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1 ugh during which fadeout of transmission was most likely.
3 catalysis of periplasmic transaminations is most likely a general tool for specific biosynthetic pat
5 haped by an extensive genome duplication or, most likely, a whole-genome duplication (WGD), which is
7 ab35 as a novel regulator of WPB exocytosis, most likely acting through the downstream effectors ACAP
9 Our observations identified those mutations most likely amenable to pharmacological rescue in the af
14 served coherence of these quasi-bound states most likely arises from phase- and frequency-synchronize
15 iffer for G4 disruption and dsDNA unwinding, most likely arising from differences in the rate-limitin
16 trong diagnostic evidence that this outbreak most likely arose from unvaccinated or under-vaccinated
17 ater, its binding leads to mRNA destruction, most likely as a consequence of translational repression
18 rphology and capacity of autonomous selfing, most likely as a way to reduce the probability of inters
19 of AnkB-Paris is indispensable for function; most likely as an ER retention motif that enables anchor
20 ne in mice decreased the liver levels of RE, most likely as the result of a gradual disappearance of
21 are clinically relevant peanut allergens and most likely associated with severe allergic symptoms.
23 owever, this same processing technique could most likely be applied to any low photon-number image ir
24 perdeuterated acetone is observed, which can most likely be attributed to the exchange of a methyl gr
25 aloforms through trihaloacetyl compounds can most likely be extended to other ecosystems with organic
27 HOBTB2 was more abundant than the wild-type, most likely because of impaired degradation in the prote
28 metastases < 1.0 cm were (18)F-FET-negative, most likely because of scanner resolution and partial-vo
30 nt mutants emerged in vitro but not in vivo, most likely because resistant mutations affected bacteri
31 SQE2, alpha-onocerin production was boosted, most likely because the epoxidases produce higher amount
32 equirement for CDK6 but not CDK4 expression, most likely because, in these cells, CDK6 was predominan
33 cules (88%) were immobile, with the molecule most likely being physisorbed or trapped; the remainder
34 cording assays, we found that an RNA aptamer most likely binds to the receptor's regulatory site and
35 uced production of proinflammatory cytokines most likely by activation of the adenosine A2a receptor.
37 cally inhibited elongation of Abeta fibrils, most likely by binding to the ends of growing fibrils.
38 D substitution disrupted catalytic activity, most likely by causing an electrostatic perturbation at
39 genesis of PA14 during burn wound infection, most likely by contributing to PA14 survival in the bloo
40 ates both the ImAHP and IsAHP in OT neurons, most likely by controlling Ca(2+) entry through voltage-
41 ting NBs play a role in infection processes, most likely by enabling pathogens to outcompete commensa
42 hibited CXCR4 phosphorylation and signaling, most likely by functioning as a nonspecific CXCR4 antago
44 rotect mice from severe influenza infection, most likely by reducing TLR4-dependent cytokine storm me
47 ceptor ciliogenesis and retinal development, most likely by trafficking cilia and outer-segment prote
48 lic acids with molecular weight (MW) 216 Da (most likely C10H16O5) and MW 214 Da (C10H14O5) was confi
57 ns and modeling at the site suggest that the most likely cause of the decrease in MS is the transform
59 al (product of glutathione and MG), which is most likely caused by S-nitrosylation of aldose reductas
60 The absence of the other two decorations is most likely caused by the downregulation of phoPQ and pm
61 The results showed that the H7N8 LPAI virus most likely circulated among diving ducks in the Mississ
66 aptive immunity by depletion of CD4 Th cells most likely contributes to loss of immune control of LTB
67 boundary subdomains between petal primordia, most likely contributing to formation of congenitally fu
68 er beetles), that had an earlier gymnosperm (most likely cycad) host association, later transitioning
69 ted by tricarboxylic acid cycle metabolites (most likely depending on the amino-terminal region aroun
70 idest diversity and may indeed represent the most likely descendants of the populations responsible f
71 iastereoselective total synthesis of the two most likely diastereomeric candidates for the structure
72 hypothesis significance tests and select the most likely differentially abundant proteins with a corr
73 ly available data shows these candidate SNPs most likely do not have biochemical function; only 13% o
76 d in misregulation of defense-related genes, most likely due to decreased H3K9 acetylation levels at
77 ently entirely by overcoming these defences, most likely due to elevated oxidative stress resistance.
78 maining uncleared savannas of South America, most likely due to fire suppression and land fragmentati
79 an alternative in vivo reconstitution path, most likely due to greater protein oligomerization from
80 and 7q- developed myelodysplastic syndrome, most likely due to haploinsufficiency of related 7q21.2
81 potentially resulting in improved survival, most likely due to increased mitochondrial respiratory c
83 evidence of fine-scale genetic structuring, most likely due to limited seed dispersal, but the overa
85 nd ILC2 responses were observed in the lungs most likely due to oxidative stress caused by neonatal h
86 tal distribution and uptake of the Zn forms, most likely due to rapid dissolution of the ZnO NPs.
87 ity in women from industrialized settings is most likely due to reverse causation: Poverty reduces ag
88 The use of hamsters has declined, however, most likely due to the dearth of genetic tools available
89 e many mechanisms to aid in protein folding, most likely due to the need for most chaperones to bind
92 ainted meat in cold meat products, which was most likely due to the serving temperature on the one ha
93 ion) using trisodium citrate as draw solute, most likely due to the unique swelling behavior of the p
95 howed that the ancestor of all ST8 S. aureus most likely emerged in Central Europe in the mid-19th ce
98 in hatcheries has often been invoked as the most likely explanation for reduced fitness, and most st
99 Based on our analysis, the mathematically most likely explanation for the renewed growth in atmosp
100 rature-sensitive (ts) phenotype, providing a most likely explanation for the stronger attenuation obs
103 The expert panel concluded that (a) the most likely explanation of available evidence from outbr
104 malities including microcephaly, and (b) the most likely explanation of available evidence from outbr
108 s with diabetes living in tropical countries most likely face increased risks of common and health-ca
109 bservations, we hypothesize that trastuzumab most likely fails in the treatment of brain metastases o
110 ental results indicate that NiHi defects are most likely formed and these defects do not introduce de
111 onsistent with influxes of non-local people, most likely from northern Eurasia and the Pontic Steppe.
113 h is consistent with multiple introductions, most likely from the northern states of Brazil, and with
114 absorption by its FAD chromophore, which is most likely fully oxidized (FADox) in the dark state and
115 oritization approach revealed rs10995 as the most likely functional single-nucleotide polymorphism, a
117 murine LRT and we provide evidence that PlrS most likely functions via the putative cognate response
118 circulating primary HIV-1 strains, a vaccine most likely has to induce broadly neutralizing antibodie
119 istic model to assign mapping results to the most-likely IDs, (iii) comprehensive ribosomal RNA filte
120 ed global flexibility of the Val-213 variant most likely improve its local availability and reduce th
121 nd reliable signal of early flooding stress, most likely in tight interaction with the other gases.
123 modeling revealed that Cd removal processes most likely increased in magnitude substantially between
125 decreased during atDCS compared with stDCS, most likely indicating augmented efficiency in brain net
126 innate immune activators and that the miRNAs most likely induce cytokine production and leukocyte mig
128 G121 RNA signals through TLR13; however, the most likely intracellular receptor in human subjects is
131 that Spanish teosinte is of admixed origin, most likely involving Zea mays ssp. mexicana as one pare
132 FL-AE crystal structure reveals Na(+) as the most likely ion present in the solved structures, and pu
133 The cause of ice expansion is uncertain, but most likely it is related to increased atmospheric tempe
135 at the sensory photoreceptor ribbon synapses most likely lack RIM1 and predominantly express RIM2 var
136 ent toward the center of the pore region and most likely lead to disturbance of the gating mechanism.
137 mbia which suggests that the attack rate was most likely less than 50%; and 32.4% (95% CI: 2.5-94.2%)
138 a topic of discussion and interest, with the most likely levels of least resistance being the interdi
139 We find that [Formula: see text] increases (most likely linearly) with magnetic field H and saturate
140 entation, or some combination of the two and most likely made the species even more susceptible to la
141 ved tumor targeting (biodistribution) as the most likely mechanism of AR160 therapeutic superiority o
144 e parental differentially methylated regions most likely mediate the remodeling of methylation and tr
148 eiotropic effects in the mutated library are most likely minimized because only one gene was mutated
150 ration behavior together with accurate mass, most likely molecular formula, as well as MS/MS as requi
151 imated clonality of mutations determined the most likely MSI target genes to be the aminoadipate-semi
152 s, suggesting that, while these proteins are most likely nitrate/nitrite antiporters, they can also a
153 -length peripherin-2/rds, partitioning would most likely occur at a bilayer interfacial region, poten
154 in of this highly deviant chloroplast genome most likely occurred before the emergence of the Cladoph
155 olic Naa60 anchoring to the Golgi apparatus, most likely occurring post-translationally and specifica
156 d television consumption, after sex, was the most likely of these predictors to contribute to variati
158 Micromagnetic simulations suggest that the most likely origin is an unintentional shape anisotropy.
159 V-6B in many carriers with European ancestry most likely originated from ancient integration events i
160 r M. elongata - M. cysteinexigens symbiosis, most likely over 350 million years ago and concomitant w
161 ents to interpret BCID results, identify the most likely pathogen, and then choose therapy based on t
164 che modeling indicated that changing climate most likely played a role in the decline of the Sumatran
165 Here, cyclin C-Cdk8 phosphorylation of Med13 most likely primes the phosphodegron for destruction.
166 ficantly reduced in affected fibroblasts and most likely produces a truncated protein (p.Val351Glyfs(
172 maturation pattern and extended brain growth most likely reflect Neandertal physiology and ontogeneti
173 the carbonate record after 3.1 ka therefore most likely reflect the historical variation in hydrothe
175 ations of PAHs increased from south to north most likely related to a combination of coal-eroding bed
178 substrates compared with native proteins is most likely related to the reduced accessibility of the
179 ata, our approach revealed subjects that are most likely related, but had previously passed standard
183 Passive immunotherapy against HIV-1 will most likely require broadly neutralizing antibodies (bnA
184 diminished motor activity of this mutant is most likely responsible for impaired hearing in the shak
185 oss the proteome and identification of those most likely responsible for the functional consequences
186 onins, flavonoids, and terpenoids, which are most likely responsible for their biological activity.
191 inating from and hosted by wild animals, are most likely shaped by commensalism related to human acti
192 ween cell infection and viral production, is most likely short ( approximately 4 h), the median withi
193 lead-rich crystal termination planes are the most likely sites for electron trapping and thus nanomet
195 oupled nitrification of newly fixed N is the most likely source of nitrogen oxides supporting nitrous
196 nfections with high parasite numbers are the most likely source of resistance emergence, so effective
198 mate Bayesian computation suggested that the most likely speciation scenario explaining this pattern
201 he sigma receptor lead to oxidative species (most likely superoxide) that in turn oxidize VMAT2.
203 nds and seasonally inundated floodplains are most likely the controlling sources of atmospheric metha
204 a mixture of conformations, one of which is most likely the open-X structure which has unpaired base
206 onditions, this methane is not a remnant but most likely the result of ongoing leakage from the reser
207 binds a quaternary polysaccharide structure, most likely the triple helix adopted by polymerized beta
209 nduced shift from cognitive to habit memory, most likely through altered crosstalk between the hippoc
211 rleukin (IL)-6 (0.3-fold of control, p<0.1); most likely through enhancing glutathione peroxidase (GP
212 NS1) of WNV antagonizes IFN-beta production, most likely through suppression of retinoic acid-inducib
213 correctly allocates cells into the autopod, most likely through the control of cell-surface properti
215 mple clinical method to identify individuals most likely to accrue the largest benefit from continued
216 es, namely that the small molecules that are most likely to accumulate contain an amine, are amphiphi
217 ents with severe eosinophilic asthma who are most likely to achieve clinically significant reductions
221 Understanding which species and habitats are most likely to be affected is critical for adaptive mana
223 tion strategy to identify which findings are most likely to be genuine, and hence worthy of further s
225 nd this gene regulatory function of ADARs is most likely to be of high biological importance beyond t
226 xpertise regarding articles we believed were most likely to be of high clinical and scientific import
227 th AD with generalized distribution were the most likely to be patch tested (OR, 4.68; 95% CI, 3.50-6
228 luate which hydrolysis reaction pathways are most likely to be relevant for organic chemicals found i
229 s measure and report those outcomes that are most likely to be relevant to users of their research.
231 100 M. tuberculosis strains either least or most likely to be transmitted after controlling for host
234 allow the therapy to be targeted to patients most likely to benefit and not experience serious advers
235 veloping methods for targeting LTFU patients most likely to benefit can make this practice more effic
236 Baseline biomarkers can identify subjects most likely to benefit from adjunctive therapy with omal
238 l improve identification of patients who are most likely to benefit from drug treatment to prevent fr
239 Our findings could help identify patients most likely to benefit from IMiDs and suggest direct Trx
240 surement of which can help identify patients most likely to benefit from inhaled corticosteroids and
241 (ICH) expansion and may mark those patients most likely to benefit from intensive blood pressure (BP
244 needed to aid with the selection of patients most likely to benefit from stress testing after PCI.
246 demonstrated utility in identifying patients most likely to benefit from targeted anti-interleukin an
247 eful for identifying the individuals who are most likely to benefit from targeted neurostimulation th
248 n, further evidence on the types of patients most likely to benefit from the use of ezetimibe in addi
249 y enabling identification of patient subsets most likely to benefit from therapies predicated on mani
250 u hybridisation (FISH) can identify patients most likely to benefit from these drugs combined with ch
251 O2 pathway analysis could identify patients most likely to benefit from treating a specific defect;
253 to enrich the study population with patients most likely to benefit, based on predicted patient respo
259 alizumab to facilitate selection of patients most likely to derive the greatest clinical benefit from
260 y shared the larvae type that their mate was most likely to desire and also increased the quantity of
262 ts with pneumonia + acute kidney injury were most likely to die or reach major adverse kidney events.
266 However, to our knowledge, the patients most likely to experience a significant response to ther
268 yped features of neuronal circuits are those most likely to explain the remarkable capacity of the br
269 45 of CcmH and Cys-34 of apocytochrome c are most likely to form this mixed disulfide bond, which is
271 ve appointment waiting times of 2-3 days the most likely to have patients who serially miss appointme
273 leep, a period when these abnormalities were most likely to interfere with memory consolidation.
274 mical volatiles emitted by bacteria that are most likely to mediate bacterial or plant responses to B
275 model can identify vector control strategies most likely to minimise the spread of insecticide resist
277 ibution patterns when the passage of ECEs is most likely to occur from 2012 to 2016 using passive aco
278 ntly change axonal conduction properties are most likely to occur over timescales of days to weeks.
279 edicts that abrupt biodiversity declines are most likely to occur when habitat availability is reduce
280 ocessing are strikingly altered by attention most likely to optimally achieve the behavioral goal.
281 n algorithm to predict the types of N-glycan most likely to predominate at all the putative N-glycosy
282 ast likely to receive a transplant, patients most likely to receive a transplant were more likely to
287 rger cohort of patients might identify those most likely to respond to this chemoimmunotherapeutic re
294 s a specialized MHC class I molecule, and is most likely transported to the cell surface only when su
295 anotransduction [5], and/or proteolysis [6], most likely under the control of transcriptional program
296 amic causal modeling to demonstrate that the most likely underlying neural network consisted of a pul
297 ndeed derived from the external environment, most likely via a conversion catalyzed by one or more 17
298 tween cognitive and habitual memory systems, most likely via altered amygdala orchestration of these
299 that atypical E2Fs act as tumor suppressors, most likely via transcriptional repression of cell cycle
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