ライフサイエンスコーパス: mouse embryonic fibroblast

1 te in tumor cells and in the Ras-transformed mouse embryonic fibroblasts.

2 mic key feature of Tet1/Tet2 double-knockout mouse embryonic fibroblasts.

3 he real-time transport of beta-actin mRNA in mouse embryonic fibroblasts.

4 ifferentiation is increased in Id1-deficient mouse embryonic fibroblasts.

5 cell lines: human embryonic kidney cells and mouse embryonic fibroblasts.

6 ntoxic to normally dividing Schwann cells or mouse embryonic fibroblasts.

7 arental virus in monkey epithelial cells and mouse embryonic fibroblasts.

8 phagic cell death in Bax/Bak1 double-deleted mouse embryonic fibroblasts.

9 e are radioresistant compared with wild-type mouse embryonic fibroblasts.

10 reased survival in hyperosmotically stressed mouse embryonic fibroblasts.

11 e that PGC-1alpha modulates the secretome of mouse embryonic fibroblasts.

12 lar outcomes in Rab11a(null) blastocysts and mouse embryonic fibroblasts.

13 filament structures during reprogramming of mouse embryonic fibroblasts.

14 n both gene- and transcript-targeted primary mouse embryonic fibroblasts.

15 dent mechanisms, restrict HCV replication in mouse embryonic fibroblasts.

16 and sufficient to protect chromosome ends in mouse embryonic fibroblasts.

17 ssion in primary, senescent and immortalized mouse embryonic fibroblasts.

18 ime, the derivation of viable LIG3-deficient mouse embryonic fibroblasts.

19 quired for the polarization and migration of mouse embryonic fibroblasts.

20 and enhance copper accumulation in Ctr1(-/-) mouse embryonic fibroblasts.

21 e that adipogenesis is enhanced in Rnf146-/- mouse embryonic fibroblasts.

22 yl-dG with wild-type and pol kappa deficient mouse embryonic fibroblasts.

23 V) but not K-Ras(G12V) induced senescence in mouse embryonic fibroblasts.

24 pattern intermediate between pro-B cells and mouse embryonic fibroblasts.

25 n, and chromatin structure of Ku70-deficient mouse embryonic fibroblasts.

26 ntegration density in transcription units in mouse embryonic fibroblasts also correlated strongly wit

27 Utilizing mouse embryonic fibroblast and cancer cell line models,

28 We found that Plp2-deficient mouse embryonic fibroblast and human fibroblasts carryin

29 to block hypoxia-induced Fbln5 expression in mouse embryonic fibroblasts and 3T3 fibroblasts.

30 abolic homeostasis, we knocked down GRP78 in mouse embryonic fibroblasts and 3T3-L1 preadipocytes ind

31 imately 10000 regions of OG enrichment in WT mouse embryonic fibroblasts and approximately 18000 regi

32 We validate our method by imaging mouse embryonic fibroblasts and BON cells.

33 al and reduced colony formation of Fan1(-/-) mouse embryonic fibroblasts and bone marrow mesenchymal

34 expression is markedly reduced in TAp63-null mouse embryonic fibroblasts and brown adipose tissues an

35 ed respiratory dysfunction in Mfn2-deficient mouse embryonic fibroblasts and cardiomyocytes and in Pa

36 nhibited the Hh pathway in both Hh-dependent mouse embryonic fibroblasts and cultured cancer cells (I

37 found to be SIRT1-dependent in proliferating mouse embryonic fibroblasts and differentiating human SW

38 ependent of mammalian target of rapamycin in mouse embryonic fibroblasts and fibroblasts overexpressi

39 ption assays were performed with IQGAP1-null mouse embryonic fibroblasts and HEK293 cells with IQGAP1

40 Using chromatin immunoprecipitation in mouse embryonic fibroblasts and high-throughput sequenci

41 tors of focal adhesion and cell motility for mouse embryonic fibroblasts and human fibrosarcoma cells

42 osteopontin and other FN-type matrix in both mouse embryonic fibroblasts and human melanoma.

43 The addition of mouse embryonic fibroblasts and human tumor endothelial

44 otein levels were found in PSEN1/2-deficient mouse embryonic fibroblasts and in the cortex of forebra

45 t dependent on conditioning of the medium by mouse embryonic fibroblasts and is accelerated in the pr

46 s of mutant Kras homozygous and heterozygous mouse embryonic fibroblasts and lung cancer cells, that

47 rmacological or genetic inhibition of ILK in mouse embryonic fibroblasts and macrophages selectively

48 This phenotype was also seen in both mouse embryonic fibroblasts and mesangial cells.

49 control and tumor suppression, we generated mouse embryonic fibroblasts and mice expressing a mutant

50 Using genetic deficiencies in mouse embryonic fibroblasts and mouse liver, we identifi

51 K-Ras(G12V))-induced premature senescence in mouse embryonic fibroblasts and normal human bronchial e

52 , Eomes, and Ets2 is sufficient to reprogram mouse embryonic fibroblasts and post-natal tail-tip-deri

53 Cytogenetic analysis of mouse embryonic fibroblasts and pre-malignant B cells de

54 1alpha) stabilization in cultured Pink1(-/-) mouse embryonic fibroblasts and primary cortical neurons

55 adation of IP3R3 is accelerated in Pten(-/-) mouse embryonic fibroblasts and PTEN-null cancer cells.

56 When overexpressed in both mouse embryonic fibroblasts and rat OPCs (rOPCs), cell c

57 carcinogen-driven immortalization of primary mouse embryonic fibroblasts and recapitulates early step

58 nia virus replication in both HeLa cells and mouse embryonic fibroblasts and that its influence is ex

59 moted unrestrained p38 MAPK activity in both mouse embryonic fibroblasts and the heart, with no chang

60 rometric approach showed that ARH3-deficient mouse embryonic fibroblasts are characterized by a speci

61 e detail chromatin accessibility dynamics as mouse embryonic fibroblasts are reprogrammed into induce

62 We used mouse embryonic fibroblasts as a system to determine the

63 en uncovered new roadblocks in reprogramming mouse embryonic fibroblasts as pluripotent stem cells, d

64 mechanistic target of rapamycin signaling in mouse embryonic fibroblasts as well as in muscle and liv

65 a new system to delete FIP200 in transformed mouse embryonic fibroblasts as well as mammary tumor cel

66 In the case of mouse embryonic fibroblasts, BER of the Sp lesion is str

67 We show that, to perform these activities in mouse embryonic fibroblasts, both proteins competitively

68 ind that Orai1 is a dimer in resting primary mouse embryonic fibroblasts but displays variable stoich

69 iciently induces the cardiac gene program in mouse embryonic fibroblasts but not adult fibroblasts.

70 nternal structures of a mitochondrion from a mouse embryonic fibroblast cell line (NIH3T3) were visua

71 through cAMP-CREB signaling pathways both in mouse embryonic fibroblast cells and in urinary and repr

72 MG2 over TEM8 was further demonstrated using mouse embryonic fibroblast cells and mice deficient in t

73 s of 26S proteasomes purified from wild-type mouse embryonic fibroblast cells and those lacking Usp14

74 ntaneously (3T9) or virus-(SV40) transformed mouse embryonic fibroblast cells as targets.

75 Interestingly, in mouse embryonic fibroblast cells derived from CIZ1-null

76 anase-induced AKT phosphorylation was low in mouse embryonic fibroblast cells expressing a RAS intera

77 We investigated this question using mouse embryonic fibroblast cells expressing wild-type PK

78 Importantly, loss of Fyn protected mouse embryonic fibroblast cells from increased number o

79 Knockout of GSK3beta in mouse embryonic fibroblast cells increases expression of

80 optosis was not affected in SV40-transformed mouse embryonic fibroblast cells lacking Bak/Bax.

81 Although S187A mouse embryonic fibroblast cells showed normal prolifera

82 Mechanistic studies performed in mouse embryonic fibroblast cells showed that loss of nuc

83 ck-out but not VDAC1 and -3 double knock-out mouse embryonic fibroblast cells, confirming that Bcl-xL

84 ed the glycolytic products in both tumor and mouse embryonic fibroblast cells.

85 d-type (WT) and Bcl-xL knock-out (Bcl-xL-KO) mouse embryonic fibroblast cells.

86 y a minor fraction (30-40%) of the 26S in WT mouse embryonic fibroblast cells.

87 ng MyoD-induced differentiation of 4.1R(-/-) mouse embryonic fibroblast cells.

88 Mouse embryonic fibroblasts challenged with TPZ or Cu(OP

89 formation but is dispensable for kidney and mouse embryonic fibroblast ciliary formation.

90 R3/MyD88/IFN-beta promoter stimulator 1(-/-) mouse embryonic fibroblasts completely lacked antiviral

91 The content of 5-hmC is extremely low in mouse embryonic fibroblasts cultured in ascorbate-free m

92 Analysis of wounds and mouse embryonic fibroblast cultures showed that EMILIN-1

93 11/q-linked GPCRs to Rho was not impaired in mouse embryonic fibroblasts defective in all three RGS-c

94 nd of WT KRAS to rescue the growth defect of mouse embryonic fibroblasts deficient in all Ras genes.

95 Here we show that mouse embryonic fibroblasts deficient in Bax/Bak1 are re

96 in post-myocardial infarction hearts, and in mouse embryonic fibroblasts deleted for GSK-3beta.

97 Inhibitor kappaB kinase 2 (IKK2)-deficient mouse embryonic fibroblasts demonstrate abnormal morphol

98 affinity of derm A594 for MORs expressed in mouse embryonic fibroblasts derived from arrestin 1 and

99 Bone marrow cells and mouse embryonic fibroblasts derived from Fyn knockout mi

100 Reducing IP6K1 levels by RNAi or using mouse embryonic fibroblasts derived from ip6k1(-/-) knoc

101 ionally relevant to microtubule dynamics, as mouse embryonic fibroblasts derived from LRRK2 knock-out

102 Nphp5(-/-) mouse embryonic fibroblast developed normal cilia, and N

103 Interestingly, Msh3(-/-) mouse embryonic fibroblasts displayed increased chromati

104 and decreased senescence of hepatocytes and mouse embryonic fibroblasts, effects that were blocked b

105 tallin was upregulated in Tsc1-/- or Tsc2-/- mouse embryonic fibroblasts, Eker rat uterine leiomyoma-

106 ively, in Dhrs3(-/-) embryos, and Dhrs3(-/-) mouse embryonic fibroblasts exhibit reduced metabolism o

107 Spry1(-/-) and Spry2(-/-) double mutant mouse embryonic fibroblasts exhibited decreased cell mig

108 show that deletion of Ada3 from Ada3(FL/FL) mouse embryonic fibroblasts exhibited various chromosome

109 Whereas Bok(-/-) mouse embryonic fibroblasts exposed to thapsigargin, A23

110 levant doses; however, in the Ku70-deficient mouse embryonic fibroblasts, exposure to a high dose of

111 Tsc1(-/-) and Tsc2(-/-) mouse embryonic fibroblasts expressed higher uPA levels

112 nct culture platforms: feeder-free Matrigel, mouse embryonic fibroblast feeders, and Matrigel replate

113 4E-BP1 was evaluated in both mouse liver and mouse embryonic fibroblasts following combined disruptio

114 Calnexin deficiency as studied in mouse embryonic fibroblasts from calnexin(-/-)mice or in

115 doplasmic reticulum (ER) stress response) in mouse embryonic fibroblasts from Epm2a(-/-), Epm2b(-/-),

116 onferred resistance to cell death, and (iii) mouse embryonic fibroblasts from IFN receptor 1 knockout

117 Wnt signaling is significantly increased in mouse embryonic fibroblasts from mAnkrd6 knockout mice i

118 Here we used mouse embryonic fibroblasts from mice deficient in FAM13

119 Analysis of cultured mesoderm explants and mouse embryonic fibroblasts from null mutants shows that

120 Employing mouse embryonic fibroblasts from wild-type and RGS6(-/-)

121 ated reprogramming factor expression levels, mouse embryonic fibroblasts go through unique epigenetic

122 es induced in Cln3(Deltaex1) (-) (6)-derived mouse embryonic fibroblasts have visibly disorganized me

123 andard conditions on a medium conditioned by mouse embryonic fibroblasts in the presence of BMP4 and

124 e expression of HH target genes in Sufu(-/-) mouse embryonic fibroblasts, in which constitutive Gli a

125 mber of RhoA signaling-mediated processes in mouse embryonic fibroblasts, including stress fiber form

126 Loss of Smchd1 in transformed mouse embryonic fibroblasts increased tumor growth upon

127 ressor function because ablation of SRPK1 in mouse embryonic fibroblasts induces cell transformation.

128 letion can sensitize breast cancer cells and mouse embryonic fibroblasts into entering paclitaxel-ind

129 Myc (c-Myc) or Oct4 during reprogramming of mouse embryonic fibroblasts into iPSCs.

130 show that SV40 TAg-induced transformation in mouse embryonic fibroblasts is independent of activator

131 Further analyses of mouse embryonic fibroblasts isolated from Lzts2 knock-ou

132 Furthermore, mouse embryonic fibroblasts isolated from TRPM7 kinase-d

133 Complementation experiments in mouse embryonic fibroblasts lacking beta-arrestins combi

134 Here, we generated mice and mouse embryonic fibroblasts lacking both Dusp1 and Dusp4

135 Cyclin B1 induces chromosomal instability in mouse embryonic fibroblasts lacking both Tp53 and Rb1.

136 ld-type and NLS-mutated pol beta(R4S,K5S) in mouse embryonic fibroblasts lacking endogenous pol beta.

137 Mouse embryonic fibroblasts lacking the AMPKalpha1 and A

138 Using mouse embryonic fibroblasts lacking UGGT1 or those with

139 arly, experiments in cultured Oma1-deficient mouse embryonic fibroblasts link together impeded superc

140 Herein, we demonstrated that, in mouse embryonic fibroblasts, loss of LKB1 and transducti

141 cription factor EB (TFEB) in RagA/B knockout mouse embryonic fibroblasts, lysosomal acidification is

142 es E6/E7) disrupts circadian oscillations in mouse embryonic fibroblasts, measured using PER2::Luc dy

143 s the biogenesis and function of EVs using a mouse embryonic fibroblast (MEF) cell line that can be i

144 iferation was also observed in Mfn2-knockout mouse embryonic fibroblast (MEF) cells as compared with

145 Here we label the endogenous Pol II in mouse embryonic fibroblast (MEF) cells using the CRISPR/

146 381022) in enhancer H3K4 monomethylation in mouse embryonic fibroblast (MEF) cells.

147 Using an established mouse embryonic fibroblast (MEF) model combining p53 ina

148 Using mouse embryonic fibroblast (MEF) models that generate in

149 used an inducible Raptor and Rictor knockout mouse embryonic fibroblast (MEF) system to further defin

150 e H3 K36 trimethyltransferase SETD2 knockout mouse embryonic fibroblasts (MEF) cells.

151 Moreover, primary Rad18(-/-) mouse embryonic fibroblasts (MEF) retained robust Fancd2

152 Cyclin A2 deletion in oncogene-transformed mouse embryonic fibroblasts (MEF) suppressed tumor forma

153 arget genes in both 3T3-L1 pre-adipocyte and mouse embryonic fibroblasts (MEF) upon exposure to a mix

154 E359K mouse embryonic fibroblasts (MEF) were more sensitive to

155 IL-6 mRNA and protein secretion in wild-type mouse embryonic fibroblasts (MEF).

156 transformation using G0s2-null immortalized mouse embryonic fibroblasts (MEF).

157 y transfecting MNV-1 RNA into IFN-stimulated mouse embryonic fibroblasts (MEFs) and bone marrow-deriv

158 embryonic stem cells, but they were lower in mouse embryonic fibroblasts (MEFs) and differentiated ce

159 We characterized CENP-F(+/+) and CENP-F(-/-) mouse embryonic fibroblasts (MEFs) and found drastic dif

160 ation impairs the proliferative potential of mouse embryonic fibroblasts (MEFs) and is associated wit

161 on was severely abrogated in C/EBP-beta-null mouse embryonic fibroblasts (MEFs) and primary C/EBP-bet

162 trimethylation (H3K27me3) in both Pten null mouse embryonic fibroblasts (MEFs) and Pten null mouse p

163 These studies show that CRT-/- mouse embryonic fibroblasts (MEFs) and rat and human idi

164 lates Rb in Cdk4(-/-) pituitary AL cells and mouse embryonic fibroblasts (MEFs) and rescues their pro

165 Mouse embryonic fibroblasts (MEFs) and retinal cells fro

166 e generated PCBP2-deficient mice and primary mouse embryonic fibroblasts (MEFs) and showed that loss

167 olysis and represses fatty acid oxidation in mouse embryonic fibroblasts (MEFs) by targeting the AMP-

168 coding nonmitochondrial PB2 is attenuated in mouse embryonic fibroblasts (MEFs) compared with an isog

169 Here, we derive mouse embryonic fibroblasts (MEFs) deleted in all three

170 EGR1(-/-) mouse embryonic fibroblasts (MEFs) demonstrated lower su

171 AM20C was absent in the conditioned media of mouse embryonic fibroblasts (MEFs) derived from Fam20a k

172 Here we show that primary adipocytes and mouse embryonic fibroblasts (MEFs) derived from FTO over

173 We demonstrate that mouse embryonic fibroblasts (MEFs) derived from Hace1(-/

174 of AhR was NF-kappaB-dependent, as shown in mouse embryonic fibroblasts (MEFs) derived from Rel null

175 ical mechanics, we carried out studies using mouse embryonic fibroblasts (mEFs) derived from wild-typ

176 we show that positioning of mitochondria in mouse embryonic fibroblasts (MEFs) determines the shape

177 Mechanistically, Tmem30a-mutant mouse embryonic fibroblasts (MEFs) exhibited diminished

178 In this study, we show that, in mouse embryonic fibroblasts (MEFs) from Fut8(-/-) mice,

179 ts in cell cycle progression in immortalized mouse embryonic fibroblasts (MEFs) from PINK1(-/-) mice,

180 Using mouse embryonic fibroblasts (MEFs) from Tpcn1(-/-) and T

181 of Sall4, Nanog, Esrrb, and Lin28 (SNEL) in mouse embryonic fibroblasts (MEFs) generated high-qualit

182 Consistent with these results, Atf3(-/-) mouse embryonic fibroblasts (MEFs) had more aberrant chr

183 show that lysates from Nedd4-1 knockout (KO) mouse embryonic fibroblasts (MEFs) have significantly di

184 Evaluation of bs mouse embryonic fibroblasts (mEFs) identified enlarged G

185 on in both breast cancer (BC) cell lines and mouse embryonic fibroblasts (MEFs) induces oversized cel

186 letion can sensitize breast cancer cells and mouse embryonic fibroblasts (MEFs) into entering epirubi

187 imidine tract binding protein PTB to convert mouse embryonic fibroblasts (MEFs) into functional neuro

188 multifaceted effect on the reprogramming of mouse embryonic fibroblasts (MEFs) into induced pluripot

189 Proliferation of primary Ola1(-/-) mouse embryonic fibroblasts (MEFs) is impaired due to de

190 the G50DblKo virus was rescued by growth on mouse embryonic fibroblasts (MEFs) isolated from IFN-alp

191 We examined glutamine metabolism in mouse embryonic fibroblasts (MEFs) isolated from mice th

192 Here, we demonstrate that mouse embryonic fibroblasts (MEFs) isolated from Mrp4(-/

193 The Cc2d2a(-/-) mouse embryonic fibroblasts (MEFs) lack cilia, although

194 In the present study, we show that mouse embryonic fibroblasts (MEFs) lacking IP6K1 exhibit

195 Mature ADAM17 is present in mouse embryonic fibroblasts (mEFs) lacking iRhom2, and y

196 Using mouse embryonic fibroblasts (MEFs) lacking Nck, WIP, or

197 Primary mouse embryonic fibroblasts (MEFs) lacking the ARF tumor

198 First, quiescent mouse embryonic fibroblasts (MEFs) lacking Top2beta were

199 ventionally grown on mitotically inactivated mouse embryonic fibroblasts (MEFs) or feeder cells of hu

200 Mouse embryonic fibroblasts (MEFs) or primary adult card

201 Cebpg(-/-) mouse embryonic fibroblasts (MEFs) proliferate poorly an

202 from affected individuals and Cdk10-knockout mouse embryonic fibroblasts (MEFs) proliferated normally

203 Cebpg(-/-) mouse embryonic fibroblasts (MEFs) proliferated poorly,

204 Ectopic expression of DNMT3L in late-passage mouse embryonic fibroblasts (MEFs) recruited cytoplasmic

205 C1qbp(-/-) mouse embryonic fibroblasts (MEFs) resembled the human d

206 ction of PDAC cancer cells and SerpinB2(-/-) mouse embryonic fibroblasts (MEFs) resulted in increased

207 we report that Cdc14B knockout (Cdc14B(-/-)) mouse embryonic fibroblasts (MEFs) showed defects in rep

208 TOPFlash Wnt reporter assays in mouse embryonic fibroblasts (MEFs) showed general de-reg

209 the generations, and immortalized TIN2(+/DC) mouse embryonic fibroblasts (MEFs) showed telomere short

210 s, we compared gene expression in STAT3-null mouse embryonic fibroblasts (MEFs) stably expressing wil

211 MPK inhibitor to either mouse macrophages or mouse embryonic fibroblasts (MEFs) suppressed IFN-beta a

212 tebrate cells, maintain the DHS landscape of mouse embryonic fibroblasts (MEFs) synergistically.

213 By characterizing the mouse embryonic fibroblasts (MEFs) that express Csn8 at

214 onic day 18.5 BAT3(-/-) mouse embryos and in mouse embryonic fibroblasts (MEFs) through the modulatio

215 t of this transcription factor complex, from mouse embryonic fibroblasts (MEFs) to examine the role o

216 TNFalpha-treated Ikkbeta(-/-) mouse embryonic fibroblasts (MEFs) undergo apoptosis sig

217 Mouse embryonic fibroblasts (MEFs) were isolated from Sp

218 infectious EBOV derived from SOCS3 knockout mouse embryonic fibroblasts (MEFs) were significantly re

219 we generated and rescued SKAP-Hom-deficient mouse embryonic fibroblasts (MEFs) with WT SKAP-Hom, SKA

220 ed at 8 h after infection in W956IC-infected mouse embryonic fibroblasts (MEFs), and early viral prot

221 reduced in Ras(V12)-expressing p19(Arf) null mouse embryonic fibroblasts (MEFs), and overall Egr DNA-

222 overage and histone methylation occupancy in mouse embryonic fibroblasts (MEFs), induced pluripotent

223 Activation of GSK-3 in Keap1-null mouse embryonic fibroblasts (MEFs), or in human lung A54

224 In mouse embryonic fibroblasts (MEFs), Sirt6 knockout (KO)

225 of innate immune signaling and apoptosis in mouse embryonic fibroblasts (MEFs), T cells, and other c

226 Using knockout mouse embryonic fibroblasts (MEFs), we demonstrate that

227 g studies in Xenopus laevis egg extracts and mouse embryonic fibroblasts (MEFs), we show here that NC

228 nd after oxidative stress in caveolin-1-null mouse embryonic fibroblasts (MEFs), which do not express

229 is using an inducible knockout (KO) model of mouse embryonic fibroblasts (MEFs).

230 escence in wild-type but not caveolin-1 null mouse embryonic fibroblasts (MEFs).

231 ons in two different cell types, B cells and mouse embryonic fibroblasts (MEFs).

232 methyltransferase PRMT5 controls H4R3me2s in mouse embryonic fibroblasts (MEFs).

233 mily kinases in Src-/-, Yes-/-, Fyn-/- (SYF) mouse embryonic fibroblasts (MEFs).

234 n human cells and in Zmiz2 null (Zmiz2(-/-)) mouse embryonic fibroblasts (MEFs).

235 , using a SILAC approach, of PDGF-stimulated mouse embryonic fibroblasts (MEFs).

236 methyltransferase for PP2A, PP4, and PP6 in mouse embryonic fibroblasts (MEFs).

237 cancer cell lines, ex vivo tumor tissue, and mouse embryonic fibroblasts (MEFs).

238 slation initiation factor 2alpha (eIF2alpha) mouse embryonic fibroblasts (MEFs); moreover, ECD mRNA l

239 experiments using engineered Mcl-1 deficient mouse embryonic fibroblasts (MEFs, reliant only on Bcl-X

240 ll (RAW264.7 cells, primary macrophages, and mouse embryonic fibroblasts [MEFs]) apoptosis induced by

241 In a mouse embryonic fibroblast model, Drp1 C452F cells exhib

242 ment similarly inhibited nuclear import in a mouse embryonic fibroblast model.

243 sonance energy transfer; 3) in MPC1 depleted mouse embryonic fibroblasts, MPC1L rescues the loss of p

244 Using mouse embryonic fibroblast nuclei with normal or reduced

245 Expressing core in livers or mouse embryonic fibroblasts of ATGL(-/-) mice no longer

246 ied in the cytoskeletal fraction of purified mouse embryonic fibroblasts, of which 635 proteins were

247 In autophagy-deficient Atg5 or Atg3 null mouse embryonic fibroblasts, OFD1 accumulates at centrio

248 an occur by apoptosis (in Bax, Bak-deficient mouse embryonic fibroblasts or HeLa cells) or by necrosi

249 ally mimicked by inactivation of IR alone in mouse embryonic fibroblasts or in vivo in brown fat in m

250 tionally, we show that in kindlin-2 knockout mouse embryonic fibroblasts, overactivation of Ras, Akt,

251 Plk1 overexpression in mouse embryonic fibroblasts prepared from the transgenic

252 SIRT3-null mouse embryonic fibroblasts produced significantly more

253 consumption, and decreased ATP production in mouse embryonic fibroblasts, providing insights into the

254 ompared with wild-type cells, PTEN knock-out mouse embryonic fibroblasts (PTEN KO MEF) have 2-3-fold

255 Here we demonstrate that in mouse embryonic fibroblasts, reprogramming follows an or

256 HDAC6-null mouse embryonic fibroblasts rescued by the nonphosphoryl

257 presenilins in Drosophila larval brains and mouse embryonic fibroblasts, respectively.

258 f canonical autophagy: both WT and Atg5(-/-) mouse embryonic fibroblasts responded similarly.

259 nd in leukemias and solid tumors, in primary mouse embryonic fibroblasts resulted in proliferative ar

260 Deletion of USP9X in mouse embryonic fibroblasts resulted in significant down

261 However, paradoxically loss of LKB1 in mouse embryonic fibroblast results in resistance to onco

262 pletion of Spartan from conditional knockout mouse embryonic fibroblasts results in impaired lesion b

263 of Wrn, alone or in combination with Trf2 in mouse embryonic fibroblasts results in increased telomer

264 Transcriptome analysis using mouse embryonic fibroblasts revealed deregulation in the

265 In vitro investigations with mouse embryonic fibroblasts revealed factors, in additio

266 ficient mutants of vinculin in vinculin-null mouse embryonic fibroblasts revealed that PIP2 binding i

267 Further investigation using TAK1-deficient mouse embryonic fibroblasts revealed that TNF-alpha-indu

268 Furthermore, Fkbp10(-/-) mouse embryonic fibroblasts show retention of procollage

269 Rb1-deficient mouse embryonic fibroblasts showed increased levels of O

270 ection of ID8 mouse ovarian tumor cells with mouse embryonic fibroblasts showed that CD73 expression

271 overexpression of Hnf1a and Hnf4a in primary mouse embryonic fibroblasts, sometimes considered a surr

272 laminopathy patients and lamin A/C-deficient mouse embryonic fibroblasts stably expressing a broad pa

273 striking decrease seen in cultured Tsc2(-/-) mouse embryonic fibroblasts, suggesting one mechanism th

274 the migratory potential of MDM2(-/-)p53(-/-) mouse embryonic fibroblasts, suggesting that MTBP inhibi

275 ls overexpressing wild-type or mutant hCTR1, mouse embryonic fibroblasts that do or do not express CT

276 nctions are abrogated in lamin A/C-deficient mouse embryonic fibroblasts that recapitulate the defect

277 In contrast, in mouse embryonic fibroblasts the coding segment is deplet

278 th paclitaxel treatment using bim(-/-) MEFs (mouse embryonic fibroblasts), the bim(-/-) mouse breast

279 tional responses of embryonic stem cells and mouse embryonic fibroblasts to amber codon suppression.

280 We demonstrate that adaptation of mouse embryonic fibroblasts to cell culture results in a

281 l1, and Myt1l genes (BAM factors) to convert mouse embryonic fibroblasts to induced neuronal cells.

282 points to dissect direct reprogramming from mouse embryonic fibroblasts to induced neuronal cells.

283 ribing the reprogramming routes leading from mouse embryonic fibroblasts to induced pluripotency.

284 he resulting knock-out animals, we also used mouse embryonic fibroblasts to investigate the associate

285 onist Gamitrinib strongly sensitizes primary mouse embryonic fibroblasts to mPT and permeability tran

286 rine keratinocytes, human keratinocytes, and mouse embryonic fibroblasts to TNF-induced apoptosis.

287 Here, we take advantage of mouse embryonic fibroblasts transformed by oncogenic Dbl

288 in tumor cell lines, mouse lung tumors, and mouse embryonic fibroblasts undergoing RAS-induced senes

289 induction of iNOS decreases cell survival in mouse embryonic fibroblasts via mechanisms involving nit

290 In wild type and FAK knock-out mouse embryonic fibroblasts, we found by immunoblotting,

291 se drug inhibitors and presenilin mutants in mouse embryonic fibroblasts, we found that a mature gamm

292 For endogenous beta-actin genes in mouse embryonic fibroblasts, we observe that short-lived

293 Mitochondria in C452F mouse embryonic fibroblasts were depolarized and had red

294 larized recycling of alpha5beta1-integrin in mouse embryonic fibroblasts, which enables persistent fi

295 sis, we examined the Hh signaling pathway in mouse embryonic fibroblasts, which readily responds to t

296 The use of Ada3(FL/FL) mouse embryonic fibroblasts with deletion of Ada3 using

297 Mouse embryonic fibroblasts with genetic ablations of TS

298 Mouse embryonic fibroblasts with Ptpn11 GOF mutations sh

299 linositol (3,4,5)-trisphosphate (PIP3), from mouse embryonic fibroblasts with serum stimulation.

300 lear translocation was observed in wild-type mouse embryonic fibroblasts (WT MEFs), Tg2576 MEFs, and