ライフサイエンスコーパス: multiplex

1 become layers of a larger structure called a multiplex.

2 throughput implementation, and (3) be easily multiplexed.

3 iaturization and possess the potential to be multiplexed.

4 sitive and accurate miRNA assay suitable for multiplexing.

5 ar identifiers; and (4) easy scalability and multiplexing.

6 next generation sequencing (NGS) due to its multiplexing.

7 es were comparable to those obtained without multiplexing.

8 paving the way of such optical platforms for multiplexing.

9 nctions such as filtering, spectroscopy, and multiplexing.

10 uorescence lifetime imaging(1-3) and spatial multiplexing(1,4,5) have offered information content and

11 By reshaping the orthogonal frequency multiplexed (16-QAM OFDM) stream with sidelobe filtering

12 y of 80 Gbit/s up to 100-m-roundtrip link by multiplexing 2 OAM beams, each carrying a 40-Gbit/s quad

13 We achieve multiplexed 3D super-resolution imaging at sample depths

14 ten lack sensitivity and can be difficult to multiplex across many pathogens.

15 roach offers an account of LIP activity as a multiplexed amalgam of sensory, cognitive, and motor-rel

16 Furthermore, multiplex analysis allows for a quantification of distin

17 combined single-cell mass cytometry with the multiplex analysis of relevant plasma cytokines to compr

18 novel, highly scalable, photonic approach to multiplex analysis with single virus sensitivity.

19 ng multifunctional multimodal LSPR chips for multiplexed analysis of different substances reaching ve

20 tion, and characterization of a platform for multiplexed analysis of disease-specific DNA sequences t

21 dispersion, individual layer treatment, and multiplex analytical assays.

22 nteractions to be quantitatively sensed in a multiplex and label-free fashion by means of diffraction

23 Here we demonstrate multiplex and simultaneous detection of four different r

24 We investigate the topology of the resulting multiplex and then proceed to evaluate single layers and

25 Voltage signals are filtered, amplified, multiplexed and digitized on the base, allowing the dire

26 l devices will be inherently well suited for multiplexed and parallel detection.

27 Here the authors demonstrate multiplexing and demultiplexing of data streams in the t

28 ernative to FISH as they are compatible with multiplexing and diagnostic workflows.

29 ial modes - a critical task for spatial-mode multiplexing and quantum communication - basis-specific

30 Multiplexing and simultaneous detection was achieved thr

31 y can offer in integration, miniaturization, multiplexing, and real-time label-free detection.

32 We report on a novel, highly-multiplexed approach to facilitate analysis of clinicall

33 Here we describe a GWAS using a highly multiplexed aptamer-based affinity proteomics platform.

34 p to 80 assays in parallel using a pneumatic multiplexing architecture.

35 Moreover, our gate design can be readily multiplexed as demonstrated by simultaneous small molecu

36 breast cancer (MBC) using a new quantitative multiplex assay (cMethDNA).

37 The high-throughput multiplex assay allowed us to simultaneously measure Fcg

38 The BD Max CT/GC/TV (MAX) assay is a true multiplex assay for simultaneous detection of chlamydia

39 We developed an ELISA and multiplex assay to model the cross-linking of Fcgamma re

40 was performed by using flow cytometry and a multiplex assay with bronchoalveolar lavage (BAL) specim

41 d by using immunohistochemistry, the Luminex Multiplex assay, ELISA, PCR, and immunoblotting and link

42 easured using quantitative real time PCR and multiplex assay.

43 ues for individual peptide substrates in the multiplex assay.

44 Here, we used a multiplexed assay for kinase specificity (MAKS) to ident

45 The multiplexed assay was performed approximately within 10m

46 Here, we discuss how multiplex assays of variant effect (MAVEs) can be used t

47 response to that of the MeWo cell line using multiplex assays.

48 ty, real-time polymerase chain reaction, and multiplex assays.

49 ation and implementation of robust and large multiplexed assays.

50 The pools are built via multiplexed assembly and sequenced using next-generation

51 trate the feasibility of large-scale aptamer multiplexing at a level that has not previously been rep

52 s with unique barcode sequences, followed by multiplexed barcode sequencing to identify yeast toxicit

53 IL-2, IL-6, and IL-8-were determined using a multiplex bead immunoassay.

54 e analysed for 47 inflammatory markers using multiplex bead technology.

55 ioimaging, in addition to their security and multiplex bioassay application.

56 Multiplexed bioluminescence resonance energy transfer (B

57 ldren) and DNA methylation (2,173), targeted multiplex biomarker (1,427), and transcriptomic (723) st

58 em can be easily constructed and applied for multiplex biomarker detection, making the device an exce

59 Multiplex biomarker enrichment is accomplished by adding

60 his, we have developed a magnetic bead-based multiplex biomarker enrichment strategy that combines me

61 components, we present fluorescently indexed multiplexed biomimetic membrane assays amenable to high-

62 We build fluorescently multiplexed biomimetic membrane assays by using varying

63 t signalling enzymes in a single assay using multiplex biosensing provides a multidimensional workspa

64 The multiplex cadmium biosensors were responsive to cadmium

65 Multiplexing capabilities for simultaneous quantificatio

66 ing due to its sensitivity, selectivity, and multiplexing capabilities.

67 labeling because of their photostability and multiplexing capabilities.

68 Leveraging the multiplex capability of the Cpf1 platform, we demonstrat

69 The multiplexing capability of LC-MS combined with a standar

70 using barcoded probes which has large-scale multiplexing capability.

71 ing payloads, yielding improved sensitivity, multiplexing capacity, and modularity of design.

72 Analysis of multiplex CARS images can distinguish between molecular

73 Using a multiplexed cell culture system, we find that switching

74 Here, we present multiplexed cell-based sensors to simultaneously quantif

75 regeneration of up to 16 wavelength-division-multiplexing channels by one device.

76 In processing multiple wavelength-division-multiplexing channels, large cross-phase modulation and

77 e use scanning electron microscopy (SEM) and multiplex coherent anti-Stokes Raman scattering (CARS) i

78 mated and establishes a general strategy for multiplex combinatorial genome engineering in eukaryotes

79 ffected by spurious signals inherent to this multiplexing concept.

80 and analyze thousands of individual cells in multiplexed conditions, our platform incorporates arrays

81 Arthrogryposis multiplex congenita (AMC) is a developmental condition c

82 ed, independently light-controlled pairs for multiplexed control of receptor populations.

83 We also provide a webtool to design multiplex CREATE libraries.

84 gonal channels, offering a unique ability to multiplex data transmission within a single acoustic bea

85 In the developmental cohort, a multiplex decision algorithm was constructed using urine

86 s also establish these Ln(III)-complexes for multiplex detection beyond the available two-color syste

87 d, sensitive, label-free LC-MS/MS method for multiplex detection of five allergenic ingredients in a

88 e adaptation to include other mycotoxins for multiplex detection.

89 are affordable, integrated, fast, capable of multiplexed detection, and offer high selectivity for tr

90 aches are parallelizable and compatible with multiplexed detection; to date, however, they have remai

91 resent an automated monolithic chip with 128 multiplexed deterministic lateral displacement devices c

92 Development of rapid and multiplexed diagnostic tools is a top priority to addres

93 Current multiplexed diagnostics for Zika, dengue, and chikunguny

94 olution algorithm to retrieve both spatially multiplexed discrete data and continuous volumetric data

95 Here we report an experiment that realizes a multiplexed DLCZ-type quantum memory with 225 individual

96 We performed multiplexed droplet digital polymerase chain reaction to

97 We applied our analysis algorithm to multiplexed droplet-based digital PCR data sets in both

98 silicon nanowire (SiNW) array measured by a multiplexed electrical readout.

99 tion MBs with 8-electrode arrays enabled the multiplexed electrochemical detection of AZAs.

100 Multiplex ELISA measured BAL cytokines.

101 We first demonstrated that multiplex embryo transfer efficiently produced multiple

102 offers a straightforward approach to achieve multiplexed external switching of polymer chain growth u

103 ting with multiple printing heads and, thus, multiplexed fabrication.

104 iduals with severe ID (35 of 77 [45.5%]), in multiplex families (42 of 107 [39.3%]), in patients with

105 nts co-segregating with TD phenotypes within multiplex families have been identified.

106 Fathers in multiplex families have marginally greater similarity (P

107 and whole-exome sequencing in four unrelated multiplex families presenting with severe AMC, we identi

108 l glucose transporter, in two consanguineous multiplex families with moderate to severe ID, epilepsy,

109 Using exome sequencing in a multiplex family and three simplex case subjects with an

110 on in PNKD was co-segregated with TD in this multiplex family.

111 out of nine members in a three-generation TD multiplex family.

112 tory landscape of a 3'UTR, and apply it in a multiplex fashion to analyse combinatorial interactions

113 Using a fluorescence-based multiplex flow cytometric host cell reactivation assay t

114 as compared to the Bioplex 2200 Syphilis IgG multiplex flow immunoassay.

115 simultaneous assay by Western blotting using multiplex fluorescence imaging with specific antibodies

116 Single-cell sequencing and multiplex fluorescence in situ hybridization analyses ma

117 gs of precisely known infection status and a multiplex fluorescent microbead-based immunoassay and/or

118 listic method for detection of synapses from multiplex FM (muxFM) image data, and evaluate this metho

119 e and characterize the performance of an OAM-multiplexed, free-space optical (FSO) communications lin

120 a technique for quantitative analysis using multiplexing gas chromatography (mpGC) for continuous an

121 tronic tRNA-gRNA gene (PTG) strategy enables multiplex gene editing in the family of closely related

122 raightforward approach to study quantitative multiplex gene expression in numerous biological systems

123 logy with broad applications that range from multiplexed gene expression analysis to the sensitive de

124 In summary, this study shows how multiplex genome editing can be used to rapidly dissect

125 ns that optimize a complex phenotype through multiplex genome engineering and predictive modeling.

126 We describe a multiplex genome engineering technology in Saccharomyces

127 Here we report an automated platform for multiplex genome-scale engineering in Saccharomyces cere

128 d increases exponentially with the number of multiplexed gRNAs and that, with four multiplexed gRNAs,

129 ber of multiplexed gRNAs and that, with four multiplexed gRNAs, a mosquito species could potentially

130 me, and we show that with the WDV replicons, multiplexed GT within the same wheat cell can be achieve

131 Here, we describe a novel multiplexed, high-throughput, and sensitive peptide-base

132 We describe a method to multiplex homologous recombination (HR) in human hematop

133 We recently developed fluorescence-based multiplexed host cell reactivation (FM-HCR) assays to me

134 ent colored objects: while all three patches multiplex hue and shape information, shape-invariant hue

135 Multiplexed HyCCAPP provides a useful strategy for the i

136 Multiplexed HyCCAPP was applied to four genes (25S rDNA,

137 A rapid, sensitive and multiplexed imaging surface plasmon resonance (iSPR) bio

138 We did an unbiased, multiplex immunoassay assessment of 123 biomarkers.

139 PsychArray and the expression levels of 190 multiplex immunoassay profiled serum proteins in 149 sch

140 Six cytokines/chemokines were quantified by multiplex immunoassay, alveolar bone volume was quantifi

141 mined by means of flow cytometry, ELISA, and multiplex immunoassay.

142 er substudy, biomarkers were quantified by a multiplex immunoassay.

143 ammatory cytokines/chemokines measured using multiplex immunoassays.

144 We used multiplexed immunoassays to determine serum cytokine con

145 pernatants were assessed by suspension array multiplexed immunoassays.

146 Our goal was to validate multiplex immunofluorescence (mIF) panels to apply to fo

147 We used multiplex immunofluorescence and digital image analysis

148 THRIVE was designed with highly multiplexed immunofluorescence images in mind, and, by p

149 Multiplexed immunofluorescence imaging of formalin-fixed

150 However, multiplex immunohistochemistry with a maximized number o

151 Here, we used multiplexed in situ hybridization and single-cell RNA-Se

152 Using single-cell RNA-Seq and multiplexed in situ hybridization, we show here that a s

153 Extensive multiplexing in combination with next-generation sequenc

154 architecture in which guide RNAs (gRNAs) are multiplexed, increasing the effective homing rate and de

155 Using the Proseek Multiplex Inflammation assay, we measured in patients th

156 dy in flies reveals novel neurons capable of multiplexing information of a visual scene and encoding

157 t protein kinases via capture on immobilized multiplexed inhibitor beads with subsequent proteolytic

158 ng, and stratification of cancer variants by multiplexed interaction profiling.

159 In this way, joint spectral and spatial multiplexing is implemented that encodes both spatial an

160 detection of multiple pathogens and samples (multiplexing) is one of the key requirements for diagnos

161 action monitoring kits and an antibody-based multiplexing kit were used to compare the apolipoprotein

162 od was evaluated on multi-spectral images of multiplex-labeled pancreatic ductal adenocarcinoma (PDAC

163 n in early learners: while initially all the multiplex layers contribute to word learning, after abou

164 Finally, by the use of multiplexed layers of electronic circuits, we study the

165 d isoform-specific peptides was monitored by multiplex LC-MS/MS through the parallel reaction monitor

166 Multiplex ligation-dependent probe amplification (MLPA)

167 le cancer cells, exploiting a combination of multiplex ligation-dependent probe amplification (MLPA)

168 ed genetic analyses by direct sequencing and multiplex ligation-dependent probe amplification and ret

169 uantification methods based on principles of multiplex ligation-dependent probe amplification and tar

170 Viruses and bacteria were identified by multiplex ligation-dependent probe amplification assay a

171 gene cluster were studied in a FCGR-specific multiplex ligation-dependent probe amplification assay.

172 by conventional mutation screening underwent multiplex ligation-dependent probe amplification.

173 e we introduce an approach to achieve highly multiplexed live recording via correlative CRISPR imagin

174 imodal plasmonic nanostructures suitable for multiplexed localized surface plasmon resonance (LSPR) b

175 for single-layer networks extracted from the multiplex may have serious consequences in the character

176 ational scanning is a widely used method for multiplex measurement of functional consequences of prot

177 translocation reporters (KTRs), which enable multiplexed measurements of the dynamics of kinase activ

178 The features of this multiplexed mechanism help to explain how complex connec

179 ere, we present a scalable scheme for highly multiplexed mesh electronics probes to bridge the gap be

180 e broadband, flexible, conformable, helicity multiplexed metasurface holograms operating in the visib

181 ver, the development of a rapid, simple, and multiplex method for the simultaneous measurement of the

182 ediators were quantified using comprehensive multiplex microbead-based immunoassays for 46 immune med

183 In this study, a multiplexed microscopy characterization is developed to

184 This multiplexed, miniaturized sample preparation microdevice

185 Here, we developed a sensitive and accurate multiplex miRNA profiling method using modified isotherm

186 t of RARb2, ATM, MGMT and GSTP1 promoters in multiplexed MS-NaME reactions (177-plex) using dilutions

187 The Multiplex (Mx) sensor here studied provides two anthocya

188 ll reagents needed for sample processing and multiplex nested PCR.

189 tion of the optimal percolation problem on a multiplex network with solutions valid for single-layer

190 the way for the systematic study of temporal multiplex networks and we anticipate it will be of inter

191 However, its generalization to multiplex networks has not yet been considered.

192 ions between layers exhibited by real social multiplex networks.

193 proved accuracy, open up the possibility for multiplexed NIR-fluorescence enhancement microarrays, fo

194 mit of FTN non-orthogonal frequency-division multiplexing (NOFDM) signal is first demonstrated in thi

195 ection, including both antigen detection and multiplex nucleic acid amplification techniques, is beco

196 T) is a simple, sample-to-answer, on-demand, multiplex, nucleic acid amplification test for syndromic

197 ork is simple and effective for point-of-use multiplexing of immunoassays and was applied in this wor

198 dvances in speed, sensitivity, and extent of multiplexing of molecular pathogen detection assays are

199 Multiplexing of several guide RNAs does not increase the

200 Multiplexing of targeted methods based on capture and de

201 ay for superconducting qubit processors with multiplexed on-chip signal processing and readout.Nonrec

202 This system allows functional mapping and multiplex optimization on a genome scale for diverse phe

203 etic screens to be carried out at scale in a multiplexed or arrayed format.

204 cers coupled to TALE drivers, we demonstrate multiplexed orthogonal activation of several transgenes

205 This multiplex panel allows for simultaneous quantification o

206 imary Ab concentrations and order within the multiplex panel, which are of major importance for the s

207 Firstly, multiplex PCR analysis indicated that the novel strain b

208 ortrait Staph ID/R blood culture panel (BCP) multiplex PCR assay (Great Basin Scientific, Salt Lake C

209 Finally, a novel multiplex PCR assay, based on random amplified polymorph

210 New multiplex PCR assays were developed for mating-type dete

211 , Wageningen, the Netherlands) and published multiplex PCR assays.

212 MPD can successfully design multiplex PCR experiments suitable for next-generation s

213 Our method relies on multiplex PCR for targeted enrichment of viral genomes f

214 udy proposes an authentication protocol with multiplex PCR for three species of snappers (Lutjanus pu

215 Multiplex PCR identified T. nativa from the bear meat, a

216 59 months, we compared organism detection by multiplex PCR in IS and nasopharyngeal/oropharyngeal (NP

217 oftware package that automates the design of multiplex PCR primers for next-generation sequencing.

218 A multiplex PCR to differentiate S. hyicus, S. agnetis, an

219 TB-DzT combines a multiplex PCR with single nucleotide polymorphism (SNP)

220 Here, we designed and validated a novel multiplex PCR-based assay for STc648 that took advantage

221 Thus, this novel multiplex PCR-based assay should enable any laboratory e

222 d using an innovative strategy consisting of multiplexing PCR, targeted sequencing and computational

223 Simple, multiplexed, PCR-based barcoding of DNA for sensitive mu

224 signature design from genome-wide datasets, multiplex-PCR and detection by single-base extension and

225 nal quality and capacity for extensive probe multiplexing permits quantitative analysis of distinct,

226 lanar Fabry-Perot micro-cavity via angularly multiplexed phase-matching that exploits a bio-inspired

227 e assays are suitable for the development of multiplex point-of-care neglected diseases sensing appli

228 otyping, named as AmpSeq-SSR, which combines multiplexing polymerase chain reaction (PCR), targeted d

229 hods, and enrich cell populations containing multiplexed precise edits up to 42-fold.

230 Progress in technologies that enable highly multiplexed profiling of markers within a single cell pr

231 proteomics with the capacity for archivable, multiplexed protein analysis offers a unique, complement

232 Using a systematic multiplexed proteomics approach to quantify 1300 cell s

233 Here we use isobaric-labeling multiplexed proteomics to analyze protein co-regulation

234 g isotopic labeling, chemical enrichment and multiplexed proteomics was developed to simultaneously q

235 mammalian RNA and forms the basis of our new multiplexed protocol for high-throughput, selective RNA-

236 eactive tandem mass tags (aminoxyTMT) enable multiplexed quantification of glycans through comparison

237 rious biological samples, and enables highly multiplexed quantification of peptides at the MS(1) leve

238 improve electrophoretic migration and enable multiplexed quantitation by tandem MS.

239 secretory protein, which we identified via a multiplex quantitative proteomics screen of acutely inju

240 of antimicrobial peptides was measured using multiplex quantitative real time PCR.

241 ies and across imaging platforms, as well as multiplexed quantitative information on the molecular id

242 ng density gradient ultracentrifugation with multiplexed quantitative proteomics mass spectrometry, a

243 ce (CMR) and tissue samples were analyzed by multiplexed quantitative proteomics.

244 Experimental realization of a multiplexed quantum memory with many individually access

245 and quantum network, it is required to have multiplexed quantum memory with many memory cells.

246 led nasal and throat swabs were tested using multiplex real-time PCR for 33 respiratory pathogens (FT

247 This multiplex real-time PCR, based on the dual-labeled probe

248 , isobaric labeling at the peptide level for multiplexed relative quantification and ultra-high-perfo

249 within CA1 neuronal networks as independent, multiplexed representations of space and time.

250 sion probes (cDNA-smMIPs) that enable highly multiplexed resequencing of cDNA target regions of appro

251 e demonstrate that 7C1 nano-encapsulation of multiplexed RNAi is a viable BTIC-targeting strategy whe

252 ughputs or protein libraries compatible with multiplexed screening platforms.

253 , thereby opening the way to the creation of multiplexed sensor systems.

254 A multiplexed separation platform based on multisegment in

255 es, A11/D11 and A12/D12, were used to assess multiplex sequencing approaches for completeness and sca

256 M. tuberculosis antigens using a field-based multiplexed serological assay and a 132-antigen bead-bas

257 etaPV IgG seroresponses were determined with multiplex serology.

258 In addition, we have developed a multiplexed sgRNA expression strategy that promotes the

259 Multiplexing sgRNAs enabled targeting methylation to mul

260 T. coronopifolia, genotyped F2 plants using multiplexed shotgun genotyping (MSG), and located MSG ma

261 This strain was found amenable to multiplex SILAC by case study of responses to oxidative

262 combination of lipid bilayer nanodiscs and a multiplexed silicon photonic analysis technology enables

263 address this problem, we developed a highly multiplexed single-cell DNA sequencing approach to trace

264 , and later read out in single cells through multiplexed single-molecule RNA fluorescence hybridizati

265 notypes with phenotypes, are well suited for multiplexed single-molecule screening of protein librari

266 Here, we scale up multiplexed smFISH to the transcriptome level and profil

267 egative results were analyzed via the highly multiplexed SOMAscan proteomic assay.

268 ker discovery was performed using the highly multiplexed SOMAscan((R)) proteomic assay, a set of 19 c

269 mber in thermoplastic material and performed multiplexed SP-PCR directly on top of the SAF microlens

270 velopment times, cross-reactivity preventing multiplexing, specificity issues, and incomplete sensiti

271 This study provides a genome editing-based multiplex strategy for direct functional interrogation o

272 e individual murine B1a cells using a custom multiplexing strategy.

273 oceed to evaluate single layers and the full multiplex structure on their ability to predict empirica

274 algorithm for automated data analysis and a multiplexing system promoting practicality and translata

275 Multiplexed tag-encoded sequencing of DNA from the sampl

276 The multiplexed Tandem Mass Tag based proteomics (TMT-MS3) w

277 In addition, FRES showed a multiplex targeting ability even on a subcentimeter-size

278 FRES demonstrated fast signal detection and multiplex targeting ability using fluorescence and Raman

279 We then demonstrated the powerful multiplex targeting capacity of CRISPR/Cas9.

280 have emerged but do not robustly account for multiplexed targets, low target concentration, and assay

281 of affected and unaffected individuals in a multiplex TD family to discover genes involved in the TD

282 ion (GP) controls (N=428) using a bead-based multiplex technology.

283 By multiplexing this approach, we investigate the unique tr

284 ery simple experimental system that could be multiplexed to greater scales.

285 monitor peptide surrogates, which are easily multiplexed to target many peptides in a single assay.

286 We find that the multiplex topology is an important proxy of the cognitiv

287 Moreover, we developed a multiplex transcription activator-like effector activati

288 idate disease genes for tooth agenesis in 10 multiplex Turkish families.

289 iana NbAGO1 paralogs with one sgRNA and also multiplexed two sgRNAs using a single TRBO construct, re

290 A multiplex ultrasensitive electrochemiluminescence (ECL)

291 The approach can be multiplexed up to 10-plex using tandem mass tags (TMT) r

292 We present here a multiplexed version of HyCCAPP.

293 we call "track first and identify later" for multiplexed visualization of chromosome dynamics by comb

294 roducing targeted combinations of changes in multiplex we generate rich genotypic and phenotypic dive

295 cytokines and other markers were measured in multiplex with a commercially-available Luminex-based sy

296 The method was multiplexed with the analysis of 12 Gb3 isoforms/analogu

297 herefore, the UCP-LFA platform, which allows multiplexing with differential biomarkers, offers more c

298 comes close to this ideal due to the ease of multiplexing, without the need for expensive labelling m

299 We present a two-dimensional multiplexing workflow that utilizes synthetic peptides f

300 Here, we present a massively multiplexed yeast two-hybrid method, CrY2H-seq, which us