ライフサイエンスコーパス: multimolecular

1 interactions allow MuSK not only to induce a multimolecular AChR-containing complex, but also to loca

2 ce that FcalphaR-mediated signals modulate a multimolecular adaptor protein complex containing Grb2,

3 ates to cytoplasmic stress granules that are multimolecular aggregates of stalled translation initiat

4 y in conveying explicit signals across large multimolecular assemblies and distances to specify cellu

5 n water to form different kinds of nanoscale multimolecular assemblies ranging from simple micelles a

6 KAP) sequences that can act as scaffolds for multimolecular assemblies that facilitate and limit cAMP

7 l molecules are designed to come together in multimolecular assemblies, such as in coordination cages

8 ociates with p300, suggesting a mechanism of multimolecular assembly at the +6.1 kb site.

9 ERK1/2 co-immunoprecipitated with Akt in a multimolecular assembly of signaling molecules, containi

10 insen cage" whose primary role is to prevent multimolecular association during folding.

11 involves the formation of a ligand-dependent multimolecular association of receptor chains (alpha and

12 that the difference is caused by reversible multimolecular association while folding in solution, an

13 By applying pulsed multimolecular beam experiments and in situ infrared ref

14 d that RyR2 and CASQ2 interact as parts of a multimolecular Ca(2+)-signaling complex; however, direct

15 Multimolecular caps appeared within minutes of B7-DC XAb

16 pathway initiation complexes are composed of multimolecular carbohydrate recognition subcomponents an

17 about the rules that guide the formation of multimolecular chromatin-bound complexes have helped to

18 lexes on the surface of human fibroblasts in multimolecular clusters unassociated with coated pits, a

19 ized red blood cells support the assembly of multimolecular coagulation complexes.

20 and repair factors, could assemble to form a multimolecular complex ("mutasome") at the site of DNA l

21 ProMMP-2 activation requires multimolecular complex assembly involving proMMP-2, memb

22 crophage cytosol activates a host-protective multimolecular complex called the inflammasome to releas

23 ata indicate that a significant portion of a multimolecular complex containing Cbl, SLP-76, Shc, and

24 ting expression of PTPmu and by organizing a multimolecular complex containing PKCbetaII, RACK1, PTPm

25 CT molecules in a temporal fashion to form a multimolecular complex during the early stages of endoth

26 ssium conductance and spatial buffering, and multimolecular complex dynamics, and indicate both estab

27 cognate interactions by, e.g. affecting TCR-multimolecular complex formation and antigen binding aff

28 The activation process requires multimolecular complex formation involving pro-MMP-2, me

29 eginnings and the AR increase is part of the multimolecular complex including downstream effector pro

30 ed that the presence of a specific pRb2/p130 multimolecular complex on the ER-alpha promoter strongly

31 kinase activity, (iv) activation of Sos in a multimolecular complex that contains p46Shc, and p52Shc,

32 The hemidesmosome is a multimolecular complex that integrates the extracellular

33 e dystrophin glycoprotein complex (DGC) is a multimolecular complex that links the extracellular matr

34 CAS is thus part of a multimolecular complex that, along with other cadherin-b

35 nt phosphorylation of multiple proteins in a multimolecular complex with attendant modulation of thei

36 Moreover, we demonstrate that TLR9 forms a multimolecular complex with gp96 and CNPY3, and the bind

37 binds to HSP90 and disrupts the Raf-1-HSP90 multimolecular complex, leading to destabilization of Ra

38 thway in which five proteins assemble into a multimolecular complex, the membrane attack complex (MAC

39 antigenic sites and neighboring Ags within a multimolecular complex.

40 on of a connexin domain when integrated in a multimolecular complex.

41 ity is analogous to cooperativity in another multimolecular complex: hemoglobin.

42 r CD8(+) cells named self-immune stimulatory multimolecular complexes (ISMMC).

43 UFH, LMWH, 16-, 8-, 6-mer), (2) formation of multimolecular complexes (UFH, 16-, 8-mer), and (3) ener

44 ore mechanisms governing dynamic assembly of multimolecular complexes and their role in shaping cellu

45 ndothelium; 2) whether they are organized in multimolecular complexes as in neurons; and 3) whether t

46 We have previously shown that PF4:H multimolecular complexes assemble through electrostatic

47 or that they function as mutually exclusive multimolecular complexes by providing direct support for

48 These findings suggest that pRb2/p130-multimolecular complexes can be key elements in the regu

49 They are enriched in multimolecular complexes composed of voltage-gated Nav a

50 s in neurons; and 3) whether the endothelial multimolecular complexes differ from their neuronal coun

51 In this report, we investigated the multimolecular complexes formed following anti-Ig stimul

52 oth macroscopic visible aggregates and small multimolecular complexes in solution are capable of indu

53 Current concepts favour their assembly into multimolecular complexes in the plasma membrane in respo

54 of ER-alpha chromatin structure by pRb2/p130 multimolecular complexes may influence its susceptibilit

55 imulations show that cooperative assembly of multimolecular complexes nucleated by activated receptor

56 openia is initiated by and directed to large multimolecular complexes of platelet factor 4 (PF4) and

57 ed by platelet-activating antibodies against multimolecular complexes of platelet factor 4 and hepari

58 ciated proteins could direct the assembly of multimolecular complexes on leukocyte microvilli.

59 facilitate signal transduction by preforming multimolecular complexes that can be rapidly activated b

60 ively charged compounds through formation of multimolecular complexes that lead to dendritic cell act

61 e presence of both BIG1 and KANK1 in dynamic multimolecular complexes that maintain Golgi/MTOC orient

62 etraspanins are membrane molecules that form multimolecular complexes with a broad array of molecules

63 Many autoantigens are components of multimolecular complexes, and some of the other componen

64 gesting that it may be part of two different multimolecular complexes.

65 or protein, and that mediate the assembly of multimolecular complexes.

66 lyses, showed that FoxP3 existed in distinct multimolecular complexes.

67 and are relevant to studying a wide range of multimolecular complexes.

68 ng molecules that coordinate the assembly of multimolecular complexes.

69 It is also not clear how multimolecular DNA toroids and rods interconvert in solu

70 appropriate when the overall compositions of multimolecular ensembles are of greater importance than

71 the transmitter-release mechanism exist as a multimolecular entity and that this interaction has func

72 ide that spontaneously self-assembles into a multimolecular fibrillar architecture to drive the coass

73 Several new pairs were applied in a multimolecular FRET based sensor for detecting activatio

74 Multimolecular G-quadruplex formation is influenced by r

75 Because multimolecular G-quadruplexes are enhanced by repeat len

76 s study we show that Ca(v)beta subunits form multimolecular homo- and heterooligomeric complexes in h

77 the elements in the basement membrane via a multimolecular junction called the hemidesmosome.

78 Recent work on multimolecular lipid structures suggests a critical role

79 gher eukaryotes; they function together as a multimolecular machine that assembles quasinative CCT-ge

80 on is the result of the integrated action of multimolecular machineries.

81 We propose that PON is one component of a multimolecular machinery that localizes Numb by respondi

82 Podosomes are multimolecular mechanosensory assemblies that coordinate

83 on target cells to mediate effects; (ii) the multimolecular membrane attack complex generated from th

84 to facilitate the organization of functional multimolecular membrane complexes.

85 The dystrophin complex is a multimolecular membrane-associated protein complex whose

86 ly, organization, and efficient operation of multimolecular myosin phosphatase complexes that include

87 current spikes corresponding to detection of multimolecular packets secreted by exocytosis.

88 GGCCCC)n RNA forms extremely stable uni- and multimolecular parallel G-quadruplex structures (up to 9

89 n (Ag) processing requires the action of the multimolecular peptide-loading complex within the endopl

90 Multimolecular phenotyping demonstrates that the molecul

91 ntracellular "molecular sensor" that forms a multimolecular platform, the NLRP3 inflammasome, which l

92 ces the formation of focal adhesion plaques, multimolecular platforms for second-phase insulin releas

93 duction, silence transcription, and regulate multimolecular protein assembly.

94 ed with folding nascent proteins, assembling multimolecular protein complexes and degrading cytosolic

95 Multimolecular protein complexes are important for many

96 he activity of interleukin-1 is regulated by multimolecular protein complexes called inflammasomes.

97 aracterize the large, dynamic, heterogeneous multimolecular protein complexes formed.

98 ms leading to the activation of cytoplasmic, multimolecular protein complexes, termed "inflammasomes,

99 The formation of a multimolecular proximal signaling complex nucleated by t

100 alone is insufficient to predict whether the multimolecular racemate will or will not segregate.

101 igin of dielectric response at the molecular/multimolecular scale.

102 ediates spreading through the formation of a multimolecular signaling complex at the cell surface tha

103 thermore, we observe that murine KSR forms a multimolecular signaling complex in human embryonic kidn

104 orm of protein kinase C (eye-PKC) comprise a multimolecular signaling complex via their interaction w

105 ation because of its association with AKAP18 multimolecular signaling complexes and suggest that targ

106 ubstrate of ZAP-70 that mediates assembly of multimolecular signaling complexes at the plasma membran

107 Cytokines trigger the rapid assembly of multimolecular signaling complexes that direct the activ

108 n as a molecular scaffold in the assembly of multimolecular signaling complexes.

109 arget cells by gammadelta T cells required a multimolecular stress signature composed of EPCR and cos

110 anolamine, Salmonella enterica synthesizes a multimolecular structure that mimics the carboxysome use

111 Signalling complexes are dynamic, multimolecular structures and sites for intracellular si

112 s, 14 of which are on components of the same multimolecular T-cell receptor complex.

113 leoplasmic concentrations and/or assembly of multimolecular transcription regulatory complexes, which