ライフサイエンスコーパス: monospecific

1 y repertoire of the quasimonoclonal mouse is monospecific.

2 ly occurring IgG antibodies are bivalent and monospecific.

3 g) mice peripheral T cells were functionally monospecific.

4 Monospecific (177)Lu- and (111)In-labeled trastuzumab Fa

5 EG24-EGF or (111)In-DTPA-Fab-PEG24-EGF or to monospecific (177)Lu- or (111)In-labeled trastuzumab Fab

6 butes to the development of lymphocytes with monospecific Ag receptors.

7 eutrophils) has prevented the development of monospecific agents against these therapeutic targets.

8 bsRICs were more effective than monospecific agents.

9 thane consumption either as single cells, in monospecific aggregates, or in multispecies consortia.

10 on with bacteria, they also were observed as monospecific aggregations and as single cells.

11 -1 archaeal group more frequently existed in monospecific aggregations or as single filaments, appare

12 ematosus (SLE) (group 1), 2) sera with known monospecific ANA reactivity (group 2), and 3) sera from

13 We analyzed monospecific and cross-reactive recognition by diverse T

14 ntibody response in SHIV-infected monkeys is monospecific and directed against epitopes composed of t

15 Using Western blots probed with two Msp2-monospecific and one Msp2-monoclonal antibodies, we dete

16 Monospecific AnkA antibodies reacted with proteins in HG

17 CD38, it immunoreacted with three different monospecific anti-CD38 antibodies on immunoblots, and it

18 osomes from phenobarbital-treated males with monospecific anti-CYP2B monoclonal antibodies (Mab) inhi

19 Shear-loading of monospecific anti-fascin immunoglobulins, which block th

20 Immunohistochemistry employing a monospecific anti-FLIP antibody was performed on RA and

21 antibody against human NGAL as well as by a monospecific anti-human MMP-9 antibody.

22 Immunoprecipitation experiments using monospecific anti-IAP100 antibodies and a nonionic deter

23 he same 185-kD glomerular protein as did the monospecific anti-PLA(2)R antibody.

24 One monospecific anti-single-stranded (ss) DNA (11F8) induce

25 Using monospecific anti-SpKAP115 antibodies we have accomplish

26 Immunoblot analysis using monospecific anti-VlsE revealed the presence of prominen

27 cacy against Streptococcus pneumoniae, human monospecific antibodies (MAbs) to serotype 3 pneumococca

28 We used fluorescent microscopy, monospecific antibodies against complement components, f

29 roblotting and immunochemical staining using monospecific antibodies against SAP-2, two or three majo

30 Double indirect immunofluorescence using monospecific antibodies demonstrated that a subset of CE

31 Monospecific antibodies directed against the four distin

32 Anti-recombinant ePAD monospecific antibodies localized the molecule to the cy

33 Monospecific antibodies raised against four synthetic pe

34 on and immunoelectron microscopy using these monospecific antibodies revealed that PfNT1 localizes pr

35 During the past decade, monospecific antibodies targeting cell-surface receptors

36 e immunologic evaluation with monoclonal and monospecific antibodies to be identical to or an isoform

37 o acid sequencing and Western analysis using monospecific antibodies to each toxin demonstrated that

38 microinjection studies were performed using monospecific antibodies to myosin IIA and IIB isotypes.

39 ycan plays in the developing nervous system, monospecific antibodies were prepared and used to locali

40 Monospecific antibodies were used to identify ACE, macro

41 By using these monospecific antibodies, a 1.096-kb human cDNA that enco

42 hepatoma cells by immunohistochemistry with monospecific antibodies, confocal microscopy, and matrix

43 laminin alpha, beta, and gamma chains using monospecific antibodies.

44 unoprecipitation of the PB1-PB2 complex with monospecific antibodies.

45 by coimmunoprecipitation (co-IP) assay using monospecific antibodies.

46 n) were identified on adjacent sections with monospecific antibodies.

47 ined by immunohistochemistry with the use of monospecific antibodies.

48 ion of NOS2 in patients with AD, using three monospecific antibodies: a previously described polyclon

49 Monospecific antibody fragments produced in bacteria lac

50 Using a monospecific antibody raised against native Xp54, its pr

51 mmunoscreening of an expression library with monospecific antibody resulted in the isolation of a cDN

52 tates did not contain RNA polymerase I, as a monospecific antibody to the 194-kDa subunit of RNA poly

53 An Fab fragment of a monospecific antibody, which binds to residues 39 to 55

54 ty and location of the target antigen with a monospecific antibody.

55 lic fragments of aggrecan were detected with monospecific antipeptide antibodies.

56 The topology of Fpn was determined using monospecific antisera against its different epitopes, in

57 Monoclonal and monospecific antisera against MSPs 1 through 5, initiall

58 Antibody supershift assays using monospecific antisera against NF-kappaB subunits (p50 an

59 eu121 --> Lys126 and Phe198 --> Lys220), and monospecific antisera against p45 and RHL-1 cross-reacte

60 Immunofluorescence methods using monospecific antisera and distinct fluorophores identifi

61 114 phase partitioning, and used to generate monospecific antisera in rats.

62 By using monospecific antisera in Western blot and flow cytometry

63 surfaces by immunofluorescence assays using monospecific antisera raised to the recombinant protein

64 Surface localization of OmcB was shown using monospecific antisera specific to the 20-mer OmcB peptid

65 Here we have raised for the first time monospecific antisera to CENP-A [3], a 17 kD centromere-

66 Immunofluorescence staining with monospecific antisera to purified PorB revealed antigen

67 igenic determinants were surface accessible, monospecific antisera were raised to the PorB peptides a

68 encing were confirmed by neutralization with monospecific antisera.

69 taining both proteins were precipitated with monospecific antisera.

70 purified and used to raise rabbit polyclonal monospecific antisera.

71 ction were identified by immunoblotting with monospecific antiserum and convalescent rat serum in add

72 ved only in yolk sac, kidney, and ileum with monospecific antiserum for p400.

73 e pretreated intranasally with RSVIg or with monospecific antiserum obtained from animals previously

74 ts, sera from chronically infected mice, and monospecific antiserum to the antigenic variation protei

75 purified was used to raise rabbit polyclonal monospecific antiserum.

76 Isotopic analyses suggest that monospecific archaeal cells and cell aggregates were act

77 of the expected size on immunoblots and were monospecific based on peptide competition studies.

78 can limit the efficacy of receptor-targeted monospecific-based therapies.

79 and Pro/Pre B cells that do not express KIT, monospecific BCR-ABL inhibition was quantitatively as ef

80 nov., based primarily on monospecific bedding plane assemblages from the Lower-Mi

81 tantial and perennial colonization featuring monospecific biofilms at the surface of the aggregates.

82 repertoire of this quasi-monoclonal mouse is monospecific, but somatic hypermutation and secondary re

83 ed to recombinant BmpA (rBmpA) were rendered monospecific by absorption with rBmpB.

84 loma cell lines, and was more effective than monospecific CD20-targeted MAb-IFNalpha or a mixture com

85 or PD-L1-deficient mice induced K(b)/A12-21-monospecific CD8(+) T cells and autoimmune diabetes.

86 We found that monospecific CD8+ T cells introduced into tolerant anima

87 produced IFN-gamma, but differed from EBNA1-monospecific cells in their capability to produce interl

88 tissues by immunohistochemistry with both a monospecific chicken anti-Neu5Gc antibody and with affin

89 ific antibody per ml from affinity-isolated, monospecific chicken antibody preparations and to measur

90 antibody specifically from IgY fractions of monospecific chicken antibody preparations.

91 80% more species of twig-nesting ants than a monospecific collection of twigs.

92 sandy sea bed and lived in dense, typically monospecific concentrations.

93 Immunohistochemical staining with a monospecific COX-2 antibody confirmed that increases in

94 Renin is a monospecific enzyme that catalyzes the rate-limiting ste

95 levels of expansion than T cells recognizing monospecific epitopes because of more frequent stimulati

96 rent Fabs together, we produced a variety of monospecific F(ab')(2)-like molecules with activities sp

97 6 h postinjection; n = 4) compared with each monospecific Fab tracer.

98 ro with an anti-CD4 mAb allowed T cells from monospecific female TCR-transgenic mice against the male

99 The monospecific fern genus Cystodium (Cystodiaceae; Polypod

100 ted with an antibody documented herein to be monospecific for human NOS2.

101 y positive spots from probes predicted to be monospecific for influenza virus species, subtype, host

102 t was then affinity purified and shown to be monospecific for MAP4.

103 Two different antibodies monospecific for myeloperoxidase identified a 60-kd prot

104 e strains, A1(M).RAG1(-/-) and Marilyn, each monospecific for the male antigen Dby.

105 -glucose dehydrogenase, corresponding to the monospecific form, ubiquitous amongst plants and animals

106 We show here, however, that anti-H-Y monospecific, H-2(b-restricted MataHari CD8(+) T cells r

107 Three such constructs, 20-20, a monospecific HexAb comprising 6 Fabs of veltuzumab (huma

108 Using immunoperoxidase microscopy with a new monospecific human iNOS antibody (NO-53), the cellular d

109 This represented an essentially monospecific IgG population.

110 The Cf-2 protein, originally identified as a monospecific immune receptor for the leaf mold fungus Cl

111 loride creating an aqueous aluminum solution monospecific in MAl12(7/8+).

112 Site(-1) was found to be monospecific in the Erbin PDZ domain (accepts tryptophan

113 Using unique, monospecific inhibitors against MASP-1 and MASP-2, we co

114 Lineatriton, long thought to be a unique monospecific lineage, is polyphyletic.

115 isms that orchestrate the differentiation of monospecific lymphocytes while suppressing oncogenic Ag

116 t required for measurable insulin binding by monospecific mAb from adult mice.

117 BM (CD20(+)/HLA-DR(+) myeloma) compared with monospecific MAb-IFNalpha, which targets only HLA-DR or

118 We evolved a pair of monospecific MASP inhibitors.

119 In assays involving alternating stripes of monospecific matrices, human control GCs exhibited no pr

120 Importantly, monospecific MSA-1 and RAP-1 antisera each inhibited spo

121 Monospecific neuraminidase (NA) subtype probes were insu

122 Notably, children with preexisting monospecific neutralizing antibody responses were more l

123 Multivalent antibodies, either monospecific or bispecific, may improve the efficacy of

124 Using coimmunoprecipitation with monospecific or monoclonal antibodies, we observed that

125 itute a group of T cells that express mainly monospecific or oligoclonal T cell receptors (TCRs).

126 In contrast, human Tie-2-monospecific pAd-1S05 intrabody did not affect the growt

127 The antigen-binding fragment (Fab) of a monospecific peptide 1 (P1) antibody, which was raised a

128 otype neutralization could be generated from monospecific plasma.

129 Monospecific polyclonal anti-p45 IgG detected p45 in cru

130 We have produced monospecific polyclonal antibodies against TPH1 and TPH2

131 ic compounds with high affinity for LRAT and monospecific polyclonal antibodies raised in rabbits aga

132 Monospecific polyclonal antibodies to the 100-kDa protei

133 We have made monospecific polyclonal antibodies to the protein and co

134 s by analyzing the consequences of injecting monospecific polyclonal antibodies to xNup98 into X. lae

135 In addition, monospecific polyclonal antibodies were used to demonstr

136 cted in wild-type-infected cells with rabbit monospecific polyclonal antibody directed against a fusi

137 Using a monospecific polyclonal antibody raised against SirR to

138 A monospecific polyclonal antiserum to an Escherichia coli

139 Using monospecific polyclonal peptide antisera that recognize

140 he other, they are present as an essentially monospecific population (VH3H9/Vkappa8).

141 ls, as the induction of CD25 expression on a monospecific population of T cells derived from TCR tran

142 n the current study, mAb BM8 was used as the monospecific probe to characterize its antigen (AgBM8) i

143 Monospecific rabbit antibodies to FP-1 recognize in cult

144 sion in rat brain and spinal cord by using a monospecific rabbit antiserum produced against bacterial

145 They all reacted with monospecific rabbit antiserum to the purified S-layer of

146 blocked by soluble LIMPII fusion protein, by monospecific rabbit IgG directed against the LIMPII pept

147 Monospecific rabbit polyclonal antibody produced to a gl

148 re, the thawed gel is sandwiched between two monospecific reagent DET gels, leading to magenta and bl

149 d from the brain of an SSPE patient, or on a monospecific recombinant Fab identified from SSPE brain.

150 However, these assays are mostly monospecific, requiring separate amplifications for each

151 giogenic activity, whereas the effect of the monospecific scFv intrabodies was weaker.

152 formation in Matrigel plugs in vivo, whereas monospecific scVEGF mutants that bind VEGFR2 or alpha(v)

153 Compared to monospecific scVEGF mutants that bind VEGFR2 or alpha(v)

154 Cross-reactivity with monospecific sera and monoclonal antibodies to p40 was f

155 eened a panel of murine monoclonal and human monospecific sera reactive with known autoantigens for t

156 iofilm composition (natural multispecies vs. monospecific species) may influence the outcomes.

157 ly equivalent positions along creek banks in monospecific stands of Spartina alterniflora (smooth cor

158 The marine bacterium Vibrio fischeri is the monospecific symbiont of the Hawaiian bobtail squid, Eup

159 Transfer of polyclonal monospecific syngeneic mouse anti-Neu5Gc serum also enha

160 epresented the same Th1 phenotype as that of monospecific T cells recognizing MBP(93-105).

161 ired tolerance was dominant, such that naive monospecific T cells were not able to override tolerance

162 This subset can be derived from mature monospecific T cells without "tutoring" by other T cells

163 he same antigen in the same cancer cells via monospecific T cells, which have similar pMHC and pMHC-T

164 n on adoptive transfer compared with that of monospecific T-cell clones.

165 Using mutant and transgenic animals with a monospecific TCR, we discovered increased numbers of MP

166 lso able to induce tolerance in vivo in such monospecific TCR-transgenic mice, and this too was depen

167 Analysis of the effect of the monospecific TCR-transgenic T cells on the host response

168 o circumvent the limitations of conventional monospecific therapies and achieve enhanced therapeutic

169 s showed that the monobodies are essentially monospecific to SHP2.