ライフサイエンスコーパス: morphologic change

1 he development of aneuploidy, and stimulated morphologic changes.

2 ent of RPE cells in vitro results in similar morphologic changes.

3 n 0 and 24 hours, and photographed to detect morphologic changes.

4 ment of lenses with H(2)O(2) caused distinct morphologic changes.

5 ithin tumor cells as opposed to identifiable morphologic changes.

6 r sheath in the CM tips in addition to other morphologic changes.

7 s distance moved in 2 hours and examined for morphologic changes.

8 ir cells consists of a progressive series of morphologic changes.

9 isely monitoring the sequence of RPE-related morphologic changes.

10 HFD-induced delay in intestinal transit and morphologic changes.

11 ting in widespread, although trait-specific, morphologic changes.

12 They do not show obvious morphologic changes.

13 nt thermal load should be cognizant of these morphologic changes.

14 ects progressed with time and paralleled the morphologic changes.

15 dy the growth pattern of CNVM and associated morphologic changes.

16 ion, but central corneal DCs assumed extreme morphologic changes.

17 tes of surviving large ON-type cells undergo morphologic changes.

18 ort and long half-life proteins and dramatic morphologic changes.

19 in their identification of right ventricular morphologic changes.

20 s requires that tumor cells undergo dramatic morphologic changes, a process regulated by Rho GTPases.

21 Platelet activation results in profound morphologic changes accompanied by release of granule co

22 o reduced FGF-2 levels and partially blocked morphologic changes after freezing.

23 Among the first morphologic changes after initiation of the apoptotic pr

24 UVR, TNF-alpha, and cis-UCA cause similar morphologic changes among Langerhans cells, which spawns

25 f the transformed phenotype, including fewer morphologic changes, an increase in stress fiber cytoske

26 MT1-MMP-induced morphologic change and cell scattering were abrogated by

27 The morphologic change and p21 up-regulation still were obse

28 Forty-eight cancers were assessed for morphologic change and volume doubling time (VDT), which

29 ement was present in the ankle joints, where morphologic changes and abnormal calcification of these

30 These recipient cells display morphologic changes and acquire tumor-associated phenoty

31 st cancer cells was associated with dramatic morphologic changes and actin cytoskeleton remodeling, w

32 hibition of RhoC activity results in drastic morphologic changes and alterations in the expression an

33 nd integrin engagement signals, resulting in morphologic changes and amplified chemotaxis to an other

34 attenuated TGF-beta-induced cytoskeletal and morphologic changes and apoptosis as did treatment with

35 Between groups, morphologic changes and CD3(+) intraepithelial lymphocyt

36 t-passage stromal fibroblast cell death with morphologic changes and DNA fragmentation consistent wit

37 f the K1 gene in rodent fibroblasts produced morphologic changes and focus formation indicative of tr

38 of the R1 gene in Rat-1 fibroblasts induced morphologic changes and focus formation, and injection o

39 Both S91 cells and NHEM exhibit morphologic changes and growth arrest indicative of diff

40 of the CML blast cells occurred as shown by morphologic changes and induction of secondary granule-s

41 oth human and rabbit) demonstrated extensive morphologic changes and inhibition of proliferation when

42 on and antimycin treatment), as evidenced by morphologic changes and internucleosomal DNA cleavage.

43 EMT in MCF10A cells was shown by morphologic changes and loss of E-cadherin/beta-catenin-

44 Morphologic changes and loss of lipid droplets were more

45 No evidence of morphologic changes and no significant difference in the

46 imal hyperplasia associated with endothelial morphologic changes and prominent vascular and perivascu

47 d cell-matrix interaction that is evident by morphologic changes and reduced focal adhesion complex f

48 on prevented H2O2 from inducing mitochondria morphologic changes and reduction of cytochrome b/c.

49 ell invasion that is accompanied by profound morphologic changes and robust reduction in expression l

50 iferation is only partly responsible for the morphologic changes and that other mechanisms such as de

51 Morphologic changes and their relationship to EFL and fa

52 (CT)-determined size, morphology, location, morphologic change, and growth rate of incidence and pre

53 to 14 days resulted in proliferative arrest, morphologic changes, and apoptosis characteristic of cel

54 ectron microscopy was applied to demonstrate morphologic changes, and Safranin O staining was perform

55 HMEC-E6 cells as evidenced by characteristic morphologic changes, annexin V binding, and DNA fragment

56 -treated PR transfectants showed significant morphologic change, appearing more flattened and spread

57 atients and to determine whether distinctive morphologic changes are associated with mutations in thi

58 ich clarify their pathogenesis and attendant morphologic changes are highlighted.

59 EOM morphologic changes are highly correlated with degrees o

60 to Purkinje cells, neuronal dysfunction and morphologic changes are observed without the formation o

61 roughness, surface contraction, and stromal morphologic changes are supportive of this interaction.

62 se hydrodynamic changes are likely driven by morphologic changes associated with AP collapse and hern

63 s and/or substrates that are relevant to the morphologic changes associated with cell division.

64 expression of the monocytic marker CD14 and morphologic changes associated with differentiation.

65 ng technique for visualizing and quantifying morphologic changes associated with experimental laser-i

66 ociated renal injury and late functional and morphologic changes associated with the interval of dono

67 ntitative assessment of signal intensity and morphologic changes before and after UAE.

68 by pro-HB-EGF not only resulted in cellular morphologic change but also decreased cell motility and

69 t kidneys, overexpression of CCN3 induced no morphologic changes but regulated glomerular gene transc

70 levels of H(2)O(2) (0.5 mM) induced similar morphologic changes, but sooner (within 1 hour) and more

71 phosphate (PARP), and examination of nuclear morphologic changes by Hoechst DNA nuclear staining and

72 , and to promote EMT-like changes, including morphologic changes, cell migration, and invasion.

73 markers and the formation of round cells, a morphologic change characteristic of EHT.

74 Morphologic changes characteristic of apoptosis were ind

75 viability of dendritic cells accompanied by morphologic changes characteristic of autophagy and imma

76 detectable leukotoxin failed to exhibit the morphologic changes characteristic of cells undergoing a

77 the VEGFR-1 ligands VEGF-A and VEGF-B led to morphologic changes characteristic of EMT, including los

78 m ionophore (CI), but not CI alone exhibited morphologic changes characteristic of mature DCs and exp

79 ischemia and reperfusion caused significant morphologic changes characterized by loss of villus epit

80 amic process characterized by phenotypic and morphologic changes concomitant with increased migratory

81 Ultrastructural morphologic changes consistent with apoptosis were obser

82 linically viable methodologies either detect morphologic changes (CT/ MR), recruitment of immune cell

83 elsolin may be one physiological effector of morphologic change during apoptosis.

84 Physical forces generated by cells drive morphologic changes during development and can feedback

85 lular functions, including cell motility and morphologic changes during differentiation.

86 dult zebrafish retina and reveal the dynamic morphologic changes during either light-induced damage a

87 Hsp27 may participate in morphologic changes during granule-mediated lysis.

88 angiography can depict intracranial vascular morphologic changes during treatment of brain metastases

89 ransformation of NIH 3T3 cells, resulting in morphologic changes, focus formation, and growth in redu

90 asive phenotypes, including the induction of morphologic changes from the epithelial-to-mesenchymal t

91 produces adverse effects including cellular morphologic changes, growth rate attenuation and alterat

92 Metabolic and morphologic changes have been described in patients with

93 ility by inducing apoptosis, as indicated by morphologic changes, histologic evidence of nuclear cond

94 Nonspecific morphologic changes, however, were the most common histo

95 c expression of Tiam1 in these clones led to morphologic changes identical to biologically selected c

96 on was observed well before the detection of morphologic change in both the lens and the retina.

97 However, a dose-dependent morphologic change in disorganization of the subplate wa

98 yoblast transfectants exhibited a pronounced morphologic change in response to exogenous FGF-1.

99 eriodontitis induction, there was no obvious morphologic change in the periodontium, although slight

100 th collagen- and vitreous-treatment caused a morphologic change in the RPE cells to a more fibroblast

101 activation of the K-ras oncogene and display morphologic changes in alveolar epithelial cells that re

102 The observed morphologic changes in bovine leukocytes were leukotoxin

103 electron microscope demonstrated significant morphologic changes in cells perfused with all concentra

104 The potential of ACEA 1021 to produce morphologic changes in cerebrocortical neurons of the ra

105 mechanisms by which calcium signals lead to morphologic changes in dendrites are not well understood

106 One signal, BMP4, has been shown to induce morphologic changes in dental mesenchyme and mesenchymal

107 emonstrated to regulate cortical actin-based morphologic changes in Dictyostelium and the oxidative b

108 levels of ethanol that did not cause obvious morphologic changes in either the body or retina did aff

109 n also detect and define the hemodynamic and morphologic changes in HF over time and might be equival

110 sforming growth factor beta1 induce profound morphologic changes in immature articular cartilage.

111 mor regression in the absence of significant morphologic changes in kidney, liver, or heart.

112 5(OH)(2)D levels are associated with adverse morphologic changes in large arteries, and this may be m

113 Exudate evoked morphologic changes in macrophages in vitro like that of

114 e find that the onset of paralysis parallels morphologic changes in motor neuron cell bodies in the l

115 k of replication, high doses of mCMV induced morphologic changes in neurons and glia from hamster and

116 Exercise training (ET) causes functional and morphologic changes in normal and injured brain.

117 sis of bone metastasis; however, CT revealed morphologic changes in only half of the lesions assigned

118 ducts may be associated with transient gross morphologic changes in oral soft tissues.

119 No morphologic changes in osteoblasts were observed, and bo

120 Morphologic changes in specific cell populations were ev

121 ting mAb, designated 3E2, elicited prominent morphologic changes in sporozoites and merozoites charac

122 Purified BFT causes striking morphologic changes in subconfluent human colonic epithe

123 ly E11-14, which coincides with the onset of morphologic changes in telencephalic RG; (2) at E15-16,

124 Morphologic changes in the cells were also examined.

125 Ciliary body PDT resulted in morphologic changes in the ciliary body, significant red

126 id (FA) synthesis causing chronic stress and morphologic changes in the ER.

127 iod including increased serum creatinine and morphologic changes in the graft including interstitial

128 binding activity and resulted in remarkable morphologic changes in the heart of the transgenic mice.

129 type III LTPs produced microscopy-observable morphologic changes in the intine underneath the exine (

130 atency and intrahepatic portal branches, the morphologic changes in the liver, the presence of hepati

131 Imaging of DeltaPsi(m) revealed morphologic changes in the mitochondria after depolariza

132 omprehensive cross-sectional analysis of the morphologic changes in the peritoneal membranes of patie

133 Initial morphologic changes in the process of cell death were cy

134 hat gonadal hormonal manipulation results in morphologic changes in the rat hippocampus.

135 n did not reveal any overt toxicity or gross morphologic changes in the retina.

136 Morphologic changes in the retinal pigment epithelium (R

137 polarization-sensitive OCT revealed specific morphologic changes in the RPE and outer retinal layers

138 Morphologic changes in the small intestine and colon wer

139 Loss of receptor resulted in morphologic changes in the stroma, including changes in

140 ortisol acetate showed steroid glaucoma-like morphologic changes in the TM that correlated with the i

141 ence and immunohistochemical analyses imaged morphologic changes in the tumor blood-brain barrier mic

142 y and vascular permeability may occur before morphologic changes in the vasculature.

143 in activated microglia (increased number and morphologic changes) in the periventricular region and h

144 induced a dose-dependent gradual increase in morphologic changes; in contrast, EPO and EDN induced mi

145 A resulted in increases in sphingomyelin and morphologic changes including increased epidermal lipid

146 Morphologic changes, including morphologic patterns, and

147 s prepared for transplantation undergo rapid morphologic changes, including retraction of axon termin

148 that the exogenous MUC13 expression induced morphologic changes, including scattering of cells.

149 Various morphologic changes, including whitening of the treated

150 t that reduced expression of PDEF leads to a morphologic change, increased migration and invasiveness

151 inal granulocytic differentiation, including morphologic changes, increased CD11b/CD66b expression, a

152 tificial surfaces, underwent biochemical and morphologic changes indicative of a potentiated state, i

153 hese cells Fas oligomerization triggered the morphologic changes indicative of apoptosis regardless o

154 alyzes exchange for RhoA, but does not cause morphologic changes indicative of RhoA activation.

155 The HCT-8 organoid displayed morphologic changes indicative of successful and quantif

156 hibitor decreased cell viability and induced morphologic changes indistinguishable from those caused

157 activity and the increased proliferation and morphologic change induced by TGF-beta in vitro.

158 ect than wild-type PAK5, indicating that the morphologic changes induced by PAK5 are directly related

159 The morphologic changes induced by reduction of blood flow w

160 f the KCL22 blast cells occurred as shown by morphologic changes, induction of expression of CD11b, p

161 surface of transfected cells, and that this morphologic change is similarly PH domain dependent.

162 This morphologic change led to the excision of the lesion.

163 Visual acuity and morphologic changes measured on SD-OCT.

164 ular matrix-derived signals lead to critical morphologic changes mediated through cytoskeletal rearra

165 The morphologic changes most likely reflected interference o

166 ithelial cells (podocytes) undergo extensive morphologic changes necessary for creation of the glomer

167 that modulation of activity may play in the morphologic changes observed after reducing cortical 5-H

168 ed by cell viability, DNA strand breaks, and morphologic changes observed by transmission electron mi

169 ut mice from birth until 3 wk, preceding the morphologic changes observed in the hair follicles.

170 phenol in human melanocytes, as well as with morphologic changes observed in this study in cells expo

171 The molecular and morphologic changes observed in young BBS animal model e

172 However, distinct morphologic changes occur with injury that appear to com

173 However, the morphologic changes occurring in response to BFT are dep

174 6, and 18 h in culture, and examined for the morphologic changes of apoptosis and viability by fluore

175 strand breaks, a later step in a sequence of morphologic changes of apoptosis process.

176 tivation, DNA fragmentation, and the classic morphologic changes of apoptosis.

177 n death in male mice accompanied by loss and morphologic changes of cardiac mitochondria and down-reg

178 IVCM reveals an increased density and morphologic changes of central epithelial DCs in infecti

179 Morphologic changes of concern for neoplasm were present

180 d constitutively activated Mek or Erk showed morphologic changes of differentiation.

181 Typical morphologic changes of ER stress preceded development of

182 Apoptosis was assessed hourly by nuclear morphologic changes of fixed cells by DAPI fluorescence

183 ter transplantation and were associated with morphologic changes of focal segmental glomerulosclerosi

184 This study examines morphologic changes of glial cells in the retinas of gla

185 To examine whether S1P contributes to the morphologic changes of islets via S1P2, the receptor ant

186 Ectopic expression of TMEM106B induces morphologic changes of lysosome compartments and delays

187 permeability, vascular lesions, leukostasis, morphologic changes of micro- and macroglia, apoptosis,

188 atment significantly reduced the severity of morphologic changes of OA compared with placebo.

189 with and without TGF-beta1 inhibitor, on the morphologic changes of primary culture of hGE cells were

190 The angle and morphologic changes of the PCL are age dependent through

191 vity within an inflamed arterial wall before morphologic changes on other imaging studies.

192 diation creates a characteristic spectrum of morphologic changes on the porcine corneal stromal surfa

193 teristics such as the presence or absence of morphologic changes or accompanying findings (including

194 Simvastatin did not cause morphologic changes or cytotoxicity in the fibroblasts,

195 veforms, and their retinas had no detectable morphologic changes or loss of cells.

196 ction, recipients developed proteinuria with morphologic changes (podocyte effacement), a condition t

197 The p38 inhibitor blocked only the morphologic changes produced by TNFalpha.

198 photosensitizers that elicits no significant morphologic changes produces transient and recoverable r

199 emory T cell and alloantibody response, with morphologic changes reflecting antibody-mediated allogra

200 esulted in the epithelial-to-fibroblast-like morphologic changes reported by others and in the decrea

201 The metabolic and morphologic changes resulting from activation of the str

202 d outer nuclear membranes reminiscent of the morphologic changes seen in cells productively infected

203 ulation appears closely related to the other morphologic changes seen in patients with EoE.

204 In our series, we attempted to analyze the morphologic changes seen in the optic disc pit and evalu

205 stly, we demonstrate partial reversal of the morphologic changes seen within the afferent IHC ribbon

206 cells undergo an aging program that includes morphologic changes, sterility, redistribution of the Si

207 c protein 26 (MIP26), CP49, and filensin and morphologic changes such as cell multilayering and elong

208 The proportion of patients showing retinal morphologic changes, such as intraretinal cysts (IRCs),

209 al changes coupled with a lack of detectable morphologic changes suggest that ANT1 is not essential f

210 ssays were used to confirm the nature of the morphologic changes that accompany growth factor stimula

211 th primary myelofibrosis show functional and morphologic changes that are associated to the mesenchym

212 ows for an examination of the retina's early morphologic changes that are not generally visible with

213 Astrocytes in the glial lamina showed morphologic changes that correlated with the severity of

214 c deletion of Klf5 in adult mice resulted in morphologic changes that included a regenerative phenoty

215 plementary information about biochemical and morphologic changes that occur during the development of

216 Morphologic changes that occur with deletion of Klf5 are

217 sequestration, induced immunophenotypic and morphologic changes that paralleled CI treatment.

218 ma xenografts exhibit increased invasion and morphologic changes that resemble human large cell anapl

219 ular necrosis does not actually manifest the morphologic changes that the name implies.

220 , Schiff reagent, and fluorescein, to assess morphologic changes, the presence of goblet cells, and b

221 ccumulation, even at doses too low to effect morphologic changes; the initial (first 48 hours), gradu

222 the time course of chemotherapy and precede morphologic changes, these results suggest that the APT

223 HIV/SIV infection in spleen and in promoting morphologic changes through the loss of specific macroph

224 The morphologic changes, time of onset, and percentage of an

225 proximal femur was used to determine whether morphologic changes to the bone could be quantified and

226 optosis in hRPE, indicated by characteristic morphologic changes; TUNEL-positive labeling; phosphatid

227 All dogs showed gross morphologic changes typical of OA in the unstable knee.

228 tem make it a likely candidate for mediating morphologic changes typically seen in the epileptic hipp

229 enic patients to determine whether there are morphologic changes underlying these cognitive deficits.

230 ressing Box3-deficient gp130 showed distinct morphologic changes upon receptor activation.

231 Interobserver agreement for scoring morphologic changes was good among 3 radiologists (kappa

232 Cell morphologic changes were accompanied by decreased epithe

233 These noladin ether-induced morphologic changes were also blocked by SR141716A and P

234 Morphologic changes were assessed before and after anti-

235 At day 21, morphologic changes were assessed by immunohistochemistr

236 Morphologic changes were assessed by light microscopy at

237 In neurons that were dying by apoptosis, morphologic changes were characterized by a highly order

238 These morphologic changes were closely correlated with a decre

239 Morphologic changes were completely inhibited by treatme

240 as 0.5 pM could also cause intoxication, but morphologic changes were detectable only when the assay

241 dystrophic, with disrupted lens, whereas no morphologic changes were detected in the eyes of the oth

242 Cellular morphologic changes were evaluated by electron microscop

243 These morphologic changes were independent of hTR expression a

244 Morphologic changes were observed in photoreceptor sheet

245 f plasminogen and plasminogen activator, and morphologic changes were observed using scanning electro

246 These morphologic changes were partially reversed by RbAp48 kn

247 Lens histologic and morphologic changes were recorded microscopically.

248 No RD and minimal morphologic changes were seen in the eyes injected with

249 The functional and morphologic changes were studied chronologically (from 1

250 latelets undergo a series of actin-dependent morphologic changes when activated by thrombin receptor

251 ted with the B. fragilis toxin (BFT) develop morphologic changes with dissolution of tight clusters a

252 to E8.5), when the conceptus undergoes rapid morphologic changes with formation of the yolk sac and b

253 mplete media to nonselective media displayed morphologic changes with static growth.

254 face contracted and underwent characteristic morphologic changes with the applied thermal load, which

255 Gene expression profiles parallel cell-morphologic changes with time, ultimately leading to inc