ライフサイエンスコーパス: monosome

1 ensity centrifugation (to recover intact 70S monosomes).

2 ubunit of the mitochondrial ribosome and the monosome.

3 SU and consequently reduced formation of the monosome.

4 03 x 10(-7) cm(2) s(-1) for the 70 S E. coli monosome.

5 NA from polyribosome-associated polysomes to monosomes.

6 ors, ribosomal large and small subunits, and monosomes.

7 uses an accumulation of 60S subunits and 80S monosomes.

8 nd c-myc transcripts from heavy polysomes to monosomes.

9 cles and complete conversion of polysomes to monosomes.

10 ts with 60 S ribosomal subunits but not with monosomes.

11 accompanied by the transient increase in 70S monosomes.

12 omes exist in two populations: polysomes and monosomes.

13 ned their potency at converting polysomes to monosomes across other commonly used model organisms, in

14 f MPV17L2 results in marked decreases in the monosome and both subunits of the mitochondrial ribosome

15 no substantial increase in the size of their monosome and polysome peaks, suggesting that similar num

16 anslation was examined by RT-PCR analysis of monosome and polysome sucrose gradient fractions from My

17 was fractionated into pools of polysomes and monosomes and a ribosome-free pool.

18 RPG knockdowns decreased miRNAs in monosomes and increased their target mRNAs in polysomes.

19 sively, to what extent translation occurs on monosomes and its importance for overall translational o

20 Finally, the levels 40 S, 60 S, and 80 S monosomes and polyribosomes are unaffected by the loss o

21 miRNA profiling of monosomes and polysomes demonstrated that miRNAs cosedim

22 40S and 60S ribosomal subunits but also 80S monosomes and polysomes in the remaining kidney.

23 from 9.8-fold to 6.0-fold while flux between monosomes and polysomes remained constant.

24 affect total c-jun mRNA or its flux between monosomes and polysomes.

25 dberg ribosomal subunits, intact 80-Svedberg monosomes and polysomes.

26 ted the polysome profile in the direction of monosomes and ribosomal subunits.

27 Hyperphosphorylated 9G8 was present in monosomes and small polyribosomes, whereas soluble fract

28 observations, sucrose gradient purified 80S monosomes and translating polysomes each contained TbRAC

29 PA), and c-jun mRNA was quantified in total, monosome, and polysome fractions by real-time polymerase

30 nits to create the translationally competent monosome, and provide evidence that assembly of the smal

31 We found that the vast majority of 80S monosomes are elongating, not initiating.

32 the small mitoribosomal subunit and impaired monosome assembly.

33 iling by microarray analysis of polysome and monosome associated mRNAs in wild-type and mutant cells

34 bunit and polysome content and decreased 80S monosome content.

35 These PTC-containing mRNAs were monosome-enriched and rarely contributed to expression o

36 Our data highlight the importance of monosomes for the translation of highly regulated mRNAs.

37 ion of several mt-LSU proteins and decreased monosome formation.

38 gulatory proteins tend to be enriched in the monosome fraction.

39 au1-dependent, being mainly localized in the monosome fractions when Stau1 is downregulated and exclu

40 nsional reconstruction of the eukaryotic 80S monosome from a frozen-hydrated electron microscopic pre

41 ity while thoroughly converting polysomes to monosomes in all examined species.

42 e (39S) subunit of the ribosome from the 55S monosomes in an active process.

43 g to examine the translational status of 80S monosomes in Saccharomyces cerevisiae.

44 Loss of polysomes with increased 80S monosomes in the polyamine-depleted cells suggests a dir

45 somal subunits relative to the amount of 70S monosomes increase in Era-depleted and E200K mutant cell

46 d the shift in translation from polysomes to monosomes is attenuated, suggesting puf3Delta cells perc

47 The sedimentation coefficients of the intact monosome, large subunit, and small subunit were 55, 39,

48 Further, most mRNAs exhibit some degree of monosome occupancy, with monosomes predominating on nons

49 free 60S ribosomal subunits but not with 80S monosomes or polysomal ribosomes, indicating that it is

50 free 60S ribosomal subunits but not with 80S monosomes or polysomal ribosomes, indicating that it is

51 rge (50S) ribosomal subunit but not with 70S monosomes or with translating ribosomes.

52 An increased monosome peak with moderate ribosomal disaggregation in

53 ibit some degree of monosome occupancy, with monosomes predominating on nonsense-mediated decay (NMD)

54 and was associated with a decreased polysome/monosome ratio that is indicative of reduced protein tra

55 rom heavy polysomes to lighter polysomes and monosomes, suggesting that Gemin5 functions as an activa

56 ofile analysis, where a shift in the mRNA to monosomes was apparent in response to SCD2 silencing.

57 IF3(mt) does not bind 55S monosomes, while the deletion derivative binds slightly