ライフサイエンスコーパス: multifactorial

1 is are not fully elucidated but appear to be multifactorial.

2 ns for this are unknown and are likely to be multifactorial.

3 nsitivity of a PTC-containing mRNA to NMD is multifactorial.

4 fety, and the reasons for these deficits are multifactorial.

5 etween diabetes and psychosis is complex and multifactorial.

6 ss in thrombolysis for acute stroke has been multifactorial.

7 delines for treatment are individualized and multifactorial.

8 of growth failure in the setting of CKD are multifactorial.

9 ve tuberculosis disease has been shown to be multifactorial.

10 one loss after bariatric surgery is probably multifactorial.

11 ion of increased pressure in solid tumors is multifactorial.

12 ity of cases the genetic basis appears to be multifactorial.

13 The etiology of varicoceles is probably multifactorial.

14 ible or treatable causes because it is often multifactorial.

15 rated atherosclerotic process is complex and multifactorial.

16 The cause of renal transplant lithiasis is multifactorial.

17 gimens in noninfectious pediatric uveitis is multifactorial.

18 underlying racial disparities in cancer are multifactorial.

19 ving emergence of resistance are complex and multifactorial.

20 gonism are poorly understood but most likely multifactorial.

21 Anabolic resistance is thus multifactorial.

22 bodies (DLB) and Parkinson disease (PD) are multifactorial.

23 The mechanisms underlying secondary MR are multifactorial; accurate imaging assessment of secondary

24 iated with increased risk of IHD or MI after multifactorial adjustment for chronological age and well

25 The reasons for delay were multifactorial: administrative (police case recordings,

26 g of the molecular mechanisms underlying its multifactorial aetiology.

27 Dry eye disease (DED) is multifactorial, affecting 5-34 % of the global adult pop

28 Immunosenescence is the multifactorial age-associated immune deteriorization tha

29 Alzheimer's disease (AD) comprises multifactorial ailments for which current therapeutic st

30 ed with the risk of work disability, but few multifactorial algorithms exist to identify individuals

31 In multifactorial analyses, only prior ACE-I treatment rema

32 Multifactorial analysis of bacterial community structure

33 ume and anatomic position were assessed with multifactorial analysis of variance followed by posthoc

34 We undertook a multifactorial analysis using the Cox proportional hazar

35 hepatic encephalopathy (HE) in cirrhosis is multifactorial and ammonia is thought to play a key role

36 The reasons for the IMD increase are multifactorial and are influenced by increased virulence

37 k of blood-borne viral infection is probably multifactorial and associated with low socioeconomic sta

38 er orthotopic heart transplantation (OHT) is multifactorial and can be an indicator of graft rejectio

39 Resistance to these agents is multifactorial and can be via one or a combination of ta

40 he pathogenesis of atopic dermatitis (AD) is multifactorial and complex.

41 thogenesis of diverticular disease is likely multifactorial and complex.

42 The mechanisms guiding HTS formation are multifactorial and complex.

43 The reasons for differences are multifactorial and could not be determined by this study

44 related cataracts, and the visual outcome is multifactorial and dependent on postoperative visual reh

45 Causation is multifactorial and exogenous or endogenous exposures, ge

46 Alzheimer's disease (AD) is a multifactorial and fatal neurodegenerative disorder for

47 inicians acknowledge that type 2 diabetes is multifactorial and has heterogeneous characteristics, bu

48 Etiologies of impaired male fertility are multifactorial and include hypogonadism, erectile dysfun

49 The pathogenesis of infections is multifactorial and includes hypogammaglobulinemia, conve

50 The basis for this is multifactorial and includes the emergence of epidemic cl

51 The reasons for this disparity are multifactorial and incompletely understood.

52 The cause of recurrence is likely multifactorial and individualized to each patient.

53 Periodontitis is a multifactorial and infectious disease that may result in

54 ome insects to tolerate low temperatures are multifactorial and involve several physiological systems

55 y significant exercise intolerance, which is multifactorial and involves skeletal muscle alterations.

56 failure with preserved ejection fraction are multifactorial and largely related to body mass index, l

57 betes are not completely understood, but are multifactorial and likely include effects of obesity, hy

58 ahepatic effects of HCV infection are likely multifactorial and may include endocrine effects, HCV re

59 oved away from targeting a specific organ to multifactorial and multidisciplinary individualized appr

60 Multifactorial and multigenerational implications of tot

61 Pathogenesis of gallstones (GS) is multifactorial and multiple genetic and environmental fa

62 Reasons for readmission were multifactorial and not easily categorized into mutually

63 because most believe that quality of care is multifactorial and not represented by an individual's mo

64 rlying mechanism of insulin sensitization is multifactorial and not through the canonical insulin/Akt

65 The causes of steroid-resistant asthma are multifactorial and result from complex interactions of g

66 nt disparities in cardiovascular disease are multifactorial and span from the individual level to the

67 The pathogenesis is multifactorial and the disease may occur at any age.

68 e pathophysiology of IBS is considered to be multifactorial and the exact cause of the disease remain

69 The causative mechanisms are multifactorial and there are no effective treatments for

70 ogy of benign prostatic hyperplasia (BPH) is multifactorial, and chronic inflammation plays a pivotal

71 Lung cancer etiology is multifactorial, and growing evidence has indicated that

72 atric venous thromboembolic disease (VTE) is multifactorial, and in most children, 1 or more clinical

73 e role of p110alpha in tumor angiogenesis is multifactorial, and includes regulation of proliferation

74 athogenesis of S. agalactiae UTI is complex, multifactorial, and influenced by virulence effects of C

75 the age of 10 years, the disease is complex, multifactorial, and lifelong, and affects nutrition and

76 However, age-related changes are likely multifactorial, and the relationship between neural chan

77 emia (IDA), anemia of inflammation (AI), and multifactorial anemia (IDA+AI).

78 Here, we analyzed renal endpoints of the Multifactorial Approach and Superior Treatment Efficacy

79 is a polymicrobial disease, which requires a multifactorial approach for its prevention and treatment

80 commitment, it might be useful to consider a multifactorial approach that highlights building trust i

81 mprovement strategies (eg, case management), multifactorial assessment and treatment (eg, comprehensi

82 ent-level quality improvement strategies and multifactorial assessment and treatment relative to usua

83 These results illustrate the multifactorial basis of genetic interactions involving t

84 These findings confirm the multifactorial basis of migraine and might allow new pro

85 A multifactorial behavioral intervention emphasizing spice

86 natures of TGF-beta and Notch pathways, with multifactorial biological outcomes.

87 reasons for this change in pathogenesis are multifactorial but likely include mutations that have ar

88 ive paucity of new clinical tools for HF are multifactorial but likely include the need to recognize

89 The reasons for this are multifactorial but may include differences in comorbidit

90 Cyclosporine A-induced nephrotoxicity is multifactorial but oxidative stress has a critical role

91 The pathogenesis of BPD is multifactorial, but all triggers cause pulmonary inflamm

92 Causes of NSPS are multifactorial, but may include parental influences.

93 The pathophysiology of CRPC is clearly multifactorial, but most often, androgen receptor (AR) u

94 The reasons for this trend are multifactorial, but of primary concern is the high cost

95 Exercise intolerance is multifactorial, but pulmonary vascular resistance probab

96 vidence in the field and help understand the multifactorial cause of bone loss in this group of indiv

97 In view of the complex multifactorial causes of delirium, multicomponent non-ph

98 ile and quantitative approach to investigate multifactorial cell-stress emergent from diverse bioinst

99 This multifactorial character hides essential enthalpy contri

100 Multifactorial ChIP-seq data integration from the endome

101 The role of retinol in the prevention of multifactorial chronic diseases remains uncertain, and t

102 Aqueous tear-deficient dry eye is a multifactorial chronic disorder in which the lacrimal gl

103 The development of inhibitors is a multifactorial complication involving environmental and

104 upstream kinases of ERK1/2 signaling, alters multifactorial components of the innate and adaptive imm

105 t Lip and/or Palate (NSCLP) is regarded as a multifactorial condition in which clefting is an isolate

106 Obesity is a multifactorial condition influenced by genetics, lifesty

107 disease unclassified (IBDU) is a complex and multifactorial condition with increasing incidence.

108 Asthma and obesity are chronic multifactorial conditions that are associated with gene-

109 cause underlying these differences is likely multifactorial, considerable evidence supports an import

110 This suggests that anxiety is a multifactorial construct phenotypically and aetiological

111 We found that spatial anxiety is a multifactorial construct, including two components: navi

112 ions that relate to just one aspect of these multifactorial constructs.

113 plasticity and behavioral performance in the multifactorial context of DS.

114 urs through haploinsufficiency, and point to multifactorial control of red cell mass by PHD2.

115 Multifactorial data analysis of DeltaCt values identifie

116 We show this is likely to be the result of multifactorial deficits in anabolic hormones and blunted

117 Using a multifactorial design, the effect of soy lecithin (L) an

118 Multifactorial determinants of breastfeeding need suppor

119 Deciphering the multifactorial determinants of tumor progression require

120 modern approach to obesity acknowledges the multifactorial determinants of weight gain and the healt

121 (CdLS), are characterized by broad spectrum, multifactorial developmental anomalies.

122 torial input of environmental stimuli into a multifactorial developmental output that manifests itsel

123 all randomized controlled trials evaluating multifactorial dietary interventions in adults with chro

124 L1B) +3954C/T (rs1143634) was assessed using multifactorial dimensionality reduction analysis.

125 t CSE outperforms existing methods including multifactorial dimensionality reduction and Bayesian epi

126 Migraine is a common, multifactorial, disabling, recurrent, hereditary neurova

127 Given that SSc is a multifactorial disease caused by both genetic and enviro

128 Cardiac hypertrophy is a multifactorial disease characterized by multiple molecul

129 Parkinson's disease (PD) is a complex multifactorial disease characterized by the progressive

130 Metabolic syndrome (MetS) is a multifactorial disease cluster that consists of dyslipid

131 Alzheimer's disease (AD) is a complex, multifactorial disease in which different neuropathologi

132 This multifactorial disease manifests as a spectrum of clinic

133 Chronic rhinosinusitis (CRS) is a prevalent multifactorial disease process in which bacteria are bel

134 Chronic lung allograft dysfunction is a multifactorial disease that remains irreversible and unp

135 st genome-wide methylation studies (EWAS) of multifactorial disease traits use targeted arrays or enr

136 Cancer is a multifactorial disease which involves complex genetic mu

137 KC is known to be a multifactorial disease with an elusive pathogenesis.

138 Age-related macular degeneration (AMD) is a multifactorial disease with genetic and environmental fa

139 It is a multifactorial disease with several risk factors, of whi

140 Age-related macular degeneration (AMD), a multifactorial disease with variable phenotypic presenta

141 Male osteoporosis is a multifactorial disease, although it is often in part rel

142 zheimer's disease: inseparable partners in a multifactorial disease.

143 wn about the mechanisms driving this complex multifactorial disease.

144 searchers mistakenly consider caries to be a multifactorial disease; they also concentrate mainly on

145 Increased molecular understanding of multifactorial diseases paves the way for novel therapeu

146 the progression or the development of these multifactorial diseases through diet is an emerging and

147 monogenic neurological disorders and complex multifactorial diseases, including Alzheimer's disease.

148 Multifactorial diseases, including autoimmune juvenile i

149 orn errors of metabolism and the more common multifactorial diseases.

150 etic variants involved in complex traits and multifactorial diseases.

151 ic disease or are incriminated in polygenic, multifactorial diseases.

152 d be used to address the polygenic nature of multifactorial diseases.

153 y may lie with the recognition that OSA is a multifactorial disorder and that OAs may affect more tha

154 g mitochondrial function are associated with multifactorial disorders including kidney disease.

155 e gene and the development of more prevalent multifactorial disorders including Parkinson's disease a

156 hared can identify overlapping etiologies of multifactorial disorders.

157 d multiplex families, are of innate value in multifactorial disorders.

158 arkable progress in our understanding of the multifactorial drivers of hippocampal aging and cognitiv

159 Screening of children for multifactorial dyslipidemia has not been evaluated in ra

160 Multifactorial dyslipidemia, characterized by elevated t

161 lemia, and 1 review focused on screening for multifactorial dyslipidemia.

162 s (HAT) after liver transplantation (LT) are multifactorial, early HAT (E-HAT) remains pertinent comp

163 The results indicated a multifactorial effect of the HLA-DR4 transgene on develo

164 munity conferred by 2D6 IgA is the result of multifactorial effects on V. cholerae, including aggluti

165 This case presented with multifactorial etiology.

166 ong the most common human birth defects with multifactorial etiology.

167 Therefore, we propose that more multifactorial experiments should be considered in study

168 Thrombocytopenia is a common, multifactorial, finding in ICU.

169 uting factors, underlining the importance of multifactorial fracture risk assessment.

170 rythematosus has a complex environmental and multifactorial genetic basis.

171 hod will enable high-throughput profiling of multifactorial genetic combinations that regulate phenot

172 re males than females; consequently, under a multifactorial genetic hypothesis, females are affected

173 computational challenge that the effects of multifactorial genetic perturbations should be decoded s

174 ynamics of eight abundant plant species in a multifactorial global change experiment in alpine tundra

175 that severe manifestations of human DILI are multifactorial, highly associated with combinations of d

176 l, and circumstantial evidence, we present a multifactorial hypothesis that has potential direct impl

177 dden infant death syndrome is believed to be multifactorial, ie, occurs in infants with underlying bi

178 Psychiatric disorders are complex multifactorial illnesses involving chronic alterations i

179 ery cohort of melanoma patients suggest that multifactorial immune signatures have the potential to a

180 hough PN-associated liver disease (PNALD) is multifactorial in etiology, components of soybean oil li

181 he efficacy of a therapeutic intervention is multifactorial in nature and in many cases the source of

182 o hypoperfusion of the spinal cord, which is multifactorial in origin, including small aortic calibre

183 Obesity is recognized as being multifactorial in origin, involving both genetic and env

184 Q to detect HIV-1 infection was frequent and multifactorial in origin.

185 It is likely to be multifactorial, including a dopaminergic 'overdose' and

186 y of resistant hypertension is almost always multifactorial, including obesity, older age, high dieta

187 disparity are not as obvious and are likely multifactorial, including socioeconomic and health care

188 The reasons for this are multifactorial, including the absence of a validated "ra

189 Type 1 diabetes is a multifactorial inflammatory disease in genetically susce

190 Acne is a multifactorial inflammatory skin disease with high preva

191 ypothesis of sex ratio and (2) the notion of multifactorial inheritance.

192 he soil for food and water, they translate a multifactorial input of environmental stimuli into a mul

193 tes, 1 trial found no effect of an intensive multifactorial intervention on risk for all-cause or car

194 though the reasons for treatment failure are multifactorial, intrinsic resistance to chemotherapy pla

195 ts virulence gene regulation was found to be multifactorial, involving acetate-stimulated transcripti

196 protective response mediated by c-di-GMP is multifactorial, involving chemotactic responses, utiliza

197 The pathogenesis is multifactorial, involving genetic predisposition, epithe

198 neumonia and acute respiratory distress, are multifactorial, involving host, viral, and bacterial fac

199 Although the cause is multifactorial, it is common in severely injured patient

200 While this increased mortality risk is multifactorial, it is likely associated with older age a

201 neity, from early-onset monogenic disease to multifactorial late-onset age-related macular degenerati

202 Amyotrophic lateral sclerosis (ALS) is a multifactorial lethal motor neuron disease with no known

203 ding domain (DBD) missense mutations using a multifactorial likelihood model of cancer causality.

204 asthma morbidity among Hispanic subgroups is multifactorial, likely reflecting the effects of known (

205 These data were analysed with a multifactorial linear regression model.

206 Acute respiratory distress syndrome is a multifactorial lung injury that continues to be associat

207 ance as a useful tool to address complex and multifactorial maladies such as Alzheimer's disease (AD)

208 regulates ZnT2-mediated zinc secretion in a multifactorial manner, first by enhancing zinc accumulat

209 at muscle mitochondrial mechanisms, no doubt multifactorial, may be important in deterioration of phy

210 Our results suggest that a multifactorial mechanism leads to dacryops including chr

211 but its clinical utility is often limited by multifactorial mechanism of resistance.

212 This intrinsic multifactorial mechanism of secreted protein aging and t

213 earch performed during the last decades, the multifactorial mechanism responsible for white wine prot

214 n moved from Group 1 PAH to Group 5, unclear/multifactorial mechanism.

215 clinical events when added to comprehensive, multifactorial medical therapy in people with atheroscle

216 xpanding on previous reviews, we performed a multifactorial meta-analysis of grazer effects on SOC de

217 ) is a common congenital malformation with a multifactorial model of inheritance.

218 A multifactorial model of white matter atrophy in focal ep

219 EG-VEGF provides potential insight into the multifactorial molecular mechanism by which dexamethason

220 ADHD is highly heritable and multifactorial; multiple genes and non-inherited factors

221 seal face, and cranial sutures, to produce a multifactorial narrower age range estimation of 30-34 ye

222 AD remains incurable due to its complex and multifactorial nature and lack of effective diagnostics/

223 but it is also possible that their inherent multifactorial nature and their etiological and clinical

224 The multifactorial nature of AKI etiologies and pathophysiol

225 The multifactorial nature of Alzheimer's disease calls for t

226 d progress in these areas is the complex and multifactorial nature of epilepsy, and its heterogeneity

227 of individual surface protein genes and the multifactorial nature of GAS-host interactions.

228 Given the multifactorial nature of pain in patients with ALS, diff

229 Because of the multifactorial nature of this neurodegenerative disorder

230 Considering the disease's multifactorial nature, modulation of multiple targets mi

231 NAs that target genes in all pathways of the multifactorial neovascularization process.

232 Autism is a multifactorial neurodevelopmental disorder affecting mor

233 N) and related eating disorders are complex, multifactorial neuropsychiatric conditions with likely r

234 Glaucoma is a multifactorial optic neuropathy characterized by retinal

235 Many psychiatric diseases stem from a multifactorial origin, thus conventional drug targeting

236 We describe the multifactorial origins of catalysis by the twister riboz

237 on in patients with Cushing's syndrome has a multifactorial pathogenesis and contributes to the incre

238 The multifactorial pathogenesis leading to dilated cardiomyo

239 ce elements might play a role in the complex multifactorial pathogenesis of age-related macular degen

240 ieving symptoms associated with the complex, multifactorial pathogenesis of CIU/CSU.

241 link between AAV integration events and the multifactorial pathogenesis of HCC.

242 a of inflammation, the B abortus model shows multifactorial pathogenesis of inflammatory anemia inclu

243 Congenital heart disease (CHD) has a multifactorial pathogenesis, but a genetic contribution

244 tients receiving this medication indicates a multifactorial pathogenesis.

245 universal cutaneous disease characterized by multifactorial pathogenic processes.

246 Alzheimer disease is a multifactorial pathology and the development of new mult

247 Traumatic brain injury (TBI) is a multifactorial pathology with great interindividual vari

248 These anomalies exhibit a multifactorial pattern of inheritance, with genetic and

249 bserved and potential associations among the multifactorial perpetrators of infectious metastasis and

250 Microbial virulence is a complex and often multifactorial phenotype, intricately linked to a pathog

251 hampered by small samples and highly complex multifactorial phenotypes, hindering investigations of t

252 Use of multifactorial preventive interventions for patients at

253 symptom in men, but rather a component of a multifactorial problem that may include other lower urin

254 We propose that multidrug resistance is a multifactorial process and that mouse models are useful

255 Cardiac allograft vasculopathy is a multifactorial process in which the immune system is the

256 Tfh cell differentiation is a multistage, multifactorial process involving B cell lymphoma 6 (Bcl6

257 ter aortic valve replacement thrombosis is a multifactorial process involving foreign materials, pati

258 neumococcal phase variation is a complex and multifactorial process leading to strain-specific pathog

259 WPW patients that underwent the multifactorial process of ablation had a lower mortality

260 Aging is a multifactorial process that includes the lifelong accumu

261 s of influenza A virus (IAV) infections is a multifactorial process that includes the replication cap

262 Allergic sensitization is a multifactorial process that is not only influenced by th

263 cquired resistance may also be a dynamic and multifactorial process that may necessitate the use of t

264 Sarcopenia is a complex multifactorial process, some of which involves fat infil

265 genesis of transplant vasculopathy (TV) is a multifactorial process.

266 Epigenetic gene regulation relies upon multifactorial processes that regulate multiple gene and

267 Pentraxin-3 (PTX3) is a multifactorial protein involved in immunity and inflamma

268 A large multifactorial PTR-MS data set is investigated that incl

269 Of the patients studied, 31% had multifactorial pulmonary hypertension.

270 The basis for such diverse pathologies is multifactorial, ranging from parasite phylogeny to host

271 Although the origin of fibroblasts is multifactorial, recent data implicate endothelial-to-mes

272 This finding is probably multifactorial, reflecting a combination of patient, cli

273 genes encoding cargo proteins and requires a multifactorial regulatory network to ensure appropriate

274 The pathophysiology behind these effects is multifactorial, relying on anatomic and cellular changes

275 inal responses, we constructed a multiscale, multifactorial response network (MMRN) of immunity in he

276 Multifactorial risk factors contributing to neurodevelop

277 In the setting of multifactorial risk reduction with statins and other lip

278 Our results suggest a multifactorial role of RASSF1A in suppression of liver c

279 We developed and validated a parsimonious multifactorial score for the prediction of work disabili

280 Herein we describe a comprehensive and multifactorial screening strategy to eliminate undesirab

281 oteins to assess binding site degeneracy and multifactorial splicing regulation.

282 ful resource to study plant responses during multifactorial stress and allow identifying metabolic pr

283 uld be a valuable approach for running large multifactorial studies to assess bioconcentration of the

284 velopmental functions - pilus biogenesis and multifactorial swarming motility - while shaping distinc

285 Cancer cachexia is a multifactorial syndrome characterized by body weight los

286 sation does not explain all features of this multifactorial syndrome, experimental agents that lower

287 re involved in the induction of this complex multifactorial syndrome, with the parasitic mite Varroa

288 A multifactorial [temperature (40, 50 and 60 degrees C), h

289 While this phenomenon is multifactorial, the ability of the matrix to reduce anti

290 The pathogenesis of EGPA is multifactorial: the disease can be triggered by exposure

291 While this rise is likely multifactorial, there has been scarce consideration of t

292 re than one etiologic mechanism, requiring a multifactorial treatment approach.

293 orm or tethered to a substrate, it will have multifactorial uses as a bioactive peptide by itself or

294 The etiology of the disease is multifactorial, whereas recurrent attacks of acute pancr

295 However, psychiatric disorders are highly multifactorial with a wide diversity of risk factors spr

296 earch suggests that the etiology of nsCPO is multifactorial, with a clear genetic component.

297 ophysiological mechanisms underlying ALS are multifactorial, with a complex interaction between genet

298 Human NTDs are multifactorial, with contributions from both genetic and

299 epidemiology of the disorder is complex and multifactorial, with genetic, biological, and biomechani

300 The etiology of nonadherence is multifactorial, with the strongest risk factors includin