ライフサイエンスコーパス: monomorphic

1 covered in 1939, has long been thought to be monomorphic.

2 tes that both gene products are structurally monomorphic.

3 MLH1 exons 9, 11, 14, and 16 were monomorphic.

4 ehydrogenase (Adh) was found to be virtually monomorphic.

5 s in ferritin and HUMPPAPRO were found to be monomorphic.

6 of ventricular arrhythmias in follow-up are monomorphic.

7 polymorphic band, the remaining primers were monomorphic.

8 essfully amplified, the remaining loci being monomorphic.

9 nd polymorphic electrogram to a periodic and monomorphic activity with longer cycle lengths (101 +/-

10 ar "fibrillation-like" activity into regular monomorphic activity.

11 of Ag that are presented by polymorphic and monomorphic Ag-presenting molecules of the immune system

12 changes in pdm3 form sexually dimorphic and monomorphic alleles that segregate within species and ar

13 One-half of the loci were monomorphic among all strains, and overall genetic varia

14 ricular arrhythmias, including 489 that were monomorphic and 13 that were polymorphic.

15 toform, designated 'D,' which is essentially monomorphic and differs by about 27 fixed rearrangements

16 e expected total pedigree branch lengths for monomorphic and dimorphic elements, leading to an estima

17 roadly considered under non-life-threatening monomorphic and life-threatening polymorphic rhythms.

18 ta show that fibrils within this network are monomorphic and most likely represent the thermodynamic

19 These isolate-specific blocks of alternating monomorphic and polymorphic regions imply an exceptional

20 a proteasome branch previously thought to be monomorphic and provide evidence of substantial lineage

21 s associated with renal SOT, occurs late, is monomorphic and retains EBV positivity.

22 We demonstrate that imiquimod induces a monomorphic and self-limited inflammatory response in he

23 The genomes of B. anthracis strains are monomorphic and therefore, typically difficult to distin

24 ents a challenge, since they are genetically monomorphic and traditional molecular techniques have li

25 c biopsy (of which two were re-classified as monomorphic) and one had a low-grade malignant lymphoma.

26 Further, adding a monomorphic anti-HLA-DR antibody substantially inhibited

27 a specialized subset of T lymphocytes with a monomorphic antigen receptor.

28 s, including their genitalia, are remarkably monomorphic, as is their behavior.

29 and that host populations generally will be monomorphic at disease-resistance (R-gene) loci.

30 l they were terminated; the remainder became monomorphic at fhuA between 63 and 303 generations.

31 he fhuA polymorphism, whether polymorphic or monomorphic at the lac operon.

32 species possess a polymorphic X-linked and a monomorphic autosomal color vision gene.

33 posttransplant lymphoma is a rare subtype of monomorphic B-cell posttransplant lymphoproliferative di

34 x and represents one of the most molecularly monomorphic bacteria known.

35 uctural arrangements apparently dictate this monomorphic behavior.

36 ation, are found in the five strains), large monomorphic blocks (i.e., regions where the five strains

37 TbPTP1 inactivation in monomorphic bloodstream trypanosomes by RNA interference

38 of T cells recognize lipids presented by the monomorphic CD1 proteins.

39 es of these cells while their restriction by monomorphic CD1d limits toxicity.

40 diverse glycolipid antigens presented by the monomorphic CD1d molecule.

41 ture (Ti) non-covalently associated with the monomorphic CD3 signaling components.

42 America some 1-2 mya; recently, however, the monomorphic Chr1a has extended into regions of South Ame

43 riod of approximately 10(6) yr, and that the monomorphic Chr1a has swept each population within the p

44 s suggested that chromosome Ia was unusually monomorphic compared with the rest of the genome.

45 onmental strains, Pto, and other genetically monomorphic crop pathogens were inferred to have frequen

46 ed by a monoclonal antibody to a class I HLA monomorphic determinant but not by one specific for HLA

47 anti-human class I MHC mAb that recognizes a monomorphic determinant of the alpha3 domain, profoundly

48 monoclonal antibody, 5H7, is specific for a monomorphic determinant on the a3 domain of human class

49 e factors: poor performance status (3 to 4), monomorphic disease, and graft organ involvement.

50 g EBNA3B leads to aggressive, immune-evading monomorphic DLBCL-like tumors in NOD/SCID/gammac-/- mice

51 variable escape pattern and one had a highly monomorphic escape pattern.

52 o female-biased genes or genes with sexually monomorphic expression patterns.

53 nvergent evolution of sexually dimorphic and monomorphic expression through cis-regulatory changes.

54 atory-raised fish from a population that was monomorphic for all 25 allozyme loci examined (Monkey Sp

55 Four of 13 chemostat cultures monomorphic for the lac operon retained the neutral fhuA

56 n or Japanese samples, in which rs1143679 is monomorphic for the non-risk allele (G).

57 Sri Lankan and introduced material was monomorphic for the same cpDNA haplotype that was absent

58 females have thin dark stripes) or sexually monomorphic for this pigmentation (both sexes show strip

59 In contrast, the sexes were monomorphic for visceral fat (P =.24).

60 present an atomic resolution structure of a monomorphic form of AbetaM01-42 amyloid fibrils derived

61 s, but the evolution of SD from an initially monomorphic genome presents a conundrum.

62 that was abrogated by the addition of a anti-monomorphic HLA class I monoclonal antibody (mAb) (W6/32

63 ze Mtb-derived antigen in the context of the monomorphic HLA-E molecule.

64 Although BCC cells are monomorphic, immunofluorescence microscopy reveals a com

65 Histology was polymorphic in 35 (65%) and monomorphic in 19 (35%).

66 54 months, 79% had kidney SOT, histology was monomorphic in 83% and tumor was EBV+ in 94%.

67 Although 1 SNP was monomorphic in all 3 groups, we observed statistically s

68 are in European Americans (MAF = 0.03%), and monomorphic in Asian populations, suggesting it may be a

69 majority of the human diallelic indels were monomorphic in chimpanzees and gorillas.

70 These SNPs were monomorphic in KR.

71 In contrast, the locus is monomorphic in macaques and orangutans.

72 (Class I) and those previously classified as monomorphic in maize (Class II).

73 e midgut from sexually dimorphic to sexually monomorphic in some species are caused by the loss of CR

74 ma Indians (A allele frequency =0.54) but is monomorphic in the 1000 Genomes European and African pop

75 tions in the larger sample at SNPs that were monomorphic in the corresponding smaller core sample.

76 r (1) polymorphic SNPs in one population but monomorphic in the other, or (2) significant association

77 Forty-four of the 57 cloned Alu repeats were monomorphic in the sample and 13 Alu repeats were dimorp

78 Interestingly, four of the SNPs are monomorphic in the Yoruba population of the HAPMAP proje

79 embryonic pattern of neuroblasts is sexually monomorphic in these animals, we were interested to know

80 sexually dimorphic in other mammals would be monomorphic in this species.

81 was private in any population, 22 SNPs were monomorphic in wildcats and pairwise FCT values revealed

82 ns from the three clonal lineages supports a monomorphic inheritance, which is unique within the geno

83 failures, and rare variants misclassified as monomorphic, is only 1.38% with optiCall, in comparison

84 mal coryzal phase, sudden eruption of fairly monomorphic lesions, and predictable time course with sp

85 infiltrate composed predominantly of small, monomorphic lymphoid cells with scattered plasma cells a

86 that was supported by blocking studies with monomorphic mAbs.

87 muscle fibers expressing the allele-specific monomorphic major histocompatibility complex class I ant

88 r the presence or absence of a given marker, monomorphic markers can be quickly and efficiently mappe

89 MHC-II) molecules as well as the essentially monomorphic MHC class Ib (MHC-Ib) molecules.

90 The primary function of the monomorphic MHC class Ib molecule Qa-1(b) is to present

91 Hence, we provide new insights into how monomorphic MHC molecules interact with T cells.

92 rkers in the Dachshund and find three linked monomorphic microsatellite markers all within a 10-Mb re

93 bacterial or fungal origin presented by the monomorphic MR1 molecule.

94 min B2 biosynthetic pathway presented by the monomorphic MR1 molecule.

95 neration of a signal to the T cell through a monomorphic multicomponent system that includes the CD3

96 his role in adaptive immunity and its highly monomorphic nature in the human population, HLA-E is an

97 The monomorphic nature of HLA-G may allow trophoblast to car

98 Despite the monomorphic nature of sequenced F. tularensis genomes, t

99 revealed 162 nucleotide sites occupied by a monomorphic nucleotide in the human sample but occupied

100 enerate resistant mutants more easily than a monomorphic one.

101 dules (CRM-p and CRM-d) that direct sexually monomorphic or dimorphic Fmo-2 transcription, respective

102 t and consequently whether the population is monomorphic or dimorphic.

103 t "nonclassical" MHC class I (I-b) genes are monomorphic or oligomorphic.

104 gure-8 reentry were inducible, 11 with short monomorphic or polymorphic runs, and 18 lacking inducibl

105 " inducibility definition included sustained monomorphic or polymorphic VT induced with three or fewe

106 e of sex ratio distortion in closely related monomorphic outgroup species suggests that this meiotic

107 In separate screens, monomorphic parasites were exposed to 8-(4-chlorophenylt

108 on real data from six strains of the highly monomorphic pathogen Salmonella Paratyphi A, sequenced i

109 ven after the tachycardia entered the stable monomorphic phase.

110 ferent strategies can evolve in an initially monomorphic population even if mutations have only small

111 pecies is descended from an original, highly monomorphic population following a bottleneck.

112 te disruption of the liver architecture by a monomorphic population of cells of myeloid origin remini

113 The morphologic findings were uniform; a monomorphic population of medium-sized lymphoid cells wi

114 ria revealed the occurrence of a genetically monomorphic population of P. falciparum within a human c

115 evolutionarily stable strategy (ESS), if its monomorphic population rejects the invasion of any other

116 Rather than a monomorphic population strictly determined by Foxp3 as a

117 S:19 strains comprise a clonal, although not monomorphic, population, which is distinct from non-HS:1

118 Using an evolutionary model for monomorphic populations evolving on a fitness landscape,

119 was to assess the role of Purkinje fibers in monomorphic, post-infarction ventricular tachycardia (VT

120 s or male-specific morphogenesis of sexually monomorphic precursors.

121 Monomorphic premature ventricular contractions (PVCs) ha

122 Because the Y. pestis genome is highly monomorphic, previous attempts to characterize the popul

123 C molecules could have evolved originally as monomorphic PRR, presenting pathogen-associated molecula

124 y lesions (n = 1); polymorphic PTLD (n = 1); monomorphic PTLD (n = 27), Hodgkin disease (n = 2).

125 In view of the similarities between monomorphic PTLD and non-Hodgkin's lymphoma in the gener

126 ssion as first-line treatment in adults with monomorphic PTLD is well tolerated and achieves sustaine

127 No cases of monomorphic PTLD were seen.

128 e general population, our policy is to treat monomorphic PTLD with anthracycline-based chemotherapy a

129 localization, invasion of serous membranes, monomorphic PTLD, and T-cell PTLD were independent progn

130 r cases (75%) were categorized as monoclonal monomorphic PTLD.

131 Monomorphic PVCs initiated VF in all 29 identified patie

132 tricular fibrillation in ICM is triggered by monomorphic PVCs originating from the scar border zone w

133 tern of conduction was used for analysis (25 monomorphic reentry episodes, 20 experiments).

134 alysis (experiments in 20 canine hearts with monomorphic reentry).

135 ur simulations give a new prediction for the monomorphic regime of evolution that smaller populations

136 anking noncoding sequences, where completely monomorphic regions may flank highly polymorphic genes.

137 Interactions between CD4 coreceptors and monomorphic regions of MHC class II molecules contribute

138 olateral nucleus (DLN), and for the sexually monomorphic retrodorsolateral nucleus (RDLN).

139 ts (25 canine hearts in which primarily long monomorphic runs of figure-8 reentry were inducible, 11

140 hat dimorphic Wg regulation, in concert with monomorphic segment-specific programmed cell death, are

141 littoralis dickeyi) is genetically the most monomorphic sexually reproducing animal population yet r

142 Dissection of this region in monomorphic slender forms and pleomorphic slender and st

143 , has been widely described as a genetically monomorphic species.

144 imorphic species, but is uniform in sexually monomorphic species.

145 ies-rich islands are inhabited by relatively monomorphic species.

146 hin the two main phylogenetic groups of this monomorphic species.

147 dynamics that drives a population towards a monomorphic state.

148 Further, we demonstrate that such a monomorphic structure is formed within longer sequence c

149 and sequence is indicative of a genomically monomorphic subspecies and explains the inability to dif

150 Monomorphic sustained VT was induced in 35% and 28% of t

151 We consider the baseline case with a monomorphic symbiont and a single diallelic locus in its

152 Due to the rarity of monomorphic T-cell PTLD (T-PTLD), knowledge about pathog

153 rdiac tissue, particularly in the setting of monomorphic tachyarrhythmias.

154 trategies for preventing the transition from monomorphic tachycardia to polymorphic tachycardia and f

155 he ECG, the activity manifested as sustained monomorphic tachycardia.

156 and document the transition from completely monomorphic to classical male-dimorphic populations over

157 leucocephalus nigerrimus), which is sexually monomorphic to the human eye, exhibits sexual dichromati

158 Laboratory-adapted (monomorphic) trypanosome strains respond inefficiently t

159 Monomorphic VA is classified on the basis of site of ori

160 ould be subdivided into 2 variants, namely a monomorphic variant with small maculopapular lesions, wh

161 Clinical observations suggest that the monomorphic variant, if it develops in children, often p

162 women, and after filtering and exclusion of monomorphic variants, 32,827 common (minor allele freque

163 rtion of patients with apparently idiopathic monomorphic VAs of LV origin and are associated with wor

164 ts (65% males; mean age, 44+/-15 years) with monomorphic VAs of LV origin and negative routine diagno

165 e, 40+/-17 years) with apparently idiopathic monomorphic VAs of right ventricular origin served as co

166 identify any abnormality among patients with monomorphic ventricular arrhythmias (VAs) of left ventri

167 Repetitive monomorphic ventricular ectopy (in the absence of sustai

168 ntial causal relationship between repetitive monomorphic ventricular ectopy originating from the righ

169 (11 men; age, 47+/-15 years) with repetitive monomorphic ventricular ectopy, including 8 patients (30

170 d electrical stimulation elicited infrequent monomorphic ventricular tachyarrhythmias (MVT), and domi

171 in those who received their first shock for monomorphic ventricular tachycardia (hazard ratio [HR]:

172 0.028), hemodynamically tolerated sustained monomorphic ventricular tachycardia (HR: 2.19; p = 0.023

173 icular arrhythmias were classified either as monomorphic ventricular tachycardia (MVT) or polymorphic

174 Programmed electric stimulation to induce monomorphic ventricular tachycardia (MVT) was used to as

175 ystole (n=102), organized rhythm (n=120), or monomorphic ventricular tachycardia (n=4).

176 as strongly associated with inducibility for monomorphic ventricular tachycardia (noninducible versus

177 ft ventricular sites of origin of repetitive monomorphic ventricular tachycardia (RMVT).

178 Sudden cardiac death (SCD) and sustained monomorphic ventricular tachycardia (SMVT) are frequentl

179 se 84%; presenting arrhythmia with sustained monomorphic ventricular tachycardia (SMVT) in 68%.

180 inically in 3 forms: 1) paroxysmal sustained monomorphic ventricular tachycardia (SMVT), 2) repetitiv

181 isms of spontaneous termination of sustained monomorphic ventricular tachycardia (SMVT), in the posti

182 The clinical characteristics of sustained monomorphic ventricular tachycardia (SMVT), when it deve

183 The causes of sustained monomorphic ventricular tachycardia (VT) after cardiac v

184 The arrhythmia was rapid monomorphic ventricular tachycardia (VT) in 70% of episo

185 percutaneous catheter ablation of sustained monomorphic ventricular tachycardia (VT) in LMNA cardiom

186 dial tissue can help predict inducibility of monomorphic ventricular tachycardia (VT) in patients wit

187 ) catheter ablation is effective therapy for monomorphic ventricular tachycardia (VT) in patients wit

188 terenol (100 nmol/L) alone induced sustained monomorphic ventricular tachycardia (VT) that originated

189 In catheter ablation of scar-related monomorphic ventricular tachycardia (VT), substrate volt

190 but also provide antitachycardia pacing for monomorphic ventricular tachycardia and antibradycardia

191 ecutive patients with hemodynamically stable monomorphic ventricular tachycardia and coronary artery

192 Patients with sustained monomorphic ventricular tachycardia associated with coro

193 On paired comparison, phase sequences during monomorphic ventricular tachycardia correlated moderatel

194 es were related to inducibility of sustained monomorphic ventricular tachycardia during electrophysio

195 Ventricular stimulation led to sustained monomorphic ventricular tachycardia in 36 patients, nons

196 been useful in guiding catheter ablation of monomorphic ventricular tachycardia in patients with cor

197 target the critical isthmuses for re-entrant monomorphic ventricular tachycardia in tetralogy of Fall

198 presence of a SB led most often to sustained monomorphic ventricular tachycardia rather than to VF, w

199 hospitalization duration, 6-month sustained monomorphic ventricular tachycardia recurrence, quality

200 0% (114 of 184) of patients had no sustained monomorphic ventricular tachycardia recurrence; the prop

201 Notably, recurrent monomorphic ventricular tachycardia requiring >/=2 impla

202 natomical obstacles in the heart and lead to monomorphic ventricular tachycardia that can degenerate

203 total mortality for patients with inducible monomorphic ventricular tachycardia was significantly hi

204 Inducible monomorphic ventricular tachycardia was the most common

205 nimals with reproducibly inducible sustained monomorphic ventricular tachycardia were randomized 2:1:

206 ator was implanted for a positive (inducible monomorphic ventricular tachycardia) but not a negative

207 d the study, 33 patients developed sustained monomorphic ventricular tachycardia, 16 died suddenly, a

208 of ARVC, hemodynamically tolerated sustained monomorphic ventricular tachycardia, and male sex predic

209 VF episode and another developed sustained, monomorphic ventricular tachycardia.

210 rate for initiation of both VF and sustained monomorphic ventricular tachycardia.

211 hich patients would have inducible sustained monomorphic ventricular tachycardia.

212 tricular tachycardia or difficult to control monomorphic ventricular tachycardia.

213 iologic study attempting to induce sustained monomorphic ventricular tachycardia.

214 Genes unique to a monomorphic version of a single parasite chromosome may

215 is associated with the recent emergence of a monomorphic version of Chr1a, which drove a selective ge

216 xception to this geographic segregation is a monomorphic version of one chromosome (Chr1a) that chara

217 The end point was sustained monomorphic VT (cycle length >/=200 ms).

218 t failure in 62%) with recurrent episodes of monomorphic VT (median, 11 in the preceding 6 months) ca

219 r arrhythmias (n = 21), those with inducible monomorphic VT (MVT, n = 18), and those with either indu

220 resented with sustained VT (n=3), repetitive monomorphic VT (n=7), or both (n=4).

221 Both inducible monomorphic VT [relative risk (RR), 5.0; P=0.0002] and p

222 The substrate causing monomorphic VT after infarction is characterized by regi

223 Electroanatomical mapping in patients with monomorphic VT and nonischemic cardiomyopathy typically

224 Sustained monomorphic VT and polymorphic VT were induced in 30.2%

225 eatest in patients presenting with sustained monomorphic VT and those with inducible VT at electrophy

226 treatment with BaCl2 + Caff led to sustained monomorphic VT arising from the NA application site in a

227 first radiofrequency ablation for sustained monomorphic VT associated with structural heart disease

228 Patients in whom monomorphic VT could be induced (ie, inducible patients)

229 lock and converted the bidirectional VT into monomorphic VT in 4 anesthetized RyR2/RyR2(R4496C) mice.

230 Sustained, monomorphic VT in patients with ischemic heart disease i

231 terminated 39 of 69 (59% adjusted) sustained monomorphic VT in the fast VT zone, 509 of 590 (85% adju

232 The first presentation of sustained monomorphic VT in the recovery period after CABG is unco

233 ced in 203 patients (EPS negative, group 1), monomorphic VT induced in 87 patients, consisting of ver

234 ugh the prognostic significance of inducible monomorphic VT is known, the significance of inducible V

235 (4) Monomorphic VT lasting 1.36 +/- 0.2 s in 5 out of 5 KCNE

236 81 consecutive patients with post-infarction monomorphic VT referred for catheter ablation, 9 patient

237 Monomorphic VT was clearly unifocal, whereas bidirection

238 Sustained, monomorphic VT was induced by programmed stimulation.

239 Despite this protection from VF, monomorphic VT was induced with propafenone in 57% of bu

240 re ventricular contractions, or nonsustained monomorphic VT was induced.

241 Sustained monomorphic VT was inducible in 53 (45%) patients; in 20

242 Sustained monomorphic VT was inducible in 7 of 11 animals.

243 weeks after myocardial infarction, sustained monomorphic VT was reproducibly induced in all animals (

244 patients with nonischemic cardiomyopathy and monomorphic VT with an average of 178+/-83 sites per cha

245 pared a narrow inducibility definition (only monomorphic VT) and a broad definition (standard definit

246 Complete success (noninducibility of any monomorphic VT) was achieved in 17 patients (38%), parti

247 ion of 702 episodes, including 669 sustained monomorphic VT, 20 polymorphic VT, 10 supraventricular t

248 h a single biphasic shock for ATP-refractory monomorphic VT, and represents a novel electrotherapy to

249 Epicardial mapping showed that monomorphic VT, bidirectional VT, and polymorphic VT man

250 Relationships between inducibility of monomorphic VT, peak Ecc, and time to peak Ecc were anal

251 Propafenone promotes slow monomorphic VT, probably by use-dependent conduction slo

252 try circuit in patients with post-infarction monomorphic VT, resulting in a type of VT with a relativ

253 Unlike monomorphic VT, these arrhythmic syndromes are associate

254 brillation episode, or a recorded, sustained monomorphic VT.

255 The majority of these episodes were monomorphic VT.

256 uli, appears less relevant than induction of monomorphic VT.

257 tion (ICD shocks) in patients with inducible monomorphic VT.

258 Data from catheter mapping of 70 monomorphic VTs in 36 patients with prior myocardial inf

259 cy catheter ablation targeting all inducible monomorphic VTs that allowed mapping was performed in 52

260 A total of 56 monomorphic VTs were induced (3.8+/-2.1 per animal).

261 All inducible monomorphic VTs with a rate approximating or slower than

262 Furthermore, when targeting all inducible monomorphic VTs, complete procedural success was achieve

263 ients with multiple hemodynamically unstable monomorphic VTs.

264 , genotypes of 185,119 variants (11,356 were monomorphic) were compared in 530 individuals that had w

265 The etiology of sustained monomorphic wide QRS complex tachycardia is often uncert

266 Brucella species are highly monomorphic, with minimal genetic variation among specie

267 Loci that are monomorphic within A or D genome types, but polymorphic

268 d a handful of protein-coding genes that are monomorphic within species.