ライフサイエンスコーパス: multiparametric

1 nical trial, hybrid (18)F-choline PET/CT and multiparametric 3T MRI (mpMRI) of the pelvis were perfor

2 feedback to the user because of the advanced multiparametric algorithms used.

3 , and 17q and study of MYCN copy number; (b) multiparametric analysis by Laser-Scanning Cytometry of

4 We develop and test a Microscopic Multiparametric Analysis by Phasor projection of Polariz

5 A multiparametric analysis of hypoxia, extracellular pH, v

6 ging with antibody microarrays for rapid and multiparametric analysis of leukocytes from human blood.

7 A multiparametric analysis of rod apoptosis and mitochondr

8 nation to conduct a longitudinal integrative multiparametric analysis of seven immune parameters in v

9 Here, we utilize multiparametric analysis of time-lapse MT +TIP imaging d

10 Multiparametric analysis showed that classified voxels w

11 rative MR imaging features (n = 31) included multiparametric (anatomic and diffusion-, perfusion-, an

12 tate cancer identification using digitalized multiparametric anatomical and functional imaging and en

13 Purpose To evaluate the association of multiparametric and multiregional magnetic resonance (MR

14 Moreover, multiparametric and particular MRI sequences such as app

15 The multiparametric approach combines the information from d

16 We used a multiparametric approach combining flow cytometry, confo

17 This multiparametric approach complements the use of in vitro

18 We hypothesized that a multiparametric approach focused on islet cell metabolic

19 Here, we use a multiparametric approach for the evaluation of lipid nan

20 This classification endorses a multiparametric approach to diagnosis and outlines the m

21 This review discusses a multiparametric approach to the evaluation of musculoske

22 Our study demonstrates that a multiparametric approach using objective assessments foc

23 the identification of tumors improved with a multiparametric approach versus a strictly T2-weighted o

24 Its multiparametric approach, fusing spatial, contrast, and

25 This technique offers a multiparametric approach, providing an overview of the p

26 The recent advent of multiparametric approaches for myocardial deformation im

27 Multiparametric assessment of mean ADC, mean rCBV, and p

28 velopment of miniature cytometry devices for multiparametric blood analysis at the point of care or i

29 rols (n=13) prospectively underwent same day multiparametric cardiovascular magnetic resonance (cine,

30 ht to evaluate the diagnostic performance of multiparametric cardiovascular magnetic resonance (CMR)

31 as to establish the diagnostic accuracy of a multiparametric cardiovascular magnetic resonance (CMR)

32 tility of magnetic resonance imaging for the multiparametric characterization of breast tumor respons

33 rent diffusion coefficient (ADC) mapping for multiparametric characterization of prostate disease.

34 A multiparametric chemical optimization approach allowed t

35 Next, multiparametric classification was performed using lesio

36 Cardiac damage detectable by a multiparametric CMR approach can occur early in thalasse

37 This study aims at a retrospective multiparametric CMR assessment of myocardial iron overlo

38 For multiparametric CMR the sensitivity was 86.5% (95% CI 81

39 Within 1 month, patients underwent multiparametric CMR, including assessment of regional an

40 sonance (MR) imaging in comparison with full multiparametric contrast material-enhanced prostate MR i

41 rsion 2; only thereafter, the remaining full multiparametric contrast-enhanced MR images were read.

42 ) first reviewed only a fraction of the full multiparametric contrast-enhanced MR images, consisting

43 .1%, 483 of 542) was similar to that of full multiparametric contrast-enhanced MR imaging (87.2%, 473

44 Full multiparametric contrast-enhanced MR imaging allowed det

45 r detection rate of biparametric versus full multiparametric contrast-enhanced MR imaging and between

46 sy findings underwent state-of-the-art, full multiparametric contrast-enhanced MR imaging at 3.0-T in

47 are equivalent to those of conventional full multiparametric contrast-enhanced MR imaging protocols.

48 olume, shape, and texture features) from the multiparametric (contrast material-enhanced T1-weighted

49 We performed multiparametric cytofluorimetric analysis of PD-1(+) NK

50 lysis and allows the unbiased acquisition of multiparametric data at the single-cell level for hundre

51 Here, we report the use of multiparametric data extracted from a single marker and

52 However, the evaluation of multiparametric data generated via time-of-flight mass c

53 aphy, magnetic resonance spectroscopy yields multiparametric data, does not require radio-labeled tra

54 ere, we describe a novel approach to collect multiparametric datasets that describe the specificity,

55 Diagnostic values of multiparametric, DCE MR imaging, and DWI were calculated

56 tissues to be more effectively probed using multiparametric deep-tissue bioluminescence imaging.

57 The new multiparametric detection technology combines these two

58 urpose To evaluate the cost-effectiveness of multiparametric diagnostic magnetic resonance (MR) imagi

59 Multiparametric diagnostic models integrating different

60 Preclinical multiparametric diagnostics could help discover clinical

61 nce tool that identifies arbitrary nonlinear multiparametric discriminant functions directly from exp

62 would be more robust and sought to develop a multiparametric echocardiographic score for predicting C

63 A multiparametric echocardiographic score is helpful in se

64 crosensor, based on a polymer substrate, for multiparametric, electrochemical in vivo monitoring.

65 y infarcted, inflamed myocardium may provide multiparametric end points for clinical studies aiming a

66 Preoperative 1.5-T multiparametric endorectal MR images of 119 PC patients

67 men (mean age, 66.2 years +/- 6.9) underwent multiparametric endorectal prostate MR imaging at 3 T an

68 In conclusion, multiparametric evaluation of the spatial distributions

69 Multiparametric FACS analysis showed two populations of

70 Using IFN-gamma-ELISPOT and multiparametric FACS analysis, we characterized the indu

71 changes in GSH content and ROS formation by multiparametric FACS revealed that loss of intracellular

72 Multiparametric flow cytometric analyses revealed expres

73 Using multiparametric flow cytometric analysis, we assessed th

74 The results were contrasted with those of multiparametric flow cytometry (MFC) and allele-specific

75 at distinct risk; by contrast, low-sensitive multiparametric flow cytometry (MFC) immunophenotyping (

76 Multiparametric flow cytometry (MFC) in amyloid light-ch

77 Ten-color multiparametric flow cytometry (MFC) was performed on bo

78 A multiparametric flow cytometry analysis was performed to

79 secretion in the ELISpot was confirmed using multiparametric flow cytometry and largely attributed to

80 Through the use of multiparametric flow cytometry established by the Europe

81 Multiparametric flow cytometry for quantitation of labil

82 PCR and multiparametric flow cytometry have become the most popu

83 Advances in multiparametric flow cytometry have revealed that the fu

84 psies (N = 60 patients), we observed through multiparametric flow cytometry increased tumor-associate

85 Pre-HCT disease staging included 10-color multiparametric flow cytometry on bone marrow aspirates

86 In this protocol, we describe five multiparametric flow cytometry panels that can be used a

87 The purposes of this prospective, multiparametric flow cytometry study were to quantify he

88 Multiparametric flow cytometry was used to assess marker

89 nd (FL), IL-3, and GM-CSF and measurement by multiparametric flow cytometry yielded distinctive, high

90 %-100%]), 11 of 12 (92% [95% CI, 62%-100%]) (multiparametric flow cytometry), 14 of 21 (67% [95% CI,

91 Taking this into account, we analyzed, using multiparametric flow cytometry, the co-expression of the

92 he coccidioidal antigen preparation T27K and multiparametric flow cytometry, the in vitro frequency o

93 ch of high-throughput TCRbeta sequencing and multiparametric flow cytometry, we compared the TCR repe

94 SCNP is a multiparametric flow cytometry-based approach that enabl

95 longitudinally for vaccine-induced IR using multiparametric flow cytometry-based assays.

96 M. tuberculosis-specific CD4(+) T cells via multiparametric flow cytometry.

97 s and bronchoalveolar lavage fluid (BALF) by multiparametric flow cytometry.

98 lpha (TNF-alpha) production was analyzed via multiparametric flow cytometry.

99 -hr live-cell mixed leukocyte reaction using multiparametric flow cytometry.

100 cell phenotype analyzes were performed with multiparametric flow cytometry.

101 urface antigens (CD3, CD4, CD8, and CD19) by multiparametric flow cytometry.

102 -remitting multiple sclerosis patients using multiparametric flow cytometry.

103 ere will be expanded in the future to enable multiparametric functional analysis of immune cells orga

104 he MR modality, as well as the potential for multiparametric functional imaging in conjunction with P

105 Using the multiparametric high-content imaging method, we evaluate

106 g high-resolution 3D confocal microscopy and multiparametric image analysis, to simultaneously survey

107 ed with 18 cases of eczematous dermatitis by multiparametric image cytometry.

108 The lab-on-a-chip studies with live-cell multiparametric imaging allow understanding of physiolog

109 patient comfort and increased throughput to multiparametric imaging and are evaluated and reviewed i

110 We investigated whether multiparametric imaging by cardiovascular magnetic reson

111 paving the way for the concept of multimodal multiparametric imaging for future more widespread clini

112 Multiparametric imaging has many potential clinical role

113 ssess the correlation and reproducibility of multiparametric imaging in head and neck cancer patients

114 Nanoscale multiparametric imaging of living bacteria reveals that

115 sent a protocol to apply FD-based AFM to the multiparametric imaging of native proteins under physiol

116 hodology for and investigated the utility of multiparametric imaging of tumor hypoxia and perfusion w

117 Multiparametric imaging of tumor perfusion and hypoxia w

118 Multiparametric imaging offers the opportunity to study

119 A multiparametric imaging phenotype vector was extracted f

120 Multiparametric imaging reveals that contractions consti

121 The multiparametric imaging system presented here offers a s

122 Noninvasive multiparametric imaging techniques are emerging tools th

123 The promise of PET/MRI includes multiparametric imaging to further improve diagnosis and

124 Such knowledge may extend the utility of multiparametric imaging to yield information regarding c

125 that it is possible to perform quantitative multiparametric imaging with heterogeneous RF fields, an

126 nical risk stratification in HCM but require multiparametric imaging with high spatial and temporal r

127 In multiparametric imaging with the integrated PET/MR scann

128 n exposure, higher soft-tissue contrast, and multiparametric imaging).

129 , including standardization, validation, and multiparametric imaging, must be taken before these para

130 interaction analysis using double RNAi and a multiparametric, imaging-based assay.

131 Using the VectraR automated multiparametric immunofluorescence technique, we quantif

132 e cancer cells in nude mice and suggest that multiparametric in situ hybridization analyses can be us

133 Collectively, the data show that multiparametric in situ hybridization analysis for sever

134 recombinant in vivo ROS probes would enable multiparametric in vivo ROS detection.

135 d technique competent for the acquisition of multiparametric information by creating a tissue section

136 Here we propose a validated methodology for multiparametric kinase biosensing in living cells using

137 This study presents a multiparametric label-free analysis gathering surface pl

138 , proton and phosphorus MR spectroscopy, and multiparametric liver MR, including hepatic proton MRS,

139 adenocarcinoma in the context of colocalized multiparametric magnetic resonance (MR) imaging and hist

140 Purpose To determine if multiparametric magnetic resonance (MR) imaging mapping

141 Purpose To develop multiparametric magnetic resonance (MR) imaging models t

142 Multiparametric magnetic resonance (MR) imaging of the p

143 prostatectomy and underwent preoperative 3-T multiparametric magnetic resonance (MR) imaging, includi

144 ong peripheral zone (PZ) lesions seen at 3-T multiparametric magnetic resonance (MR) imaging.

145 Using multiparametric magnetic resonance (MR) techniques, we c

146 eity in hepatocellular carcinoma (HCC) using multiparametric magnetic resonance imaging (mpMRI), and

147 Multiparametric Magnetic Resonance Imaging (MRI) can pro

148 Longitudinal multiparametric magnetic resonance imaging (MRI) followi

149 Multiparametric magnetic resonance imaging of his prosta

150 A novel multiparametric magnetic resonance microscopy (MRM) appr

151 itol on brain edema and oxygenation, using a multiparametric magnetic resonance-based approach (n = 1

152 fraction were subsequently measured using a multiparametric magnetic resonance-based approach to est

153 e call FISH-Flow, allows for high-throughput multiparametric measurements of gene expression, a task

154 Flow cytometry is a ubiquitous, multiparametric method for characterizing cellular popul

155 l. describes the application of quantitative multiparametric methods to a genome-wide RNAi screen for

156 iological and biomimetic systems for dynamic multiparametric microenvironmental control of emergent a

157 applications in bacteria, especially in the multiparametric mode, remain limited.

158 y was evaluated by comparing the AUC for the multiparametric model and the single best-performing qua

159 y considered when selecting metrics to build multiparametric models.

160 tomatized analysis, our results suggest that multiparametric molecular and functional imaging may be

161 imaging-guided interventions, which provide multiparametric morphologic and functional information a

162 raphy (PET) and computed tomography (CT) and multiparametric (MP) 3-T endorectal MR imaging before ro

163 nically important prostate cancers missed at multiparametric (MP) magnetic resonance (MR) imaging.

164 mation that maps brain networks derived from multiparametric MR data with metabolic information from

165 picious for cancer as benign or malignant on multiparametric MR images first without and subsequently

166 nts with cancer-suspicious regions (CSRs) on multiparametric MR images obtained at 3 T.

167 review board-approved HIPAA-compliant study, multiparametric MR images were acquired with an endorect

168 suspicious for cancer were identified on 3-T multiparametric MR images.

169 ample +/- 21), intermediately suspicious via multiparametric MR imaging (31 mutations per sample +/-

170 ns per sample +/- 19), mildly suspicious via multiparametric MR imaging (37 mutations per sample +/-

171 Multiparametric MR imaging (diffusion-weighted MR imagin

172 for 134 patients who underwent preoperative multiparametric MR imaging (T2 weighted, diffusion weigh

173 Multiparametric MR imaging (T2-weighted MR imaging, MR s

174 Multiparametric MR imaging (T2-weighted, dynamic contras

175 were evaluated, 110 with prostatectomy after multiparametric MR imaging and 53 with negative multipar

176 robot-assisted radical prostatectomy without multiparametric MR imaging and IFS analysis.

177 diagnosed as having local recurrence by both multiparametric MR imaging and PET/CT, 22 (36.1%) were c

178 ions, and this reflected concordance between multiparametric MR imaging and resultant histopathologic

179 tiparametric MR imaging and 53 with negative multiparametric MR imaging and systematic biopsy finding

180 enabled spatial mapping between preoperative multiparametric MR imaging and the gland.

181 Conclusion Multiregion spatial multiparametric MR imaging and whole-exome radiogenomic

182 Results Radiogenomic multiparametric MR imaging and whole-exome spatial chara

183 (11)C-choline PET/CT and pelvic multiparametric MR imaging are complementary for restagi

184 , and these results were similar to those of multiparametric MR imaging assessment of features in thi

185 ment of prostate-specific antigen level, and multiparametric MR imaging at 3, 6, and 12 months.

186 .73 ng/mL (median, 4.39 ng/mL) who underwent multiparametric MR imaging at 3.0 T before radical prost

187 Multiparametric MR imaging at 7 T of the breast eliminat

188 with prostate cancer (n = 133) underwent 3-T multiparametric MR imaging before prostatectomy.

189 ith a diagnosis of prostate cancer underwent multiparametric MR imaging before surgery for treatment.

190 the characterization of prostate lesions at multiparametric MR imaging by increasing reading specifi

191 Data System (PI-RADS) version 2 for prostate multiparametric MR imaging by using data from a multirea

192 Volumetric analysis of multiparametric MR imaging data may have potential as a

193 Multiparametric MR imaging demonstrated either excellent

194 A quantitative multiparametric MR imaging evaluation that incorporated

195 ent was evaluated on the basis of subjective multiparametric MR imaging features.

196 nd CAPRA scoring systems) were compared with multiparametric MR imaging findings for predicting AS ca

197 to compare (11)C-choline PET/CT with pelvic multiparametric MR imaging for detection of recurrent pr

198 ed sensitivity, specificity, and accuracy of multiparametric MR imaging for diagnosing local recurren

199 dates (P < .005 for all, chi(2) test), while multiparametric MR imaging had a sensitivity of 93%, a P

200 The clinical use of 7-T multiparametric MR imaging is feasible, provides good or

201 Conclusion Serial multiparametric MR imaging mapping can be used to evalua

202 Thus, if used clinically, 7-T multiparametric MR imaging may have potentially obviated

203 Conclusion Quantitative multiparametric MR imaging models developed by using cor

204 Before bilateral multiparametric MR imaging of the breast at 7 T, all pat

205 ostate-specific antigen levels who underwent multiparametric MR imaging of the prostate and subsequen

206 hted, and dynamic contrast material-enhanced multiparametric MR imaging of the prostate before radica

207 T/CT, 22 (36.1%) were correctly diagnosed by multiparametric MR imaging only, 6 (9.8%) could not be d

208 scale score, >/=3) focus at prebiopsy 1.5-T multiparametric MR imaging performed with T2-weighted, d

209 rotocol versus a standard six-pulse sequence multiparametric MR imaging protocol for detection of cli

210 e sequences compared with that of a standard multiparametric MR imaging protocol.

211 Multiparametric MR imaging provides useful additional in

212 Thirty consecutive 1.5-T multiparametric MR imaging studies (with T2-weighted, di

213 of random biopsies, and targets depicted at multiparametric MR imaging underwent transrectal US-guid

214 receiver-operating-characteristic curves of multiparametric MR imaging versus PET/CT for the diagnos

215 Multiparametric MR imaging was performed of abdominal tu

216 uided biopsy, suspicious lesions detected at multiparametric MR imaging were scored by five readers w

217 Multiparametric MR imaging with endorectal coil is super

218 who underwent both (11)C-choline PET/CT and multiparametric MR imaging with endorectal coil.

219 Multiparametric MR imaging yielded a sensitivity of 100%

220 ed who had prostate cancer and had undergone multiparametric MR imaging, including T2-weighted, diffu

221 y and in a masked manner reviewed PET/CT and multiparametric MR imaging, respectively.

222 evidence of the positive clinical effect of multiparametric MR imaging-directed IFS analysis for pat

223 tive biopsy results and positive findings at multiparametric MR imaging.

224 zation and segmentation of rectal cancers on multiparametric MR imaging.

225 ent robotic transperineal mapping biopsy and multiparametric MR imaging.

226 ere treatment-naive with endorectal coil 3-T multiparametric MR imaging.

227 taging of local disease by comparing it with multiparametric MRI (mpMRI) and radical prostatectomy (R

228 portant imaging modalities in focal therapy, multiparametric MRI (mpMRI) and ultrasonography.

229 Today, advances in multiparametric MRI allow for detection and targeted bio

230 rostate cancer, and who could safely undergo multiparametric MRI and have a general anaesthetic.

231 atic biopsy and sampling labeling along with multiparametric MRI and magnetic resonance-targeted biop

232 tandardized uptake values were compared with multiparametric MRI and pathology.

233 tz and colleagues, the authors have combined multiparametric MRI and PET imaging to address the impor

234 rent imaging modalities, only ultrasound and multiparametric MRI are intimately involved in the detec

235 95% CI 83-99) had no evidence of disease on multiparametric MRI at 12 months.

236 lvic (11)C-acetate PET/CT for 30 min and 3-T multiparametric MRI before prostatectomy.

237 Multiparametric MRI can be used to direct prostate biops

238 We propose the use of patient-specific multiparametric MRI consisting of Dixon MRI and proton-d

239 The focus of this study is to review multiparametric MRI in the detection and risk stratifica

240 This work demonstrates that multiparametric MRI is a powerful tool for the assessmen

241 Multiparametric MRI is a useful tool in the initial asse

242 To date, multiparametric MRI is the most effective imaging techni

243 Multiparametric MRI of the prostate gland is a relativel

244 it may be difficult to detect using current multiparametric MRI protocols.

245 derived from combined (18)F-fluciclovine PET/multiparametric MRI show potential for detection and cha

246 Combined (18)F-fluciclovine PET/multiparametric MRI shows potential for improving detect

247 The DRs of (18)F-choline PET/CT and multiparametric MRI were 56% and 74%, respectively.

248 (64)CuCl2 PET/CT, (18)F-choline PET/CT, and multiparametric MRI within 15 d of each other.

249 role of transperineal template biopsies and multiparametric MRI, both for patient selection and in i

250 ith a margin of normal tissue, identified on multiparametric MRI, template prostate-mapping biopsies,

251 nd normal prostate tissue in comparison with multiparametric MRI, whole-mount histopathology, and cli

252 on, especially when used in combination with multiparametric MRI.

253 dual patients will most likely result from a multiparametric (MRI/MRSI/DTI/DCE) exam using 3T magneti

254 onal neural network (CNN) was trained on the multiparametric MRIs of the discovery set to classify ea

255 The multiparametric nature of nanoparticle self-assembly mak

256 To this intent, we present here a multiparametric, noninvasive approach based on in vivo (

257 mapping with motion and contraction; (6) new multiparametric optical mapping techniques; and (7) phot

258 Multiparametric optimization of early hits with moderate

259 xisting techniques, and also allows powerful multiparametric paired statistics.

260 variately associated with sensitization, but multiparametric PCA suggested a specific inflammatory re

261 Using multiparametric permeabilized-cell flow cytometric analy

262 Leveraging the power of multiparametric PET/MRI in this manner has the potential

263 Here, we performed a multiparametric phenotypic characterization and unbiased

264 Using multiparametric phospho-flow and mass cytometry, we meas

265 Means for high-density multiparametric physiological mapping and stimulation ar

266 Future studies should explore the multiparametric potential of MRI.

267 al heterogeneity in this model resulted in a multiparametric profile based on [(18)F]Fluorodeoxygluco

268 taneously, thus enabling pairwise-correlated multiparametric profiling of lymphocyte interactions ove

269 standard." INTERVENTIONS: Patients underwent multiparametric prostate magnetic resonance imaging to i

270 Multiparametric prostate MR imaging at 1.5 T was perform

271 Although we agree that improvements in multiparametric radial velocity (RV) modeling are necess

272 ry brain cells, a microfluidic device, and a multiparametric readout approach.

273 The multiparametric readout takes into account the intrinsic

274 lied to fluorescence-based assays to extract multiparametric readouts of treatment effects for hetero

275 ions of several known CLASP interactors, its multiparametric resolution reveals more detailed functio

276 e previously developed a reliable method for multiparametric scaling of Fermi contacts to achieve fas

277 A simple multiparametric scoring function (AB-MPS) was devised th

278 A multiparametric sequence-specific model for predicting p

279 Mass cytometry is developing as a means of multiparametric single-cell analysis.

280 Multiparametric single-cell mass cytometry demonstrates

281 s DCs, were viable in tumors, we carried out multiparametric staining of 9L tumors, using phycoerythr

282 al snapshots soon after DU onset, this novel multiparametric statistical approach for comparative epi

283 Partial Least Squares Discriminant Analysis) multiparametric statistical methods allowed the cocoa be

284 All participants underwent multiparametric structural and functional magnetic reson

285 Standardization of multiparametric transrectal ultrasound and mpMRI is of p

286 rpose To evaluate the diagnostic accuracy of multiparametric ultrasonography (US) consisting of gray-

287 Conclusion Multiparametric US allows for a reliable differentiation

288 When multiparametric volumes from two observers were combined