ライフサイエンスコーパス: multinucleated cell

1 division without cytokinesis, resulting in a multinucleated cell.

2 rporates as many as 200 cells into one large multinucleated cell.

3 t morphologies including elongated and round multinucleated cells.

4 aa3 expression peaked prior to appearance of multinucleated cells.

5 on were found among the nuclei in individual multinucleated cells.

6 12-Cdc42 lines displayed a high frequency of multinucleated cells.

7 rs abscission and increases the incidence of multinucleated cells.

8 o undergo proper cytokinesis and resulted in multinucleated cells.

9 nd pleiotropic tendencies largely made up of multinucleated cells.

10 mononuclear preosteoclasts fuse to generate multinucleated cells.

11 n of GEFs in the morphological maturation of multinucleated cells.

12 s, resulting in the accumulation of enlarged multinucleated cells.

13 rounds of endoreduplication and resulting in multinucleated cells.

14 ved cell cycle regulators directs mitosis in multinucleated cells.

15 T in HeLa cells resulted in the formation of multinucleated cells.

16 pensable for psychosine-induced formation of multinucleated cells.

17 and Mat89Bb RNAi in HeLa cells gives rise to multinucleated cells.

18 kinesis failure, and formation of micro- and multinucleated cells.

19 ruiting the fusion of cells with preexisting multinucleated cells.

20 in the heart, resulting in the formation of multinucleated cells.

21 f cell membranes are overcome and cells form multinucleated cells.

22 uclei with decondensed DNA, and formation of multinucleated cells.

23 accumulation of supernumerary centrosomes in multinucleated cells.

24 s prolonged expression promoted formation of multinucleated cells.

25 hyperproliferation, suprabasal mitoses, and multinucleated cells.

26 tive lymphocytes fuse in lymph nodes to form multinucleated cells.

27 ced from cytokinesis and so produces bi- and multinucleated cells.

28 ormed cell walls, increased DNA content, and multinucleated cells.

29 4 or 21 days to induce formation of OCL-like multinucleated cells.

30 a transdominant-negative TXBP181 results in multinucleated cells, a phenotype consistent with a loss

31 d lysosomes within perivascular macrophages, multinucleated cells, activated microglial cells, and hy

32 uble-stranded RNA resulted in a formation of multinucleated cells and also reduced DNA replication.

33 exhibited an increase in both the number of multinucleated cells and cells with swollen flagellar po

34 These abnormalities included both multinucleated cells and enlarged cells with giant nucle

35 this study revealed the presence of abnormal multinucleated cells and increased apoptotic cells withi

36 sion of this mutant induces the formation of multinucleated cells and increases their susceptibility

37 Its failure leads to multinucleated cells and is a possible cause of tumorige

38 tartrate-resistant acid phosphatase-positive multinucleated cells and measuring the expression of ost

39 nhibition of Aurora B by hesperadin produced multinucleated cells and reduced H3S10 phosphorylation.

40 sizes of infected cells were evident: large multinucleated cells and small nondescript (presumptivel

41 Osteoclasts are multinucleated cells and the principal resorptive cells

42 phytic tissue), both TRAP-positive mono- and multinucleated cells and TRAP-negative, NSE-positive mon

43 d size, have increased numbers of nuclei per multinucleated cell, and demonstrate increased resorptio

44 lar spindles, aberrant mitosis, formation of multinucleated cells, and decreased DNA replication.

45 pletion generates supernumerary centrosomes, multinucleated cells, and multipolar spindle formation.

46 Multinucleated cells are found in diverse contexts and i

47 lonogenic outgrowth, and high percentages of multinucleated cells are found in vivo in remnants of PA

48 Multinucleated cells are important in many organisms, bu

49 Multinucleated cells are relatively resistant to classic

50 lure in mitotic exit, with the appearance of multinucleated cells as a consequence.

51 tartrate-resistant acid phosphatase-positive multinucleated cells at sites of bone erosion.

52 confirmed by immunofluorescence staining on multinucleated cells at the bone surface of inflamed mou

53 osteoclasts and suggest that osteoclast-like multinucleated cells can arise in synovial soft tissues

54 indle-shaped cells, as well as flat adherent multinucleated cells capable of spontaneous contractions

55 ure of HPCs manifested by an accumulation of multinucleated cells caused by failed abscission of the

56 l-cell fusion that resulted in generation of multinucleated cells, centrosome amplification, multipol

57 c phenotype, which includes the formation of multinucleated cells, centrosome and mitotic spindle abn

58 it had no effect on the formation of giant, multinucleated cells characteristic of mitotic catastrop

59 Giant multinucleated cells containing nuclei attached by const

60 bone resorption associated with bone-derived multinucleated cell-containing granulomatous lesions.

61 g, resulting in cell flattening, senescence, multinucleated cells, decreased S-phase progression, dim

62 increased resorption capacity compared with multinucleated cells derived from empty vector-transduce

63 Multinucleated cells expressing both TRAP and cathepsin

64 PARP-inhibitor-induced multinucleated cells fail clonogenic outgrowth, and high

65 eventual degeneration with the formation of multinucleated cells following Cx43 overexpression due t

66 bited the differentiation of osteoclast-like multinucleated cell formation in the presence of several

67 Legumain significantly inhibited OCL-like multinucleated cell formation induced by 1,25-dihydroxyv

68 ion of AXII significantly increased OCL-like multinucleated cell formation.

69 dges, micronuclei, centrosome amplification, multinucleated cells, gradual accumulation of DNA damage

70 Remarkably, multinucleated cell hybrids gave rise to mononucleated p

71 with occasional pseudonuclear inclusion and multinucleated cells in a partly myxoid matrix.

72 tartrate-resistant acid phosphatase-positive multinucleated cells in both cell types.

73 The formation of fused multinucleated cells in ganglia might be associated with

74 nesis was assessed by counting TRAP-positive multinucleated cells in PB CD14+ monocytes cultured with

75 428 and KM-H2 as well as on the formation of multinucleated cells in the mononuclear human embryonic

76 ved in epithelial cells, fibroblasts, and in multinucleated cells in the periodontium.

77 mitotic phase with the formation of abnormal multinucleated cells, indicating that this compound affe

78 rant cell plates, incomplete cell walls, and multinucleated cells, leading to severely abnormal seedl

79 opic expression of the Tg737 gene results in multinucleated cells, loss of Tg737 gene expression resu

80 ed and isolated from a human osteoclast-like multinucleated cell (MNC) cDNA library, named osteoclast

81 als, mandibles and tibiae were isolated, and multinucleated cells (MNCs) were measured.

82 Multinucleated cells (MNCs) were present in resorption l

83 cell types: mononuclear polyhedral cells and multinucleated cells (MNCs).

84 sion led to a highly significant increase of multinucleated cells, nuclear volume, and 3D telomeric a

85 he nucleus, p53 localization was analyzed in multinucleated cells obtained by polyethylene glycol-med

86 osophila larval skeletal muscles are single, multinucleated cells of different sizes that undergo tre

87 Osteoclasts are multinucleated cells of hemopoietic origin that are resp

88 tartrate-resistant acid phosphatase-positive multinucleated cells or resorption pits were observed in

89 ates that included death, fusion that formed multinucleated cells, or another round of mitosis with n

90 -zoster virus (VZV) characteristically forms multinucleated cells, or syncytia, during the infection

91 re characterized by an increased presence of multinucleated cells, osteoclasts, and cementicles.

92 was equally distributed among the nuclei of multinucleated cells regardless of the stage of the cell

93 The presence of binucleated and multinucleated cells, reminiscent of large lymphocytes w

94 Cs to overexpress NS decreases senescent and multinucleated cells, restores morphology, and antagoniz

95 Other subcellular effects observed included multinucleated cells seen after RNAi to either pgant2 or

96 pX-1 cells exhibit pX-dependent formation of multinucleated cells, similar to human T-cell lymphotrop

97 are not optimized for capturing very large, multinucleated cells such as myotubes.

98 Some multinucleated cells such as those in muscles arise from

99 tions also exhibit an increased frequency of multinucleated cells, suggesting an impairment in cytoki

100 overexpression resulted in the production of multinucleated cells, suggesting the failure of proper c

101 y, SIRC cells expressing CD4 and CCR5 formed multinucleated cells (syncytia) upon exposure to BaL, a

102 rus-induced cell fusion and the formation of multinucleated cells (syncytia).

103 Osteoclasts are bone-resorbing multinucleated cells that are derived from the monocyte/

104 Myofibers are multinucleated cells that are formed, repaired and maint

105 leost Sternopygus macrurus, electrocytes are multinucleated cells that do not contract yet retain exp

106 mutant protein resulted in the formation of multinucleated cells that had replicated DNA.

107 cell fusion to form the fully differentiated multinucleated cells that mediate bone resorption.

108 pression are placental syncytiotrophoblasts, multinucleated cells that originate from fetal trophobla

109 Osteoclasts (OCs) are multinucleated cells that resorb bone and are essential

110 a 40% growth decrease and the appearance of multinucleated cells that result from defective cytokine

111 c clusters of adherent mononuclear and giant multinucleated cells that stained positive for tartrate-

112 ty of the population emerges from mitosis as multinucleated cells that subsequently undergo cell deat

113 sis and remarkably, elicits the formation of multinucleated cells that then arrest or die by mitotic

114 ell death was the appearance of enlarged and multinucleated cells that was related to the inhibition

115 Multinucleated cells were characterized as striated musc

116 RANKL immunolabeling and fewer TRAP-positive multinucleated cells were observed in the EA-treated gro

117 transduced cells formed increased numbers of multinucleated cells, which contained many more nuclei a

118 uce mitotic block and apoptosis and increase multinucleated cells with 8 N DNA content.

119 ression of mutated Nek8 results in enlarged, multinucleated cells with an abnormal actin cytoskeleton

120 matrix are all promoted by myosin-II, and so multinucleated cells with distended membranes--typical o

121 mRNA 5' untranslated region (5' UTR) led to multinucleated cells with striking morphological alterat

122 reased Nek2 protein leads to accumulation of multinucleated cells with supernumerary centrosomes.

123 ls of inflammatory arthritis have identified multinucleated cells with the phenotype of osteoclasts i

124 nockdown of I-2 by RNA interference produced multinucleated cells, with supernumerary centrosomes, mu