ライフサイエンスコーパス: motility

1 in is necessary for TGF-beta1-dependent cell motility.

2 t of phase in order to stimulate directional motility.

3 hat mediates opposing effects on growth cone motility.

4 utants have increased adhesion and decreased motility.

5 ge of cells and play important roles in cell motility.

6 opentanonated EF-P is inhibitory to swarming motility.

7 model that reproduced the range of observed motility.

8 tin complexes that have defective long-range motility.

9 ure for cellular repair and increasing sperm motility.

10 aling, cell cycle progression, polarity, and motility.

11 ing control of Tau's inhibition of kinesin-1 motility.

12 n and cytoskeletal pathways that govern cell motility.

13 the urinary bladder and defective intestinal motility.

14 of network growth to impose steering during motility.

15 duced cell proliferation, and increased cell motility.

16 oxygen thus affecting cell responses such as motility.

17 nor EGF stimulation have any effect on cell motility.

18 s epithelial maintenance or gastrointestinal motility.

19 cal responses that require rapid directional motility.

20 bosomal protein production before inhibiting motility.

21 fferent metabolic states underpin altered DC motility.

22 the S100A4 level and reduced TMD's cellular motility.

23 es Rac1 transcription to increase tumor cell motility.

24 D cells, TMD cells exhibited higher cellular motility.

25 trergic myenteric neuron quantifications and motility.

26 epithelial cells, regulates epithelial cell motility.

27 ynein enables She1 to directly affect dynein motility.

28 y She1 is required for its effects on dynein motility.

29 th canonical mechanisms of plus-end-directed motility.

30 ng alterations in intestinal sensitivity and motility.

31 to synergize with TGF-beta1 to promote cell motility.

32 like protein that regulates the direction of motility.

33 of MglA and thus stabilizes the direction of motility.

34 SM-3/KIF17 without affecting kinesin-3 KLP-6 motility.

35 oving direction and show severe defects in S-motility.

36 egulated due to its role in pathogenesis and motility.

37 ion alone does not directly affect kinesin-1 motility.

38 ncluding epithelial barrier permeability and motility.

39 rotubules where it strongly inhibits kinesin motility.

40 signaling pathway, thus increased tumor cell motility.

41 ATPase activity and in vitro actin filament motility.

42 es in epithelial cell-cell adhesion and cell motility.

43 a unique form of locomotion known as gliding motility.

44 podia are common features of eukaryotic cell motility.

45 to DDB does not strongly disrupt processive motility.

46 operly localizing adhesion sites during cell motility.

47 at kinetochores where they drive chromosome motility.

48 ntral driving force underlying lamellipodial motility.

49 thelial monolayers to exhibit an increase in motility, a feature reminiscent of cancer metastasis.

50 For motility, a leading-lagging cell polarity is established

51 These implants resulted in excellent motility after enucleation surgery, although many studie

52 Eighteen of the studies did not assess motility after enucleation surgery, and the 7 that did e

53 Gliding motility allows malaria parasites to migrate and invade

54 ntestine diameters, but increased intestinal motilities along with thickened muscle fibers, demonstra

55 Single molecule motility analysis revealed that the step sizes of both M

56 d LKB1 expression, inhibited individual cell-motility and abrogated the stem-like phenotype of breast

57 to alleviate pain and inflammation, regulate motility and appetite, and produce anticancer, anxiolyti

58 nto Ca(2+)/calpain regulation of growth cone motility and axon guidance during neuronal development.

59 efect, alterations in the lipid A structure, motility and biofilm formation defects, as well as chang

60 here suggest that c-di-GMP can regulate both motility and biofilm formation through a single effector

61 bservations that energy-consuming processes (motility and bioluminescence) are downregulated, and mic

62 ts concentration-dependent effects on dynein motility and can synergize with dynactin to enhance proc

63 e with obvious colonization-related roles in motility and carbon metabolism, as well as 44 other gene

64 lated flagellar assembly process can abolish motility and cause negative physiological outcomes.

65 organization is important for regulation of motility and cell division and changes over time.

66 concerning the spatiotemporal regulation of motility and cell division in M. xanthus and illustrates

67 epithelial end buds, where it enhances cell motility and cell-cell adhesion dynamics.

68 GBPs inhibit actin-dependent motility and cell-to-cell spread of bacteria but are ant

69 m GBP encapsulation to resume actin-mediated motility and cell-to-cell spread.

70 0A4(-/-) mice exhibit defects in directional motility and chemotaxis in vitro and reduced recruitment

71 lts suggest that the developmental states of motility and competence are related and most commonly oc

72 wound-healing in vitro assay, impaired cell motility and cytokinesis.

73 of ILK signaling, which is involved in cell motility and cytoskeletal reorganization, resulted in re

74 ronger E-cadherin localization, reduced cell motility and decreased dynamics of transient cell separa

75 cells corresponding to increased tumor cell motility and dissemination.

76 rointestinal (GI) (patho)physiology; from GI motility and epithelial barrier function to enteric neur

77 t controls many diverse functions, including motility and epithelial permeability.

78 can make a major contribution to kinetochore motility and establish a direct approach for measuring t

79 d cell proliferation, colony formation, cell motility and expression of beta-catenin, Snail, Slug, Ze

80 d not impact cell viability but reduced cell motility and extracellular matrix invasion, as well as e

81 tSper) is essential for sperm hyperactivated motility and fertility.

82 rs (SFs) play key roles in driving polarized motility and generating traction forces, yet little is k

83 s) to generate a pmf that sustains efficient motility and growth for colonization and pathogenesis.

84 We show the necessity of the pmf for motility and growth of C. jejuni.

85 PCP pathway contributes significantly to the motility and hence the invasiveness of GBM cells, and th

86 ion of actin filaments and their function in motility and host cell invasion of apicomplexan parasite

87 tric DB administration decreases both antral motility and hunger ratings during the fasting state, po

88 ssess its effect on fasting gastrointestinal motility and hunger ratings, motilin and ghrelin plasma

89 glideosome, which is essential for parasite motility and includes the MyoA light chain myosin tail d

90 This also induced PC3 cancer cell motility and increased colony size in 2D cultures.

91 ry identified PTPN23 as a suppressor of cell motility and invasion in mammary epithelial and breast c

92 propriation of primordial mechanisms of cell motility and invasion, and the influence of multiple asp

93 hown to be involved in modulating tumor cell motility and invasion, cancer stem cell viability and di

94 was sufficient to recapitulate the increased motility and invasive phenotypes characteristic of trans

95 ficient early HCMV-induced enhanced monocyte motility and later for HCMV-induced monocyte-to-macropha

96 show that incubation temperature influences motility and limb bone growth in West African Dwarf croc

97 Cell motility and migration requires the reorganization of th

98 over-acetylated tubulin led to inhibition of motility and mitosis.

99 We show that motility and patch-clamp responses to levamisole and pyr

100 The motility and signaling functions of the primary cilium r

101 Shigella mediates intracellular motility and spreading via actin comet tail formation.

102 chemotaxis-like Hmp system is essential for motility and the coordinated polar accumulation of PilA

103 idium difficile, c-di-GMP inhibits flagellar motility and toxin production and promotes pilus-depende

104 ly slow NMIIB dynamics, thus increasing cell motility and traction and enabling chemotaxis.

105 ed monocytes, resulting in enhanced monocyte motility and transendothelial migration, prolonged monoc

106 hat is typically dedicated to the control of motility and which is usually essential for virulence.

107 Surprisingly, S-motility and wild-type reversal frequency are restored i

108 ns, and mechanical responses to shear, motor motilities, and network rearrangements.

109 -based adhesion assays, live-cell imaging of motility, and actin polymerization studies to confirm a

110 analysis identified selection for changes in motility, and antimicrobial susceptibility testing sugge

111 significantly increased C. jejuni's growth, motility, and biofilm formation under microaerobic (5% O

112 e effects of the DYNC1H1 mutations on dynein motility, and consequently their links to neuropathology

113 lly, a behavior essential for cell division, motility, and differentiation.

114 perm count, sperm concentration, morphology, motility, and ejaculate volume were assessed.

115 structural integrity of the conoid, parasite motility, and host cell invasion.

116 understood how these factors influence motor motility, and in vitro assays and live cell observations

117 tical for epithelial-mesenchymal transition, motility, and invasion by cancer cells.

118 ivity determines polarized NC morphology and motility, and is regulated by the asymmetrically localiz

119 nteric neurons to influence gastrointestinal motility, and metabolites that stimulate the "gut-brain

120 vity diminished MPNST cell proliferation and motility, and that these effects were not accompanied by

121 trongly interfered with bleb formation, cell motility, and the ability of the cells to reach their ta

122 ons-such as cell proliferation, survival, or motility-and is involved in metabolic homeostasis, infla

123 a laser trap to measure the function of the motility apparatus of living Toxoplasma gondii by adheri

124 n assays in suckling mice that inhibition of motility appears to be responsible for most, if not all,

125 tic directional forces generated during cell motility are essential for adaptive T-cell immunity agai

126 ed with 89 (32%) of 277 patients with normal motility as defined with CC-S (p<0.0001).

127 -infection strain resulted in a reduction of motility as measured in swimming and swarming assays.

128 dict the maximal velocity of contraction (by motility assay or sarcomeric shortening) at different ac

129 terize the trajectories of actin in a myosin motility assay, and develop order parameters to measure

130 es an increase in duty ratio examined in the motility assay.

131 velocity more than 100-fold in the in vitro motility assay.

132 Sup1 does not translocate actin filaments in motility assays in vitro.

133 stimation of motility parameters in stepping-motility assays.

134 lection of movement, determined via in vitro motility assays.

135 tochondrial switch of the cell proliferation-motility balance in cancer, and its pathway may represen

136 aviour, and facilitates predictive-design of motility-based pattern formation.

137 ively represent a genetic signature of alpha-motility because both are used for pseudopod formation.

138 ted coordination of mitochondrial stress and motility before activation of Parkin-mediated mitophagy.

139 r life cycles and drives directional gliding motility between cells, as well as invasion of and egres

140 progressive changes in liquid media growth, motility, biofilm formation, and acute insect virulence,

141 evated indole levels significantly decreased motility, biofilm formation, exopolysaccharide productio

142 -38+unc-29 (L- and/or P-receptors) inhibited motility but knockdown of acr-16+acr-26 (M- and/or N-rec

143 cts with integrins during cell spreading and motility, but little is known about the role of EGFR in

144 balance between cell proliferation and cell motility, but the regulators of this process are largely

145 matrix metalloproteinase-2 activity and cell motility by ROS-activated c-Jun N-terminal kinase pathwa

146 of numerous cellular processes, such as cell motility, cell division and endocytosis.

147 We also measured the motility characteristics of actin filaments on the model

148 lingshot motions characteristic of twitching motility comprise the transition region between differen

149 We find that cytoplasmic motility constitutes a combination of directed motion an

150 , whereas increased tissue rigidity and cell motility/contractility help mediate tumour progression.

151 Our study of dimeric NDK5 in a flagellar motility control complex, the radial spoke (RS), has rev

152 ked effect on tumor structure, high cellular motility could lead to faster cell mixing and lower obse

153 The model analysis shows that initiation of motility critically depends on three dimensionless param

154 that involve actin- and microtubule-mediated motility, cytoskeleton-membrane scaffolds and signaling

155 s and trypanosome morphologies to high-speed motility data, which paves the way for cross-disciplinar

156 iptomics correctly predicted a 2AA-dependent motility defect and identified additional areas of metab

157 lagellar assembly components, which led to a motility defect.

158 Cell motility depends on tight coordination between the micro

159 chromatin organization, signaling, adhesion, motility, development and metabolism.

160 265 (83%) of 321 patients with major motility disorders and 107 (70%) of 152 patients with mi

161 diet (60% kcal from fat) is associated with motility disorders inducing constipation and loss of nit

162 The diagnostic sensitivity of HRM for major motility disorders is increased with use of the STM comp

163 ENS and how this system can be used to study motility disorders of the human gastrointestinal tract.

164 ers and 107 (70%) of 152 patients with minor motility disorders reported symptoms during the STM (p=0

165 Diagnosis of oesophageal motility disorders was based on the Chicago Classificati

166 studies increases test sensitivity for major motility disorders.

167 neuropathy causes a wide range of severe gut motility disorders.

168 ns to regulate dynamics of cell adhesion and motility during epithelial branching morphogenesis.

169 as a multi-step mechanism to coordinate cell motility during migration.

170 At present, it is not clear how twitching motility emerges from these initial minimal conditions.

171 The directional control of motility, especially combined with the potential to inco

172 Cells employing amoeboid motility exhibit repetitive cycles of rapid expansion an

173 Autocrine motility factor (AMF) is a tumor-secreted cytokine that

174 The growth and motility factor Hepatocyte Growth Factor/Scatter Factor

175 hich together with other EVI1-dependent cell motility factors such as RHOJ regulated breast carcinoma

176 ly tuned to compromise between generation of motility forces and restriction of intercellular communi

177 m concentration, increased progressive sperm motility generated more pyruvate conversion to lactate a

178 ted with cell cycle, chromatin, cytoskeleton/motility, immunity, and apoptosis.

179 However, they regulate intestinal motility in a sex-dependent manner.

180 However, a profoundly enhanced motility in aligned collagen matrices is observed for th

181 ased reporter assays, inhibit Gas6-inducible motility in Axl-expressing cell lines, and suppress H129

182 rial flagellum is the principal organelle of motility in bacteria.

183 , we show that Pontin is essential for cilia motility in both zebrafish and mouse and that Pontin and

184 together with SCAR correctly predicts alpha-motility in disease-causing chytrid fungi, which we show

185 ut are required for regulation of intestinal motility in females.

186 GAS8) have been linked to defects in ciliary motility in humans and lead to a ciliopathy known as pri

187 histology, daily sperm production and sperm motility in knock-out and wild-type mice.

188 biofilms, is required for this T4P-mediated motility in M. xanthus as the putative trigger of T4P re

189 Directed migration is essential for cell motility in many processes, including development and ca

190 ogen-driven contributor to cell survival and motility in prostate cancer.

191 allows these small organisms to adjust their motility in response to background flow.

192 r prominent rises in [Ca(2+) ]i nor enhanced motility in response to TRPC4 activation unless they ove

193 to contractility of striated muscle and cell motility in several contexts.

194 haellum components during starvation-induced motility in Sulfolobus acidocaldarius.

195 a key regulator for adhesion during gliding motility in the rodent malaria model P. berghei.

196 They broadly rescue morphology and motility in the zebrafish mutant, but alter motor axon m

197 uter hair cells in the cochlea have a unique motility in their cell body based on mechanoelectric cou

198 helial barrier function and gastrointestinal motility in these mice and littermate controls, and anal

199 e show that spontaneous pauses during T cell motility in vitro and in vivo coincide with episodes of

200 d the role of CCL7 in mast cell activity and motility in vitro and investigated the requirement for C

201 secreted cytokine that stimulates tumor cell motility in vitro and metastasis in vivo.

202 tations with the strongest effects on dynein motility in vitro are associated with MCD.

203 the most commonly observed modes of plasmid motility in vivo, we suggest that the operation of the P

204 nt increases in [Ca(2+) ]i and promotes cell motility in wound healing and transwell migration assays

205 s leads to an unprecedented range of complex motilities, including oscillatory swimming, helical swim

206 of embryonic chickens revealed that altered motility, independent of temperature, may underpin this

207 hibitor, thereby inhibiting endothelial cell motility, independently of pore function.

208 We identify a motility-induced swim stress that adds to the interactio

209 ureolysis on the other hand, and biofilm and motility inhibitors did not affect ureolysis.

210 Remarkably, dynactin can bias motility initiation locally from microtubule plus ends b

211 odeling method indicated that decreased cell motility inside the aggregates, a biased walk toward agg

212 ating many cellular functions including cell motility, intercellular and intracellular signaling, gen

213 n of the growth, cytoskeleton remodeling and motility, invasion of PDAC cells-all collectively contri

214 f T. gondii including secretion of adhesins, motility, invasion, and egress.

215 ctions in integrin signaling to promote cell motility, invasion, proliferation, and survival.

216 Poor sperm motility is a common cause of male infertility for which

217 Collectively, our results demonstrate that motility is intimately coupled to the growth-rate of the

218 tly associated with cilia defects, and cilia motility is lost in a number of ciliated tissues along w

219 Sperm motility is powered by adenosine triphosphate but the re

220 We propose that vimentin's role in cell motility is to govern the alignment of traction stresses

221 Evidently, between these species, CESA motility is well conserved.

222 nt of follower cells but not for leader cell motility itself, which instead utilizes focal adhesion k

223 formerly DgrA) of Bacillus subtilis inhibits motility like a molecular clutch that disengages MotA.

224 ions showed that MCPIP1 regulated ccRCC cell motility, lung metastasis, and mesenchymal phenotype by

225 Motility measurements showed that resident macrophages w

226 development of models for the bidirectional motility mechanism of fission yeast kinesin-5 and provid

227 ovement, indicating similarities between the motility mechanisms for both directions.

228 We study two distinct motility mechanisms of Myxococcus xanthus, namely, twitc

229 e of mammalian mediator of ErbB2-driven cell motility, MEMO-1, as a protein that inhibits BLI-3/NADPH

230 actin-filled pseudopods that we call "alpha-motility." Mining genomic data reveals a clear trend: on

231 t it to be a common and widespread escape or motility mode in complex and structured environments.

232 Some of the features of these motility modes resemble those of some single-celled prot

233 These regulators of adhesion and motility mutants have increased adhesion and decreased m

234 rface proteins did not change cell migration motility nor directionality in EFs.

235 e examined the contribution of dynein to the motility of an endogenous dendritic cargo and found that

236 ignment of collagen does not alter the total motility of breast cancer cells, but simply redirects th

237 late the proliferation, differentiation, and motility of cells.

238 tive study of the long timescale phototactic motility of Chlamydomonas at both single cell and popula

239 inverse relationship on the distribution and motility of lysosomes in dendrites.

240 NFAT-AP1 promoter activity and decreased the motility of murine CD4(+) primary T cells on ICAM-1-coat

241 t it contributes causatively to the invasive motility of prostate cancer cells.

242 elopment, in the proliferation, survival and motility of RAC1(P29S)-mutant human melanoma cells, and

243 essential role in the flagellar assembly and motility of T. denticola.

244 ential to complete cytokinesis by activating motility of the male flagellum.

245 deling has suggested that the morphology and motility of these spirochetes depends crucially on the f

246 duced MT stabilization and the intracellular motility of virus particles.

247 no correlation between biofilm formation and motility on one hand, and ureolysis on the other hand, a

248 KlpA exhibits plus end-directed processive motility on single microtubules, but reverts to canonica

249 oxin biosynthesis without affecting swimming motility or global intracellular c-di-GMP.

250 Many motility organelles are complex surface appendages that

251 denticola periplasmic flagella (PF), unique motility organelles of spirochetes, in stimulating an in

252 Organisms have evolved motility organelles that allow them to move to favourabl

253 serving as a tutorial for the estimation of motility parameters in stepping-motility assays.

254 in these sensory neurons to influence sperm motility parameters.

255 Our results show that changes in the motility pattern of microorganisms can be induced by sim

256 Macrophage motility, phagocytosis, and differentiation in vivo are

257 haracterize the biochemical, structural, and motility phenotypes of two mutations in the DRC2 gene of

258 F1 in the dysregulation of cell invasion and motility phenotypes seen in transformed cells and also h

259 gle-cell PCR, whole muscle cell patch clamp, motility phenotyping (Worminator), and dsRNA for RNAi fo

260 gulate diverse cellular events, such as cell motility, polarity, and vesicle traffic.

261 By characterizing the motility properties of kinesin-2 motors as a function of

262 RpoN* expression significantly reduced motility, protease secretion, pyocyanin and pyoverdine p

263 erfacing protein modules that sort polarized motility proteins to the correct cell poles or cause the

264 ormation, the morphological feature of alpha-motility, providing evidence for a widely distributed mo

265 We show that flagella motility, Rab11, and actin coordination are necessary fo

266 rate how differences in group and individual motility rates can influence the persistence of a popula

267 analyses showed that regulation of the cell motility receptor RHAMM by the RB/E2F pathway was critic

268 hondrial distribution, altered mitochondrial motility, reduced mitochondrial membrane potential, and

269 Mena(INV), an isoform of the motility regulator protein Mena, contributes to prometas

270 However, how calpain regulates growth cone motility remains unclear.

271 of regulating Tau's inhibition of kinesin-1 motility remains unknown.

272 s couple or uncouple their proliferative and motility responses to ECM stiffness.

273 nd treatment of injury-associated intestinal motility/sensory disorders.

274 Moreover, RSK2-mediated motility signaling depends on RhoA and -B, but not RhoC.

275 Interpretation of cell motility studies though is often restricted by the appli

276 ptional pathway for bleb-associated invasive motility, such as during entosis.

277 The ionic strength dependence of in vitro motility suggests the inhibition may be at least partial

278 rved transcriptional response and subsequent motility switch in cancer cells resulting in the formati

279 ility to polarize their Golgi and coordinate motility systems for efficient movement.

280 genes for biofilm formation or for swarming motility-the output phenotypes.

281 Microglia exhibit two modes of motility: they constantly extend and retract their proce

282 e cancer cells in vitro, inducing tumor cell motility through a nonproteolytic signal transduction ca

283 rusions and accelerates dendritic filopodial motility through an Abl kinase-dependent pathway.

284 can yield additional information on gastric motility to help explain patients' symptoms.

285 onic cells to couple their autonomous random motility to non-autonomous signals arising from the expa

286 mediator of microtubule-based mitochondrial motility, to study how changes in mitochondrial position

287 TIC phenotypes, including tumorspheres, cell motility, tumorigenesis, as well as in vitro and in vivo

288 of 633 nm coherent, red laser light on sperm motility using a novel wavelet-based algorithm that allo

289 Manipulation of cellular motility using a target signal can facilitate the develo

290 ation of the SNpc increased gastric tone and motility via activation of dopamine 1 receptors in the d

291 tionship between energy metabolism and sperm motility we used dissolution Dynamic Nuclear Polarizatio

292 To study filopodial motility, we collected and analyzed image data on filopo

293 links cell mechanics to cell shape and cell motility, we formulate a generalized mechanical inferenc

294 these nonspecific physical signals influence motility, we look at the response of individual bacteria

295 nitoring of cytosolic Ca(2+) along with cell motility, we show that spontaneous pauses during T cell

296 movements of cells undergoing lamellipodial motility, we systematically explore minimal free-boundar

297 Gastric tone and motility were recorded after N-methyl-d-aspartate microi

298 quantitative score incorporating feeding and motility, were significantly more likely to survive duri

299 but reverts to canonical minus end-directed motility when anchored on the surface in microtubule-gli

300 ENSC into the colon rescues impaired colonic motility with formation of extensive networks of transpl