ライフサイエンスコーパス: mononucleotide

1 milk was the richest source of nicotinamide mononucleotide.

2 res an unprecedented binding site for flavin mononucleotide.

3 a result that was reversed with nicotinamide mononucleotide.

4 s: anthraquinone-2,6-disulphonate and flavin mononucleotide.

5 g coupled to binding of its cofactor, flavin mononucleotide.

6 ectrolyte based on the sodium salt of flavin mononucleotide.

7 instead convert nicotinamide to nicotinamide mononucleotide.

8 nt to enhance the water solubility of flavin mononucleotide.

9 tivity and of the NAMPT product nicotinamide mononucleotide.

10 esponsible for dephosphorylation of pyridine mononucleotides.

11 e remaining complementary single strand into mononucleotides.

12 thesis termination by DNA polymerases within mononucleotides.

13 catalyzes dephosphorylation of pyrimidine 5'-mononucleotides.

14 erative manner and with lower affinity, like mononucleotides.

15 oxidases, this enzyme contains haem, flavin mononucleotide, 2Fe-2S and tetrahydrofolic acid cofactor

16 hat three yeast enzymes possess nicotinamide mononucleotide 5'-nucleotidase activity in vitro.

17 mutant P4 enzyme complexed with nicotinamide mononucleotide, 5'-AMP, 3'-AMP, and 2'-AMP.

18 Listeria genomes lack CobT, the nicotinamide mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphori

19 er ([4Fe-4S](2+)) and a 6-S-cysteinyl flavin mononucleotide (6-S-Cys-FMN) as redox cofactors.

20 Here we show that the flavin mononucleotide, a common redox cofactor, wraps around si

21 ting potential-induced changes in the flavin mononucleotide active site of a flavoenzyme.

22 They are comprised of two mononucleotides, adenosine monophosphate and nicotinamid

23 w: the NAD+ biosynthetic enzyme nicotinamide mononucleotide adenyltransferase (Nmnat), which acts in

24 in the first intron of Nmnat2 (Nicotinamide mononucleotide adenyltransferase 2).

25 mutant mice by expression of an nicotinamide mononucleotide adenylyl transferase 1 (Nmnat-1)/truncate

26 ld(S)) encodes a chimeric Ube4b/nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1) fusion pr

27 of the NAD synthesizing enzyme nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1) has been

28 de (NAD(+)) biosynthetic enzyme nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1).

29 inucleotide-synthesizing enzyme nicotinamide mononucleotide adenylyl transferase 1.

30 Nicotinamide mononucleotide adenylyl transferase 2 (NMNAT2) is a key

31 Nicotinamide mononucleotide adenylyl transferase 2 (NMNAT2) is neurop

32 nce and protective function for nicotinamide mononucleotide adenylyl transferases (NMNATs).

33 Flavin mononucleotide adenylyltransferase (FMNAT) catalyzes the

34 the last steps of NAD biogenesis, nicotinate mononucleotide adenylyltransferase (NadD) and NAD synthe

35 Bacterial nicotinic acid mononucleotide adenylyltransferase (NaMNAT; EC 2.7.7.18)

36 This reaction is catalyzed by nicotinate mononucleotide adenylyltransferase (NMAT), which is esse

37 reased levels of nicotinamide/nicotinic acid mononucleotide adenylyltransferase (NMNAT) act as a powe

38 tective effects of NAD synthase nicotinamide mononucleotide adenylyltransferase (NMNAT) against activ

39 ies on the NAD synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT) have uncovere

40 Nicotinamide mononucleotide adenylyltransferase (NMNAT) is a conserve

41 Overexpression of nicotinamide mononucleotide adenylyltransferase (Nmnat), a component

42 otective function of Wld(S) and nicotinamide mononucleotide adenylyltransferase (Nmnat).

43 indicates that it is a putative nicotinamide mononucleotide adenylyltransferase (NMNAT).

44 nuclear NAD(+) synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) is frequentl

45 leotide (NAD) synthetic enzyme, nicotinamide mononucleotide adenylyltransferase (Nmnat1).

46 oribosyltransferase (NAMPT) and nicotinamide mononucleotide adenylyltransferase 1 (NMNAT-1) constitut

47 nstrated that overexpression of nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1) or exogeno

48 full-length coding sequence of nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1), which alo

49 The NAD-synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) is a criti

50 A and protein levels of NMNAT2 (nicotinamide mononucleotide adenylyltransferase 2), a recently identi

51 Bacterial nicotinate mononucleotide adenylyltransferase encoded by the essent

52 NAD(+), the metabolite of WldS/nicotinamide mononucleotide adenylyltransferase enzymatic activity, i

53 Nicotinate mononucleotide adenylyltransferase NadD is an essential

54 uding inhibition by both NMNAT (nicotinamide mononucleotide adenylyltransferase) expression and loss

55 encodes the nuclear isoform of nicotinamide mononucleotide adenylyltransferase, a rate-limiting enzy

56 Nicotinamide mononucleotide adenylytransferase (NMNAT) is a neuroprot

57 trations of 3MI and 6MI in solution with the mononucleotides AMP, CMP, GMP, and TMP.

58 as minimized by the addition of nicotinamide mononucleotide, an inhibitor of NAD(+) glycohydrolases.

59 adenylyl transferase condenses nicotinamide mononucleotide and (tz) ATP to yield N(tz) AD(+) , which

60 The hydrophilic matrix arm comprises flavin mononucleotide and 8 iron-sulfur clusters involved in el

61 on analysis (NCA) method was used to compare mononucleotide and dinucleotide frequencies for RNA viru

62 examine these interactions, including simple mononucleotide and dinucleotide position weight matrix m

63 High levels of MSI at mononucleotide and dinucleotide repeats in colorectal ca

64 edox cofactors: a noncovalently bound flavin mononucleotide and eight iron-sulfur clusters.

65 the precursor of the flavin coenzymes flavin mononucleotide and flavin adenine dinucleotide.

66 ough its conversion to coenzyme forms flavin mononucleotide and flavin adenine dinucleotide.

67 roduction in the mitochondria include flavin mononucleotide and flavin mononucleotide-binding domain

68 or voltage (LOV) domains, which bind flavin mononucleotide and form a covalent adduct between a cons

69 ation of nicotinamide riboside, nicotinamide mononucleotide and NAD in milk by means of a fluorometri

70 tion with the NAD(+) precursors nicotinamide mononucleotide and nicotinamide riboside also increases

71 The NAD biosynthetic precursors nicotinamide mononucleotide and nicotinamide riboside are reported to

72 osphorylate the mononucleotides nicotinamide mononucleotide and nicotinic acid mononucleotide (NAMN)

73 deamidation steps leading to nicotinic acid mononucleotide and nicotinic acid riboside production ar

74 The photosensor YtvA binds flavin mononucleotide and regulates the general stress reaction

75 entric pi-pi interactions between the flavin mononucleotide and the underlying graphene wall.

76 lity (MSI) analysis using 5 highly sensitive mononucleotides and 2 pentanucleotides was performed.

77 xoribonuclease on some substrates, releasing mononucleotides and a ladder of digestion products.

78 ively digests the 5'-ended strand to form 5' mononucleotides and a long 3' overhang.

79 d efficient enzymes that hydrolyze RNA to 3' mononucleotides and also possess antitumorigenic and ant

80 In order to study condensation products of mononucleotides and hydrolysis of their polymers, we est

81 Chargaff's second parity rules for mononucleotides and oligonucleotides (CIImono and CIIoli

82 which demonstrates that low-molecular-weight mononucleotides and simple cationic peptides spontaneous

83 es, adenosine monophosphate and nicotinamide mononucleotide, and are present as oxidized and reduced

84 rent subunits, a non-covalently bound flavin mononucleotide, and eight iron-sulfur clusters.

85 nicotinic acid mononucleotide, nicotinamide mononucleotide, and NmR, can also delay axonal degenerat

86 If 5'-mononucleotides are in solution at millimolar concentrat

87 eotide, thus enabling discrimination against mononucleotides as substrates.

88 significantly higher affinity of the flavin mononucleotide assembly for (8,6)-single-walled carbon n

89 In the presence of a surfactant, the flavin mononucleotide assembly is disrupted and replaced withou

90 The strength of the helical flavin mononucleotide assembly is strongly dependent on nanotub

91 he second method analyzes nuclease-generated mononucleotides before and after treatment with base or

92 e change (R116Q), predicted to affect flavin mononucleotide binding and binding of the two PNPO dimer

93 e intermediate and, together with the flavin mononucleotide binding cradle, we propose a novel cataly

94 We have defined a novel flavin mononucleotide binding cradle, which is a recurrent moti

95 For tight and specific binding to the eIF4E mononucleotide binding site, there seems to be a clear r

96 ng interaction between the cap and the eIF4E mononucleotide binding site.

97 This correlated with loss of flavin mononucleotide binding.

98 gene XC_0249 encodes a protein with a cyclic mononucleotide-binding (cNMP) domain and a GGDEF diguany

99 a bacterial monooxygenase, contains a flavin mononucleotide-binding domain bearing a strong structura

100 ria include flavin mononucleotide and flavin mononucleotide-binding domain of complex I, ubisemiquino

101 Using flavin mononucleotide-binding proteins and glycosidases as exam

102 lly tight binding pocket accommodates flavin mononucleotide but not NAD(P)H.

103 precursor that is converted to nicotinamide mononucleotide by specific nicotinamide riboside kinases

104 red in equimolar mixtures of the constituent mononucleotides by one to two orders of magnitude, indic

105 Furthermore, if the mononucleotides can form complementary base pairs, then

106 eaction to form the NAD precursor nicotinate mononucleotide, carbon dioxide, and pyrophosphate from q

107 Per-Arnt-Sim (PAS) family, contains a flavin mononucleotide chromophore that forms a covalent bond wi

108 between a conserved cysteine and the flavin mononucleotide chromophore upon photoexcitation.

109 entation and contraction of the bound flavin mononucleotide cofactor and cleavage of the ribityl tail

110 pong type mechanism, catalyzed by the flavin mononucleotide cofactor in the active site for NADH oxid

111 d proteins, iron-sulfur clusters, and flavin mononucleotide cofactor require the participation of ass

112 rotonated and deprotonated forms of the four mononucleotides dAMP, dCMP, dGMP, and dTMP was studied e

113 e C-terminal domain harbors the nicotinamide mononucleotide deamidase activity, and the structure of

114 CinA was shown to have both nicotinamide mononucleotide deamidase and ADP-ribose pyrophosphatase

115 tionships of the functionally diverse flavin mononucleotide-dependent nitroreductase (NTR) superfamil

116 A nicotinic acid mononucleotide derivative is tethered to Lys(184) and fo

117 tes at reporter cassettes containing defined mononucleotide, dinucleotide, and tetranucleotide micros

118 ts (STRs) with individual motifs composed of mononucleotides, dinucleotides or higher including hexam

119 any cofactors of enzymatic processes such as mononucleotides (e.g. ADP, ATP, GTP), dinucleotide cofac

120 ding a methylene blue-labeled electro-active mononucleotide (eNT).

121 The most frequent mutation, a mononucleotide expansion from a polyA repeat tract (c.13

122 that an aliphatic (dodecyl) analog of flavin mononucleotide, FC12, leads to high dispersion of SWNTs,

123 e MtrC from Shewanella oneidensis and flavin mononucleotide (FMN in fully oxidized quinone form) usin

124 contain a distinctive non-heme diiron/flavin mononucleotide (FMN) active site.

125 egulated (LOV1 and LOV2) domains bind flavin mononucleotide (FMN) and activate the phototropism photo

126 lular metabolism through formation of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FA

127 avin (vitamin B2) is the precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide, wh

128 flavin-dependent enzyme that converts flavin mononucleotide (FMN) and glutamate to 8-amino-FMN via th

129 ne biosynthesis pathway and harbors a flavin mononucleotide (FMN) as a potential cofactor.

130 which contains a non-covalently bound flavin mononucleotide (FMN) as cofactor, acquires its native al

131 ure of V. harveyi luciferase bound to flavin mononucleotide (FMN) at 2.3 A.

132 own to involve formation of a triplet flavin mononucleotide (FMN) chromophore followed by the appeara

133 teine residue and an internally bound flavin mononucleotide (FMN) chromophore.

134 constraints in the environment of the flavin mononucleotide (FMN) chromophore; in iLOV, the methyl gr

135 urprisingly, IDI-2 requires a reduced flavin mononucleotide (FMN) coenzyme to carry out this redox ne

136 R) where the protein and/or intrinsic flavin mononucleotide (FMN) cofactor are isotopically labeled w

137 lent attachment of an analogue of the flavin mononucleotide (FMN) cofactor onto carboxylic functional

138 diiron-carboxylate site proximal to a flavin mononucleotide (FMN) cofactor.

139 mmediately after turnover with NO are flavin mononucleotide (FMN) dependent, implicating an additiona

140 The redox potential of the flavin mononucleotide (FMN) hydroquinones for one-electron redu

141 to a large increase in the amount of flavin mononucleotide (FMN) in the E. coli cell extract.

142 e chiral D-ribityl phosphate chain of flavin mononucleotide (FMN) induces a right-handed helix that e

143 ween electrostatic plus van der Waals flavin mononucleotide (FMN) interdigitation and H-bonding inter

144 Flavin mononucleotide (FMN) is a coenzyme for numerous proteins

145 o the flavodoxin superfamily in which flavin mononucleotide (FMN) is firmly anchored to the protein.

146 active site with two adjacently bound flavin mononucleotide (FMN) ligands, one deeply buried and tigh

147 plant-type [2Fe-2S] cluster, and one flavin mononucleotide (FMN) per enzyme.

148 c hydrocarbons by a phosphate-bearing flavin mononucleotide (FMN) photocatalyst on high surface area

149 The flavin mononucleotide (FMN) quinones in flavodoxin have two cha

150 e of the disulfide in the presence of flavin mononucleotide (FMN) resulted in the reversible formatio

151 etween Cys450 and the C4a atom of the flavin mononucleotide (FMN) results in local rearrangement of t

152 Flavin mononucleotide (FMN) riboswitches are genetic elements,

153 The flavin mononucleotide (FMN) serves as the one-electron donor to

154 The IET from the flavin mononucleotide (FMN) to heme domains is essential in the

155 erdomain electron transfer (IET) from flavin mononucleotide (FMN) to heme is essential in nitric oxid

156 aprotein electron transfer (IET) from flavin mononucleotide (FMN) to heme is essential in nitric oxid

157 no acid, additional members of a rare flavin mononucleotide (FMN) variant class, and also variants of

158 phate (PLP), folate, vitamin B12, and flavin mononucleotide (FMN) were measured for all subjects.

159 ity capable of reducing either FAD or flavin mononucleotide (FMN) with NADH as the reductant.

160 DH, the primary acceptor of electrons flavin mononucleotide (FMN), and a chain of seven iron-sulfur c

161 flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), are two key cofactors involved in

162 ons flavins, including riboflavin and flavin mononucleotide (FMN), into the surrounding medium to act

163 at residue T236, the binding site for flavin mononucleotide (FMN), resides in the cytoplasm.

164 flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), the physiologically relevant catal

165 is oxidized by a noncovalently bound flavin mononucleotide (FMN), then seven iron-sulfur clusters tr

166 V2 protein that binds the chromophore flavin mononucleotide (FMN), we have developed a promising phot

167 for NO production is a complex of the flavin mononucleotide (FMN)-binding domain and the heme domain,

168 hemical characterization of UbiX as a flavin mononucleotide (FMN)-binding protein, no decarboxylase a

169 he Acg family turns out to be unusual flavin mononucleotide (FMN)-binding proteins that have probably

170 Prior evidence indicated the flavin mononucleotide (FMN)-binding riboswitch aptamer adopted

171 analysis revealed the presence of one flavin mononucleotide (FMN)-binding site and two iron-sulfur cl

172 associated negative regulators by its flavin mononucleotide (FMN)-containing light-oxygen-voltage dom

173 yl diphosphate isomerase (IDI-2) is a flavin mononucleotide (FMN)-dependent enzyme that catalyzes the

174 sts that BluB is a member of the NADH/flavin mononucleotide (FMN)-dependent nitroreductase family, an

175 of unknown function, and a paucity of flavin mononucleotide (FMN)-dependent proteins in these familie

176 Flavin mononucleotide (FMN)-specific riboswitches, also known a

177 d one molecule of noncovalently bound flavin mononucleotide (FMN).

178 o have decreased affinity for reduced flavin mononucleotide (FMNH(2)).

179 ecifically interacts with the reduced flavin mononucleotide (FMNH2) and that FMNH2 can quickly reduce

180 The reduced flavin mononucleotide (FMNH2) generated by FRP must be supplied

181 oop are governed by binding of either flavin mononucleotide (FMNH2) or polyvalent anions.

182 .0, 7.0) containing a reduced form of flavin mononucleotide (FMNH2, 100 muM), a biogenic soluble elec

183 st and catalyzes the formation of nicotinate mononucleotide from quinolinate and 5-phosphoribosyl-1-p

184 riminatory short sequence repeat loci, i.e., mononucleotide G and trinucleotide GGT, in isolates from

185 en the nucleotide and the active-site flavin mononucleotide have complementary oxidation states, and

186 B3, and its phosphorylated form nicotinamide mononucleotide, have been shown to be potent supplements

187 he redox reaction kinetics of reduced flavin mononucleotide (i.e., FMNH(2)) and reduced riboflavin (i

188 e DNA sequencing strategies that employ free mononucleotide identification.

189 Alternatively, NADH oxidation, by the flavin mononucleotide in complex I, can be coupled to the reduc

190 nicotinamide adenine dinucleotide to flavin mononucleotide in morphinone reductase proceeds via envi

191 e that converts nicotinamide to nicotinamide mononucleotide in the NAD biosynthetic pathway from nico

192 , triggering the digestion of the probe into mononucleotides including a methylene blue-labeled elect

193 for residues near the surface of the flavin mononucleotide, including 87-90 (loop 1), and for key CY

194 ain; it comprises NADH oxidation by a flavin mononucleotide, intramolecular electron transfer along a

195 ic organisms, and its requirement for flavin mononucleotide is even more uncommon in catalysis.

196 During catalysis, NADH oxidation by a flavin mononucleotide is followed by electron transfer to a cha

197 The primary electron acceptor, flavin-mononucleotide, is within electron transfer distance of

198 Selection is detectable even at the mononucleotide level, so that the asymmetric base compos

199 ate experimentally that both the length of a mononucleotide microsatellite and its sequence context i

200 on start site density, H3K4me1 coverage, and mononucleotide microsatellite coverage are significant p

201 ion-deletion (indel) rates observed in short mononucleotide microsatellites (here referred to as poly

202 Fourth, mutability of mononucleotide microsatellites is impacted by their loca

203 rectal cancers revealed indels at 54 million mononucleotide microsatellites of three or more nucleoti

204 c background mutation rate in protein-coding mononucleotide microsatellites, allowing a full catalogi

205 ains modulate ROS production from the flavin mononucleotide moiety and iron-sulfur clusters.

206 c light scattering and to contain one flavin mononucleotide molecule per monomer.

207 ce repeats, the most abundant (47.8 %) being mononucleotide motifs.

208 ed neuronal maintenance factor, nicotinamide mononucleotide (NAD) adenylyl transferase (NMNAT), a pro

209 onds to depletion of cellular nicotinic acid mononucleotide (NaMN) and mediates nicotinamide mononucl

210 cotinamide mononucleotide and nicotinic acid mononucleotide (NAMN) and thus catalyze NR and NAR forma

211 ase (QAPRTase, EC 2.4.2.19) forms nicotinate mononucleotide (NAMN) from quinolinic acid (QA) and 5-ph

212 lyze the adenylylation of the nicotinic acid mononucleotide (NaMN) precursor to nicotinic acid dinucl

213 f an adenylyl group of ATP to nicotinic acid mononucleotide (NaMN) to form nicotinic acid dinucleotid

214 sfers the phosphoribosyl group of nicotinate mononucleotide (NaMN) to phenol or p-cresol, yielding al

215 t the point where the reaction of nicotinate mononucleotide (NaMN) with ATP is coupled to the formati

216 NadD substrates, i.e. ATP and nicotinic acid mononucleotide (NaMN).

217 robes, alpha-RP is synthesized by nicotinate mononucleotide (NaMN):DMB phosphoribosyltransferases (Co

218 A redox flow battery using flavin mononucleotide negative and ferrocyanide positive electr

219 -III, but not CN-IA, can dephosphorylate the mononucleotides nicotinamide mononucleotide and nicotini

220 s of these enzymes, including nicotinic acid mononucleotide, nicotinamide mononucleotide, and NmR, ca

221 inic acid adenine dinucleotide, nicotinamide mononucleotide, nicotinic acid, or nicotinamide.

222 Nicotinamide mononucleotide (NMN) adenylyltransferase 2 (Nmnat2) cata

223 zes the reversible synthesis of nicotinamide mononucleotide (NMN) and inorganic pyrophosphate (PP i)

224 uding striking accumulations of nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) in t

225 ar NAD(+) or NAD(+) precursors, nicotinamide mononucleotide (NMN) and NR, can reverse the FK866-induc

226 obtain pyridine from exogenous nicotinamide mononucleotide (NMN) by three routes.

227 hown that the NAD(+) precursor, nicotinamide mononucleotide (NMN) can reverse some of the negative co

228 onucleotide (NaMN) and mediates nicotinamide mononucleotide (NMN) catabolism, thereby contributing to

229 cture for pyrophosphorolysis of nicotinamide mononucleotide (NMN) from kinetic isotope effects (KIEs)

230 expression of bacterial nicotinamide adenine mononucleotide (NMN) in zebrafish and mice, which decrea

231 mice with the NAD(+) precursor nicotinamide mononucleotide (NMN) increases BubR1 abundance in vivo.

232 nicotinamide nucleoside of the nicotinamide mononucleotide (NMN) leaving group are oriented solely v

233 route, the amidation of NaMN to nicotinamide mononucleotide (NMN) occurs before the adenylylation rea

234 with NAD(+) precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), prot

235 by the Nampt enzymatic product nicotinamide mononucleotide (NMN), was not blocked by the Nampt enzym

236 mpensated for by an alternative nicotinamide mononucleotide (NMN)-preferring adenylyltransferase (slr

237 mR, converting it internally to nicotinamide mononucleotide (NMN).

238 acterially expressed LOV domains bind flavin mononucleotide noncovalently and are photochemically act

239 ns studied on average than in the individual mononucleotides of G and C.

240 se the templated polymerization of activated mononucleotides of the opposite handedness.

241 was identified, which was mutated by either mononucleotide or dinucleotide adenosine deletions in 64

242 (millimolar) concentrations of nicotinamide mononucleotide or NAMN for efficient catalysis.

243 Under a neutral evolution model, each mononucleotide or oligonucleotide should have a symmetri

244 affected residues involved in binding flavin mononucleotide or pyridoxal 5'-phosphate and many of the

245 formation of long nucleic acid polymers from mononucleotides or short oligonucleotides remains elusiv

246 We previously reported that 5'-mononucleotides organized within a multilamellar lipid m

247 peed the reversal of formaldehyde adducts of mononucleotides over standard buffers.

248 ategy using common dimethoxytrityl-protected mononucleotide phosphoramidites and a single orthogonall

249 og of E. coli gene nadD, is a nicotinic acid mononucleotide-preferring adenylyltransferase.

250 phatic acids and utilize a prenylated flavin mononucleotide (prFMN) as cofactor, bound adjacent to a

251 newly identified cofactor, prenylated flavin mononucleotide (prFMN).

252 emplate-directed polymerization of activated mononucleotides proceeds readily in a homochiral system,

253 ing event to single-strand DNA, and releases mononucleotide products.

254 degrees 1 values for the protonated cationic mononucleotides ranged from -10.5 to -13.5 kcal mol-1 wi

255 Flavins (riboflavin and flavin mononucleotide) recently have been shown to be excreted

256 frequent frameshift mutations in the coding mononucleotide repeat of TFAM in sporadic colorectal can

257 ellite stabilization was largely confined to mononucleotide repeat sequences.

258 pe-specific transcription of an out-of-frame mononucleotide repeat that is placed between a translati

259 he DNA damage response gene ATR (exon 10 A10 mononucleotide repeat) have been previously described in

260 pa) inserts dGMP and dCMP within the [T](11) mononucleotide repeat, producing an interrupted 12-bp al

261 ze sequence context-dependent mutagenesis at mononucleotide repeats (A-tracts and G-tracts) in human

262 reveals diverse-length polymorphisms in long mononucleotide repeats (microsatellites) in several sero

263 Mononucleotide repeats (MNRs) are abundant in eukaryotic

264 Mononucleotide repeats interrupt contig assembly with in

265 ld increase in small nucleotide deletions at mononucleotide repeats over control B6, which are a sign

266 Here we examine the positions of mononucleotide repeats within microbial genes and detect

267 nstability, more marked at dinucleotide than mononucleotide repeats.

268 n, utilization of extracellular nicotinamide mononucleotide requires prior conversion to NmR mediated

269 tidine (C), guanosine (G), and thymidine (T) mononucleotides, respectively.

270 The NAD(+) precursor nicotinamide mononucleotide restored the cellular NAD(+)/NADH ratio a

271 th electron shuttle molecules such as flavin mononucleotide, resulting in the formation of high-molec

272 An artificial flavin mononucleotide riboswitch and a randomly generated RNA s

273 Using experimental data for flavin mononucleotide riboswitch as a guide, we show that effic

274 y replacing alternative diSSRs, by replacing mononucleotide-rich tracts and, in fewer cases, by expan

275 To address this issue, we removed all mononucleotide runs >3N from the yeast lys2DeltaBgl and

276 ne typically occur in simple repeats such as mononucleotide runs and are thought to reflect spontaneo

277 length threshold for polymerase slippage in mononucleotide runs is 4N.

278 transfer, render specific nucleotides along mononucleotide runs susceptible to base modification, wh

279 ding sequences and in short rather than long mononucleotides runs.

280 enterica serovar Typhimurium and the flavin mononucleotide-sensing ribB riboswitch from Escherichia

281 ifetime measurements of the intrinsic flavin mononucleotide show marked differences between "light" a

282 The syntheses of the BPQ-3'-mononucleotide standards were carried out in a manner si

283 city toward both nicotinate and nicotinamide mononucleotide substrates, which is consistent with its

284 ure of a complex with the product nicotinate mononucleotide suggests a mechanism for deamidation.

285 A range of commercially available 5'-mononucleotide supplemented infant formulas and three hu

286 Here, we report that a mononucleotide (T/U)16 tract located in the 3' untransla

287 ey interactions involving their bound flavin mononucleotide that suggest a unique catalytic behavior

288 icotinamide, nicotinic acid, or nicotinamide mononucleotide, the Ca(2+) content of thapsigargin-sensi

289 on pathway by dephosphorylating nicotinamide mononucleotide to nicotinamide riboside.

290 It contains a flavin mononucleotide to oxidize NADH, and an unusually long se

291 It contains a flavin mononucleotide to oxidize NADH, and eight iron-sulfur cl

292 e responsible for catalyzing the addition of mononucleotides to a growing polymer using a DNA or RNA

293 We use a biological cofactor, flavin mononucleotide, to demonstrate the power of synchrotron

294 ynthetic mimic of the natural ligand, flavin mononucleotide, to repress riboswitch-mediated ribB gene

295 diffusivity between an oligonucleotide and a mononucleotide toward a negatively charged ITO electrode

296 active Cre recombinase transgene with a long mononucleotide tract altering the reading frame was stoc

297 llow for an unstable genetic feature, a long mononucleotide tract, in an essential gene.

298 dertaken for the preconcentration of five 5'-mononucleotides using the hollow fibers.

299 Simulations of deprotonated mononucleotides with four water molecules yielded a larg

300 Analogues of oligonucleotides and mononucleotides with hydrophobic and/or cationic phophot