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1 nd was necessary for the evolution of animal multicellularity.
2 in basic processes associated with metazoan multicellularity.
3 pmental changes relevant to the evolution of multicellularity.
4 not cause potassium leakage failed to induce multicellularity.
5 ve played roles in the evolution of metazoan multicellularity.
6 rst the eukaryotic cell and later eukaryotic multicellularity.
7 ecological context during the transition to multicellularity.
8 ng the evolution of cell differentiation and multicellularity.
9 y have contributed to the advent of metazoan multicellularity.
10 tural novelties in Eukarya perhaps linked to multicellularity.
11 rons and ectopic expression at the origin of multicellularity.
12 for a long time was considered a hallmark of multicellularity.
13 ehavior during the earliest experiments with multicellularity.
14 Xdh gene in eukaryotes, before the origin of multicellularity.
15 ts that they are associated with the rise of multicellularity.
16 one of the early steps in the development of multicellularity.
17 ultrastructure when examining the origins of multicellularity.
18 erefore be an early step in the evolution of multicellularity.
19 e worm may have contributed to the advent of multicellularity.
20 during the initial step in the evolution of multicellularity.
21 s to have had an impact during the origin of multicellularity.
22 ther mechanistic studies on the emergence of multicellularity.
23 ms for understanding the evolution of animal multicellularity.
24 ping clusters may often be the first step to multicellularity.
25 not necessarily alongside, the emergence of multicellularity.
26 e challenges in how to organize and maintain multicellularity.
27 ulatory systems and the evolution of complex multicellularity.
28 organism, and this acts as a gating step for multicellularity.
29 ts, and rarer metazoan innovations linked to multicellularity.
30 key factor underlying the diverse origins of multicellularity.
31 l roles in the generation and maintenance of multicellularity.
32 ich evolved in tandem with the transition to multicellularity.
33 pression is essential for the maintenance of multicellularity.
34 oviding a necessary step in the evolution of multicellularity.
35 ic mechanisms, facilitated the transition to multicellularity.
36 y during the transition from single cells to multicellularity.
37 teria are a beautiful example of prokaryotic multicellularity.
38 select for the evolution of undifferentiated multicellularity.
39 PCD in microbes, including the evolution of multicellularity.
40 s was already in place at the dawn of animal multicellularity.
41 aiming to better understand genomic basis of multicellularity.
42 atterns as genomic and evolutionary basis of multicellularity.
43 cine algae coevolved with the acquisition of multicellularity.
44 ve demarcated the genetic toolkit for animal multicellularity, a select set of a few hundred genes fr
45 emical, and mechanistic basis of prokaryotic multicellularity, a topic that has garnered considerable
46 ment, expression pattern diversification and multicellularity, aiming to better understand genomic ba
47 Coming together amplifies the benefits of multicellularity and allows social clusters to collectiv
49 entally responsive molecular determinants of multicellularity and contribute to the natural morpholog
54 and facilitating evolutionary transitions to multicellularity and germ-soma differentiation in the vo
55 he major evolutionary transition to obligate multicellularity and had more cell types, a higher likel
56 al control mechanism governing the switch to multicellularity and raises the possibility that YlbF, Y
57 cadherins, which are essential for metazoan multicellularity and restricted to metazoans and their c
58 at differ only in the presence or absence of multicellularity and somatic differentiation, permitting
59 ion of orthologs of genes known to establish multicellularity and tissue architecture in metazoans.
60 to the understanding of natural evolution of multicellularity and to manipulating cell sedimentation
61 ordinated expression of strongly interacting multicellularity and unicellularity processes was lost i
62 complex RNA-silencing systems evolved before multicellularity and were a feature of primitive eukaryo
63 ation, the evolution of the eukaryotic cell, multicellularity, and the origin of human groups with la
64 s, the Palmophyllales, with a unique form of multicellularity, and typically found in deep water.
68 of living myocardium that retain the native multicellularity, architecture and physiology of the hea
70 lular relatives indicate that transitions to multicellularity are typically associated with increases
72 d of modular domains have evolved along with multicellularity as a method to facilitate increasing in
73 ns must be key players in the development of multicellularity because they are well positioned to for
74 nscription factors are key players in animal multicellularity, being members of the T-box family that
76 Integrin-mediated adhesion is as ancient as multicellularity, but it was not always as complex as it
77 tions have been identified in the context of multicellularity, but they have been treated very simila
78 gg, the social amoeba Dictyostelium achieves multicellularity by the aggregation of approximately 10(
81 ife histories, including social behavior and multicellularity, can only be understood in the appropri
84 lar, soma-producing strains, suggesting that multicellularity confers evolutionary stability to somat
87 nities do not satisfy the strict criteria of multicellularity developed by multi-level selection theo
89 and possible interplay between the origin of multicellularity, diversification of cyanobacteria, and
95 genes and their corresponding tRNAs, and in multicellularity genes and their tRNAs, suggesting the e
97 ot in laboratory strains, an indication that multicellularity has been lost during domestication of B
98 iridiplantae comprise unicellular algae, and multicellularity has evolved independently in the two cl
104 mergence of BMs coincided with the origin of multicellularity in animals, suggesting that they were e
108 osetta as a model system for studying simple multicellularity in choanoflagellates and provide an exp
112 en suggested that they evolved together with multicellularity in separate plant and animal lineages.
113 h a comparative study, comparing the form of multicellularity in species where groups are clonal (r =
114 (+)], governs the acquisition of facultative multicellularity in the budding yeast Saccharomyces cere
116 Among the best-studied ETIs is the origin of multicellularity in the green alga Volvox, a model syste
117 ystem for understanding the genetic basis of multicellularity including the initial formation of coop
121 llularity overlaps with the GOE, and whether multicellularity is associated with significant shifts i
128 s, the organizational principles of metazoan multicellularity may be more ancient than previously rec
130 elated to halogen metabolism, oxylipins, and multicellularity (microRNA processing and transcription
132 n ccs52A1 mutations dramatically enhance the multicellularity of sim mutants trichomes in double muta
133 s harbor features important in sexuality and multicellularity once believed to have originated in met
134 ransitions can be recursive (e.g., plastids, multicellularity) or limited (transitions that share the
136 peration and competition for the benefits of multicellularity promote the stable coexistence of unice
137 ll biology, we reason that the transition to multicellularity required modification of pre-existing m
141 omonas reinhardtii to conditions that favour multicellularity, resulting in the evolution of a multic
143 may constitute a barrier to the evolution of multicellularity since cell differentiation requires sen
144 ty that likely relate to the requirements of multicellularity such as the need to establish faithful
145 tonomous timing allows a trial commitment to multicellularity that external signals could extend.
147 early and formative step in the evolution of multicellularity, the evolution of cell cycle regulation
150 mechanisms evolved during the transition to multicellularity to control fundamental cellular process
153 in normal tissues, the evolution of complex multicellularity was not accompanied by reductions in mu
157 hanisms underlying the evolution of metazoan multicellularity, we sequenced and analysed the genome o
158 , reproductive division of labor, and clonal multicellularity while maintaining sufficient generality
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