ライフサイエンスコーパス: multilocus

1 s) provide a rapid and inexpensive source of multilocus allele frequency data for making genomically

2 ations and applied long-range haplotype- and multilocus allelic differentiation-based methods to dete

3 Here we report a multilocus analysis of nucleotide polymorphism and LD in

4 Exploratory linear mixed-effects multilocus analysis suggested that other functional vari

5 We also performed multilocus analysis, using aggregated scores of nsSNPs a

6 In contrast to standard methodology for multilocus analysis, which has focused on the dimension

7 Multilocus and whole-genome sequence analyses are becomi

8 We developed the Multilocus ANTIgenic Simulator (MANTIS) software package

9 Multilocus architecture is ancestral and maintained acro

10 We applied TREAT as a multilocus association test on >20 000 genes/regions in

11 on the dimension reduction of the data, our multilocus association-clustering test profits from the

12 aintenance of extensive polymorphism through multilocus balancing selection in a heterogeneous enviro

13 of DNA sequencing continues to fall that our multilocus barcoding approach will eclipse existing sing

14 e, we could correctly identify species using multilocus barcoding method.

15 Multilocus Bayesian mixed linear models identified 2998

16 onstruction of species-rich phylogenies from multilocus--but often incomplete--sequence data sets.

17 ilization assurance (Baker's contention) and multilocus coadaptation (Allard's argument) are two dist

18 Multilocus coalescence analyses suggested that F. albici

19 ng of ancestral recombination graphs under a multilocus coalescent model.

20 Here, we infer multilocus coalescent trees from >1000 nuclear single-nu

21 Critically, the multilocus composite score revealed that those with a gr

22 th a greater number of these genotypes per a multilocus composite, show less responsivity of reward r

23 Here we use multilocus data and ecological niche models (ENMs) to te

24 c studies based on single or, more commonly, multilocus data sets have helped resolve the placement o

25 because they can accommodate coalescence and multilocus data sets.

26 make an efficient use of information in the multilocus data.

27 A multilocus dataset was analyzed using maximum likelihood

28 Here, we analyze multilocus datasets of diverse arthropod communities, to

29 ishes and designed a three-step pipeline for multilocus DNA barcoding.

30 Multilocus DNA sequence data were used to assess the gen

31 e analyzed several sources of data including multilocus DNA sequence, climatic niche models and chrom

32 Multilocus DNA sequence-based typing revealed that the i

33 Hence multilocus epistasis makes substantial contributions to

34 Genetic analyses show that the SD is a multilocus gene complex involving two key loci--the driv

35 complex protein mixtures encoded by several multilocus gene families that function synergistically t

36 a novel Francisella species via 16S rRNA and multilocus gene sequence analysis.

37 rganisms can currently be identified only by multilocus gene sequence analysis.

38 Multilocus gene sequencing helped define clonal populati

39 The results suggest that the multilocus genetic composite is a more sensitive index o

40 ve effect of the 6 NOS1AP SNPs by means of a multilocus genetic risk score (GRS(NOS1AP)) uncovered a

41 We hypothesised that a multilocus genetic risk score could refine CHD predictio

42 A multilocus genetic risk score for BMI (GRS-BMI), calcula

43 We assessed genetic risk with a multilocus genetic risk score.

44 leotide polymorphisms (SNPs) and constructed multilocus genetic risk scores (GRSs) for each individua

45 We evaluated whether including multilocus genetic risk scores (GRSs) into the Framingha

46 A multilocus genetic score reflecting genetic variability

47 Multilocus genome-wide association studies (GWAS) have b

48 Modeling of phenotypes for multilocus genotype classes in the epistatic networks is

49 series of methods in population genetics use multilocus genotype data to assign individuals membershi

50 have been proposed to perform clustering on multilocus genotype data.

51 In these models, the multilocus genotype is mapped to fitness in two steps.

52 passing 5'UTR-Intron 1 of LRRTM3 that formed multilocus genotypes (MLG) with suggestive global associ

53 These clustered into 136 multilocus genotypes (MLGs), with 32% of MLGs recovered

54 Multilocus genotypes from 7 microsatellite loci suggeste

55 le in a relatedness analysis are a sample of multilocus genotypes from which both allele frequencies

56 ention to frequencies of locally most common multilocus genotypes in Floridian populations of the Man

57 Microsatellite multilocus genotypes of the pre-logging populations were

58 significantly correlated with the number of multilocus genotypes present.

59 ic reconstruction were applied to individual multilocus genotypes to infer the genetic structure and

60 s of clonal evolutionary relationships among multilocus genotypes with the eBURST algorithm and analy

61 al discriminative/predictive capability of 4 multilocus GRSs for incident CHD among subjects of Europ

62 e regression with empirical Bayes to perform multilocus GWAS under polygenic background control.

63 A frequently applied metric, multilocus heterozygosity (MLH), and an F estimator base

64 se familial biparental hydatidiform mole and multilocus imprinting disturbance, respectively.

65 5 in five mothers of individuals affected by multilocus imprinting disturbance.

66 od of this phenomenon (referred to herein as multilocus inherited neoplasia alleles syndrome [MINAS])

67 cores weighted by the T2D log odds ratio and multilocus kernel tests also indicated a significant rel

68 In using multilocus linkage disequilibrium (LD) to infer recombin

69 The absence of multilocus linkage disequilibrium and the high proportio

70 We concluded that LOS is a multilocus LOI syndrome, as is BWS.

71 digree of a sample of individuals from their multilocus marker genotypes.

72 p and parentage among individuals from their multilocus marker genotypes.

73 ratio in gametophyte plants (ramets) and in multilocus microsatellite genotypes (genets).

74 ly fixed for a single clone as determined by multilocus microsatellite genotyping.

75 Multilocus mixed model analysis confirmed the advantage

76 traits that were stable over 2 years using a multilocus mixed model as a general method for mapping c

77 ed by implementing rank transformation and a multilocus mixed model to map alleles controlling 20 ele

78 chromosome were included simultaneously in a multilocus model and least angle regression was used to

79 However, implementation of multilocus model in GWAS is still difficult.

80 The selected SNPs in multilocus model were further detected for their associa

81 ich was suggested by recent studies based on multilocus molecular markers.

82 arge population samples and both plastid and multilocus nuclear genotypes resolved the relationships

83 olecular Inc., Des Plaines, IL) incorporates multilocus PCR and electrospray ionization-mass spectrom

84 Multilocus phylogenetic analyses showed that MRE form a

85 f Schizophyllum from the United States using multilocus phylogenetic analysis and their in vitro susc

86 Based on multilocus phylogenetic analysis, YSLV6 shows a close ev

87 A multilocus phylogenetic study was carried out to assess

88 Despite progress based on multilocus, phylogenetic studies of the palms (order Are

89 these issues, we first provide a snapshot of multilocus phylogeographic studies across the Carpentari

90 ious theory suggests that the conditions for multilocus polymorphism are restrictive.

91 ective longitudinal study, we investigated a multilocus profile of genetic risk derived from publishe

92 , modeling epistatic relationships and using multilocus profiles.

93 for quantitative traits utilizing a range of multilocus quantitative genetic models and gene frequenc

94 andom-SNP-effect mixed linear model and fast multilocus random-SNP-effect EMMA methods had almost equ

95 pLARmEB, multilocus random-SNP-effect mixed linear model and fast

96 explore a more general class of models with multilocus seasonally fluctuating selection in diploids.

97 cterization of a subset of horse isolates by multilocus sequence analysis (MLSA) and 16S rRNA gene se

98 Although multilocus sequence analysis (MLSA) is considered the go

99 Multilocus sequence analysis (MLSA) was used to clarify

100 C. difficile genotypes were determined by multilocus sequence analysis and PCR ribotyping; sequenc

101 Multilocus sequence analysis confirmed that the 21 NT H.

102 osis of Nocardia species was performed using multilocus sequence analysis of gyrase B of the beta sub

103 ized morphologically and molecularly using a multilocus sequence analysis that included the internal

104 o classify isolates into distinct species, a multilocus sequence analysis using rpoB and internal tra

105 Multilocus sequence data collected from a subset of 128

106 3 international clonal complexes, belongs to multilocus sequence type (MLST) 10, and is most closely

107 and repetitive extragenic palindromic-PCR), multilocus sequence type (MLST) analysis, and WGS on 148

108 m 0.02 to 4.865 mug/ml and correlated with a multilocus sequence type (MLST) clonal complex associate

109 States and Canada between 1992 and 2013 were multilocus sequence type (ST) 1.

110 Streptococcus agalactiae strain representing multilocus sequence type (ST) 17, isolated from a coloni

111 umoniae, most notably isolates classified as multilocus sequence type (ST) 258, have emerged as an im

112 al and spatial diverse S. aureus isolates of multilocus sequence type (ST) 8 to reconstruct the molec

113 moniae is primarily associated with a single multilocus sequence type (ST), ST258, and its related va

114 21 genetic backgrounds, as determined by the multilocus sequence type (ST).

115 of the E coli genome showed it to belong to multilocus sequence type 131 (ST131).

116 All MRSA belonged to multilocus sequence type 239 (ST 239).

117 Klebsiella pneumoniae strains classified as multilocus sequence type 258 (ST258) are among the most

118 , including the epidemic KPC-producing clone multilocus sequence type 258 (ST258).

119 var Typhimurium (45% [116/258] of which were multilocus sequence type 313).

120 nella enterica serovar Typhimurium strain of multilocus sequence type 313, the predominant genotype c

121 Sequencing of a multilocus sequence type 95 (ST95) serogroup O1 strain p

122 he property's groundwater supply matched the multilocus sequence type of the clinical isolates.

123 Genotype (multilocus sequence type) and fluoroquinolone susceptibi

124 arches) were used to determine stx subtypes, multilocus sequence types (15 loci), and the presence of

125 of strains representing different serotypes, multilocus sequence types (MLST), and sites of clinical

126 s performed to produce a phylogeny, identify multilocus sequence types (MLST), multiantigen sequence

127 erformed to produce a phylogeny and identify multilocus sequence types (MLST), N. gonorrhoeae multian

128 n addition, the correspondence between PFGE, multilocus sequence types (MLSTs), and rtxA gene sequenc

129 e of 28 E. faecalis isolates representing 24 multilocus sequence types (MLSTs), including human comme

130 5 USA500 isolates yielded 3 spa types and 2 multilocus sequence types (MLSTs).

131 We screened the collection for multilocus sequence types (STs) and for host specific re

132 rkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated f

133 Previously, Bayesian clustering of 437 multilocus sequence types (STs) in the international dat

134 h chronic melioidosis demonstrated identical multilocus sequence types (STs).

135 ins representing epidemiologically important multilocus sequence types ST131, ST73, and ST95 and non-

136 ote, only four isolates (7%) of the 56 whose multilocus sequence types were determined were found to

137 ally, the software identifies a cluster of 9 multilocus sequence types with abnormally high 'virulenc

138 metronidazole resistance were similar in all multilocus sequence types.

139 did whole genome sequencing and core genome multilocus sequence typing (1546 loci) on serogroup W di

140 strategies were used to generate core genome multilocus sequence typing (cgMLST) data.

141 we proposed the development of a core genome multilocus sequence typing (cgMLST) scheme for M. gallis

142 es and in three European countries presented multilocus sequence typing (MLST) alleles, sequence type

143 lecular characterization was performed using multilocus sequence typing (MLST) alongside traditional

144 he specificity and sensitivity inferred from multilocus sequence typing (MLST) and genome-wide SNP-ba

145 Multilocus sequence typing (MLST) and multi-virulence-lo

146 he same patient were molecularly typed using multilocus sequence typing (MLST) and multispacer sequen

147 MRSA isolates were further genotyped using multilocus sequence typing (MLST) and pulsed-field gel e

148 virulence-associated genes were analyzed by multilocus sequence typing (MLST) and sequence analysis

149 Characterization of PVL-MSSA isolates by multilocus sequence typing (MLST) and spa typing in this

150 The data for these isolates included multilocus sequence typing (MLST) and staphylococcal pro

151 genotyping approaches: gyrB gene sequencing, multilocus sequence typing (MLST) and whole genome clust

152 discriminatory power was compared to that of multilocus sequence typing (MLST) and whole-genome optic

153 terizes B. hampsonii using a newly developed multilocus sequence typing (MLST) approach and elucidate

154 In this study, we have used a multilocus sequence typing (MLST) approach employing the

155 d no strong correlation between CPS type and multilocus sequence typing (MLST) cluster, with the rema

156 Although multilocus sequence typing (MLST) currently represents t

157 Multilocus sequence typing (MLST) data demonstrated that

158 nalysis of the population structure based on multilocus sequence typing (MLST) data derived from the

159 A multilocus sequence typing (MLST) database for V. paraha

160 Multilocus sequence typing (MLST) demonstrated 21 known

161 Comparison between WGS and multilocus sequence typing (MLST) identified major discr

162 he 16S-23S rRNA intergenic spacer region and multilocus sequence typing (MLST) indicated a predominan

163 Multilocus sequence typing (MLST) is the gold standard g

164 capsular biosynthetic loci, and 8 targeting multilocus sequence typing (MLST) loci were employed for

165 We performed multilocus sequence typing (MLST) on all isolates and se

166 Multilocus sequence typing (MLST) revealed 24 sequence t

167 pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST) revealed a high level

168 A multilocus sequence typing (MLST) scheme for M. pneumoni

169 of the genetic diversity of this pathogen, a multilocus sequence typing (MLST) scheme was developed a

170 In this study, we introduce a multilocus sequence typing (MLST) scheme, comprised of s

171 e identified and used to develop an expanded multilocus sequence typing (MLST) scheme.

172 re of this genus, we developed a genus-level multilocus sequence typing (MLST) scheme.

173 d 167 isolates into 39 groups and subsequent multilocus sequence typing (MLST) separated a subset of

174 hypothesis by performing the first extensive multilocus sequence typing (MLST) survey of plumbing dra

175 clades are assigned to ST131 by the Achtman multilocus sequence typing (MLST) system and a screening

176 pulsed-field gel electrophoresis (PFGE), and multilocus sequence typing (MLST) to characterize them a

177 Here, we used multilocus sequence typing (MLST) to compare the molecul

178 Multilocus sequence typing (MLST) was able to accurately

179 Nested multilocus sequence typing (MLST) was employed for case

180 pulsed-field gel electrophoresis (PFGE), and multilocus sequence typing (MLST) were performed.

181 repetitive-sequence-based PCR (rep-PCR) and multilocus sequence typing (MLST) were performed.

182 ncluded PCR detection of ply and psaA genes, multilocus sequence typing (MLST), 16S rRNA gene sequenc

183 ing pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), and clustered regular

184 notyped by pulsed field gel electrophoresis, multilocus sequence typing (MLST), and molecular capsule

185 riable number tandem repeat analysis (MLVA), multilocus sequence typing (MLST), and pertactin gene (p

186 ing pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), and serotyping.

187 FGE), Staphylococcus protein A (spa) typing, multilocus sequence typing (MLST), and staphylococcal ca

188 by pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), and staphylococcal pr

189 The isolates underwent multilocus sequence typing (MLST), as well as assays for

190 of sequence-based typing approaches, such as multilocus sequence typing (MLST), by substantially incr

191 Sequence-based typing (SBT), analogous to multilocus sequence typing (MLST), is the current "gold

192 during 2002 to 2008 in Great Britain, using multilocus sequence typing (MLST), pulsed-field gel elec

193 lution antimicrobial susceptibility testing, multilocus sequence typing (MLST), spa typing, SCCmec ty

194 2016 with the isolates confirmed as ST398 by multilocus sequence typing (MLST), which prompted retros

195 onsistent with genomotypes assigned by using multilocus sequence typing (MLST).

196 Selected isolates were subjected to multilocus sequence typing (MLST).

197 in China, Sweden, and Egypt were subtyped by multilocus sequence typing (MLST).

198 y repetitive sequence-based PCR (repPCR) and multilocus sequence typing (MLST).

199 ism analysis (RFLP), PCR fingerprinting, and multilocus sequence typing (MLST).

200 by using polymerase chain reaction (PCR) and multilocus sequence typing (MLST).

201 solates causing meningitis were genotyped by multilocus sequence typing (MLST).

202 raditional method of amplicon sequencing for multilocus sequence typing (MLST).

203 Selected strains were evaluated by multilocus sequence typing (MLST).

204 ups within clonal groups defined by standard multilocus sequence typing (MLST).

205 sive) from 2011 to 2014 was characterized by multilocus sequence typing (MLST).

206 Select isolates then underwent multilocus sequence typing (MLST).

207 pulsed-field gel electrophoresis (PFGE), and multilocus sequence typing (MLST).

208 ribotyping, genome restriction mapping, and multilocus sequence typing (MLST).

209 genomic clades of Bp, largely congruent with multilocus sequence typing (MLST).

210 owing: conventional, extended, and ribosomal multilocus sequence typing (MLST, eMLST, and rMLST); ant

211 Ribosomal multilocus sequence typing (rMLST) using ribosomal prote

212 lectrophoresis (PFGE); however, conventional multilocus sequence typing (targeting 6 conserved loci)

213 ltiple different ancestral origins (based on multilocus sequence typing [MLST] analysis), and did not

214 icd allele 96 and gyrB allele 87, two of the multilocus sequence typing alleles that define ST648; an

215 restriction fragment length polymorphism and multilocus sequence typing analysis.

216 We applied multilocus sequence typing and a microarray for detectio

217 valuation of genotypic (gene comparisons and multilocus sequence typing and analysis), genomic (dDDH,

218 pes (sequence types [ST]) were defined using multilocus sequence typing and assigned to a clonal comp

219 borrelial DNA in ticks were characterized by multilocus sequence typing and by sequencing five other

220 BLEC by pulsed-field gel electrophoresis and multilocus sequence typing and identified their blaESBL

221 cell lymphoma, which was identified both by multilocus sequence typing and matrix-assisted laser des

222 Isolates underwent multilocus sequence typing and PCR sequencing of the wzi

223 latedness of the isolates was assessed using multilocus sequence typing and phylogenetic analyses.

224 sely related porA sequences was confirmed by multilocus sequence typing and pulsed-field gel electrop

225 Whole-genome multilocus sequence typing and single nucleotide polymor

226 DNA uptake sequence signatures, metagenomic multilocus sequence typing and strain-specific marker ge

227 Multilocus sequence typing and whole-genome sequence com

228 We show that emm typing and multilocus sequence typing can be achieved rapidly and e

229 Serotype and multilocus sequence typing data for 426 pneumococci date

230 ce types and showed improved congruence with multilocus sequence typing data.

231 Multilocus sequence typing effectively distinguished 82

232 We compared Xpert C. difficile/Epi to multilocus sequence typing for identification of C. diff

233 Although the sequences of each of the seven multilocus sequence typing genes were identical in the t

234 ST17) were identified for the first time by multilocus sequence typing in an area where bathing had

235 Multilocus sequence typing indicates that C. difficile s

236 hole-genome sequencing was used to determine multilocus sequence typing information and identify gene

237 A multilocus sequence typing method was also established f

238 Multilocus sequence typing of Borrelia hermsii isolates

239 analysis of PCR amplified16S rRNA genes, and multilocus sequence typing of three housekeeping genes c

240 s were serotyped; susceptibility testing and multilocus sequence typing on Salmonella enterica serova

241 s of clinical M. abscessus isolates utilized multilocus sequence typing or pulsed-field gel electroph

242 s pulsed-field gel electrophoresis (PFGE) or multilocus sequence typing profiles to that of known epi

243 We recently described a multilocus sequence typing scheme (MLST) for P. acnes ba

244 We have created the first multilocus sequence typing scheme (MLST) for P. larvae,

245 ity within the species based on the existing multilocus sequence typing scheme.

246 ation showed that the arcC genes used in the multilocus sequence typing schemes of these two species

247 smetic injections and the first report using multilocus sequence typing sequence data for determining

248 e development and evaluation of an effective multilocus sequence typing strategy for M. xenopi.

249 Multilocus sequence typing was successfully completed on

250 In this study, multilocus sequence typing was used to investigate genot

251 electrophoresis) patterns and the same MLST (multilocus sequence typing) sequence type (ST-1068) rega

252 action, pulse-field gel electrophoresis, and multilocus sequence typing).

253 chain reaction, phylogeny was assigned using multilocus sequence typing, and clonal relatedness was e

254 ase genes, pulsed-field gel electrophoresis, multilocus sequence typing, and plasmid analysis were pe

255 Using serotyping, multilocus sequence typing, and whole-genome sequencing

256 Whole-genome sequencing was used to perform multilocus sequence typing, capsular typing, and identif

257 ere characterized by susceptibility testing, multilocus sequence typing, DiversiLab, and plasmid anal

258 Relatedness was assessed by multilocus sequence typing, fitness was evaluated by gro

259 brial adhesin gene: H subclone assignments), multilocus sequence typing, gyrA and parC sequence (fluo

260 6S-23S ribosomal RNA intergenic spacer type, multilocus sequence typing, or both.

261 iers, and blood cultures were analyzed using multilocus sequence typing, phylotyping, ESBL genes, pla

262 ics of the strains, which were determined by multilocus sequence typing, sap typing, and the presence

263 Using multilocus sequence typing, we investigated the genetic

264 mining of this enormous data set to create a multilocus sequence typing-based scheme that can identif

265 Meningococcal CCs were assessed by multilocus sequence typing.

266 pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing.

267 iverse and can be classified by serotype and multilocus sequence typing.

268 C. trachomatis samples were typed using multilocus sequence typing.

269 s from the same counties were compared using multilocus sequence typing.

270 to 2011, we identified 85 sequence types by multilocus sequence typing.

271 rsity of the isolates was investigated using multilocus sequence typing.

272 dom (approximately 600,000 people) underwent multilocus sequence typing.

273 staphylococcal chromosomal cassette mec and multilocus sequence typing.

274 cile infection (CDI) fecal samples underwent multilocus sequence typing.

275 nfirmed by a number of biochemical tests and multilocus sequence typing.

276 elineated into 12 sequence types (STs) using multilocus sequence typing.

277 ptococcus pneumoniae, and isolates underwent multilocus sequence typing.

278 n, partial sequencing of the groEL gene, and multilocus sequencing of 7 housekeeping genes confirmed

279 lates belonging to the ST10, ST23, and ST169 multilocus sequencing types.

280 ive whole-genome sequencing with core genome multilocus sequencing typing (cgMLST) analysis for real-

281 Using a multilocus short-sequence-repeat technique, we found 15

282 A time-calibrated multilocus species tree revealed a pattern of Miocene an

283 erinary relevance within Fusarium Six of the multilocus STs within the FSSC (3+4-eee, 1-b, 12-a, 12-b

284 To answer this question, we developed a multilocus typing assay based on high-throughput sequenc

285 Multilocus variable number of tandem repeats analysis (M

286 Pulsed-field gel electrophoresis (PFGE) and multilocus variable number tandem repeat analysis (MLVA)

287 ded pulsed-field gel electrophoresis (PFGE), multilocus variable number tandem repeat analysis (MLVA)

288 e-nucleotide polymorphism (SNP) analysis, by multilocus variable number tandem repeats analysis, and

289 enetic clusters that were directly linked to multilocus variable-number tandem repeat analysis (MLVA)

290 aphylococcal protein A (spa) typing and with multilocus variable-number tandem repeat analysis (MLVA)

291 WGS also correlated well with multilocus variable-number tandem repeat analysis (MLVA)

292 inly performed through PCR-based methods and multilocus variable-number tandem-repeat (VNTR) analysis

293 his study, we evaluated a recently developed multilocus variable-number tandem-repeat (VNTR) analysis

294 f strains revealed cocirculation of multiple multilocus variable-number tandem-repeat analysis (MLVA)

295 genome sequencing and two PCR-based methods, multilocus variable-number tandem-repeat analysis (MLVA)

296 pes 1 [60%] and 2 [40%]) and seven different multilocus variable-number tandem-repeat analysis (MLVA)

297 ed using the major adhesion protein (P1) and multilocus variable-number tandem-repeat analysis (MLVA)

298 No study to date has compared multilocus variable-number tandem-repeat analysis (MLVA)

299 In this study, multilocus variable-number tandem-repeat analysis (MLVA)

300 To address these issues, we developed a multilocus Wright-Fisher model of HIV dynamics with sele