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3 ronal progenitor domains is dependent on the morphogenic action of the secreted protein Sonic hedgeho
5 renal injury and are known to induce marked morphogenic actions in cultured tubular epithelial cells
6 tropic factor with mitogenic, motogenic, and morphogenic activities on a number of different cell typ
7 hyte have been identified and, recently, the morphogenic activity of the plant hormone auxin has been
11 wth factor, Met signaling confers mitogenic, morphogenic, and motogenic activity to various cells.
13 have yielded insights into the regulation of morphogenic cell migration, such as the zebrafish latera
14 nd growth factor gene expression highlighted morphogenic cell processes within the embryoid bodies, s
16 survival, motility, and invasion as well as morphogenic changes that stimulate tissue repair and reg
19 ew model for how an evolutionarily conserved morphogenic cue and its cognate receptors can pattern a
21 etastatic disease, little is known about the morphogenic cues and signaling pathways that govern glan
23 nts) using morpholinos caused severe cardiac morphogenic defects including a cardiac looping failure
24 ApoER2 knock-out (KO) mice had rod bipolar morphogenic defects, altered A-II amacrine dendritic dev
25 type, single rpn5a mutants display a host of morphogenic defects, including abnormal embryogenesis, p
26 that these ECM filaments have a reproducible morphogenic destiny that is characterized by directed tr
30 targeting this axis in dealing with vascular morphogenic disorders and vascular normalization of tumo
31 ses, and it appeared to represent a specific morphogenic effect because neither axonal growth nor cel
32 ed regions (UTRs) along with suppressor with morphogenic effect on genitalia 5 (SMG5) and SMG7 but no
35 enal tubular epithelial cells and that these morphogenic effects require activation of the phosphatid
36 known to influence neoplasia and also exert morphogenic effects via the urogenital sinus mesenchyme.
41 Because wound healing largely mimics the morphogenic events that occur during development, we pro
42 expressed in the epithelium throughout these morphogenic events, and mice lacking either factor exhib
45 Tenascin-C (TNC) is a mechano-regulated, morphogenic, extracellular matrix protein that is associ
47 nt osteoinductivity of EBM demonstrates that morphogenic factors expressed by ESCs undergoing osteoge
48 ch is in turn dependent on the Wnt family of morphogenic factors for autophosphorylation or transacti
51 g forces physically distort the shape of the morphogenic field, causing local maxima of epithelial si
53 differences in the abilities of these three morphogenic forms of C. albicans to adhere to endotheliu
54 hus, although TTF1 appears to fulfill only a morphogenic function in the ventral telencephalon, once
55 pathway is well known for its mitogenic and morphogenic functions during development, and HH signali
56 dependent protein kinase II (CaMKII)beta has morphogenic functions in neurons not shared by the alpha
57 tment and regulation of proteins involved in morphogenic functions, especially elongation and divisio
58 vents aberrant Hh signaling posterior to the morphogenic furrow, which is essential for normal eye de
61 rong evidence against the role of long-range morphogenic gradients or biased cell exchange in the dis
63 to direct guidance of cell migration by Wnt morphogenic gradients, cell migration can also be contro
64 g deleted on chromosome ten (PTEN) regulates morphogenic growth of benign MDCK (Madin Darby Canine Ki
65 receptor (VDR) are required for normal post-morphogenic hair cycles; however, the molecular mechanis
67 network junctions are formed by two separate morphogenic mechanisms of anastomosis and cluster thinni
68 le is known about the role of these vascular morphogenic molecules in the pathogenesis of atheroscler
69 ates how spatiotemporal coordination between morphogenic movements and fate determination critically
72 r, little is known about Rac function in the morphogenic movements that drive epithelial tube formati
73 r study revealed fewer (and different) inter-morphogenic pathway crosstalk connections than expected;
74 tin, sheds light for the first time into the morphogenic pathway of cytoskeletal structures that are
76 results suggest that MreC and MreD act in a morphogenic pathway that couples the helical cytosolic M
77 Crosstalk was measured by the ability of one morphogenic pathway to cross-activate core transcription
78 uxiliary mechanism of metabolic control by a morphogenic pathway with relevant implications in develo
85 seedling development, leading to a distinct morphogenic plan (skotomorphogenesis) [1], characterized
88 ch overexpression and alteration of a normal morphogenic process promote the development of cancer in
92 integrin alpha6 signaling during a cellular morphogenic process; 2) the decreased surface expression
93 suitable for genetic optimization using the morphogenics process and have shown potential for large-
94 of gonad formation, indicating that separate morphogenic processes are at work during gonadogenesis.
96 potential Ca(2)(+) mediator of many of these morphogenic processes is CaMK-II, a conserved calmodulin
98 ol of cell proliferation and apoptosis, plus morphogenic processes that sculpt vasculature, parenchym
99 othesize that PTEN controls Cdc42 -dependent morphogenic processes through a beta-Arrestin1-ARHGAP21
100 that plays important roles in developmental morphogenic processes, is abnormally elevated in the bon
101 endogenous Eph signaling in endothelial cell morphogenic processes, uncovers a novel link between Eph
104 atrix and integrin signaling, suggest that a morphogenic program integrates cell-cell and cell-extrac
105 grown in Matrigel, are restored to a normal morphogenic program when transfected with CEACAM1-4S, th
108 ates endothelial cells (ECs) to produce bone morphogenic protein (BMP) 4, which in turn activates inf
109 K14-Noggin transgenic mouse to modulate bone morphogenic protein (BMP) activity and test the extent o
110 ignaling induces down-regulation of the bone morphogenic protein (BMP) and activin membrane-bound inh
112 hese proteins play an important role in bone morphogenic protein (BMP) and transforming growth factor
114 ion are likely to involve a gradient of bone morphogenic protein (BMP) in conjunction with FGF and Wn
116 ansforming growth factor (TGF)-beta and bone morphogenic protein (BMP) signaling after specification
117 apid bouton budding requires retrograde bone morphogenic protein (BMP) signaling and local alteration
118 and murine hematopoietic cells induced bone morphogenic protein (BMP) signaling and resulted in a ma
120 reduction of synaptic growth-promoting bone morphogenic protein (BMP) signaling at the neuromuscular
121 st whether adult neuronal expression of bone morphogenic protein (BMP) signaling components also play
122 rrespondingly, the distribution of both bone morphogenic protein (BMP) signaling domains and BMP2 imm
123 in injection in neonatal mice increased bone morphogenic protein (BMP) signaling in the ventral hypot
124 In the present study, we show that bone morphogenic protein (Bmp) signaling is a critical regula
126 gulatory hormone, hepcidin, through the bone morphogenic protein (BMP) signaling pathway by acting as
133 rosophila homologue spichthyin inhibits bone morphogenic protein (BMP) signalling, although the relev
134 expression of embryonic globin and key bone morphogenic protein (BMP) target genes, including the he
136 n is controlled jointly by at least the bone morphogenic protein (BMP), WNT, fibroblast growth factor
138 Although GlaMGP binds and inactivates bone morphogenic protein (BMP)-2, a proposed mediator of vasc
144 /C1s, Uegf sea urchin fibropellins, and bone morphogenic protein 1 (CUB) domains, but was severely de
146 r markers atrial natriuretic factor and bone morphogenic protein 10 indicated that proliferating card
147 the suppressive effects of TGF-beta and bone morphogenic protein 2 (BMP-2) on epithelial gene express
148 repression is established by utilizing bone morphogenic protein 2 (BMP-2)-induced chondrogenic diffe
149 -osteogenic factors [Fgf-2, Fgf-18, and bone morphogenic protein 2 (Bmp-2)] still were present in Fgf
154 erived factor-1 (SDF-1), is involved in bone morphogenic protein 2 (BMP2)-induced osteogenic differen
156 or optimal expression in ECs, including bone morphogenic protein 2, cbp/p300-interacting transactivat
157 fferentiated in vitro by treatment with bone morphogenic protein 2, the OBs from TIEG(+/+) calvaria d
158 superfamily, activin A, TGF-beta1, and bone morphogenic protein 4 (BMP-4) have various effects on he
159 tor receptor beta polypeptide (PDGFRb), bone morphogenic protein 4 (BMP-4), and stem cell factor (SCF
161 on, and functional studies, we identify bone morphogenic protein 4 (BMP4) as a mechanosensitive and p
162 f pluripotent C3H10T1/2 stem cells with bone morphogenic protein 4 (BMP4) during proliferation follow
164 osure induces endothelial expression of bone morphogenic protein 4 (BMP4), which in turn may activate
165 em cells to the growth factors FGF2 and bone morphogenic protein 4 (BMP4), which normally promote and
166 ocyte, corresponding to upregulation of bone morphogenic protein 4 mRNA and CTGF mRNA (inhibitors of
167 lants of Hepcidin transcription include bone morphogenic protein 6 (BMP6) and interleukin-6 (IL-6) by
168 haplotypes composed of several SNPs in bone morphogenic protein 6, annexin A2, and klotho were assoc
169 thelial cells to undergo EndMT, whereas bone morphogenic protein 7 (BMP-7) preserved the endothelial
170 In the absence of the growth factor bone morphogenic protein 7 (BMP7), kidney development arrests
171 the genes common to both data sets was bone morphogenic protein 7 (BMP7), whose expression is also s
173 cleotide polymorphisms (SNPs) were near bone morphogenic protein 7 [BMP7: rs75161997, P = 5.34 x 10(-
175 sms, such as fetuin-A, osteopontin, and bone morphogenic protein 7, among others, will be necessary t
176 HOXC6 directly regulates expression of bone morphogenic protein 7, fibroblast growth factor receptor
178 rming growth factor-beta [TGF-beta] and bone morphogenic protein [BMP]) in the dentine that are belie
180 ructure of the homeodomain of the Drosophila morphogenic protein Bicoid (Bcd) complexed with a TAATCC
182 of inhibiting activin signaling but not bone morphogenic protein or platelet-derived growth factor si
183 leads to an up-regulation of endogenous bone morphogenic protein pathway activation, as indicated by
184 transforming growth factor-beta/activin/bone morphogenic protein pathways, we demonstrate a specializ
187 t is driven by direct inhibition of the bone morphogenic protein receptor kinase activin A receptor,
188 including mutations in the gene coding bone morphogenic protein receptor type 2 (BMPR2) and related
189 ed to changes in cell cycle control and bone morphogenic protein receptor type 2 (BMPR2) signaling, a
190 synaptic growth signaling by activated bone morphogenic protein receptors, and live imaging in neuro
191 sistent with a role for activin but not bone morphogenic protein signaling in cardiac dysfunction.
192 encoding inhibitors of WNT and activin/bone morphogenic protein signaling were overrepresented in th
198 cted with noggin, an antagonist of BMP (Bone Morphogenic Protein), we found that BMP expression is re
199 oaches to fusion, as well as the use of bone morphogenic protein, disk arthroplasty, and interspinous
200 nt findings regarding the roles of Wnt, bone morphogenic protein, PtdIns(3,4,5) kinase, and Notch pat
201 arding signaling pathways, such as Wnt, bone morphogenic protein, PtdIns(3,4,5) kinase, and Notch, in
203 where DCVs contain neuropeptides and a bone morphogenic protein, show that activity-dependent replen
204 ortance of pathways such as Wnt, Notch, bone morphogenic protein, Sonic hedgehog and fibroblast growt
205 revealed that procollagen C-proteinases bone morphogenic protein-1 and mammalians Tolloid and procoll
206 of leukemia inhibitory factor (LIF) and bone-morphogenic protein-2 (BMP-2)-induced mouse ES cell (mES
210 studies demonstrate a pivotal role for bone morphogenic protein-6 (BMP6) and matriptase-2, a protein
212 , we tested the therapeutic efficacy of bone morphogenic protein-7 (BMP-7) and inhibitors of advanced
215 1 because a combination of IGFBP-3 with bone morphogenic protein-7 (BMP-7), another member of the TGF
217 e phosphorylation of Smad1 and Smad2 by bone morphogenic protein-7 and transforming growth factor-bet
218 ion of TGF-beta1 with recombinant human bone morphogenic protein-7 prevents this process and prevents
219 testinal epithelial cells in vitro, and bone morphogenic protein-7, an antagonist of TGF-beta1, inhib
220 o showed hyperactivation of alternative bone morphogenic protein-activated Smad1/5/8 signaling and in
221 formation of the caudal vein plexus, a bone morphogenic protein-responsive process, an effect rescue
223 esis by targeting endothelial cell (EC) bone morphogenic protein/SMAD1 signaling in vitro and in vivo
224 s demonstrate that miR-26a inhibits the bone morphogenic protein/SMAD1 signaling pathway in ECs by bi
225 ngs establish miR-26a as a regulator of bone morphogenic protein/SMAD1-mediated EC angiogenic respons
226 Multiple signaling molecules, including bone morphogenic proteins (BMP) and fibroblast growth factors
227 se include the Notch, Wnt/beta-catenin, bone morphogenic proteins (Bmp) and Sonic Hedgehog (Shh) path
228 We report that DeltaNp63alpha activates bone morphogenic proteins (BMP) signaling by inducing the exp
229 e cerebellar region of the neural tube, bone morphogenic proteins (BMP6/7 and GDF7) that induce early
230 ive conditions induce the expression of bone morphogenic proteins (BMPs 2 and 4) in cultured endothel
234 or beta (TGF-beta) superfamily, such as bone morphogenic proteins (BMPs) and TGF-beta, are key regula
235 of local peptide signals, primarily the bone morphogenic proteins (BMPs) and the Wingless-related gen
236 (AV) cusps have increased expression of bone morphogenic proteins (BMPs) and transforming growth fact
242 of the transforming growth factor-beta, bone morphogenic proteins (BMPs), and activin signaling.
243 sses endogenous growth factors, such as bone morphogenic proteins (BMPs), which facilitate maintenanc
246 g that they represent a widespread family of morphogenic proteins controlling cell wall biogenesis by
247 s in the PLAB gene, encoding one of the bone morphogenic proteins in the transforming growth factor-b
249 gnals from adjacent endoderm, including bone morphogenic proteins, and is antagonized by a second sec
250 lated by neuregulin, notch ligands, and bone morphogenic proteins, as these factors are expressed in
251 two homologous secreted antagonists of bone morphogenic proteins, have been shown to regulate early
258 temporal dynamics of stem cell signaling and morphogenic remodeling to direct the differentiation of
260 ocks VEGF-165 binding to Nrp-1) prevents the morphogenic response and the phosphorylation of VEGFR-2
262 ated to be critical in coordinating vascular morphogenic responses by controlling hematopoietic cytok
263 K-ras is sufficient to elicit mitogenic and morphogenic responses in pancreatic ductal cells and hen
264 M (OSM) induces potent growth-inhibitory and morphogenic responses in several different tumor cell ty
269 ll fusion, whereas Ste20 fulfills a distinct morphogenic role and is required to maintain polarity in
270 ous experimental and theoretical analyses of morphogenic scaling that have focused on compensatory ch
273 ce is given here that light acts mainly as a morphogenic signal in the triggering of bud outgrowth an
275 discuss the emerging role of Wnt proteins in morphogenic signaling and ciliary biology during health
276 t the mechanisms that coordinate and control morphogenic signaling during effective liver regeneratio
279 ic stellate cells (HSCs) and reactivation of morphogenic signaling pathways that modulate epithelial-
281 hen localized to the cytoplasmic surface and morphogenic signaling when localized to the extracellula
283 skeleton converges or coordinates with other morphogenic signalling systems to control feather bud de
284 ral nervous system and generates dorsalising morphogenic signals along the length of the neuraxis.
286 of meninges, we have identified a cascade of morphogenic signals initiated by the meninges that regul
287 al epithelial cells to the dedifferentiating morphogenic signals of hepatocyte growth factor (HGF) wa
288 ing during gastrulation, and is regulated by morphogenic signals such as the FGF/MAPK and activin pat
289 cient mesenchymal progenitors cause aberrant morphogenic signals, and identify an expression signatur
292 ant formed near-normal levels of the various morphogenic stages of infectious virus particles and sup
298 platform process that combines hybridoma and morphogenics technologies for the generation of fully hu
299 infection appears to be associated with the morphogenic transformation of C. albicans yeasts into in
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