ライフサイエンスコーパス: mother cell

1 nd thereby promotes their confinement in the mother cell.

2 ges de novo from a morphologically invariant mother cell.

3 ion in the cell lineage leading to the guard-mother cell.

4 is engulfed by the membrane of the adjacent mother cell.

5 , including protein aggregates, to the aging mother cell.

6 dissection of daughter cells from the larger mother cell.

7 yielding the smaller prespore and the larger mother cell.

8 ion of the growth and DNA replication of the mother cell.

9 gth correlates with chromosome number in the mother cell.

10 f two spores (twins) forming within the same mother cell.

11 cells are formed within the cytoplasm of the mother cell.

12 owed by activation of sigma(E) in the larger mother cell.

13 block the DNA replication and growth of the mother cell.

14 gely absent from the SPB that remains in the mother cell.

15 properties before they are released from the mother cell.

16 which separate it from the cytoplasm of the mother cell.

17 uires expression of the spoIIIA locus in the mother cell.

18 l transduction between the forespore and the mother cell.

19 orespore) is wholly engulfed by the adjacent mother cell.

20 A circles, which act as aging factors in the mother cell.

21 rotein aggregates and their retention in the mother cell.

22 cell wall degradation protein complex in the mother cell.

23 mal layer differentiating into the megaspore mother cell.

24 nstituents and prolonged the lifespan of the mother cell.

25 ir length roughly equals the diameter of the mother cell.

26 ructures that had a strong bias to remain in mother cells.

27 on of INPs into terminally dividing ganglion mother cells.

28 which is highly up-regulated in their pollen mother cells.

29 with the Olig2(+) cells behaving as ganglion mother cells.

30 directed gene expression was enhanced in the mother cells.

31 stributed unequally between the daughter and mother cells.

32 h multiple buds, several SPBs and binucleate mother cells.

33 G1 variability in daughter cells but not in mother cells.

34 is physically distinct from mitochondria in mother cells.

35 ansmits the longevity benefit of CR to moved mother cells.

36 undergo continuous movement from buds toward mother cells [1].

37 septum that separates the forespore from the mother cell, a process that depends on the autolysin Spo

38 bias' (preferential plasmid retention in the mother cell) according to binomial distribution, thus li

39 although vacuolar acidity is reduced in aged mother cells, acidic vacuoles are regenerated in newborn

40 t were both long-lived and retained in aging mother cells after approximately 18 cells divisions.

41 Replicative aging in yeast is asymmetric-mother cells age but their daughter cells are rejuvenate

42 tivation (ETI), yeast cells have accelerated mother cell aging and mildly perturbed cell cycles.

43 The acceleration of ETI mother cell aging was not explained by increased reactiv

44 evidence that asymmetric distribution drives mother cell aging.

45 altered cell-cycle dynamics, and accelerated mother cell aging.

46 Despite the gradual aging of the mother cell, all daughters are born rejuvenated and enjo

47 Investigation in meiosis using pollen mother cells also revealed that it is not the major comp

48 Using single budding yeast mother cell analyses we found that, even early after tel

49 Cells in which both mother-cell anchoring mechanisms have been disabled have

50 s in asymmetric prion distribution between a mother cell and a bud.

51 n asymmetric cell division, creating a large mother cell and a small forespore.

52 to develop into two different cell types, a mother cell and a spore.

53 lly, SpoIIGA is predominantly located in the mother cell and as a consequence confines sigma(E) activ

54 Kin4 primarily localizes to the mother cell and associates with spindle pole bodies (SPB

55 ptc1Delta cells, ER tubules migrate from the mother cell and contact the bud tip, yet fail to spread

56 a multimeric membrane complex connecting the mother cell and developing spore that is required to mai

57 envelope secretion complex that connects the mother cell and developing spore.

58 Recent experiments indicating that the mother cell and forespore are joined by a channel have l

59 that the ctpB gene is expressed in both the mother cell and forespore compartments but that synthesi

60 passage of large macromolecules between the mother cell and forespore during the feeding process.

61 specialized secretion system that links the mother cell and forespore has a complexity approaching t

62 ture, it may also form a channel between the mother cell and forespore membranes.

63 proteins secreted into the space between the mother cell and forespore membranes.

64 -Q complex and a hub for the localization of mother cell and forespore proteins.

65 cent cells of the developing sporangium, the mother cell and forespore.

66 complex contains a conduit that connects the mother cell and forespore.

67 cross the double membrane that separates the mother cell and forespore.

68 an SPB escapes the MEN inhibitor Kin4 in the mother cell and moves into the bud where the MEN activat

69 D is a key regulator of transcription in the mother cell and positively or negatively regulates more

70 ls divide asymmetrically, generating a large mother cell and smaller forespore.

71 lized, with different genes expressed in the mother cell and the forespore.

72 ranes to create a direct conduit between the mother cell and the forespore.

73 roximately equal numbers of molecules in the mother cell and the forespore.

74 was nearing completion, when one was in the mother cell and the other in the prespore.

75 It yields two unequal cells, the mother cell and the prespore, and septum formation is co

76 Thus, only when a MEN bearing SPB leaves the mother cell and the spindle is accurately positioned alo

77 , defined sets of neuroblasts, many ganglion mother cells and discrete populations of neurons.

78 hat acidity of the vacuole declines in aging mother cells and limits lifespan, but that daughter cell

79 spond to transient DNA replication stress in mother cells and that a lack of telomerase accelerates o

80 in order to distinguish active and inactive mother cells and the behaviors of their daughter nuclei

81 eservoir of high-functioning mitochondria in mother cells and thereby preserves maternal reproductive

82 asymmetric cell division, leading to a large mother-cell and a small forespore compartment.

83 ate that GerM and SpoIIIAH, derived from the mother cell, and SpoIIQ, from the forespore, have recipr

84 s during the early asymmetric divisions of a mother cell, and that preventing this decline suppresses

85 uses accumulation of circles and NPCs in the mother cell, and thereby promotes ageing.

86 omere length, finite replicative lifespan of mother cells, and survivorship.

87 termines how the cytoplasmic contents of the mother cell are partitioned into the daughter cells, and

88 ulate mitochondria in daughter buds and that mother cells are frequently devoid of all mitochondria.

89 ed a replicative longevity paradigm in which mother cells are moved after 15 generations on defined m

90 ess-response proteins Pdr5p and Trx2p in the mother cells are stable during the first few cell cycles

91 takes place in the terminally differentiated mother cell as offspring grow.

92 n yeast, partitioning of such circles to the mother cell at mitosis ensures their loss from the popul

93 iming to facilitate SYS-1 clearance from the mother cell at the time of asymmetric division.

94 Mother cells bearing twins are substantially longer than

95 s into the endospore, while the larger cell (mother cell) becomes a terminally differentiated cell th

96 ng spore just as forespore engulfment by the mother cell begins.

97 cerevisiae cells divide asymmetrically: the mother cell buds to produce a smaller daughter cell.

98 Pma1 accumulates in aging mother cells, but is largely absent from nascent daughte

99 Cytosolic pH increases in aging mother cells, but is more acidic in daughter cells.

100 es that induce ER stress are retained in the mother cell by activation of the ER Stress Surveillance

101 d as pro-sigma(E), which is activated in the mother cell by cleavage in response to a signal from the

102 e SpoIIGA to activate sigma(E) in the larger mother cell by processing of pro-sigma(E).

103 candidates to be long-lived and retained in mother cells by time-lapse microscopy.

104 in silencing is reported to decline in aging mother cells, causing sterility in old cells.

105 and gerO and gerQ were expressed only in the mother cell compartment during C. perfringens sporulatio

106 and spoVE gene products are expressed in the mother cell compartment early during sporulation and pla

107 he regulation of developmental events in the mother cell compartment of C. perfringens is not the sam

108 ma(F) activation, sigma(E) activation in the mother cell compartment only occurs above the KinA thres

109 e anaphase spindle becomes misaligned in the mother cell compartment, cells arrest in anaphase becaus

110 If the spindle becomes mispositioned in the mother cell compartment, cells arrest in anaphase due to

111 In the absence of MciZ, the mother-cell compartment of the sporangium aberrantly for

112 is, sigma(E)-directed gene expression in the mother-cell compartment of the sporangium triggers the a

113 a(F) in the forespore and of sigma(E) in the mother cell compartments occurs via a cascade of coheren

114 differentially localize to the forespore and mother cell compartments of the sporangium during spore

115 fic protein degradation showed that only the mother cell complex is required to translocate DNA into

116 shape the cell plate as it grows toward the mother cell cortex is dependent upon a large array of pr

117 It was suggested that yeast mother cells could also differ from each other depending

118 BclA and BclB proteins are expressed in the mother cell cytoplasm and become spore-associated in a t

119 rane fission releases the forespore into the mother cell cytoplasm.

120 tex glia, and between NBs and their ganglion mother cell daughters.

121 e highly efficient trapping and retention of mother cells, determination of the replicative lifespan,

122 ed and expand, and lead to failure in pollen mother cell development.

123 f mitochondria accumulates at the tip of the mother cell distal to the bud.

124 on among the offspring was determined as the mother cell divides into daughter cells.

125 Only a tiny proportion of mother cell DNA is inherited by intracellular offspring,

126 ns provide a potential explanation for guard mother cell dormancy in soybean embryos.

127 o membranes to connect the forespore and the mother cell during endospore development in the bacteriu

128 part of the exosporium assembled within the mother cell during sporulation and the only part of the

129 ther to confine protein deposit formation to mother cells during division.

130 hat daughter cells receive mitochondria from mother cells during division.

131 Like their mother cells, EMP expressed molecules important for Ag p

132 eted and the dividing septum is thinned, the mother cell engulfs the forespore in a slow process base

133 During development the mother cell engulfs the forespore to produce a protoplas

134 Following asymmetric division, the mother cell engulfs the forespore, surrounding it with t

135 , we investigate the mechanisms by which the mother cell engulfs the prospective spore during sporula

136 sexual reproduction initiates with megaspore mother cell entry into meiosis and formation of a tetrad

137 teracts across an intercellular space with a mother cell-expressed membrane protein, SpoIIIAH.

138 monstrated that TEX1 repressed the megaspore mother cell fate by promoting the biogenesis of TAS3-der

139 the THO complex in restricting the megaspore mother cell fate to a single cell.

140 gametes arise via meiosis of diploid pollen mother cells followed by two rounds of mitotic division.

141 division and do not typically reoccupy their mother-cell footprint, and often even disseminate their

142 olarity is a key event in the preparation of mother cells for asymmetric cell divisions that produce

143 tion of mother cell membrane proteins to the mother cell-forespore interface.

144 In this study, we show that yeast mother cells form a protein aggregate during early repli

145 f ARF3 expression limits excessive megaspore mother cell formation non-cell-autonomously.

146 that SpoIIIE assembles a complex only in the mother cell, from which DNA is exported, but that DNA tr

147 ike a developmental checkpoint ensuring that mother cell gene expression does not commence unless mor

148 feedback by sigma(K) RNA polymerase on early mother cell gene expression is to lower the level of Spo

149 d in activation of later, sigma(K)-dependent mother cell gene expression results in decreased synthes

150 ngulfment is impaired and, as a result, late mother cell gene expression under the control of sigma(K

151 ctive sigma(K) RNA polymerase inhibits early mother cell gene expression, reducing accumulation of Sp

152 Here, the effects of perturbing the mother cell gene regulatory network by maintaining the S

153 During asymmetric division, a mother cell generates daughter cells that go on to adopt

154 Division of the asymmetrically growing mother cell gives rise to daughter cells that differ in

155 Asymmetric division, in which a single mother cell gives rise to daughters with distinct identi

156 We show that the mother cell gives rise to two sisters that participate e

157 A mother cell giving rise to offspring usually needs to ch

158 ll (SMC) divisions toward the adjacent guard mother cell (GMC) during stomatal development in maize (

159 g into the differentiating, smaller ganglion mother cell (GMC) where they are required for neuronal d

160 ll (SMC) divisions toward the adjacent guard mother cell (GMC), apparently under the influence of a G

161 s the identity of its daughter, the ganglion mother cell (GMC), the asymmetric division of the GMC an

162 e a larger neuroblast and a smaller ganglion mother cell (GMC).

163 Type I neuroblasts produce ganglion mother cells (GMCs) that divide once to produce differen

164 in neuroblasts generate a series of ganglion mother cells (GMCs) that each make two neurons (type I l

165 ions to produce a series of smaller ganglion mother cells (GMCs), which typically divide once to form

166 fate specification to daughters of ganglion mother cells (GMCs).

167 Artificial Spo0A activation blocked mother cell growth in the absence of sigma(E).

168 or sigma(G) to the action of sigma(E) in the mother cell, has remained mysterious.

169 Siblings within a mother cell have similar numbers of oriCs.

170 partitioning of molecules at cell division, mother-cell heterogeneity, and variation in cell-cycle p

171 ruction of a bud and its separation from the mother cell in Saccharomyces cerevisiae have provided fo

172 of excitatory neurons arising from the same mother cell in the developing neocortex serve as a subst

173 fates of sister cells arising from the same mother cell in the regeneration blastema.

174 notype at meiosis, but only in the megaspore mother cell in the sexual genotype.

175 embrane space that separates forespores from mother cells in endospore-forming bacteria.

176 We show that viability of mother cells in liquid culture is regulated by SIR2 and

177 e functionally segregated even within single mother cells in S. cerevisiae.

178 ng ageing are preferentially retained by the mother cell, in part through tethering to mitochondria,

179 Mother cells inheriting old poles are phenotypically dis

180 metric cell divisions in which the subapical mother cell inherits most of the vacuolar space and beco

181 a remarkable stability of growth whereby the mother cell inherits the same pole for hundreds of gener

182 llus subtilis cell-division inhibitor, MciZ (mother cell inhibitor of FtsZ), blocks assembly of FtsZ.

183 ges are generated by repeated divisions of a mother cell into a series of daughter cells, often with

184 ercellular channel allowing passage from the mother cell into the forespore of factors required for l

185 tes much of the circular chromosome from the mother cell into the forespore, but the molecular mechan

186 egulator of sigma(G) is transported from the mother cell into the forespore.

187 a regulated manner, to physically cleave the mother cell into two daughter cells.

188 It has been proposed that entry of mother cells into senescence is driven by the progressiv

189 Engulfment of the forespore by the mother cell is a universal feature of endosporulation.

190 orulation process, the inner membrane of the mother cell is inverted and transformed to become the ou

191 okinesis is the final step of mitosis when a mother cell is separated into two daughter cells.

192 ells so that the clonal marker of individual mother cells is traced in the specialized progeny.

193 ression of foxp3 epigenetically, which marks mother cell iTreg lineage choice within the genome of di

194 Our results demonstrated that QDs on mother cell landscape tend to distribute among its proge

195 nism ensuring that Kin4 only associates with mother cell-located SPBs.

196 The experiment reveals that CR mother cells lose the longevity benefit of CR when evacu

197 (MEP), an inducible genetic system in which mother cells maintain a normal RLS--a median of 36 gener

198 Each division redistributes the mother cell mass along the axis of division.

199 atchet" contributing to the migration of the mother cell membrane around that of the forespore in a p

200 Subsequently, the mother cell membrane engulfs the forespore in a phagocyt

201 The mother cell membrane protein SpoIIIAH recognizes the cel

202 he forespore membrane protein SpoIIQ and the mother cell membrane protein SpoIIIAH.

203 tional cue that dictates the localization of mother cell membrane proteins to the mother cell-forespo

204 IQ plays a central role in anchoring several mother-cell membrane proteins in the septal membrane.

205 isB-cardiolipin interactions ensure that the mother cell membranes are severed at the right time and

206 tion machines function as motors pulling the mother cell membranes around the forespore.

207 After division, the mother cell membranes migrate around the forespore in a

208 During sporulation in Bacillus subtilis, the mother cell membranes migrate around the forespore in a

209 pollen and seed sterility, altered Megaspore Mother Cell (MMC) specification, and delayed programmed

210 ivisions of stomatal stem cells (meristemoid mother cells [MMCs]) are fundamental for the generation

211 dozen transcripts that are exported from the mother-cell nucleus during mitotic anaphase, transported

212 f a channel or transporter through which the mother cell nurtures forespore development.

213 junction-like feeding tube through which the mother cell nurtures the developing spore by providing s

214 w studies indicate that retention of ERCs in mother cells occurs not by tethering to the nuclear peri

215 In the mother cell of sporulating Bacillus subtilis, a regulato

216 However, such defects are minor in mother cells of these mutants, likely because the G1 pha

217 increases the degree of reoccupation of the mother-cell outline in highly motile cells.

218 Yeast mother cells pay a sacrifice during budding: they keep t

219 ll GTPase RHO GTPASE OF PLANTS (ROP) promote mother cell polarity and subsequent division asymmetry i

220 suggest that PG degradation enables a second mother-cell-produced protein to interact with SpoIIQ.

221 e a finite replicative life span; that is, a mother cell produces only a limited number of daughter c

222 A yeast mother cell progressively ages with each cell division a

223 -dependent confinement of ER stress into the mother cell promoted aging.

224 gned spindle, mislocalization of Lte1 in the mother cell promoted loss of Bfa1 from one SPB and allow

225 ane protein SpoIIQ, which interacts with the mother cell protein SpoIIIAH at the septum to localize o

226 btilis, the forespore protein SpoIIQ and the mother cell protein SpoIIIAH form a channel, essential f

227 nism, strong ligand-receptor binding between mother-cell protein SpoIIIAH and forespore-protein SpoII

228 The forespore protein SpoIIQ and the mother-cell protein SpoIIIAH interact across the double

229 pads, used together to allow for trapping of mother cells, removal of daughter cells, monitoring grad

230 hracis spores nor the formation of spores in mother cells required UDP-GlcNAc 2-epimerase activity.

231 ntially eliminated from the forespore or the mother cell, respectively.

232 anaphase due to inhibition of the MEN by the mother cell-restricted SPoC kinase Kin4.

233 hat in the rts1 mutant, Ace2 accumulation in mother cells results in Ash1 expression in mothers, and

234 During vertical apical divisions, only the mother cell retained tight junctions and segregated apic

235 Alternation between DNA replication in the mother cell (S phase) and equal partitioning of the repl

236 We find that aged mother cells show a decreased ability to initiate the me

237 y after telomerase inactivation (ETI), yeast mother cells show transient DNA damage response (DDR) ep

238 Moreover, the elder mother cells showed lower coefficient of variation for P

239 it SpoIIIAH to the sporulation septum on the mother cell side; however, the mechanism by which SpoIIQ

240 it SpoIIIAH to the sporulation septum on the mother-cell side, however the mechanism by which SpoIIQ

241 pletion of engulfment of the prespore by the mother cell, sigma(G) is activated in the prespore.

242 sigma(K) activation and was thought to be a mother cell signal.

243 calized CDKG1 in pre-mitotic cells is set by mother cell size, and its progressive dilution and degra

244 of cell division may provide a link between mother cell-size and mitotic division number.

245 sion, wherein a 'counting' mechanism couples mother cell-size to cell division number allowing produc

246 es the polarization of asymmetric subsidiary mother cell (SMC) divisions during stomatal development.

247 that promotes the polarization of subsidiary mother cell (SMC) divisions toward the adjacent guard mo

248 es the polarization of asymmetric subsidiary mother cell (SMC) divisions toward the adjacent guard mo

249 vely to polarize the divisions of subsidiary mother cells (SMCs) during stomatal development in maize

250 Expression of mother cell-specific (spoIIID) and forespore-specific (s

251 e impaired in post-engulfment, forespore and mother cell-specific gene expression, suggesting a chann

252 spore-specific sigma factor sigma(F) and the mother cell-specific sigma factor sigma(E).

253 ative gene expression analyses of the pollen mother cell stage in seven diploid sexual and seven dipl

254 tal differentiation is arrested at the guard mother cell stage.

255 The mother cell subsequently engulfs the prespore.

256 to the formation of supernumerary megaspore mother cells, suggesting that TEX1- and TAS3-mediated re

257 part of a channel between the forespore and mother cell that is required for the activation of sigma

258 The few aged mother cells that do enter meiosis complete this develop

259 e report that formation of tubular ER in the mother cell, the first step in ER inheritance, depends o

260 gnificantly improved retention rate of yeast mother cell, the HYAA-Chip was capable of demonstrating

261 The MEN inhibitory zone is located in the mother cell, the MEN-activating zone in the bud, and the

262 lineage, known as meristemoids, and in guard mother cells, the progenitors of stomata.

263 functions in the activation of sigmaE in the mother cell; the other (SpoIIIL) is required for sigmaG

264 fate of QDs on molecular landscape of single mother cell through several generation times (progeny ce

265 that extend from the bud tip or neck to the mother cell tip, serve as tracks for bidirectional cargo

266 tory proteins control gene expression in the mother cell to ensure proper spore formation.

267 th spindle pole bodies (SPBs) located in the mother cell to inhibit MEN signaling.

268 stable through cell divisions, from a single mother cell to its progeny during mitosis, and represent

269 asmic protein aggregates are retained in the mother cell to protect the functional capacity of daught

270 ptor Vac17 to transport the vacuole from the mother cell to the bud.

271 and terminates organelle transport from the mother cell to the bud.

272 ling is mediated by a channel that links the mother cell to the forespore.

273 Delivery of cER from mother cells to buds, which is termed cER inheritance, o

274 Ssd1 speeds Q-cell wall assembly and enables mother cells to enter this state.

275 onuclease is expressed in late G1 in haploid mother cells to initiate mating-type interconversion.

276 s, as inhibited mating-type switching causes mother cells to shun their own daughters.

277 s NA might be exported by glucose-restricted mother cells to survive later generations, we developed

278 at progeny can send feedback signals to the 'mother' cell to modify its cell cycle status.

279 The proteolytic activation of the mother cell transcription factor pro-sigma(K) is control

280 ry at cell-cycle checkpoints before mitosis, mother cells transmit DNA damage-induced p53 protein and

281 eriohopanetetrol, to remain localized to the mother cell type.

282 (SpoIIIAA through SpoIIIAH) produced in the mother cell under the control of sigma(E) are ordinarily

283 Yeast mother cells undergo a limited number of asymmetric divi

284 row from the bud neck toward the back of the mother cell until their length roughly equals the diamet

285 plasma membrane and remained robustly in the mother cell upon cell division.

286 We find that Pma1 activity antagonizes mother cell vacuole acidity by reducing cytosolic proton

287 at the molecular level and connects with the mother cell wall remains unclear.

288 monas achieves the timely degradation of its mother cell wall, a type of ECM, through the budding of

289 post-mitotic hatching of daughters from the mother cell wall.

290 Spore tetrads develop in spore mother cell walls within a mucilaginous matrix, both of

291 C. albicans budding mother cells were found to be nonadherent, which contras

292 sting of two chambers, the forespore and the mother cell, which are linked by pathways of intercellul

293 s selected to differentiate into a megaspore mother cell, which is committed to giving rise to the fe

294 enlarges and differentiates into a megaspore mother cell, which then undergoes meiosis to give rise t

295 , led to the formation of multiple megaspore mother cells, which were able to initiate gametogenesis.

296 originate from a stalk-like extension of the mother cell whose terminal segment is gradually remodele

297 Detachment initiates in the mother cell with the phosphorylation of Vac17 that recru

298 wth could occur after asymmetric division in mother cells with no active sigma(E).

299 bearing twins are substantially longer than mother cells with single spores.

300 In growing mother cells, with no active sigma(E), Spo0A-directed tr