ライフサイエンスコーパス: motor coordination

1 rotoxicity (as tested by a rota-rod test for motor coordination).

2 mpaired muscle grip strength, and defects in motor coordination.

3 rtical regions involved in language and fine motor coordination.

4 anges in ANS function, locomotor activity or motor coordination.

5 in cerebellar conditioned learning and fine motor coordination.

6 mpact the normal development of language and motor coordination.

7 xploration of novel objects, locomotion, and motor coordination.

8 many nervous system functions, particularly motor coordination.

9 RPC5 knockout mice have deficits in gait and motor coordination.

10 play more severe impairments than females in motor coordination.

11 attern of sensory input specificity and thus motor coordination.

12 brain development, spontaneous movement, and motor coordination.

13 automatic reflexes to spatial perception and motor coordination.

14 nd better performance on one measure of fine motor coordination.

15 standing and walking, cognitive ability, and motor coordination.

16 to be central to the role of this system in motor coordination.

17 ontrols in the accelerating rotarod test for motor coordination.

18 of the B2-ablated mice demonstrated impaired motor coordination.

19 cognitive abilities, executive functions and motor coordination.

20 d reduced hyperpathic responses and improved motor coordination.

21 ia was observed at doses that did not affect motor coordination.

22 ined, indicating the potential complexity of motor coordination.

23 to the rescue of host PNs and restoration of motor coordination.

24 ze of the dopaminergic neurons as well as in motor coordination.

25 of CDA54 did not affect acute nociception or motor coordination.

26 f cognition, level of locomotor activity, or motor coordination.

27 ts of Delta(9)-tetrahydrocannabinol (THC) on motor coordination.

28 ding-related cognitive deficits and impaired motor coordination.

29 pecific motor deficits, namely, sedation and motor coordination.

30 e in the rotarod, pole, and cagetop tests of motor coordination.

31 eneration, myelination defects, and impaired motor coordination.

32 ctional imaging that the cerebellum supports motor coordination.

33 morphology and are impaired in cognition and motor coordination.

34 prior to ICB vehicle had no effect on normal motor coordination.

35 -expressed Punc in the cerebellar control of motor coordination.

36 revealed when increased demands were made on motor coordination.

37 d are crucial to the circuitry that controls motor coordination.

38 al-dependent learning and memory, as well as motor coordination.

39 d hyperpathic responses, along with improved motor coordination.

40 gait, muscle strength, and other features of motor coordination.

41 ng the role of the olivocerebellar system in motor coordination.

42 bromocriptine prevented 3-AP-induced loss of motor coordination.

43 ced both antinociception and disturbances of motor coordination.

44 zation consists of a specific, circumscribed motor coordination.

45 process causes progressive deterioration of motor coordination.

46 ncluding cognitive decline and impairment of motor coordination.

47 ns, where regularity is believed crucial for motor coordination.

48 toxicity in a variety of behaviors including motor coordination.

49 neurons, exhibit impairments in balance and motor coordination.

50 used to investigate the neural circuitry of motor coordination.

51 mediators and neurotrophic factor levels and motor coordination.

52 ranslation of timing information to auditory-motor coordination.

53 automatic reflexes to spatial perception and motor coordination.

54 Tight glucose control improved motor coordination (9% [95% CI, 0%-18%] to 20% [95% CI,

55 vealed that the Syt IV mutants have impaired motor coordination, a result consistent with constitutiv

56 ing those for general health and metabolism, motor coordination, activity, and sleep behavior.

57 ocampus-dependent spatial learning, impaired motor coordination, altered response to novelty, and sen

58 llows researchers to quantify differences in motor coordination among genotypes of mice that may diff

59 of alcohol cause considerable impairment of motor coordination, an effect that substantially involve

60 A mice displayed a significant impairment of motor coordination and a motor learning delay.

61 IDkk1 mice show impaired motor coordination and are irresponsive to amphetamine.

62 o needed for mGluR1-dependent slow EPSCs and motor coordination and associates with mGluR1, GluRdelta

63 hyperglycemia, associated with improved fine motor coordination and attention.

64 nd other neurological problems, such as poor motor coordination and attentional deficits.

65 nt pattern analysis, and progressive loss of motor coordination and balance at the age of 12 months d

66 Motor coordination and balance were more adversely affec

67 nal cord areas, motor-evoked potentials, and motor coordination and balance, we determined that axona

68 output of these cells and the regulation of motor coordination and balance.

69 FGF14 in adult Purkinje neurons also impairs motor coordination and balance.

70 Finally, motor coordination and both spontaneous and psychostimul

71 ng it with the commonly used rotarod test of motor coordination and by using eye movements to monitor

72 splicing of genes that likely contribute to motor coordination and cell survival.

73 Cerebellar motor coordination and cerebellar Purkinje cell synaptic

74 The cerebellum is critical for motor coordination and cognitive function and is the tar

75 (KO) mice display no deficits in measures of motor coordination and cognitive function but exhibit in

76 SCA1 patients lose motor coordination and develop slurred speech, spasticit

77 alcoholic beverages produces alterations in motor coordination and equilibrium that are responsible

78 Inferior olive (IO) neurons are critical for motor coordination and exhibit oscillations in membrane

79 CD4(-/-) mice showed partial restoration of motor coordination and gait that coincided temporally wi

80 gative symptoms group still exhibited poorer motor coordination and higher levels of NSS, as well as

81 ause null mutations exhibit deficits in fine motor coordination and hippocampus-dependent memory.

82 NgR123-null mice displayed reduced motor coordination and hyperactivity.

83 n a progressive movement disorder, including motor coordination and imbalance, which is typical for a

84 es in vivo, resulting in hyperactivity, poor motor coordination and impaired cue-based learning in mi

85 The inferior olive plays a critical role in motor coordination and learning by integrating diverse a

86 The inferior olive plays a critical role in motor coordination and learning by integrating diverse a

87 e cerebellar cortex is centrally involved in motor coordination and learning, and its sole output is

88 tical element of the circuitry that controls motor coordination and learning.

89 otor sensitization to cocaine and attenuated motor coordination and learning.

90 Cplx1-/- mice show pronounced deficits in motor coordination and locomotion including abnormal gai

91 Sustained improvements in motor coordination and locomotor activity were observed,

92 cerebellar cortex and play a crucial role in motor coordination and maintenance of balance.

93 used strain-dependent changes in the weight, motor coordination and motor learning capability of mice

94 aphical location can change the body weight, motor coordination and motor learning capability of wild

95 Motor coordination and motor learning require an intact

96 proper connectivity of zones is critical for motor coordination and motor learning, and in several ne

97 es, they exhibited age-dependent deficits in motor coordination and motor learning.

98 of DOR using naltrindole partially improved motor coordination and normalized spatial navigation and

99 th better performance on one measure of fine motor coordination and on one measure of attention and e

100 ssociated, at the age of 4 years, with worse motor coordination and planning but not with lower IQ or

101 s of CR on outcomes such as immune function, motor coordination and resistance to sarcopenia in rhesu

102 We found that while motor coordination and reward learning were largely unch

103 urse of GD mice, with increased survival and motor coordination and salutary effects on cerebral as w

104 opaminergic drugs, and by subtle deficits in motor coordination and sensorimotor gating.

105 ditioning, but do exhibit mild impairment of motor coordination and social discrimination.

106 nt mice are viable and have deficits in fine motor coordination and some forms of memory.

107 chlear brainstem nuclei, which contribute to motor coordination and sound processing, respectively.

108 at mice invalidated for LXRs exhibit altered motor coordination and spatial learning, thinner myelin

109 strength, sensory neglect, gait impairment, motor coordination and spatial navigation tests.

110 alities and correlated strongly with reduced motor coordination and spinal cord atrophy.

111 AKAP150 null mice also exhibit deficits in motor coordination and strength that are consistent with

112 acemaking in Purkinje cells is essential for motor coordination and suggest that K(Ca) channels may c

113 eflexive responding, as well as for impaired motor coordination and the higher brain functions of lea

114 e the first to describe a role for RGS9-2 in motor coordination and working memory and implicate RGS9

115 ents could potentially contribute to loss of motor coordination and, thus, pharmacological manipulati

116 al haploinsufficiency altered self-grooming, motor coordination, and apparent motivation in operant c

117 are also hyperactive at night, have reduced motor coordination, and are thigmotactic compared with c

118 l as their wild-type littermates in tests of motor coordination, and both showed aging-related decrea

119 were associated with poorer attention, fine motor coordination, and cognition in the CHAMACOS cohort

120 eficits in spatial learning/memory, impaired motor coordination, and decreased sociability by 4 month

121 logies, such as learning and memory, reward, motor coordination, and Down syndrome.

122 est of Visual-Motor Integration); attention, motor coordination, and executive functions (Amsterdam N

123 eatment also improved pancreatic morphology, motor coordination, and increased life span.

124 communication and social behaviors, impaired motor coordination, and increased stress reactivity and

125 Hypothalamic gene transcription, motor coordination, and life span were also determined.

126 te that the tVTA controls rotation behavior, motor coordination, and motor skill learning.

127 ly, transient improvement in attention, fine motor coordination, and reported well-being were observe

128 that are essential for vision, nociception, motor coordination, and reward processing.

129 tor deficits such as akinesia, bradykinesia, motor coordination, and sensorimotor neglect after unila

130 s include severe mental retardation, loss of motor coordination, and sleep disturbances.

131 macroorchidism, anxiety, mental retardation, motor coordination, and speech articulation deficits.

132 ard motor tests for balance and appendicular motor coordination, and used a novel long-term fluid-lic

133 repeated measures of attention, memory, fine motor coordination, and well-being.

134 were hyperactive, displayed a subtle lack of motor coordination, and were generally more anxious than

135 ith significant improvements in brain edema, motor coordination, and working memory, and abrogated ne

136 re of particular interest for their roles in motor coordination, appetitive, and aversive behavior, a

137 emonstrate that these mice have a deficit in motor coordination as early as 3 months of age, consiste

138 ad increased locomotor activity and impaired motor coordination as juveniles (P35) and young adults (

139 ed to contribute to the observed deficits in motor coordination as well as in learning and cognitive

140 In addition, young AS mice have defects in motor coordination, as well as abnormal brain activity t

141 progressive hind leg weakness and decline in motor coordination at 12 to 16 months of age, followed b

142 began to manifest hyperactivity and abnormal motor coordination at 2 weeks of age but were indistingu

143 ficient for PC-specific Mof display impaired motor coordination, ataxia, a backward-walking phenotype

144 rvive, and surviving mice exhibited impaired motor coordination, audiogenic seizures, and brainstem n

145 Lesioned mice showed normal motor coordination, balance, and general locomotion.

146 cerebellar function is paramount for proper motor coordination, balance, and motor learning.

147 d repetitive behaviors without alteration of motor coordination, balance, or locomotion.

148 t severe difficulties in social interaction, motor coordination, behavioral flexibility, and atypical

149 Interpersonal motor coordination between dyads of patients (n = 45) or

150 re involved in the ataxic null phenotype and motor coordination, but not motor learning.

151 early age and develop a significant loss of motor coordination by 24 weeks of age.

152 eficits: progressive imbalance and decreased motor coordination by 50 weeks, gait deficits by 60 week

153 We propose that these adjustments preserve motor coordination by allowing one subunit to make perio

154 ) rats strongly suggest that alcohol impairs motor coordination by enhancing granule cell tonic inhib

155 We find that alcohol impairs motor coordination by enhancing tonic inhibition mediate

156 egenerative disorder that results in loss of motor coordination caused primarily by a disruption of c

157 bellar cortex is associated with deficits in motor coordination characteristic of ataxia, effects whi

158 generative disease characterized by abnormal motor coordination, cognitive decline and psychiatric di

159 gating, anxiety, hypoactivity, and decreased motor coordination, compared to littermate controls.

160 Furthermore, functional recovery of motor coordination correlated strongly with the percenta

161 on behavioral assays that require extensive motor coordination correlated with tau pathology in corr

162 ion of Htt-Q128 leads to progressive loss of motor coordination, decreased lifespan, and time-depende

163 soluble CX3CL1 isoform reduces impairment of motor coordination, decreases dopaminergic neuron loss,

164 , CKA-deficient flies exhibit PP2A-dependent motor coordination defects.

165 The motor coordination deficit and the loss of neurons are t

166 ehaviour could be rescued, while anxiety and motor coordination deficit could not be recovered in adu

167 ring elementary school, which may indicate a motor coordination deficit, appears to be a risk factor

168 f mutant, a structural change that generates motor coordination deficits and impaired postural phenot

169 recently reported that long term memory and motor coordination deficits are also present in our expe

170 dministered baclofen also showed exaggerated motor coordination deficits compared with their wild-typ

171 It is believed that balance and motor coordination deficits in FXS patients are caused b

172 n through choline supplementation attenuates motor coordination deficits in the mutant offspring.

173 Cs reduces their activity and contributes to motor coordination deficits prior to Abeta aggregation a

174 and visual memory impairment as well as the motor coordination deficits which persisted after succes

175 +)) mice rescues respiratory, cognitive, and motor coordination deficits, and induces an anxiolytic e

176 tive mutant mice displayed severe ataxia and motor coordination deficits, but did not develop any tum

177 This MeCP2 overexpression line shows motor coordination deficits, heightened anxiety, and imp

178 ion immediately after injury coinciding with motor coordination deficits.

179 In addition, these mice also exhibit motor-coordination deficits, hypersensitivity to heat, n

180 The authors examined whether motor coordination difficulties assessed in childhood pr

181 cal symptoms and neuropathologies, including motor coordination disorder, cerebellar atrophy, neurona

182 t3gal2/3 double-null mice displayed impaired motor coordination, disturbed gait, and profound cogniti

183 eneous, characterized by loss of balance and motor coordination due to dysfunction of the cerebellum

184 There was no change in the normal motor coordination due to intracerebellar pretreatment w

185 s one such disease, characterized by loss of motor coordination due to the degeneration of cerebellar

186 al feedbacks elicited by a humanoid robot on motor coordination during a human-robot interaction.

187 ctions via CF6 neurons are not essential for motor coordination during either simple or complex locom

188 icited by a humanoid robot to modulate their motor coordination during human-robot interaction, partl

189 ctions via CF6 neurons are not essential for motor coordination during postural corrections.

190 al tasks that assessed timed motor speed and motor coordination (e.g., finger tapping, the Purdue Peg

191 es specific behavioral phenotypes, including motor coordination, episodic memory impairments, and syn

192 rsening of motor performance, with increased motor coordination errors.

193 needed for cerebellar synaptic function and motor coordination, explaining the shared cerebellar mot

194 ediates multifaceted sensory integration and motor coordination functions.

195 lex, Digiscan open field locomotion, rotarod motor coordination, hanging wire, footprint pathway, vis

196 ments, including hypolocomotion, deficits in motor coordination, impaired learning of new motor routi

197 MPTP-induced pathologies, exhibiting similar motor coordination impairment, dopaminergic neuron loss,

198 swim test, reduced prepulse inhibition, mild motor coordination impairments and reduced grip strength

199 pinal motoneuronal somatotopic organization, motor coordination implies interactions among distant sp

200 he brain and optic nerve, as well as in poor motor coordination in a pattern consistent with the obse

201 found sex-specific differences in weight and motor coordination in both mouse strains.

202 lel fiber-Purkinje cell (PF-PC) synapses and motor coordination in developing mice.

203 ature and extent of deficiencies in bimanual motor coordination in individuals with agenesis of the c

204 tion and for muscle strength, endurance, and motor coordination in mice in vivo.

205 ethanol while having no effect on the normal motor coordination in saline-treated control animals.

206 e immunotherapy leads to some improvement in motor coordination in SCA1 mice and to a modest increase

207 rkinje cells representing the source for all motor coordination in the cerebellar cortex.

208 social feedback had a facilitatory effect on motor coordination in the control participants compared

209 rtex, encode the timing signals required for motor coordination in their firing rate and activity pat

210 proposed to function as a timing device for motor coordination in which inferior olivary neurons act

211 nts favor a mechanical competition model for motor coordination in which the IFT motors exert a BBS p

212 unction and social recognition, and improves motor coordination in young male Mecp2-null (Mecp2(-/y))

213 behavioral phenotype revealed impairments in motor coordination, increased startle response to acoust

214 t serve the critical function of integrating motor coordination information with multimodal associati

215 expressed in the brain and is implicated in motor coordination, innate fear behavior, and seizure ge

216 Motor coordination is broadly divided into gross and fin

217 This aspect of motor coordination is controlled by inhibitory neurons i

218 Together these studies suggest that motor coordination is reliant on maintaining the correct

219 Motor coordination is supported by an array of highly or

220 The cerebellum, a crucial center for motor coordination, is composed of a cortex and several

221 ediated excitotoxicity, (iii) impairments in motor coordination, (iv) temporally distinct abnormaliti

222 While GoC inhibition is essential for normal motor coordination, little is known about the circuit dy

223 battery of neurobehavioral tests to evaluate motor coordination, locomotion, and cognitive function i

224 We discuss the possible motor coordination mechanism consistent with motor regul

225 dence that its function was critical for the motor coordination mechanism.

226 bellum, including sensory-motor integration, motor coordination, motor learning and timing.

227 ety (elevated plus maze and light/dark box), motor coordination (narrow bean traverse and gait), and

228 al structures that participate in this audio-motor coordination network in professional pianists and

229 This was accompanied by an improvement in motor coordination, neurological phenotypes, and increas

230 dy, we observed profound improvements in the motor coordination of AMI-treated N171-82Q HD model mice

231 This molecule did not impair the motor coordination of animals in the chimney test even a

232 hominids may provide an indication about the motor coordination of the tongue and reflect the evoluti

233 RGS9 knockout (KO) mice have decreased motor coordination on the accelerating rotarod and defic

234 contrast, F2 hybrid D2R-/- mice had impaired motor coordination on the rotarod that was corrected in

235 Although changes in motor coordination or anxiety cannot explain the dissoci

236 Problems with speech may reflect motor coordination or apraxia, problems with processing

237 Here we study motor coordination (or synchronisation) in a group of in

238 motion in the neonatal mouse or change gait, motor coordination, or grip strength in adult mice of bo

239 ficant impairments in neurological reflexes, motor coordination, pain sensitivity, and prepulse inhib

240 As a probe, we used a classic motor coordination paradigm exhibiting well described mo

241 rt at 5 and 7 years of age, with poorer fine motor coordination-particularly in the nondominant-at bo

242 ization between participants suggesting that motor coordination partly underlies patients' social int

243 t disorder, executive function deficits, and motor coordination problems.

244 ession domain was identified in a woman with motor-coordination problems, mild learning disability, a

245 sease with respect to weight loss, decreased motor coordination, Purkinje cell death, lipid storage,

246 preservation of executive function and fine motor coordination (r = 0.68 to 0.88).

247 Understanding cerebellar contributions to motor coordination requires deeper insight into how the

248 GlyR are involved in motor coordination, respiratory rhythms, pain transmissi

249 ssing short hairpin RNAs profoundly improved motor coordination, restored cerebellar morphology and r

250 movement but also hint at a wider variety of motor coordination roles.

251 Neuroinflammation, motor coordination (rotarod), and depressive behaviors (

252 These include poor motor coordination, sensory perceptual difficulties and

253 nstrument that assesses sensory integration, motor coordination, sequencing of complex motor acts, an

254 nt but not for sensorimotor gating, anxiety, motor coordination, several forms of learning or social

255 gative symptoms exhibited significantly more motor coordination signs and total NSS than patients wit

256 Alterations in learning, memory, motor coordination, social behavior, and stress response

257 r synchronization partners with a measure of motor coordination stability.

258 R4-/-) mice exhibited behavioral deficits in motor coordination, suggesting impaired cerebellar funct

259 deleted in only Purkinje cells had a loss of motor coordination that was almost identical to the tota

260 V408A/+ mice showed stress-induced loss of motor coordination that was ameliorated by acetazolamide

261 In addition to its well established role in motor coordination, the cerebellum has been hypothesized

262 hat climbing fibre signals are important for motor coordination, the mechanisms by which neurones in

263 Further 42 did not affect motor coordination up to doses of 1000 mg/kg, demonstrat

264 ct liability was determined by assessment of motor coordination using the rotarod test.

265 cerebral cortex, whereas age-related loss of motor coordination was correlated with oxidative molecul

266 Spontaneous locomotion and motor coordination was evaluated in young (5 month) and

267 le of cerebellar Kv3.1 and Kv3.3 channels in motor coordination was examined with an emphasis on the

268 Motor coordination was not altered.

269 No change in the normal motor coordination was noted when CHA administration was

270 sent in schizophrenia patients, whose social-motor coordination was similarly impaired in social and

271 ests of memory, executive function, and fine motor coordination, was correlated to magnetic resonance

272 To examine motor coordination, we purified neuronal transport vesic

273 her scores on tests of cognitive ability and motor coordination were associated with better performan

274 y, changes in activity-related behaviour and motor coordination were observed following CNO administr

275 Fall latencies in the rotorod test of motor coordination were unaffected by systemic administr

276 epp(-/-) mice lost weight and developed poor motor coordination when fed diets with selenium below 0.

277 Behavioral testing revealed normal motor coordination, whereas all mice receiving verum tre

278 engaged in bilateral sensory integration and motor coordination, whereas lower coordination across he

279 Jebsen-Taylor hand-function test, upper arm motor coordination with the finger-nose test, and grip s

280 contralesional paretic forelimb and improved motor coordination without influencing spontaneous locom