ライフサイエンスコーパス: murein hydrolase

1 OmpR; the second contained mipA, encoding a murein hydrolase.

2 A and SarA both being negative regulators of murein hydrolases.

3 ation, and purified SspA cleaves Atl-derived murein hydrolases.

4 Zymographic and quantitative analyses of murein hydrolase activity also revealed that disruption

5 nd lrgAB operons have been shown to regulate murein hydrolase activity and affect antibiotic toleranc

6 ous operons that have been shown to regulate murein hydrolase activity and affect sensitivity to peni

7 The cid operon enhances murein hydrolase activity and antibiotic sensitivity, wh

8 The cid gene products enhance murein hydrolase activity and antibiotic tolerance where

9 d demonstrate that these operons, as well as murein hydrolase activity and antibiotic tolerance, are

10 operons have previously been shown to affect murein hydrolase activity and antibiotic tolerance.

11 ytSR two-component regulatory system affects murein hydrolase activity and autolysis.

12 Due to the growing link between murein hydrolase activity and biofilm maturation, autoly

13 hown to play a key role in the regulation of murein hydrolase activity and cell death in a manner tho

14 e wild-type gene restored expression of this murein hydrolase activity and cell separation levels to

15 of the B. anthracis cid and lrg homologues, murein hydrolase activity and cell viability in stationa

16 Staphylococcus aureus lrgAB operon inhibits murein hydrolase activity and decreases sensitivity to p

17 ence of 35 mM glucose and that this enhances murein hydrolase activity and decreases tolerance to van

18 was recently shown to inhibit extracellular murein hydrolase activity and increase tolerance to peni

19 om that of lrgAB by increasing extracellular murein hydrolase activity and increasing sensitivity to

20 Cid proteins enhance murein hydrolase activity and penicillin sensitivity, wh

21 ologous proteins that regulate extracellular murein hydrolase activity and penicillin tolerance in a

22 teins that are involved in the regulation of murein hydrolase activity and penicillin tolerance.

23 -regulated operon, designated lrgAB, affects murein hydrolase activity and penicillin tolerance.

24 ysis in S. aureus by affecting the intrinsic murein hydrolase activity associated with the cell.

25 was also shown to have a positive impact on murein hydrolase activity but a negligible effect on sen

26 er resistance to lysis is due to a defect in murein hydrolase activity by using a zymogram analysis.

27 cidA gene results in decreased extracellular murein hydrolase activity compared to that of S. aureus

28 rgAB mutant produced increased extracellular murein hydrolase activity compared to that of the wild-t

29 sarV gene results in decreased extracellular murein hydrolase activity compared to that of wild-type

30 lts in significantly decreased extracellular murein hydrolase activity compared with that of the pare

31 Penicillin-induced killing and murein hydrolase activity in Staphylococcus aureus are d

32 r, neither mutation had a dramatic effect on murein hydrolase activity or autolysis.

33 , respectively, that function to control the murein hydrolase activity produced by the bacteria.

34 n of cidABC expression resulted in increased murein hydrolase activity produced by these cells.

35 increased autolysis and an altered level of murein hydrolase activity produced compared with the par

36 tracellular protease levels and altering the murein hydrolase activity profile.

37 Zymographic analysis of murein hydrolase activity revealed that inactivation of

38 Zymographic and quantitative analyses of murein hydrolase activity revealed that mutation of the

39 Zymographic and quantitative analysis of murein hydrolase activity revealed that the lrgAB mutant

40 Rv2719c protein exhibited mycobacterial murein hydrolase activity that was localized to the N-te

41 , as well as its counterpart EA1, to exhibit murein hydrolase activity was confirmed by cloning their

42 The effect of glucose on murein hydrolase activity was not observed in the cidA m

43 ncode a novel regulatory system that affects murein hydrolase activity, stationary-phase survival and

44 ion of the cid and lrg operons, which affect murein hydrolase activity, stationary-phase survival, an

45 n operon that encodes a positive effector of murein hydrolase activity, the upregulation of cidABC ex

46 Streptococcus mutans surface protein affects murein hydrolase activity.

47 enicillin, attributable in part to increased murein hydrolase activity.

48 on has a positive influence on extracellular murein hydrolase activity.

49 nes confer negative control on extracellular murein hydrolase activity.

50 ypothesized to be involved in the control of murein hydrolase activity.

51 g of S. aureus involves a novel regulator of murein hydrolase activity.

52 teins while lrgB may encode a protein having murein hydrolase activity.

53 Interestingly, the predominant murein hydrolase affected was an 85 kDa protein that was

54 Finally, two murein hydrolases, AmiC and EnvC, have been shown to loc

55 processes: increased expression of the AtlA murein hydrolase and decreased expression of wall-teicho

56 PCL is dependent upon the AtlA murein hydrolase and is regulated, in part, by the SrrAB

57 ere that Esp cleaves autolysin (Atl)-derived murein hydrolases and prevents staphylococcal release of

58 Murein hydrolases appear to be widespread in the virions

59 nvolved in the modification of substrates of murein hydrolases as well as in the regulation of expres

60 forms and perturb the deposition of the BslO murein hydrolase at cell division septa.

61 likely due to its inability to deposit BslO murein hydrolase at divisional septa.

62 A model is proposed whereby murein hydrolases cleave the anchor structure of release

63 LytN, a cross-wall murein hydrolase, contributes to the release of SpA by r

64 s of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin

65 effects on autolysis, in part, by modulating murein hydrolase expression and/or activity.

66 In this report, we studied a murein hydrolase from the streptococcal bacteriophage C(

67 We show that bacteriophage N4 encodes a murein hydrolase (gp61) that is essential for N4 plaque-

68 drolase/peptidase) domain found in bacterial murein hydrolases; however, direct links between steps i

69 lular Listeria monocytogenes secretes p60, a murein hydrolase, into the host cell cytosol, where it i

70 The regulation of murein hydrolases is a critical aspect of peptidoglycan

71 One such YSIRK-containing protein is the murein hydrolase LytN.

72 vidence for the enzymatic flexibility of the murein hydrolase NamA and demonstrate that bacterial sep

73 r to this N-terminal domain are found in the murein hydrolases of staphylococcal phages but not in th

74 Murein hydrolases of staphylococcal phages phi11, 80alph

75 nhibiting a putative holin from transporting murein hydrolases out of the cell.

76 217-225, which is derived from the bacterial murein hydrolase p60 and presented by the H-2Kd MHC clas

77 Lysins are murein hydrolases produced by bacteriophage that act on

78 y establish the existence of the cid and lrg murein hydrolase regulatory network in B. anthracis, but

79 from the bacterial surface by treatment with murein hydrolase, suggesting that the pilus fibres may b

80 ies are consistent with a role for PcsB as a murein hydrolase that balances the extent of cell wall s

81 studies show that lysin represents a unique murein hydrolase that has a rapid lethal effect both in

82 onger restricted the deposition of LysM-type murein hydrolases to cell division sites, which was asso

83 hat the LysM domains of Sle1 and LytN direct murein hydrolases to the staphylococcal envelope in the

84 of BslO, the S-layer-associated protein, and murein hydrolase, which cleaves septal peptidoglycan to

85 lation of expression and/or activity of some murein hydrolases, which, in turn, may play important ro

86 us aureus, a spherical microbe, secretes two murein hydrolases with LysM domains, Sle1 and LytN.