ライフサイエンスコーパス: murine cytomegalovirus

1 rpesvirus 1, guinea pig cytomegalovirus, and murine cytomegalovirus.

2 of retinitis after supraciliary injection of murine cytomegalovirus.

3 plify both inflammasome and IFN-I to control murine cytomegalovirus.

4 emerged as a host defence mechanism against murine cytomegalovirus.

5 rom herpes simplex virus type 1 and M48 from murine cytomegalovirus.

6 not DR3 dependent after viral challenge with murine cytomegalovirus.

7 also blocked duplication and deletion of the murine cytomegalovirus 30-bp terminal repeat at the ecto

8 Here we describe a murine cytomegalovirus 7.2-kb ortholog of the human cyto

9 Murine cytomegalovirus (9 x 10(2) plaque forming units [

10 For murine cytomegalovirus and Epstein-Barr virus, chosen as

11 previous proposals for mutations in UL104 of murine cytomegalovirus and HCMV strains resistant to BAY

12 also induced acute allograft rejection, but murine cytomegalovirus and vaccinia virus (VV) did not.

13 to five heterologous viruses (LCMV, PV, VV, murine cytomegalovirus, and vesicular stomatitis virus)

14 h differential effects of NK subsets on anti-murine cytomegalovirus (anti-MCMV) responses after synge

15 as been modeled in BALB/c mice infected with murine cytomegalovirus by the supraciliary route.

16 Murine cytomegalovirus carries a CC (beta) chemokine hom

17 The murine cytomegalovirus CC chemokine homolog MCK-2 (m131-

18 oduction is critical for host defense during murine cytomegalovirus challenge.

19 og gene giving rise to two related proteins, murine cytomegalovirus chemokine 1 and 2 (MCK-1 and MCK-

20 Murine cytomegalovirus (CMV) and herpes simplex virus (H

21 ted mice after supraciliary inoculation with murine cytomegalovirus compared with less intense DNA la

22 (d)/Fc gamma1 molecules were loaded with the murine cytomegalovirus-derived peptide and other L(d)-sp

23 s the most effective agent against human and murine cytomegalovirus (EC(50) 0.25-1.1 microM).

24 Systemic infection with murine cytomegalovirus elicited a significant increase i

25 Here, we report that the murine cytomegalovirus-encoded CC chemokine, MCK2, enhan

26 Murine cytomegalovirus encodes a secreted, pro-inflammat

27 The M78 protein of murine cytomegalovirus exhibits sequence features of a G

28 Murine cytomegalovirus expresses a 7.2-kb-long noncoding

29 rapid phenotypic screening, we identified a murine cytomegalovirus gene governing endothelial cell t

30 by inserting ectopic cleavage sites into the murine cytomegalovirus genome and assessing their abilit

31 e ectopic cleavage sites engineered into the murine cytomegalovirus genome mediated formation of pac2

32 Within the murine cytomegalovirus genome, m41, m40, and m39 form a

33 iased approach to identify such genes in the murine cytomegalovirus genome.

34 olog of vMIA, m38.5, which was identified in murine cytomegalovirus, has been shown to localize to mi

35 5b was the most effective against human and murine cytomegalovirus (HCMV and MCMV) with EC(50) = 0.2

36 lar or submicromolar range against human and murine cytomegalovirus (HCMV and MCMV), Epstein-Barr vir

37 Both human and murine cytomegaloviruses (HCMV and MCMV) down-regulate e

38 the recently published NMR structure of the murine cytomegalovirus homolog pM50 but reveals a consid

39 ine gammaherpesvirus 68) or betaherpesvirus (murine cytomegalovirus), HS is rapidly upregulated at th

40 49H, is critically involved in resistance to murine cytomegalovirus in vivo.

41 In transfected and murine cytomegalovirus-infected cells, m02, m04, m05, m0

42 cells protects mice from retinitis caused by murine cytomegalovirus infection after supraciliary inoc

43 cells (DC), and natural killer (NK) cells to murine cytomegalovirus infection and found distinct func

44 l responses and plasma cell expansion during murine cytomegalovirus infection and modestly restrains

45 pattern of regulation was found in vivo with murine cytomegalovirus infection as a physiologic model

46 In mice, systemic murine cytomegalovirus infection decreased serum erythro

47 ed at the transcriptional level during acute murine cytomegalovirus infection or after repetitive pol

48 production by activated NK cells in an acute murine cytomegalovirus infection was significantly reduc

49 that in the setting of a short-term (4-day) murine cytomegalovirus infection, terminally differentia

50 phase of viral-induced proliferation during murine cytomegalovirus infection.

51 premature death of endothelial cells during murine cytomegalovirus infection.

52 display long-term, memory-like responses to murine cytomegalovirus infection.

53 Lymphocytic choriomeningitis virus and murine cytomegalovirus infections also induced this traf

54 During murine cytomegalovirus infections known to target spleen

55 induced liver pathology was evaluated during murine cytomegalovirus infections of mice.

56 during lymphocytic choriomeningitis virus or murine cytomegalovirus infections resulted in profound s

57 The m144 glycoprotein, expressed by murine cytomegalovirus, is thought to be an MHC-I homolo

58 The murine cytomegalovirus m02 gene family encodes putative

59 Murine cytomegalovirus m38.5, whose position in the vira

60 The murine cytomegalovirus m41 product is the first example

61 The murine cytomegalovirus M45 protein interacts with recept

62 structure of the cysteine protease domain of murine cytomegalovirus M48 (M48(USP)) in a complex with

63 tTS(Kid) repressor under the control of the murine cytomegalovirus (mCMV) (HC-Ad-mTetON-beta-Gal) or

64 d without cGvHD received a nonlethal dose of murine cytomegalovirus (MCMV) +100 days after transplant

65 Three proteins encoded by murine cytomegalovirus (MCMV) -- gp34, encoded by m04 (m

66 Animals were infected with murine cytomegalovirus (MCMV) after birth at 2 days (P2)

67 Murine cytomegalovirus (MCMV) and human CMV (HCMV) share

68 e response to viral infections, particularly murine cytomegalovirus (MCMV) and human herpesviruses.

69 his report, we studied the interplay between murine cytomegalovirus (MCMV) and human monocyte-derived

70 tions with two different persistent viruses, murine cytomegalovirus (MCMV) and lymphocytic choriomeni

71 were examined in C57BL/6 mice infected with murine cytomegalovirus (MCMV) and other viruses, includi

72 ) as major producers of the cytokines during murine cytomegalovirus (MCMV) but not lymphocytic chorio

73 ell- depleted BALB/c mice were injected with murine cytomegalovirus (MCMV) by supraciliary injection.

74 Here, we defined the genetic stability of murine cytomegalovirus (MCMV) by whole-genome sequencing

75 to target the overlapping mRNA region of two murine cytomegalovirus (MCMV) capsid proteins essential

76 FasL-deficient B6-gld/gld mice infected with murine cytomegalovirus (MCMV) cleared the virus from the

77 mRNA of the late kinetic class expressed by murine cytomegalovirus (MCMV) contains an open reading f

78 e that endothelial cells are a major site of murine cytomegalovirus (MCMV) DNA in latently infected a

79 A gene (HJ1) present in murine cytomegalovirus (MCMV) encodes an open reading fr

80 o evade detection by the host immune system, murine cytomegalovirus (MCMV) encodes three proteins tha

81 By contrast, systemic infection with a murine cytomegalovirus (MCMV) engineered to express HEL

82 xpressed endogenously during infections with murine cytomegalovirus (MCMV) enhanced early IL-12 and I

83 We used recombinant murine cytomegalovirus (mCMV) expressing either green fl

84 mechanisms that permit prolonged shedding of murine cytomegalovirus (MCMV) from the salivary gland, t

85 Murine cytomegalovirus (MCMV) gene products dispensable

86 a pool of 13 plasmid DNAs (pDNAs) expressing murine cytomegalovirus (MCMV) genes followed by formalin

87 ice with plasmid DNAs (pDNAs) expressing the murine cytomegalovirus (MCMV) genes IE1-pp89 and M84 pro

88 he species specificity of cytomegaloviruses, murine cytomegalovirus (MCMV) has been used as a model f

89 vaccination of BALB/c mice with DNA encoding murine cytomegalovirus (MCMV) IE1 or M84, a similar leve

90 oxic T-lymphocyte (CTL) response against the murine cytomegalovirus (MCMV) immediate-early gene 1 (IE

91 The murine cytomegalovirus (MCMV) immediate-early gene 1 (IE

92 at in vitro stimulation of spleen cells from murine cytomegalovirus (MCMV) immune mice with MCMV-infe

93 Efficient replication of murine cytomegalovirus (MCMV) in macrophages is a prereq

94 Astrocytes are the first cells infected by murine cytomegalovirus (MCMV) in primary cultures of bra

95 tion of apolipoprotein E-deficient mice with murine cytomegalovirus (MCMV) increases serum levels of

96 Early infection with murine cytomegalovirus (MCMV) induces circulating levels

97 Infection of mouse cells with murine cytomegalovirus (MCMV) induces the rapid down-reg

98 for innate regulation of the acute phase of murine cytomegalovirus (MCMV) infection and have been re

99 Murine cytomegalovirus (MCMV) infection and the TLR3 lig

100 e model was used to determine the pattern of murine cytomegalovirus (MCMV) infection and whether apop

101 plantation, 3 x 10(3) CLPs protected against murine cytomegalovirus (MCMV) infection at a level rough

102 ma (IFN-gamma) are required for clearance of murine cytomegalovirus (MCMV) infection from the salivar

103 oting antiviral defense in the liver against murine cytomegalovirus (MCMV) infection have been charac

104 Murine cytomegalovirus (MCMV) infection in the lungs of

105 s by which natural killer (NK) cells control murine cytomegalovirus (MCMV) infection in the spleens a

106 Macrophages play an important role in murine cytomegalovirus (MCMV) infection in vivo, both in

107 ckout (KO) mice produce more IFN-alpha after murine cytomegalovirus (mCMV) infection in vivo.

108 Having previously demonstrated that murine cytomegalovirus (MCMV) infection of apolipoprotei

109 Murine cytomegalovirus (MCMV) infection of mice induces

110 at retinal neurons are infected early during murine cytomegalovirus (MCMV) infection of the inner ret

111 IM)-dependent programmed necrosis induced by murine cytomegalovirus (MCMV) infection or death recepto

112 Murine cytomegalovirus (MCMV) infection severely impaire

113 y been demonstrated to be protective against murine cytomegalovirus (MCMV) infection, and we show her

114 r mTOR signaling events were observed during murine cytomegalovirus (MCMV) infection, and we utilized

115 In murine cytomegalovirus (MCMV) infection, pDC depletion r

116 s play a pivotal role in the pathogenesis of murine cytomegalovirus (MCMV) infection, providing funct

117 During persistent murine cytomegalovirus (MCMV) infection, the T cell resp

118 important early mediator of host immunity to murine cytomegalovirus (MCMV) infection.

119 y key roles in acute, persistent, and latent murine cytomegalovirus (MCMV) infection.

120 retinoids can alter the outcome of an acute murine cytomegalovirus (MCMV) infection.

121 role of interferon gamma (IFN-gamma) during murine cytomegalovirus (MCMV) infection.

122 ammaRs on brain-resident microglia following murine cytomegalovirus (MCMV) infection.

123 in significantly increased susceptibility to murine cytomegalovirus (MCMV) infection.

124 with Toll-like receptor-7 and -9 ligands, or murine cytomegalovirus (MCMV) infection.

125 cells are essential for the early control of murine cytomegalovirus (MCMV) infection.

126 ler (NK) cells mediate defense against early murine cytomegalovirus (MCMV) infections in liver.

127 nce during some virus infections--especially murine cytomegalovirus (MCMV) infections in mice and per

128 ic cytotoxic T lymphocytes (CTLs) and during murine cytomegalovirus (MCMV) infections of the livers o

129 ller (NK) cell inflammation in livers during murine cytomegalovirus (MCMV) infections, and NK cell-pr

130 ceptor confers in vivo genetic resistance to murine cytomegalovirus (MCMV) infections, but its ligand

131 iate downstream protective responses against murine cytomegalovirus (MCMV) infections.

132 Murine cytomegalovirus (MCMV) interferes with antigen pr

133 plantation of kidneys latently infected with murine cytomegalovirus (MCMV) into NOD.Cg-Prkdc(scid) IL

134 acute infection with the hepatotropic virus murine cytomegalovirus (MCMV) involves complex cytokine

135 st host immune responses the betaherpesvirus murine cytomegalovirus (MCMV) is able to establish lifel

136 revious studies showed that establishment of murine cytomegalovirus (MCMV) latency in vivo is associa

137 The protease domain of the murine cytomegalovirus (MCMV) M80 open reading frame was

138 have been identified in the closely related murine cytomegalovirus (MCMV) mouse model, revealing nov

139 We used a live attenuated murine cytomegalovirus (MCMV) mutant to analyze mechanis

140 We have recently generated a pool of murine cytomegalovirus (MCMV) mutants by using a Tn3-bas

141 We have recently generated a pool of murine cytomegalovirus (MCMV) mutants by using a Tn3-bas

142 We had previously constructed a pool of murine cytomegalovirus (MCMV) mutants that contained a T

143 A pool of murine cytomegalovirus (MCMV) mutants was generated by u

144 A pool of murine cytomegalovirus (MCMV) mutants was previously gen

145 enesis approach, we have generated a pool of murine cytomegalovirus (MCMV) mutants.

146 We report the specific collision of a single murine cytomegalovirus (MCMV) on a platinum ultramicroel

147 ort observations of stochastic collisions of murine cytomegalovirus (MCMV) on ultramicroelectrodes (U

148 binding of monosubstituted analogues of the murine cytomegalovirus (MCMV) pp89 168-176 and the tum-

149 NK cells were able to respond to a specific murine cytomegalovirus (MCMV) protein and that in the ab

150 al immunization with plasmids expressing the murine cytomegalovirus (MCMV) protein IE1-pp89 or M84 pr

151 The murine cytomegalovirus (MCMV) protein m4/gp34 is unique

152 In this study, we report that murine cytomegalovirus (MCMV) protein pM92 regulates vir

153 The murine cytomegalovirus (MCMV) proteins encoded by US22 g

154 pping mRNA region of M80.5 and protease, two murine cytomegalovirus (MCMV) proteins essential for vir

155 Murine cytomegalovirus (MCMV) rapidly induces activation

156 Compared to other organs, murine cytomegalovirus (MCMV) replication in the salivar

157 NK cell-mediated murine cytomegalovirus (MCMV) resistance (Cmv(r)) is und

158 fection of YAC transgenic NIH 3T3 lines with murine cytomegalovirus (MCMV) resulted in lower (more th

159 Using an established model of experimental murine cytomegalovirus (MCMV) retinitis in mice with ret

160 resistance or susceptibility to experimental murine cytomegalovirus (MCMV) retinitis in mice.

161 poptosis contribute to retinal damage during murine cytomegalovirus (MCMV) retinitis, and TNF-alpha i

162 apoptosis is involved in the pathogenesis of murine cytomegalovirus (MCMV) retinitis.

163 During primary infection, murine cytomegalovirus (MCMV) spreads systemically, resu

164 that IPC and dendritic cells (DC) recognize murine cytomegalovirus (MCMV) through TLR9.

165 a coli Tn3 was introduced into the genome of murine cytomegalovirus (MCMV) to generate a pool of vira

166 P-1 transgenic mice with a sublethal dose of murine cytomegalovirus (MCMV) to look for evidence of ac

167 ood-retina barrier (BRB) increases spread of murine cytomegalovirus (MCMV) to the eye after intraperi

168 Proteins associated with the murine cytomegalovirus (MCMV) viral particle were identi

169 Stable assembly of murine cytomegalovirus (MCMV) virions in differentiated

170 In this study, murine cytomegalovirus (MCMV) was used as a persistent i

171 odel to study the outcomes of acquisition of murine cytomegalovirus (MCMV) when neonates are breastfe

172 MV) with EC(50) of 6.8 and 7.5 microM and of murine cytomegalovirus (MCMV) with EC(50) of 11.3 microM

173 control replication of pathogens, including murine cytomegalovirus (MCMV), a double-stranded DNA bet

174 mber of the beta subfamily of herpesviruses, murine cytomegalovirus (MCMV), and now report that produ

175 entified three open reading frames (ORFs) in murine cytomegalovirus (MCMV), designated M82, M83, and

176 M33, encoded by murine cytomegalovirus (MCMV), is a member of the UL33 h

177 identified two open reading frames (ORFs) of murine cytomegalovirus (MCMV), M83 and M84, which are pu

178 cellular targets for infection by human and murine cytomegalovirus (MCMV), making it advantageous fo

179 o lymphocytic choriomeningitis virus (LCMV), murine cytomegalovirus (MCMV), or influenza A virus enha

180 In the case of murine cytomegalovirus (MCMV), the protein products of t

181 infected with human cytomegalovirus (HCMV), murine cytomegalovirus (MCMV), vaccinia (VV), and cowpox

182 Such is the case for murine cytomegalovirus (MCMV), where deletion of the M33

183 rget the mRNA encoding the protease (mPR) of murine cytomegalovirus (MCMV), which is essential for vi

184 hat this process is markedly enhanced by the murine cytomegalovirus (MCMV)-encoded CC chemokine, MCK2

185 Interrogation of murine cytomegalovirus (MCMV)-encoded cell-death suppres

186 ously expresses m157 (m157-Tg), which is the murine cytomegalovirus (MCMV)-encoded ligand for the Ly4

187 This murine cytomegalovirus (MCMV)-encoded protein, m12, rest

188 A murine cytomegalovirus (MCMV)-encoded protein, m157, has

189 as to determine whether adoptive transfer of murine cytomegalovirus (MCMV)-immune lymph node cells pr

190 on of these cytokines during adenovirus- and murine cytomegalovirus (MCMV)-induced hepatitis.

191 human fibroblasts as it has been shown to in murine cytomegalovirus (MCMV)-infected 4E-BP1(-/-) mouse

192 ymphocytic choriomeningitis virus (LCMV) and murine cytomegalovirus (MCMV).

193 urther analyzed after in vivo infection with murine cytomegalovirus (MCMV).

194 of the bacterium Listeria monocytogenes and murine cytomegalovirus (MCMV).

195 receptor Ly49H is required for resistance to murine cytomegalovirus (MCMV).

196 plasmid system to generate mutant strains of murine cytomegalovirus (MCMV).

197 ted mice and mice infected intranasally with murine cytomegalovirus (MCMV).

198 Intraglandular infection of mice with murine cytomegalovirus (MCMV; control: UV-inactivated MC

199 Both human cytomegaloviruses (HCMVs) and murine cytomegaloviruses (MCMVs) encode multiple genes t

200 igated the effect of systemic infection with murine cytomegalovirus on the distribution and dynamics

201 R3(WT) littermates with the beta-herpesvirus murine cytomegalovirus or the poxvirus vaccinia virus.

202 In murine cytomegalovirus, poorly conserved sequences dista

203 re we report the surprising finding that the murine cytomegalovirus protein M45, a component of viral

204 ovirus as the T-cell responses to irrelative murine cytomegalovirus remained unimpaired.

205 d accordingly, M33 is required for efficient murine cytomegalovirus replication in the mouse.

206 ritoneal inoculation of newborn animals with murine cytomegalovirus resulted in virus replication in

207 lar endothelial cells, laboratory strains of murine cytomegalovirus retain this ability.

208 Additionally, separation of the murine cytomegalovirus-specific T cells into CD8+ and CD

209 Experimental animals received murine cytomegalovirus-specific T cells or subsets of T

210 Adoptive transfer of murine cytomegalovirus-specific T cells, but not herpes

211 Murine cytomegalovirus strain v70 induces a rapid and se

212 R(-/-) mice exhibited increased clearance of murine cytomegalovirus that correlated with increased le

213 Murine cytomegalovirus triggers both apoptosis and necro

214 us which normally lacks invertible elements (murine cytomegalovirus), we created a genome composed of

215 , the genomes of the chimpanzee, rhesus, and murine cytomegaloviruses were searched for orthologues o

216 ed with either murine gammaherpesvirus 68 or murine cytomegalovirus, which are genetically highly sim

217 Cmv1, the gene that determines resistance to murine cytomegalovirus, which is encoded in the major NK

218 cess, we constructed a number of recombinant murine cytomegaloviruses with a second cleavage site ins