing, with reduction of monomeric anthocyanins contributing to the formation of
73 in content highlights a lower degradation of monomeric anthocyanins during winemaking with Viniferm P
76 ction (SEP) of 24mg/100g phenolics, 7mg/100g monomeric anthocyanins, 0.1g/100g reducing sugars and 0.
79 elucidate key structural differences between monomeric ApoE3 and ApoE4, which renders ApoE4 thermodyn
80 Structural and biochemical studies of the monomeric archaeal XPD homologues have aided a mechanist
81 nstructs were constitutively active but were monomeric as determined by size-exclusion chromatography
83 trical homodimeric form of SecR decorated by monomeric Atr1a, interacting through lipid-exposed faces
84 anion formed by subsequent lithiation of the monomeric azaaldol adduct, which is characterized as bot
88 h these reactions, a remarkable diversity of monomeric building blocks was achieved by exploiting rea
92 in the dimeric mutant, WT-holoenzyme, and a monomeric CaMKII oligomerization-domain deletion mutant
94 c construct (RapR-Src) led to an increase in monomeric Cav1 in Western blots, as well as a simultaneo
99 g chemical and electrochemical techniques on monomeric cobalt(II) tetra(meso-4-pyridyl)porphyrinate (
102 lpic contribution to the dimerization of the monomeric complex units, large flexible substituents bec
103 hesis that MPH2 is involved in disassembling monomeric complexes during regeneration of dimeric funct
108 ide A cleaved the dimer to the corresponding monomeric cyclic hexapeptide with replacement of Cys by
111 moiety is generated by an unusual, small and monomeric dehydratase, Pac13, which catalyses the dehydr
113 plasmon resonance, as fluorescently labelled monomeric detection reagents in flow cytometry, as pull-
114 BP2 undergoes structural transitions between monomeric, dimeric and oligomeric states visualized by q
115 ng protein and its oligomeric state as being monomeric, dimeric, and/or multimeric, but the native ce
116 experiments are best suited for the study of monomeric, dimerizing, or dimeric proteins but have limi
119 rog.mL(-1)) appears to have no effect on the monomeric enterococcal VanS kinase involved in glycopept
123 Like alphaIIbbeta3 binding to fibrinogen and monomeric fibrin, we found that alphaIIbbeta3 binding to
124 he extractable content and extractability of monomeric flavanols and proanthocyanidins, as well as th
126 in PS and MDBP whereas proanthocyanidins and monomeric flavonoids were found only in PS as identified
127 ion of p33 is unstructured when VacA is in a monomeric form and that it undergoes a conformational ch
129 r step where monomer converts to a different monomeric form that forms on-pathway oligomers and ultim
130 how a ubiquitin ligase maintains an inactive monomeric form that rapidly activates only after asymmet
132 an aptamer which, although developed for the monomeric form, binds also the dimeric form but with a s
135 er removal of scFvs that bind Abeta42 in its monomeric form; (ii) ranking, by surface plasmon resonan
138 ffect depends on protein dimerization, since monomeric Gal-1 fails to stimulate axonal re-growth.
143 of pro-inflammatory transcription factors by monomeric glucocorticoid receptor (GR) has long been vie
145 e A from D. discoideum (DdPoxA) is a stable, monomeric, glycosylated, and secreted heme peroxidase wi
146 that of Env spikes on a virion, whereas its monomeric gp120 exposes many nonneutralizing or strain-s
148 , serum Abs to V2 correlated, whereas in the monomeric gp120 regimen, V2 Abs in rectal secretions, th
150 e recombinant ALVAC vaccine coupled with the monomeric gp120/alum protein have decreased the risk of
151 of anti-gp41 MAbs was superior in targeting monomeric gp41 but was comparable to that seen against t
152 roups of MAbs tested using beads coated with monomeric gp41 or gp120; anti-V2 MAbs were dominant comp
156 howed that NLPs form complexes with terminal monomeric hexose moieties of GIPCs that result in confor
157 s study with tablets containing carbamylated monomeric house dust mite allergoids was to determine th
162 nsfer measurements on biologically relevant, monomeric Httex1 proteins of five different polyQ length
163 purification protocol that generates clean, monomeric Httex1, we identified and mapped three distinc
168 trategies rely on increasing the affinity of monomeric IgG for C1q by introduction of a quadruple mut
169 r domain, respectively, have no influence on monomeric IgG or immune complex binding, but FcRgamma si
170 ic angle spinning solid-state NMR studies of monomeric IL-8 (1-66) bound to full-length and truncated
176 model is structurally incompatible with the monomeric 'initiation' state and is supported by the obs
178 usual in that it is homologous to porins and monomeric instead of trimeric, the typical form of sugar
181 known prefusion conformation to an extended, monomeric intermediate; (ii) reversible trimerization an
184 at -40 degrees C allows the isolation of the monomeric (IPr**)AgH complex, which was crystallographic
185 siloxane) as the hydride donor to afford the monomeric (IPr**)CuH complex, which was spectroscopicall
187 fastest activated response catalysed within monomeric LHC proteins depending on both zeaxanthin and
188 eric light-harvesting complex II (LHCII) and monomeric LHC proteins have been indicated as site(s) of
190 ciation is proposed to potentially alter the monomeric LHCII sensitivity to DeltapH by changing the p
193 etection NMR to generate a model for soluble monomeric medin comprising a stable core of three beta-s
195 ions (A(n+)) in directing the composition of monomeric metal-ligand (ML) complexes that precipitate f
196 loading the electrochemical generation of a monomeric Mn-hydride is suggested to greatly enhance the
197 the absence of the ligand is almost entirely monomeric (molar mass M = 45.7 kDa) in dilute aqueous so
198 ouse myosin VIIa is a slow, high-duty ratio, monomeric motor, this altered hydrolysis rate would redu
199 f fluorescent wild-type SOD1 (wt SOD1YFP) or monomeric mutant G85R SOD1YFP had no effect on net ionic
201 cations disrupt mVP24 dimerization, allowing monomeric mVP24 to bind Kelch with higher affinity and s
204 veal that both the desmethyl and C1-epimeric monomeric nuphar analogous are able to induce rapid apop
206 concentration of total phenols, flavonoids, monomeric, oligomeric and polymeric flavanols, and color
208 s in the relative channel forming ability of monomeric, oligomeric, and fibrillar forms of both Abeta
210 chaperone/alpha-synuclein combinations using monomeric or oligomeric alpha-synuclein (MalphaSyn or Oa
215 macrocyclic beta-sheet peptide results in a monomeric peptide that does not self-assemble to form ol
217 d consistently higher levels of fructose and monomeric phenolic compounds but lower levels of condens
219 on the electron cryomicroscopy structures of monomeric Pol I alone and in complex with Rrn3, undersco
220 e virtually unbreakable, dimerization of the monomeric population was promoted through enzymatic degl
223 poly(allylamine) hydrochloride (PAH) and its monomeric precursor allylamine hydrochloride (AH) with l
224 istinguishable from innocuous aggregates and monomeric precursors, their detection requires measureme
225 cally modifies the phenolic moiety of lignin monomeric precursors, thus preventing their incorporatio
228 ryogenic X-ray structures were solved of the monomeric protease with allosteric inhibitors bound to t
229 Allosteric partial inhibition of soluble, monomeric proteases can offer major regulatory advantage
235 SQ2 polymer, and that the association of the monomeric protein with the RyR2 complex shifts the incre
237 140 (native or uncleaved molecules) or gp120 monomeric proteins elicit relatively poor B-cell respons
238 actable polymeric proteins and unextractable monomeric proteins in flours ranged from 23.83% to 51.97
239 y with mass for these ions and several other monomeric proteins, and the maximum observed charge stat
241 t FLAG-tagged Psb28-2 is present in both the monomeric PSII core complex and a PSII core complex lack
243 cytoplasmic effector Pi04314, expressed as a monomeric red fluorescent protein (mRFP) fusion protein
244 containing synthetic Renilla luciferase and monomeric red fluorescent protein domains, as well as a
246 udies, competing pathways, which involve all monomeric Rh intermediates and a binuclear Rh intermedia
248 igher concentrations, calcium ions stabilize monomeric RsaA, which can then transition to the two-dim
251 bstrates and/or nitrogen sources could alter monomeric saccharide composition and concentrations of t
252 complex to UV-light, photolysis to form the monomeric Sc(2+) complex, [K(crypt)][Sc(NR2)3], was obse
256 ag, and Nef followed by two i.m. boosts with monomeric SIV gp120 or oligomeric SIV gp140 proteins.
257 y SNARE complexes, t-SNARE heterodimers, and monomeric SNAREs, competing with synaptotagmin 1(syt1) f
258 thermore, transgenic mice that overexpressed monomeric sP-selectin did not exhibit increased inflamma
260 r crystal formation, it resulted in strictly monomeric Spa47 that is unable to hydrolyze ATP, despite
261 gth, we could specifically excite either the monomeric species or the fluorescent nanoaggregates.
263 ectron microscopy (EM) and tomography reveal monomeric spikes similar to one of the crystal conformat
264 nal domain is relatively unstructured in the monomeric state but forms an alpha-helix approximately 7
266 N in its assembled RNA-bound state and in a monomeric state, bound to the polymerase cofactor P.
267 sical properties similar to wild-type IL-23 (monomeric state, thermal stability, and secondary struct
268 s Abeta residues 16-26 preferentially in the monomeric state; conversely, crenezumab consistently tar
272 is proposed that is based on the full-length monomeric structure of the protein, on hydrogen-deuteriu
273 theory of domain-swapping from the level of monomeric subunits and multimers to closed spherical she
275 ion, UVPD promoted backbone cleavages of the monomeric subunits, the abundances of which corresponded
278 u inclusions induces the ordered assembly of monomeric Tau, followed by its spreading to distant brai
280 n of the TLR4-MD2 complex, palmitate binds a monomeric TLR4-MD2 complex that triggers endocytosis, RO
281 ed conditions in which Abeta converts from a monomeric to a fibrillar state via a series of kinetical
283 ly part of U(IV) reoxidized, suggesting that monomeric U(IV) might have become incorporated in newly
284 ING or U-box domain of a distinct E3 ligase: monomeric UBE4B, phosphorylated active CBL, or dimeric X
285 n eukaryotes, ubiquitin is encoded both as a monomeric ubiquitin unit fused to a ribosomal gene and a
287 0 degrees , and the two beta-strands of each monomeric unit move apart, to give rise to the well-know
288 rresponding oligomers comprising up to eight monomeric units were studied with respect to their micro
291 ch as the structure-function relationship of monomeric unprocessed proMPO versus the mature dimeric M
292 ormation and monomerisation, indicating that monomeric UVR8 has the potential for UV-B photoreception
293 k region of CD23, and the non-N-glycosylated monomeric version of CD23 was superior in IgE binding co
295 hough sHSPs are characterized by their small monomeric weight, they typically assemble into large pol
296 hat the full-length protein is predominantly monomeric, whereas dimers and trimers are formed to a sm
300 with the tiny (NMR-invisible) population of monomeric (Z)-1 that was formed in a mobile equilibrium
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