ライフサイエンスコーパス: mucus layer

1 mum, devoid of inner membranes embedded in a mucus layer.

2 the mucosal lining, and the thickness of the mucus layer.

3 at are secreted by epithelial cells into the mucus layer.

4 dvantage for penetrating the viscous stomach mucus layer.

5 tes enhanced the retention in the intestinal mucus layer.

6 lls and abundantly secreted into the surface mucus layer.

7 cin denaturation and microbial access to the mucus layer.

8 r subdiffusive virions to traverse through a mucus layer.

9 tiating the retention of bacteria within the mucus layer.

10 ucin-degrading bacterium that resides in the mucus layer.

11 the main components of the gastrointestinal mucus layer.

12 wim through and colonize the viscous gastric mucus layer.

13 tract are in intimate contact with the outer mucus layer.

14 and limiting the association of VRE with the mucus layer.

15 ng the protection provided by the intestinal mucus layer.

16 ersistence of H. pylori in the human gastric mucus layer.

17 an "expanded" rather than more concentrated mucus layer, a prediction confirmed by electron microsco

18 development of NEC: reducing bacteria in the mucus layer, administering probiotic treatment, and bloc

19 d model of the glycocalyx layer, or adhesive mucus layer (AML), covered by mucus gel (luminal mucus l

20 between 042 and 042PicS258A in the lumen and mucus layer and adherent to tissue.

21 ia and bacterial components can traverse the mucus layer and contact host cells.

22 tly improved permeability through intestinal mucus layer and epithelia.

23 7BL/6 mice wherein V. cholerae colonizes the mucus layer and forms microcolonies in the crypts of the

24 underscored by decreased thickness of the OE mucus layer and increased numbers of immune cells within

25 ta, Proteobacteria were present in the inner mucus layer and invaded mucosal tissues.

26 ual intercourse, allows virions to cross the mucus layer and reach the epithelium in a short timefram

27 a are physically separated from villi by the mucus layer and their numbers controlled by mucus-embedd

28 ound in mucin, a component of the intestinal mucus layer and thus one of the prime adherence targets

29 ntraluminal digestive enzymes, the unstirred mucus layer, and a systemic ischemic-reperfusion injury.

30 robial peptide production, maturation of the mucus layer, and improved barrier function.

31 We investigated the roles of the intestinal mucus layer, and in particular Muc2, in development of e

32 eristalsis, fluid wash-out, viscosity of the mucus layer, and pH.

33 The intestinal mucus layer appears to function as a defensive barrier l

34 d barrier properties of the adherent gastric mucus layer are normally maintained by building-block st

35 achieved in part by the presence of a dense mucus layer at the epithelial surface and by the product

36 nteractions among the intestinal microbiota, mucus layer, bile acids, and mucosal immune responses, r

37 Entamoeba histolytica (Eh) colonizes the mucus layer by binding of the parasite's surface galacto

38 r less than 40 nm are able to pass through a mucus layer by passive Brownian motion.

39 s capable of dissolving the inner protective mucus layer by specific cleavages in the MUC2 mucin and

40 The mucus layer coating the airways is constantly moved alon

41 The mucus layer coating the pulmonary airways is moved along

42 A mucus layer coats the gastrointestinal tract and serves

43 s on the relative mucin concentration of the mucus layer compared with that of the periciliary layer;

44 stent intestinal colonization, and the cecal mucus layer contained high concentrations of MRSA.

45 The mucus layer covering the gastrointestinal (GI) epitheliu

46 The mucus layer covering the gastrointestinal tract is the f

47 rticularly true when pathogens encounter the mucus layer covering the respiratory tract.

48 ; and CF secretion osmotic pressures predict mucus layer-dependent osmotic compression of the pericil

49 obes may affect goblet cell dynamics and the mucus layer directly via the local release of bioactive

50 n in the colonic mucosa was mirrorred in the mucus layer fecal colonocytes isolated from AOM rat stoo

51 The potential positive role of the mucus layer for cellular uptake and the fate of the colo

52 dent microbiome is dependent on a protective mucus layer generated by goblet cells, impairment of whi

53 pure frictional coupling with the overlying mucus layer; hence, ciliary mixing most likely accelerat

54 er pylori persists deep in the human gastric mucus layer in a harsh, nutrient-poor environment.

55 ve within the microaerophilic surface of the mucus layer in CF lungs.

56 fails to explain the formation of a distinct mucus layer in health or why mucus clearance fails in di

57 susceptibility and highlight the role of the mucus layer in the development of CD.

58 A dense mucus layer in the large intestine prevents inflammation

59 H. felis colonized the mucus layer in the stomachs of Duoxa(-/-) mice to a grea

60 cells were mostly trapped within the surface mucus layer in WT mice.

61 y member of communities in the outer (loose) mucus layer, in the cecum and colon, starting at day 1 p

62 The gastrointestinal mucus layer is colonized by a dense community of microbe

63 The mucus layer is critical in limiting contact between host

64 ypothesis that growth of MRSA in the colonic mucus layer is required for establishment of intestinal

65 The dynamic nature of the mucus layer is shown.

66 as analyzed, considering that the intestinal mucus layer is the first defense against enteric pathoge

67 crypt regeneration, and also replenished the mucus layer, leading to amelioration of C. rodentium- an

68 s comprehensive insight into the dynamics of mucus layer maturation upon bacterial colonization of ge

69 The ASL comprises a superficial mucus layer (ML) overlying a periciliary fluid layer (PC

70 of functions in pathogen resistance such as mucus layer modifications and hydration, tight junction

71 of particular H. pylori strains in specific mucus layer niches.

72 The viscoelastic mucus layer of gastrointestinal tracts is a host defense

73 LipoLLA penetrated the mucus layer of mouse stomach, and a significant portion

74 EA both bound to a receptor localized in the mucus layer of the murine cecum.

75 ty member of mixed bacterial biofilms in the mucus layer of the streptomycin-treated mouse intestine.

76 The sputum (mucus) layer of the cystic fibrosis (CF) lung is a compl

77 ed fluid secretion mechanically disrupts the mucus layer or that toxins interfere with innate mucosal

78 The results show that the two mucus layers penetrate each other only marginally, and t

79 disease (IBD) are associated with a reduced mucus layer, potentially leading to dysbiosis associated

80 ng mucins, which are major components of the mucus layer protecting many epithelial surfaces, are clu

81 The intestinal mucus layer protects the epithelium from noxious agents,

82 The colonic mucus layer provides a potential niche for growth of VRE

83 The mucus layer provides an essential first host barrier to

84 These results suggest that the cecal mucus layer provides an important niche that facilitates

85 Removing the mucus layer reduced PCL transport by > 80%, to 4.8+/-0.6

86 s (IEC-Cosmc(-/y)) resulted in a compromised mucus layer, spontaneous microbe-dependent inflammation,

87 , for example, is lined by a firmly adherent mucus layer that is typically devoid of bacteria, follow

88 something that is achieved by a dense inner mucus layer that lines the epithelial cells.

89 imarily as single cells dispersed within the mucus layer that overlies the mouse cecal epithelium.

90 epithelial surface is protected by an inner mucus layer that the commensal microflora cannot penetra

91 tected by a highly viscoelastic and adhesive mucus layer that traps most foreign particles, including

92 ay surface liquid (ASL) consisting of both a mucus layer that traps, kills, and inactivates bacteria

93 did not improve the metabolic profile or the mucus layer thickness.

94 oatings that allow them to rapidly penetrate mucus layers through openings in the mucus mesh at rates

95 an inability to pass through the intestinal mucus layer to directly contact the epithelium.

96 stribution of inert nanoparticles within the mucus layers using an efficient replica exchange Monte C

97 s layer (AML), covered by mucus gel (luminal mucus layer) using a polymer lattice model and stochasti

98 duct exteriorization whereas the role of the mucus layer was tested via the enteral administration of

99 quired high concentrations of VRE within the mucus layer, whereas saline-treated mice did not.

100 l exhibited lower FAS levels and a decreased mucus layer, which could be restored with insulin treatm

101 e show that the small intestine has a porous mucus layer, which permitted the uptake of MUC2 by antig

102 ella propel bacteria through urine and along mucus layers, while type 1 fimbriae allow bacteria to ad

103 Zg16(-/-) mice have a distal colon mucus layer with normal thickness, but with bacteria clo