ライフサイエンスコーパス: monosodium urate

1 e physiological consequences of crystallized monosodium urate acutely causing liver/kidney damage or

2 ion in response to double-stranded RNA, ATP, monosodium urate, adjuvant aluminium, rotenone, live Esc

3 y response to intraperitoneal challenge with monosodium urate and the development of experimental aut

4 e understanding of the cellular responses to monosodium urate, calcium pyrophosphate dihydrate and ba

5 we report that crystals of calcium oxalate, monosodium urate, calcium pyrophosphate dihydrate and cy

6 e and humans involved in the pathogenesis of monosodium urate, calcium pyrophosphate dihydrate and hy

7 In addition to monosodium urate, calcium pyrophosphate dihydrate, and a

8 accumulation of metabolic substrates such as monosodium urate, ceramide, cholesterol, and glucose can

9 NLRP3-dependent neutrophil recruitment in a monosodium urate crystal inflammatory murine peritonitis

10 Analogously, monosodium urate crystal-induced neutrophil migration to

11 sinic-polycytidylic acid or a combination of monosodium urate crystals and Mycobacterium smegmatis wa

12 her complement-activating structures such as monosodium urate crystals and zymosan was not affected b

13 imal tubule and the inflammatory response to monosodium urate crystals are translating into potential

14 atory arthritis, caused by the deposition of monosodium urate crystals in and around the joints.

15 ry arthritis that results from deposition of monosodium urate crystals in the joint.

16 However, tophi and tissue stores of monosodium urate crystals resolve slowly, particularly i

17 eta-driven inflammation, NLRP3 activation by monosodium urate crystals similarly increased IL-6.

18 Monosodium urate crystals stimulate IL-1beta secretion v

19 In a mouse peritonitis model of gout, using monosodium urate crystals to activate NLRP3, 15d-PGJ2 ca

20 In contrast, LPS, monosodium urate crystals, or M. smegmatis alone had no

21 ntiproteases was also observed in a model of monosodium urate crystals-induced inflammation.

22 Monosodium urate enhanced CD86 and OX40L expression on D

23 ted IL-1beta normally in response to ATP and monosodium urate, indicating that caspase-11 is engaged

24 ed Pyk2/FAK dual inhibitor PF-562271 reduced monosodium urate-mediated peritonitis, a disease model u

25 Monosodium urate monohydrate (MSU) and calcium pyrophosp

26 recognition of dormant articular and bursal monosodium urate monohydrate (MSU) crystal deposits, the

27 ruitment of polymorphonuclear cells (PMN) in monosodium urate monohydrate (MSU) crystal-induced infla

28 Although monosodium urate monohydrate (MSU) crystals have been re

29 Monosodium urate monohydrate (MSU) crystals have remarka

30 The mechanism by which monosodium urate monohydrate (MSU) crystals intracellula

31 Articular deposition of monosodium urate monohydrate (MSU) crystals may promote

32 Monosodium urate monohydrate (MSU) crystals promote gout

33 Monosodium urate monohydrate (MSU) crystals were adminis

34 ete proinflammatory cytokines in response to monosodium urate monohydrate (MSU) crystals.

35 e of mononuclear phagocytes to the uptake of monosodium urate monohydrate (MSU) crystals.

36 , calcium pyrophosphate dihydrate (CPPD), or monosodium urate (MSU) crystals and placed on a microsco

37 ls and damaged tissues release uric acid and monosodium urate (MSU) crystals as important endogenous

38 nvestigated how the endogenous danger signal monosodium urate (MSU) crystals can alter macrophage fun

39 Phagocyte ingestion of monosodium urate (MSU) crystals can induce proinflammato

40 While it is known that monosodium urate (MSU) crystals cause the disease gout,

41 Gout is a form of crystal arthropathy where monosodium urate (MSU) crystals deposit and elicit infla

42 atory disorder associated with deposition of monosodium urate (MSU) crystals in joints and periarticu

43 ith gout predispose them to the formation of monosodium urate (MSU) crystals, soluble urate also prim

44 t do not rely solely on the documentation of monosodium urate (MSU) crystals.

45 he joints of gout patients upon encountering monosodium urate (MSU) crystals.

46 t do not rely solely on the documentation of monosodium urate (MSU) crystals.

47 f calcium pyrophosphate dihydrate (CPPD) and monosodium urate (MSU) deposited in synovium and articul

48 Here, it is reported that monosodium urate (MSU) results in exocytosis of Weibel-P

49 lation of PML by arsenic trioxide suppressed monosodium urate (MSU)-induced IL-1beta production, sugg

50 We found that uric acid (monosodium urate [MSU]) crystals induce a proinflammator

51 xis while exogenous delivery of UA crystals (monosodium urate, MSU) restored the allergic phenotype.

52 pTG and wild-type mice, and in both in vivo (monosodium urate peritonitis) and in vitro models of inf