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3 analyse the protein interaction network of a multidrug-resistant A. baumannii clinical strain (AB5075
5 increased transmission risk; however, having multidrug-resistant-A. baumannii and specific healthcare
6 a potential selective advantage possessed by multidrug-resistant-A. baumannii in this environment and
7 n-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Acinetobacter baumannii (MDR-AB) wer
9 ion therapy is deployed for the treatment of multidrug-resistant Acinetobacter baumannii, as it can r
11 y-onset infections; 66 isolates (50.0%) were multidrug resistant and, of 33 isolates tested for carba
12 The regimen could be effective against both multidrug-resistant and drug-susceptible tuberculosis in
14 ull gyrA and gyrB open reading frames in 240 multidrug-resistant and extensively drug-resistant tuber
15 utic options, particularly for patients with multidrug-resistant and extensively drug-resistant tuber
16 es in the world, and the increased number of multidrug-resistant and extremely drug-resistant strains
18 frequent cause of such infections, is often multidrug resistant, and chronically colonizes a sizable
20 transient hypoxia and the appearance of the multidrug resistant bacteria Staphylococcus simulans in
21 over new antibiotics or strategies to combat multidrug resistant bacteria, especially Gram-negative b
30 ntions, including drugs and vaccines against multidrug-resistant bacteria such as Neisseria gonorrhoe
31 lator-associated pneumonia, and infection by multidrug-resistant bacteria were independently associat
35 quantum dots (QDs) can kill a wide range of multidrug-resistant bacterial clinical isolates, includi
38 min antibiotics are used clinically to treat multidrug-resistant bacterial infections, but their poor
43 chanism when combined with AgNPs against the multidrug-resistant bacterium Salmonella typhimurium DT
44 ith the industrial production of eggs and of multidrug-resistant, bloodstream-invasive infection in A
45 more active in vitro than paclitaxel in the multidrug resistant breast cancer cell line LCC6-MDR.
46 illus fumigatus and emerging threats such as multidrug resistant Candida auris are also alarming.
49 ream, or surgical site infection caused by a multidrug-resistant (cases) or -sensitive (controls) mic
51 icrobial peptides displayed activity against multidrug-resistant clinical isolates of Escherichia col
54 cterium tuberculosis CNCTC My 331/88 and six multidrug-resistant clinically isolated strains of M. tu
56 of sequence type 131 (ST131) are a pandemic multidrug resistant clone associated with urinary tract
58 e of serotype 35B disease and emergence of a multidrug-resistant clone reported in this issue of the
59 R genes associated with clinically important multidrug-resistant clones and epidemic plasmids, in Ame
62 thin the outbreak (4.7%), including within a multidrug-resistant cluster that carried a rare rpoB mut
63 munity-based, commensal population underlies multidrug-resistant E. cloacae infections within hospita
64 tudy, we analysed a systematic collection of multidrug-resistant E. cloacae isolated between 2001 and
65 n testing of fosfomycin was performed on 649 multidrug-resistant E. coli clinical isolates collected
68 l envelope; these include metallopeptidases, multidrug-resistant efflux (MDR) pumps, TonB-dependent r
69 mycin has become a front-line antibiotic for multidrug-resistant Enterococcus faecium bloodstream inf
70 iotics reduced selective pressures favouring multidrug-resistant epidemic ribotypes and was associate
71 iotics reduced selective pressures favouring multidrug-resistant epidemic ribotypes and was associate
78 CI, 0.32-1.40), bacteriuria associated with multidrug-resistant gram-negative bacilli (9 vs 24 episo
80 efficacy of strategies for the prevention of multidrug-resistant gram-negative bacteria (MDR-GNB) in
81 olderia cepacia complex (Bcc) are a group of multidrug-resistant gram-negative bacteria rarely report
82 line of defence in serious infections due to multidrug-resistant Gram-negative bacteria, but their us
85 valuated against panels of tetracycline- and multidrug-resistant Gram-positive and Gram-negative path
86 Acinetobacter pittii are a frequent cause of multidrug-resistant, healthcare-associated infections.
88 examined the evolutionary history of leading multidrug resistant hospital pathogens, the enterococci,
91 omial pneumonia, is a versatile and commonly multidrug-resistant human pathogen for which further ins
92 th or without reduced ejection fraction, and multidrug-resistant hypertension (RHT) are major worldwi
94 w therapeutic targets are required to combat multidrug resistant infections, such as the iron-regulat
96 eatment of several human diseases, including multidrug-resistant infections and genetic disorders.
97 nfective strategy has the potential to treat multidrug-resistant infections and limit the emergence o
98 s used in the last line of defense to combat multidrug-resistant infections by Gram-negative bacteria
99 sistance mutations shape the pathobiology of multidrug-resistant infections has the potential to driv
101 is a significant contributor to recalcitrant multidrug-resistant infections, especially in immunocomp
106 y profiling their antiviral efficacy against multidrug-resistant influenza A viruses, in vitro drug r
108 nya, and Tanzania (both sites combined), and multidrug-resistant iNTS was isolated in Burkina Faso (b
112 sticity and speed of evolutionary changes in multidrug-resistant K. pneumoniae, demonstrating the hig
114 to human cell lines, and are active against multidrug-resistant M. tuberculosis strains, indicating
116 much superior to that of doxorubicin in the multidrug resistant MCF-7/ADR xenografted nude mice.
117 ests are urgently needed for the analysis of multidrug resistant (MDR) and extensively drug resistant
118 d significantly reduced drug efflux by model multidrug resistant (MDR) breast cancer cell lines (MCF-
121 ted for their antibacterial activity against multidrug resistant (MDR) Gram-positive and Gram-negativ
123 77.7% (28/36) of clinical isolates indicated multidrug resistant (MDR) patterns, 50% (18/36) indicate
124 is, resistance categories were predefined as multidrug resistant (MDR), isoniazid resistant, rifampic
125 of ceftolozane-tazobactam resistance during multidrug resistant (MDR)-Pseudomonas aeruginosa infecti
130 he highest incidences of DR-TB, particularly multidrug-resistant (MDR) and extensively drug-resistant
132 s are threatened by the increasing burden of multidrug-resistant (MDR) and extensively drug-resistant
133 onsumption, incidence density of Candida and multidrug-resistant (MDR) bacteria bloodstream infection
134 s known about the excess mortality caused by multidrug-resistant (MDR) bacterial infection in low- an
138 re are more cases of isoniazid-resistant and multidrug-resistant (MDR) disease than are identified.
139 unctional CRISPR-Cas systems are absent from multidrug-resistant (MDR) Enterococcus faecalis, which o
140 um of activity of these antibiotics includes multidrug-resistant (MDR) gram-negative bacteria (GNB),
144 in the Shigellae, particularly as a specific multidrug-resistant (MDR) lineage of Shigella sonnei (li
146 ntial association between TTSS genotypes and multidrug-resistant (MDR) profiles, and how this interac
148 nd die from tuberculosis (TB) each year, and multidrug-resistant (MDR) strains of TB are increasingly
149 ion model to follow a hypothetical cohort of multidrug-resistant (MDR) TB patients under different be
151 sis that were due to inadequate treatment of multidrug-resistant (MDR) tuberculosis (i.e., acquired r
152 erculosis (LTBI) after contact to infectious multidrug-resistant (MDR) tuberculosis (TB) are lacking
154 al approach to assess recent transmission of multidrug-resistant (MDR) tuberculosis and identify pote
156 efficacy and safety in drug-susceptible and multidrug-resistant (MDR) tuberculosis during the first
159 A novel, shorter-course regimen for treating multidrug-resistant (MDR) tuberculosis was recently reco
163 g-sensitive (MIC = 0.012 muM; SI >/= 16000), multidrug-resistant (MDR), and extensively drug-resistan
164 phenicol, and trimethoprim-sulfamethoxazole (multidrug resistant [MDR]) was limited to Typhi isolates
165 otgun sequencing of all stools, we find that multidrug-resistant members of the genera Escherichia, K
166 st planktonic and biofilm forms of different multidrug resistant microorganisms, we present here the
171 osis treatments, particularly in the case of multidrug-resistant Mycobacterium tuberculosis (Mtb).
174 s with Mycobacterium abscessus, a species of multidrug-resistant nontuberculous mycobacteria, are eme
177 compliance with prevention bundles impacted multidrug-resistant organism (MDRO) infections in Thai h
178 m difficile (OR 1.02, 95% CI 0.34-3.01), and multidrug-resistant organism (OR 1.06, 95% CI 0.42-2.71)
179 2 weeks' gestation or younger; prevalence of multidrug-resistant organism colonisation; and length of
180 Mycobacterium abscessus is a fast-growing, multidrug-resistant organism that has emerged as a clini
187 Patients admitted to hospital can acquire multidrug-resistant organisms and Clostridium difficile
190 h the aim to decrease selective pressure for multidrug-resistant organisms in order to preserve the u
192 day mortality, and mortality associated with multidrug-resistant organisms were significantly lower i
193 f clinical cultures that tested positive for multidrug-resistant organisms, blood culture contaminati
194 he ability of bacterial pathogens, including multidrug-resistant organisms, to colonize and subsequen
201 evaluated for antimalarial activity against multidrug-resistant P. yoelii in mice in the dose range
204 eptibility testing (AFST) of the potentially multidrug-resistant pathogen Candida glabrata against an
207 n "out of the box" therapeutic treatment for multidrug resistant pathogenic bacterial infections.
214 e shown that induction of MarA can lead to a multidrug resistant phenotype at the population level.
215 ne artemisinin combination therapy (ACT) for multidrug-resistant Plasmodium falciparum malaria in Cam
217 ons, antibiotic resistance, and particularly multidrug-resistant profiles, is certainly of paramount
219 ith the adhesin MAM7 to a burn infected with multidrug-resistant Pseudomonas aeruginosa substantially
223 eus, methicillin-resistant S. aureus (MRSA), multidrug-resistant S. aureus (MDRSA), absence of scn (p
229 otic resistance spreads among bacteria, with multidrug-resistant staphylococci and streptococci infec
232 irds and, in one case, identical to a highly multidrug resistant strain isolated from a human child.
233 compounds possess potent activity against a multidrug resistant strain of P. falciparum and arrest p
234 ones, beta-lactam/beta-lactamase inhibitors, multidrug resistant strains and carbapenem-resistant Ent
237 ns are a large proportion of HAI agents, and multidrug-resistant strains of Klebsiella pneumoniae, a
238 creasingly complicated with the emergence of multidrug-resistant strains of Mycobacterium tuberculosi
239 ed by the HIV/AIDS pandemic and emergence of multidrug-resistant strains of Mycobacterium tuberculosi
240 t in antimicrobial activity observed against multidrug-resistant strains of Pseudomonas aeruginosa an
242 gainst Mycobacterium tuberculosis, including multidrug-resistant strains, and some species of nontube
243 its over monotherapy, it may also select for multidrug-resistant strains, particularly during long-te
247 uctions into Africa, all from Asia, involved multidrug-resistant sublineages that replaced antibiotic
252 have great potential to limit the spread of multidrug-resistant tuberculosis (MDR-TB) and extensivel
253 It is estimated that 33,000 children develop multidrug-resistant tuberculosis (MDR-TB) each year.
254 patients successfully treated for pulmonary multidrug-resistant tuberculosis (MDR-TB) in Tomsk, Russ
257 antibiotics recommended for the treatment of multidrug-resistant tuberculosis (MDR-TB) patients.
259 e the etiology of "hotspots" of concentrated multidrug-resistant tuberculosis (MDR-tuberculosis) risk
260 focus on antibiotics that are active against multidrug-resistant tuberculosis and Gram-negative bacte
261 improve treatment outcomes for patients with multidrug-resistant tuberculosis and prevent the spread
264 ing percentage reduction in the incidence of multidrug-resistant tuberculosis by 2024 compared with c
265 system increased referrals from presumptive multidrug-resistant tuberculosis cases by >10-fold, with
267 idrug-resistant tuberculosis will be primary multidrug-resistant tuberculosis compared with only 15%
268 ovements in treatment for drug-sensitive and multidrug-resistant tuberculosis could reduce the number
270 en has potential to substantially lessen the multidrug-resistant tuberculosis epidemic, but this effe
271 en has potential to substantially lessen the multidrug-resistant tuberculosis epidemic, but this effe
272 rge public health and societal implications, multidrug-resistant tuberculosis has been long regarded
273 ns in the primary analysis, the incidence of multidrug-resistant tuberculosis in 2024 would be 3.3 (9
275 of isoniazid resistance, a 152% increase in multidrug-resistant tuberculosis incidence, a 242% incre
277 ay, 2016, WHO endorsed a 9 month regimen for multidrug-resistant tuberculosis that is cheaper and pot
278 cal agents used to halt the progression from multidrug-resistant tuberculosis to extensively resistan
279 rld Health Organization category 5 drugs for multidrug-resistant tuberculosis using a 7H9 broth micro
280 CWs in 3 district hospitals with specialized multidrug-resistant tuberculosis wards in KwaZulu-Natal,
282 each of confirmed tuberculosis and suspected multidrug-resistant tuberculosis) to a randomly allocate
283 ence, a 242% increase in prevalent untreated multidrug-resistant tuberculosis, and a 275% increase in
284 Secondary outcomes were missed tuberculosis, multidrug-resistant tuberculosis, and comorbidities with
285 n settings with more ongoing transmission of multidrug-resistant tuberculosis, but results were other
286 d-resistant tuberculosis is more common than multidrug-resistant tuberculosis, it has been much less
287 ope is complicated by the high prevalence of multidrug-resistant tuberculosis, low rates of drug susc
288 he public sector contributed 87% of acquired multidrug-resistant tuberculosis, related to irregular a
294 luating new agents/regimens for treatment of multidrug-resistant tuberculosis; and (3) evaluating saf
295 ensitive tuberculosis; improved treatment of multidrug-resistant tuberculosis; and expansion of acces
296 critical implications for drug-targeting in multidrug-resistant tumors where a stressful micro-envir
297 Broad-spectrum antibiotics for recurrent multidrug-resistant urinary tract infections (UTIs) disr
299 tion, and only two cases of infection with a multidrug-resistant virus have been reported under adequ
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