ライフサイエンスコーパス: motogenic

1 in and HSPGs but retained full mitogenic and motogenic activities on target cells in culture.

2 enic responses may not be tightly coupled to motogenic activity and further illustrates the multifunc

3 rotease-guided cellular responses, including motogenic activity and transepithelial resistance of epi

4 ain explants demonstrate regionally specific motogenic activity due to HGF/SF.

5 This motogenic activity gave rise to structures resembling fi

6 pha) as the factor fully responsible for the motogenic activity in keratinocyte secretion.

7 atin and laminin was utilized to inhibit the motogenic activity of endostatin.

8 tidic acid (LPA) and accounts for 80% of the motogenic activity of the conditioned medium.

9 This motogenic activity required ES domain oligomerization, w

10 domains (4-5)FnI and (3)FnIII, and restores motogenic activity to the FN N-terminal fragment.

11 ignaling confers mitogenic, morphogenic, and motogenic activity to various cells.

12 The data suggest that HGF/SF motogenic activity, which is essential for normal develo

13 n exhibits a potent and substratum-dependent motogenic activity, with half-maximal response manifest

14 erization but lacks significant mitogenic or motogenic activity.

15 n keratinocytes, beta2-AR activation is anti-motogenic and anti-mitogenic with both mechanisms being

16 atocyte growth factor (SF/HGF) can stimulate motogenic and morphogenetic activities in cultured epith

17 nal cytokine capable of eliciting mitogenic, motogenic and morphogenetic activities in responsive cel

18 rb2 interaction contributes primarily to the motogenic and morphogenic responses to HGF, and that the

19 ys cytokine properties, eliciting mitogenic, motogenic, and differentiation activities, and has been

20 motility factor (AMF)] eliciting mitogenic, motogenic, and differentiation functions through binding

21 e motility factor (AMF)-eliciting mitogenic, motogenic, and differentiation functions, and PGI has be

22 ne tyrosine kinases that activate mitogenic, motogenic, and differentiative responses in different ti

23 al paracrine regulator possessing mitogenic, motogenic, and morphogenetic activities in cultured epit

24 e-derived pleiotropic factor with mitogenic, motogenic, and morphogenic activities on a number of dif

25 eptors that when activated induce mitogenic, motogenic, and morphogenic cellular responses.

26 ovel mechanism for regulating the mitogenic, motogenic, and morphogenic effects of hepatocyte growth

27 actor (HGF) is a polypeptide with mitogenic, motogenic, and morphogenic effects on different cell typ

28 scatter factor (HGF/SF) possesses mitogenic, motogenic, and morphogenic properties and has recently b

29 te growth factor (HGF) stimulates mitogenic, motogenic, and morphogenic responses in various cell typ

30 c tyrosyl residues in Met induces mitogenic, motogenic, and morphogenic responses.

31 ideo microscopy we find that BDNF is acutely motogenic as it stimulates migration of individual granu

32 by HGF/NK2, an alternative HGF isoform with motogenic but not mitogenic or morphogenic activities.

33 d human keratinoytes, which contained strong motogenic, but not mitogenic, activity.

34 Consistent with restitution, motogenic concentrations of HBD2 and CCL20 did not induc

35 e motility factor (AMF) eliciting mitogenic, motogenic, differentiation functions and has been implic

36 esion and migration and even potentiated the motogenic effect of brevican.

37 We found that the motogenic effect of NO, Gab1, and SHP2 was blocked by th

38 ele, decreased cell motility and blocked the motogenic effect of NO, whereas the expression of T19N-R

39 dominant-negative SHP-2 allele, blocked the motogenic effect of NO.

40 ing MLC or ERK phosphorylation inhibited the motogenic effect of strain on fibronectin.

41 lls may explain the matrix dependence of the motogenic effect.

42 ind that E-peptide signaling, mitogenic, and motogenic effects are dependent upon IGF-IR.

43 t EB has been reported to have mitogenic and motogenic effects independent of IGF-I.

44 P) and an LRP antagonist (RAP) blocked these motogenic effects of PAI-1, while a PAI-1 mutant that di

45 ion, whereas angiopoietin-1 (Ang-1) had only motogenic effects.

46 ocytes (37 +/- 6% of the level of the highly motogenic EGF) as determined in a two-dimensional in vit

47 Paracrine motogenic factors, including motility cytokines and extr

48 n with stimulation of production of secreted motogenic factors.

49 these data demonstrate that BDNF is directly motogenic for granule cells and provides a directional c

50 g the dissection of direct from indirect and motogenic from mitogenic effects of genes and molecules

51 icroM) treatment of NR6 cells expressing the motogenic full-length (WT) and truncated c'1000 EGFR dec

52 e uncoupled survival from chemoattractive or motogenic functions of this ligand using mice that carry

53 skeleton in response to stimulation with the motogenic growth factor platelet-derived growth factor.

54 h mitogenic in mast cells, this mutation was motogenic in melanocytes.

55 ested the hypothesis that insulin alters the motogenic phenotype of cultured rat aortic smooth muscle

56 that Sema3E/PlexinD1 signalling controls the motogenic potential of CR cells in vitro and in vivo.

57 by enhancing the mitogenic, morphogenic, and motogenic properties of Met.

58 gration-stimulating factor (MSF) is a 70-kDa motogenic protein previously reported to be expressed by

59 to be necessary and sufficient to induce the motogenic response observed in response to CagA+ strains

60 gth HGF, but stimulates cell scatter, or the motogenic response to HGF.

61 motactic checkerboard analysis, the greatest motogenic response to HGF/SF was achieved by invasive, i

62 diate filaments) and the regulation of their motogenic response to HGF/SF, a key step in local invasi

63 VEGF(165)) did not induce a proliferative or motogenic response.

64 wever, the molecular mechanisms that mediate motogenic responses to this growth factor are not clearl

65 stinct effectors, various cell type-specific motogenic responses.

66 d functional distinction from the archetypal motogenic scatter factors hepatocyte growth factor and m

67 NC EGF-like (EGFL) repeats as these activate motogenic signaling cascades.

68 To understand its motogenic signaling events, we have studied the role of

69 in-containing protein to positively regulate motogenic signaling pathways.

70 learn more about the STAT-3-cPLA(2) axis in motogenic signaling, here we have studied its role in VS

71 Accordingly, PM-based motogenic signals (PI3-kinase-Akt and PLCgamma1) are amp

72 on tyrosines and can transmit mitogenic and motogenic signals following VEGF binding, while Flt-1 is

73 emodel the actin cytoskeleton in response to motogenic stimuli are complex and a topic of intense stu

74 ired for invadosome formation in response to motogenic stimuli.

75 their responsiveness to ambient GABA from a motogenic to a stop signal.

76 ass associated with the membrane fraction in motogenic WT and c'1000 EGFR NR6 cells but not in cells

77 cell motility in NR6 cells expressing either motogenic (WT and c'1000) or nonmotogenic (c'973) EGFR;