ライフサイエンスコーパス: multiple round of

1 ATP hydrolysis recycles XKCM1/XKIF2 for multiple rounds of action by dissociating a XKCM1/ XKIF2

2 ed to mediate a fast reassociation, enabling multiple rounds of activation.

3 molecules along these binding sites required multiple rounds of adenosine triphosphate (ATP) hydrolys

4 However, most therapeutics require multiple rounds of administration and can have toxic sid

5 -interacting protein (HHIP) and subjected to multiple rounds of affinity maturation through the scree

6 ative end stage of replicative senescence by multiple rounds of Ag-driven cell division.

7 in cell cultures of CD8(+)CD28(+) following multiple rounds of Ag-driven proliferation, reaching the

8 ion of the Escherichia coli host cells; (ii) multiple rounds of an intracellular selection process to

9 hibit long-term self-renewal capacity during multiple rounds of androgen-mediated regeneration after

10 grammatic relevance of this evaluation after multiple rounds of antibiotic treatments is unclear.

11 tination of distributive substrates requires multiple rounds of APC binding, which render it sensitiv

12 sts are the CNS progenitor cells and undergo multiple rounds of asymmetric cell division, ;budding of

13 SecA performs multiple rounds of ATP hydrolysis before dissociating fr

14 re the enzyme binds to the DNA and catalyzes multiple rounds of ATP hydrolysis before dissociating.

15 ur data also show that MuB does not catalyze multiple rounds of ATP hydrolysis while remaining bound

16 ains associated with the microtubule through multiple rounds of ATP hydrolysis.

17 ng among different open states by undergoing multiple rounds of ATP hydrolysis.

18 folding rate enhancements without undergoing multiple rounds of ATP-induced binding and release from

19 are shifted to low Mg(++) , PhoQ engages in multiple rounds of autophosphorylation and phosphotransf

20 tasis, and function of B lymphocytes involve multiple rounds of B-cell receptor (BCR)-controlled prol

21 Five RCTs with multiple rounds of biennial screening with guaiac-based

22 icating that single EB1 molecules go through multiple rounds of binding and dissociation during micro

23 GR can undergo multiple rounds of binding and dissociation to the palin

24 ubunits of GroEL, and might help explain why multiple rounds of binding and hydrolysis are required f

25 uires both GroEL and GroES, and proceeds via multiple rounds of binding and release.

26 cord with the iterative annealing mechanism, multiple rounds of binding, partial unfolding, and relea

27 For BioB to catalyze multiple rounds of biotin synthesis, the [2Fe-2S](2+) cl

28 nd the variable length of each gene requires multiple rounds of BLAST searches for a single IG sequen

29 imple example of processivity, as defined by multiple rounds of catalysis without release of substrat

30 at this conformational change is stable over multiple rounds of catalysis.

31 Transient TCR stimulation induces multiple rounds of CD8 T cell division without further r

32 evolution of an oligonucleotide pool through multiple rounds of CE-SELEX selection against the target

33 er the signal appears, proliferating through multiple rounds of cell division before committing to a

34 least 1000-fold, HA-specific T cells undergo multiple rounds of cell division before reaching a nonre

35 l status of a gene can be maintained through multiple rounds of cell division during development.

36 ergy avoidance: the few T cells that undergo multiple rounds of cell division during overt CD28 costi

37 CD4(+) T cells that undergo multiple rounds of cell division during primary Ag chall

38 og-based lineage-tracing technique to detect multiple rounds of cell division in vivo.

39 does not rely on candidate markers to track multiple rounds of cell division in vivo.

40 strated evidence of blastogenesis, underwent multiple rounds of cell division leading to their clonal

41 ed Otx/bHLH pathway act sequentially through multiple rounds of cell division on the right to relay a

42 ribution of intracellular nanoparticles upon multiple rounds of cell division was investigated.

43 h) to Ag and B7-1 is sufficient to stimulate multiple rounds of cell division, but clonal expansion a

44 When this process is repeated during multiple rounds of cell division, it leads to patterns o

45 ic cells, while long-term memory can survive multiple rounds of cell division.

46 late diverse mutations in a DNA barcode over multiple rounds of cell division.

47 same domain that is stably inherited through multiple rounds of cell division.

48 d to specify a variety of cell types through multiple rounds of cell divisions or to exert seemingly

49 The liver is a complex organ that requires multiple rounds of cell fate decision for development an

50 in-dependent kinase 2 (Cdk2) is required for multiple rounds of centrosome duplication in Xenopus egg

51 Multiple rounds of centrosome reproduction were blocked

52 the sensitive A2780S ovarian cancer line to multiple rounds of cisplatin treatments followed by reco

53 The transferrin receptor (TfR) undergoes multiple rounds of clathrin-mediated endocytosis and ree

54 erved in prostate cancer may be explained by multiple rounds of clonal expansion.

55 l initiation is a cyclical process involving multiple rounds of coactivator assembly and disassembly.

56 equires that Vps10p must recycle and perform multiple rounds of CPY sorting.

57 After multiple rounds of cycling mutagenesis and DNA shuffling

58 ure sufficient amino acids are available for multiple rounds of daughter generation.

59 However, multiple rounds of degeneration/regeneration in conditio

60 ontrols) were given azoxymethane followed by multiple rounds of dextran sodium sulfate (DSS) to induc

61 several PRRSV strains were isolated through multiple rounds of differential density gradient centrif

62 initially yielded IL-5(-) Th2, but required multiple rounds of differentiation to generate IL-5(+) T

63 ereus (CiP) heme peroxidase was subjected to multiple rounds of directed evolution in an effort to pr

64 or (variable region, Vbeta) was subjected to multiple rounds of directed evolution using yeast displa

65 Finally, a given RE can undergo multiple rounds of display exocytosis.

66 lic VZ cells, SVZa cells continue to undergo multiple rounds of division and differentiation before b

67 Thus, a fraction of cells undergo multiple rounds of division without increasing in number

68 The schizont stage is associated with multiple rounds of DNA replication and nuclear division

69 a key cell-cycle regulator that orchestrates multiple rounds of DNA replication throughout schizogony

70 lure of the control mechanisms can result in multiple rounds of DNA replication without cell division

71 accharomyces pombe can be induced to perform multiple rounds of DNA replication without intervening m

72 ific internal eliminated sequences (IES) and multiple rounds of DNA replication.

73 deltacig2 cells are defective in undergoing multiple rounds of DNA replication.

74 TPX2-injected embryos biochemically undergo multiple rounds of DNA synthesis and mitosis, and arrest

75 T-antigen to oriP is sufficient to initiate multiple rounds of DNA synthesis from oriP during each c

76 epithelium disrupts the cell cycle, causing multiple rounds of DNA synthesis without proper cell div

77 t cells in vitro, but were unable to undergo multiple rounds of DNA synthesis, demonstrating that the

78 ing that copy-up pi proteins do not initiate multiple rounds of DNA synthesis.

79 n some transformed cells, centrioles undergo multiple rounds of duplication (reduplication) during pr

80 centriole amplification in cells undergoing multiple rounds of duplication without preventing the fo

81 ggest that the multisubstrate dNKs underwent multiple rounds of duplications with differential retent

82 an accessory ATPase, ClpV, that facilitates multiple rounds of effector delivery.

83 opose instead that this activity can lead to multiple rounds of elicitor recognition, providing a mea

84 rnalization involving receptor recycling and multiple rounds of endocytosis.

85 ly, these abnormal cystocytes do not undergo multiple rounds of endoreplication as the nurse cells do

86 In cases when multiple rounds of enrichment are required, the software

87 Multiple rounds of enrichment with a target plasmid repr

88 false positive or negative rates necessitate multiple rounds of enrichment.

89 the peroxisome membrane, but participates in multiple rounds of entry into the peroxisome matrix and

90 This scheme allows us to perform multiple rounds of evolution (addressing approximately 1

91 cells exposed to adriamycin, leading to the multiple rounds of exchange between EPCs and mature cell

92 neurotransmission, synaptic vesicles undergo multiple rounds of exo-endocytosis, involving recycling

93 ease is further sustained by DCVs undergoing multiple rounds of exocytosis.

94 JBPs and associated transposons as involving multiple rounds of expansion with concomitant lineage so

95 eds to be an iterative process that requires multiple rounds of experimental validation together with

96 ction and then isolated clones that survived multiple rounds of exposure to the virus.

97 labor-intensive, iterative process requiring multiple rounds of extraction and polymerase chain react

98 Multiple rounds of extraction, purification, followed by

99 igand-binding library clones are selected by multiple rounds of fluorescence-activated cell sorting.

100 romoter and selected for high activity using multiple rounds of fluorescence-activated cell sorting.

101 Many vacuoles in the population undergo multiple rounds of fusion; methods are presented for dis

102 28 loci within genomes was generated through multiple rounds of gene duplication followed by function

103 Multiple rounds of genome duplication and extensive gene

104 injection activated the cardiac program, and multiple rounds of GMT protein delivery significantly im

105 t respond to sudden nutrient limitation with multiple rounds of growth and division before differenti

106 By multiple rounds of growth in the mutator strain, and inc

107 Multiple rounds of heat-cool extension cycles, akin to P

108 hat Gp59 from the HLC is recycled to promote multiple rounds of helicase assembly on Gp32-ssDNA, a ca

109 for algal-gene origin in ciliates either via multiple rounds of horizontal gene transfer (HGT) from a

110 esent-day bread wheat genome is a product of multiple rounds of hybrid speciation (homoploid and poly

111 s showed that DNA loss was minimal, allowing multiple rounds of hybridization.

112 premature death of GC B cells might preclude multiple rounds of hypermutation necessary to generate a

113 far, APC-based vaccinations usually include multiple rounds of immunization.

114 We use off-the-shelf antibodies for multiple rounds of immunolabeling and imaging of a tissu

115 een accomplished by DNA shuffling, involving multiple rounds of in vitro recombination and mutation o

116 Comparison of single and multiple rounds of in vitro run-off transcription sugges

117 suited for prohead binding, were obtained by multiple rounds of in vitro selection.

118 nal splicing enhancers were then selected by multiple rounds of in vitro splicing in nuclear extracts

119 IL-23 maintains the Th17 phenotype over multiple rounds of in vitro stimulation most efficiently

120 ffectors in the lung was observed only after multiple rounds of in vitro stimulation of RSV G-specifi

121 a susceptible cancer cell line (P0/TC-1) to multiple rounds of in vivo immune selection.

122 uppression of BCR-ABL1expression, even after multiple rounds of induction and reversion.

123 duction in sensitivity is sufficient to keep multiple rounds of infection from terminating in the pre

124 biased cell-based screening system involving multiple rounds of infection in a 96-well format.

125 The high-titer viremia development implies multiple rounds of infection that proceed in the backgro

126 transgenic mouse cells remains available for multiple rounds of infection with different ASLV vectors

127 tant viruses, we are able to select, through multiple rounds of infection, those sequences imparting

128 presumably due to the compounding effects of multiple rounds of infection.

129 immunological parameters can be increased by multiple rounds of infections and praziquantel-induced c

130 ms a stable complex with DNA and can promote multiple rounds of initiation by polymerase.

131 FIIIB)-DNA complexes that are stable through multiple rounds of initiation.

132 form of the protease and as such engages in multiple rounds of interaction with substrate proteins,

133 dred sixty-seven patients, most of them with multiple rounds of IVM, were recruited in areas with IVM

134 fusion and to track single vesicles through multiple rounds of kiss-and-run and reuse, without pertu

135 nized Escherichia coli cells for survival to multiple rounds of lethal ampicillin exposure.

136 However, multiple rounds of library subtraction resulted in high

137 results argue against the accepted view that multiple rounds of low-rate mutagenesis and stepwise sel

138 f buffers and ionic strengths and can endure multiple rounds of lyophilization while retaining high b

139 e methyl groups after transfer to facilitate multiple rounds of lysine methylation.

140 association of Cdt1 with ORC is required for multiple rounds of Mcm2-7 loading.

141 ATP hydrolysis by ORC is required for multiple rounds of Mcm2-7 loading.

142 lt as transfer cultures failed to grow after multiple rounds of media transfer.

143 ent than the typical silver development, and multiple rounds of metal development were found to incre

144 , surrounded by ICAM-1, created by combining multiple rounds of microcontact printing on a single sur

145 enhancing the ability of MCAK to recycle for multiple rounds of microtubule depolymerization, and pre

146 eiotic event within the basidium followed by multiple rounds of mitosis.

147 s are selected in an evolutionary process of multiple rounds of mutation and selection.

148 The system provides for multiple rounds of mutation in a window up to 200 base p

149 s during the consolidation period results in multiple rounds of NMDA-receptor-dependent synaptic rein

150 zed by checkpoint proteins break and undergo multiple rounds of nonallelic recombination to form tran

151 gillus nidulans, germinating conidia undergo multiple rounds of nuclear division before forming a sep

152 gillus nidulans, germinating conidia undergo multiple rounds of nuclear division before the formation

153 he filamentous fungus, Aspergillus nidulans, multiple rounds of nuclear division occur before cytokin

154 om the nucleus to allow its participation in multiple rounds of nuclear import.

155 llized poliovirus elongation complexes after multiple rounds of nucleotide incorporation.

156 -strand polymerase acted processively during multiple rounds of Okazaki fragment synthesis, i.e. the

157 we focused, was fast, bistable and supported multiple rounds of on/off switching.

158 Multiple rounds of osmotic stress followed by recovery o

159 ntering each other many times and undergoing multiple rounds of ParM-dependent segregation in a singl

160 The RNAi cells undergo multiple rounds of partial cytokinesis and accumulate nu

161 ity sites hydrolyze ATP slowly, they support multiple rounds of peptide hydrolysis, indicating that A

162 he rRNA gene promoter is necessary to direct multiple rounds of Pol I transcription initiation.

163 nal domain of UBF is important for promoting multiple rounds of Pol I transcription.

164 y of the preinitiation complex or facilitate multiple rounds of polymerase recruitment.

165 RNA molecule across Pol II genes, suggesting multiple rounds of pre-initiation complex assembly and d

166 n help determine the sequence of products in multiple rounds of processive recombination and distingu

167 ESCRT-III protein lattice, thereby allowing multiple rounds of protein sorting and vesicle formation

168 to the native state in a reaction involving multiple rounds of quantized ATP hydrolysis by GroEL.

169 ion, reducing the efficiency of repair after multiple rounds of radiation, as used in fractionated ra

170 ructures in Drosophila melanogaster requires multiple rounds of Ras signaling followed by dramatic ep

171 retained full enzymatic activity, even after multiple rounds of recycling.

172 te transcription at high levels by promoting multiple rounds of reinitiation of transcription.

173 NA primer and preventing dissociation during multiple rounds of repeat addition.

174 se cells increased beyond 4N indicating that multiple rounds of replication had occurred without an i

175 prevent the spread of influenza virus during multiple rounds of replication in vitro and extend survi

176 with mutant viruses which were incapable of multiple rounds of replication in vivo failed to induce

177 following rapid serial passages in vitro and multiple rounds of replication in vivo.

178 lication origins, or by viral protein-driven multiple rounds of replication initiation at viral origi

179 n in which use of a viral mutagen would over multiple rounds of replication lead to the lethal accumu

180 rry the memory of the silenced state through multiple rounds of replication, even when the capacity t

181 that can measure replication efficiency over multiple rounds of replication.

182 of the replicon RNA was changed to an A upon multiple rounds of replication.

183 of the inserted LCR, probably as a result of multiple rounds of replication.

184 In contrast, during lytic growth, multiple rounds of replicative transposition amplify the

185 exists as a stable mRNP that may facilitate multiple rounds of ribosomal loading during translation

186 enes can be stacked to the same site through multiple rounds of RMCE.

187 Each let-7-containing complex directs multiple rounds of RNA cleavage, which explains the rema

188 on-enzymatic template copying, which renders multiple rounds of RNA replication impossible.

189 expression of Trident is required to prevent multiple rounds of S phase in the heart and the liver.

190 2 caused mammary epithelial cells to undergo multiple rounds of S phase without cell division.

191 After multiple rounds of screening 13 mutants that failed to c

192 , however, is an iterative process requiring multiple rounds of selection and amplification that dema

193 gans genomic DNA, we devised a procedure for multiple rounds of selection and amplification that yiel

194 CPR allows for multiple rounds of selection and enrichment to identify

195 Through multiple rounds of selection using BNL as a control, we

196 6) different clones) in Escherichia coli and multiple rounds of selection with the alkylating agent m

197 After multiple rounds of selection, candidate Sin(-) mutant vi

198 After multiple rounds of selection, the cells that adapted thr

199 was passaged in murine fibroblast cells for multiple rounds of selection.

200 y the parental sequence, and then only after multiple rounds of selection.

201 y of the ssDNA pools that remains even after multiple rounds of selection.

202 s (approximately 10(13)) can be subjected to multiple rounds of selective pressure, amplification, an

203 Similar to the human, ferret oRGs underwent multiple rounds of self-renewing divisions but were more

204 te SIN at or upstream of cdc7, ensuring that multiple rounds of septation do not occur.

205 cell cycle arrest in late mitosis and permit multiple rounds of septation.

206 multilineage differentiation potential after multiple rounds of serial bone marrow transfer over a pe

207 RssB participates in multiple rounds of sigma(S) degradation, demonstrating i

208 Using molecular dynamics simulations and multiple rounds of simulated annealing, we then relaxed

209 t yield high levels of siRNAs, indicative of multiple rounds of siRNA amplification, are disproportio

210 ome unlinking can instead be accomplished by multiple rounds of site-specific recombination.

211 itu hybridization, immunohistochemistry with multiple rounds of staining and de-staining in non-secti

212 This novel phenotype is stable over multiple rounds of stimulation in the presence of Th1-in

213 ssor cells (Ts) can be generated in vitro by multiple rounds of stimulation with allogeneic, xenogene

214 re Th17 cells, but cells that have undergone multiple rounds of stimulation, either in vivo during a

215 egulatory "gating" mechanism normally blocks multiple rounds of strand exchange and triggers product

216 ggest that CRAG degradation proceeds through multiple rounds of substrate binding to GroEL, followed

217 urther demonstrate that these EGSs engage in multiple rounds of substrate recognition while assisting

218 xb1 and varphiC31, we were able to carry out multiple rounds of successive and targeted DNA integrati

219 Transcription entailed multiple rounds of synthesis, with transcript ratios rem

220 C. elegans relative to C. briggsae is due to multiple rounds of tandem duplication and translocation

221 ired for miRNA processing, RISC assembly, or multiple rounds of target-RNA cleavage.

222 Our approach utilizes multiple rounds of targeted imaging at different scales

223 vidual elongation complexes do not engage in multiple rounds of TCR with successive lesions.

224 e internal RNA template and in some cases by multiple rounds of template copying before product disso

225 n retain its single-stranded product through multiple rounds of template dissociation and repositioni

226 Planning Estimation Model and uses data from multiple rounds of the Demographic and Health Survey, th

227 TP binding step becomes rate-limiting in the multiple rounds of the dNTP incorporation by MuLV RT, es

228 With multiple rounds of this energy-dissipative recycling, we

229 ctive synthesis of the transcript or undergo multiple rounds of transcript slipping.

230 This requires multiple rounds of transcription and thus cannot rely so

231 as a substantially higher ability to support multiple rounds of transcription at certain promoters, s

232 ses with negative supercoiling and also with multiple rounds of transcription compared with single ev

233 Experiments using single and multiple rounds of transcription indicate that these chr

234 factors SNAP(c), TBP, Brf2, and Bdp1 directs multiple rounds of transcription initiation and terminat

235 nd that Pol II-TFIIF was active in promoting multiple rounds of transcription while Pol II-Med was ne

236 re promoter is very inefficient but supports multiple rounds of transcription.

237 t not only Set1/COMPASS recruitment but also multiple rounds of transcription.

238 here was no functional 'memory' facilitating multiple rounds of transcription.

239 BP-TAF complexes, remain promoter- bound for multiple rounds of transcription.

240 learance and/or reinitiation, as measured by multiple rounds of transcription.

241 kedly different yields of RNA product during multiple rounds of transcription.

242 actor, recruits RNA polymerase (Pol) III for multiple rounds of transcription.

243 re-initiation complex that is stable through multiple rounds of transcription.

244 hexasome is retained on the template during multiple rounds of transcription.

245 does not require isolation of progenitors or multiple rounds of transfection.

246 plasmid, and up to 18 genes altogether after multiple rounds of transformation or sexual crosses.

247 er RG cells generate IP cells, which undergo multiple rounds of transit amplification in the outer su

248 her, our data suggest that mys has undergone multiple rounds of transposition since the peromyscine r

249 However, because multiple rounds of turnover were observed, we conclude t

250 aged between 9 to 23 years old responded to multiple rounds of ultimatum game proposals.

251 composed of hundreds of unique genes, during multiple rounds of vegetative growth when sporulation is

252 ities) Vps4 provides the energy required for multiple rounds of vesicle formation.

253 Multiple rounds of vesicle fusion in the absence of NSF