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1 to 8.9 +/- 0.9 (insulin), then 5.1 +/- 0.5 (muscimol)).
2 used by medial septum (MS) inactivation with muscimol.
3 less of whether its retrieval was blocked by muscimol.
4 imulated motor cortex using the GABA agonist muscimol.
5 lus (predator stress) altered sensitivity to muscimol.
6 icroinfusion of the GABA-A receptor agonist, muscimol.
10 nhibition of neurons in LPBN area (n=6) with muscimol (0.45 nmol per side) reduced dorsal PAG-evoked
11 1.7 g +/- 0.48) by simultaneous infusions of muscimol (0.6 mM/100 nl) into the IRt/PCRt (p < .01).
12 roinjections (100 nl) of the GABA(A) agonist muscimol (1 mm), induced the following: (1) a massive cu
13 cellular fluid, the GABA(A) receptor agonist muscimol (1 nmol/side), or the GABA(A) receptor antagoni
17 ent by D1 (SKF38393; 100ng/side) or GABA(A) (muscimol; 100ng/side) receptor agonists in ovariectomize
18 , ethanol (up to 50 mM) did not affect [(3)H]muscimol (15 nM) binding to the immunoprecipitated delta
20 Ethanol (1-50 mM) neither affected [(3)H]muscimol (3 nM) binding nor diazepam-insensitive [(3)H]R
22 te with free muscimol (100 microM-5 mM), PEG-muscimol (500 microM), or GABA (100 microM - 5 mM) subst
25 t 1, hamsters received DRN pretreatment with muscimol (87.6 pmol) or vehicle before DRN 8-OH-DPAT (6
26 ized rats before and after microinjection of muscimol (9 nl; 0.25 mM), a GABA-A receptor agonist, int
27 lonidine (an alpha-2 adrenergic agonist) and muscimol (a GABAa agonist) induce an inhibition of PS.
28 onjugate consisting of approximately 150-200 muscimols (a GABA receptor agonist) covalently joined to
32 thyl)-1-hydroxypyrazole (4-AHP) analogues of muscimol, a GABA(A) receptor agonist, has been synthesiz
37 esponses by microinjecting artificial CSF or muscimol, a neuronal inhibitor, into the DMH prior to in
41 naptic-type GABA(A) receptors, both THIP and muscimol additionally exhibited, to different degrees, s
42 nd behavioral studies have demonstrated that muscimol administered through the cranial meninges can p
44 vation of the primary motor cortex (M1) with muscimol affected anticipatory patterns in S1 and the th
50 lation the activity of three agonists, GABA, muscimol and 4,5,6,7-tetrahydoisoxazolo[5,4-c]pyridin-3(
51 dorsomedial striatum using the GABA agonists muscimol and baclofen decreased context-induced reinstat
53 ivation (achieved by presession injection of muscimol and baclofen) in a novel two-reward choice task
56 ction time (5CSRT) test, we showed that both muscimol and picrotoxin impaired attention (reduced accu
59 al circuits using the GABAA receptor agonist muscimol and validated the lesion placement using MRI.
61 class (e.g., pentobarbital, chloral hydrate, muscimol, and ethanol) produce analgesia and unconscious
63 bjects, quadrupedal rotations were evoked by muscimol application into SNpr sites that were distinct
66 as blocked by inactivation of the mPFCv with muscimol at the time of the initial experience with cont
67 mediate shock; and (2) BLA inactivation with muscimol attenuated the increase in Arc and c-fos mRNA i
68 of the medial prefrontal cortex by baclofen/muscimol (B/M) during testing attenuates renewal when te
76 ivated the vSub with GABA receptor agonists (muscimol+baclofen) before the context-induced relapse te
77 CeA or BLA by GABAA+GABAB receptor agonists (muscimol+baclofen, 0.03+0.3 nmol) on cue-induced methamp
79 Interestingly, in CBS-/+ mice treated with muscimol, BBB permeability was significantly decreased c
85 the effects of single DRN microinjections of muscimol, bicuculline (136 pmol), NMDA, MK-801 (10 pmol)
86 delta-subunit of GABA(A) receptors and [(3)H]muscimol binding to the immunoprecipitated delta-subunit
87 in the rat cerebellum as determined by [(3)H]muscimol binding to the immunoprecipitated receptor asse
89 application of the GABA(A) receptor agonist muscimol blocked spontaneous correlated increases in int
91 we microinfused the GABA-A receptor agonist muscimol (C4H6N2O2; 62.5, 125, 250 ng/side) or antagonis
93 the hypothesis that epidurally administered muscimol can prevent acetylcholine (Ach)-induced focal s
94 fusion of muscimol or fluorophore-conjugated muscimol caused a near complete shift in preference from
95 cells, GABA and the GABA(A) receptor agonist muscimol caused a rapid and transient increase in intrac
102 of cells in the PVT with the GABA(A) agonist muscimol could alter food intake in non-deprived rats.
104 FC neurons with the GABA agonists baclofen + muscimol decreased cue-induced heroin seeking on withdra
105 ebral infusion of the GABAA receptor agonist muscimol decreased the number of new HVC neurons by 56%.
107 pendent inactivation of either BM or BL with muscimol did not cause a reduction of conditioned freezi
108 ons of the gamma aminobutyric acid-A agonist muscimol did not impair acquisition of the odor discrimi
111 esponse to these two distinct stressors, rPH muscimol disrupted habituation to each stressor modality
112 icate that auditory thalamic inactivation by muscimol disrupts acute HPA axis response specifically t
115 e CE of rabbits (Oryctolagus cuniculus) with muscimol during NMR conditioning and/or during US testin
117 evented the effect, suggesting that GABA and muscimol elicit a conformational change that reduces acc
120 rized during the preictal phase, whereas the muscimol-evoked GABA(A) reversal potential remained unch
121 ound that 3alpha,5alpha-THP-, SKF38393-, and muscimol-facilitated lordosis was attenuated by infusion
123 pports the rationale of using transmeningeal muscimol for the treatment of intractable focal neocorti
125 biccuculine (GABA-A receptor antagonist) or muscimol (GABA-A receptor agonist) were injected prior t
126 of D-AP5 (glutamate receptor antagonist) and muscimol (GABAA receptor agonist) in the SubC virtually
128 VN, newborn cells did not survive in the UVN-muscimol group whereas the number of GABAergic pre-exist
132 Pu with GABA receptor agonists (baclofen and muscimol) immediately prior to reinstatement testing.
135 These data indicate that transmeningeal muscimol in a submillimolar concentration range can prev
137 s and increased the affinity for the agonist muscimol in human alpha1beta2/3gamma2L GABA(A) receptors
140 PL-IL or OFC infusion with the GABA agonist muscimol in the context of 2 flexible responding tasks:
144 epresentations in a novel environment during muscimol inactivation of the medial septal area, a manip
147 formal algorithmic behavioral analysis with muscimol inactivation, we provide causal evidence direct
148 ma-aminobutyric acid type A (GABA-A) agonist muscimol increased GSWD occurrence up to 37-fold, wherea
151 nt alpha-Ctx, however, could be displaced by muscimol indicating that most of the alpha-Ctx-binding s
152 altering the binding of the GABA agonist [3H]muscimol, indicating that this residue plays a key role
156 to restore MAP (n = 5), suggesting that the muscimol-induced reduction of cardiac rhythmic sSNA in D
158 r impaired performance, and both saline- and muscimol-infused rats appeared to use immediate task con
161 strategy switches but not reversals, whereas muscimol infusion into OFC impaired retention of reversa
165 rm retention of the trace eyeblink CR, using muscimol infusion to reversibly inactivate the IP nucleu
167 Inactivating the interpositus nucleus with muscimol infusions abolished these conditioned responses
169 ar surgery and training except they received muscimol infusions immediately before devaluation testin
173 ns were necessary for duration judgments, as muscimol infusions produced a specific impairment in ani
174 with striatal gamma activity, and intra-BLA muscimol infusions selectively reduced striatal gamma po
175 ted through amygdala temporary deactivation (muscimol infusions), which rescued the depressive-like b
176 th in vivo electrophysiology, we showed that muscimol inhibited prefrontal firing, whereas picrotoxin
181 itory thalamus was inactivated reversibly by muscimol injections during repeated loud noise exposures
183 eted subjects avidly consumed this solution, muscimol injections had no effect either on the volume c
186 approach involving inactivation of the BG by muscimol injections into the caudate nucleus of monkeys
188 esent experiment investigated the effects of muscimol injections into the rat dorsal anterior cingula
189 ques to characterize the effects of intra-MR muscimol injections on the consumption of either a 0.05
190 gestive behavior, we examined the effects of muscimol injections on the intake of a 3% NaCl solution
194 ibition of the contralateral intact RTN with muscimol instantly eliminated phrenic nerve discharge (P
195 by infusions of the GABA(A) receptor agonist muscimol into area 13 blocked the devaluation effect: th
196 As expected, injection of Kyn into RVLM or muscimol into commNTS virtually blocked the effect of ca
201 of microinjection of the neuronal inhibitor muscimol into the DMH on increases in HR, MAP and T(co)
205 To test this, we infused the GABAA agonist muscimol into the IC and the mu-opioid receptor antagoni
207 n that microinjections of the GABA-A agonist muscimol into the median raphe nucleus (MR) result in la
208 rebrospinal fluid control, microinjection of muscimol into the MnPN resulted in significantly higher
209 the gamma-aminobutyric acidA (GABAA) agonist muscimol into the nucleus accumbens shell (AcbSh) induce
210 lso observed food intake after injections of muscimol into the overlying ventricle or laterally adjac
213 0 into the accumbens and the GABA(A) agonist muscimol into ventral pallidum (i.e., "disconnection" me
214 mM solutions of a GABA(A) receptor agonist, muscimol, into the MnPN on Fos expression (Fos-IR) in th
216 l-PEG-qdots, and the removal of GABA or free muscimol led to a recovery of muscimol-PEG-qdot binding.
217 0 to 198 +/- 24 (insulin), then 133 +/- 23 (muscimol) LSNA gain in % control mmHg-1: from 3.9 +/- 0.
220 ability-driven feeding was carried out after muscimol-mediated inactivation of two frontal regions in
223 he current studies, we used intrahippocampal muscimol microinfusions to transiently inactivate the ma
225 ition of LSr neurons with local baclofen and muscimol microinjection (0.3/0.03 nmol) blocks expressio
229 ze, we demonstrated in rats that a bilateral muscimol (MSCI) inactivation (0.70 vs 0.26 and 0 nmol) o
232 hicle control), the GABA(A) receptor agonist muscimol, muscimol with the GABA(A) receptor antagonist
233 d qdots and PEG-qdots that lacked conjugated muscimol neither exhibited significant binding activity
236 Experiment 3 examined whether the effects of muscimol on aggression were dependent on prior social de
237 o a different class, mimicked the effects of muscimol on sIPSCs: it increased them at low (<or= 0.5 m
238 ural parameters suggested that the effect of muscimol on sucrose intake was not mediated by alteratio
239 h infusion of the GABA agonists baclofen and muscimol, on place acquisition and reversal learning.
242 thermore, CeA inactivation induced by either muscimol or CRF ASO administration immediately before re
243 or thalamic nuclei (ATN) by microinfusion of muscimol or fluorophore-conjugated muscimol caused a nea
244 etinal activity by intraocular injections of muscimol or gabazine during this period did not alter th
245 exogenously applied GABA(A) receptor agonist muscimol or glycine, either of which under control condi
246 ects of injecting the GABAA receptor agonist muscimol or the GABAA receptor antagonist bicuculline in
247 cular infusions of saline, GABA(A)R agonist (muscimol) or antagonist (gabazine), cell proliferation a
248 nd IL-31Tg mice with combinations of GABA-A (muscimol) or GABA-B (baclofen) receptor agonists 15 to 2
249 diazoxide plus the GABA(A) receptor agonist muscimol, or 5) glybenclamide plus the GABA(A) receptor
251 Unilateral microinjections of lidocaine, muscimol, or glutamate antagonists into the pTRG inhibit
252 stimuli were neutral, infusion of the GABAA, muscimol, or the NMDA receptor (NMDAR) antagonist ifenpr
253 the application of the high-affinity agonist muscimol partially rescued rapid desensitization compare
255 units) and investigated the binding of this muscimol-PEG-qdot conjugate to homomeric rho1 GABAC rece
258 eliminated the fluorescence halo produced by muscimol-PEG-qdots, and the removal of GABA or free musc
261 information transfer via Te2 inhibition with muscimol prevents any retrieval-evoked neuronal activity
262 inobutyric acid A (GABA(A)) receptor agonist muscimol, prior to a hypoglycemic clamp or under baselin
264 combined subthreshold doses of baclofen and muscimol produced a significant synergistic antipruritic
265 rates were significantly suppressed, whereas muscimol raised glucose infusion rates significantly com
268 activation of the CeA with the GABAA agonist muscimol reduced DAMGO (D-Ala2-NMe-Phe4-Glyol5-enkephali
273 ma-aminobutyric acid receptor type A agonist muscimol resulted in an impairment only when BLA was ina
274 and baseline food intake, whereas intra-BLA muscimol selectively blocked only DAMGO-induced food int
275 th bilateral injections of the GABAA agonist muscimol, selectively blocked the expression of SFiA whi
276 g with the obtained SAR indicate that 2a and muscimol share a common binding mode, which deviates fro
277 icantly affect orexin A-induced feeding, but muscimol significantly and dose dependently inhibited or
281 he resting condition, a dose of baclofen and muscimol that blocked a behaviorally induced increase in
283 SC of four macaques with the GABA(A) agonist muscimol to determine whether this treatment would preve
284 initial training, rats received infusions of muscimol to inactivate the pDMS immediately before sessi
285 f avoidance training, rats were infused with muscimol to pharmacologically inactivate the prelimbic c
286 macaques by intracerebral microinjection of muscimol (to inactivate) or bicuculline (to activate) to
290 ther saline or 0.005-, 0.05-, 0.5- or 5.0-mM muscimol was delivered through the cup, followed by a 20
293 tified, exposure of 1900 or fewer neurons to muscimol was sufficient to sustain whole-body general an
296 hypothesis, GABA receptor agonists (baclofen/muscimol) were microinjected into the anterior cingulate
297 hypothalamic injections of small volumes of muscimol, which disrupts normal synaptic functions, befo
298 tal cortex with the GABA(A) receptor agonist muscimol, which eliminates the protective effects of con
299 muL mixture of [(3)H] muscimol and unlabeled muscimol with a final concentration of 1.0mM was deliver
300 rol), the GABA(A) receptor agonist muscimol, muscimol with the GABA(A) receptor antagonist bicucullin
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