ライフサイエンスコーパス: muscularis

1 ation compared with the naive LPS-stimulated muscularis.

2 erminal centers, but prominent in the tunica muscularis.

3 hagocytes was observed within the intestinal muscularis.

4 morphology and ultrastructure of the tunica muscularis.

5 ould still be observed within the intestinal muscularis.

6 stry localized iNOS in phagocytes within the muscularis.

7 t iNOS messenger RNA induction in mucosa and muscularis.

8 BMP4 in the gizzard caused a thinning of the muscularis.

9 itial cells of Cajal (ICC) within the tunica muscularis.

10 al redistribution of flow between mucosa and muscularis.

11 hase) within the reperfused intestinal graft muscularis.

12 ution in ICC we mapped throughout the tunica muscularis.

13 ript for GPBAR1 were detected in gallbladder muscularis.

14 r mRNA induction within the small intestinal muscularis.

15 nic LPS and microspheres into the intestinal muscularis.

16 decrease in neutrophil infiltration into the muscularis after intestinal manipulation compared with w

17 massive extravasation of leukocytes into the muscularis after surgical manipulation of the small bowe

18 on of microsphere-laden monocytes within the muscularis, although a significant monocytic recruitment

19 eutrophils and monocytes into the intestinal muscularis and a functional suppression in jejunal circu

20 itment of monocytes and neutrophils into the muscularis and also averted jejunal circular muscle dysf

21 inflammatory response within the intestinal muscularis and causes intestinal muscle dysfunction.

22 Muscularis and mucosa extracts were isolated from the in

23 erferon-gamma mRNA was localized to both the muscularis and mucosa.

24 nsic sympathetic neurons innervating the gut muscularis and norepinephrine signaling to beta2 adrener

25 e-positive immune cells that infiltrated the muscularis and prevented the surgically induced reductio

26 d with respect to its transmural (mucosa vs. muscularis) and geographical (proximal jejunum, mid-smal

27 sed neutrophil infiltration into the jejunal muscularis; and (3) prevented SITx-induced suppression o

28 Resident macrophages within the tunica muscularis are known to play a crucial role in initiatin

29 ctivation of resident macrophages within the muscularis associated with dysmotility.

30 caused an increase in flow heterogeneity in muscularis at both high and low flow states, and in muco

31 ly upregulated in the hydrogen-treated graft muscularis but not mucosa before reperfusion.

32 r significantly less apoptosis in the tunica muscularis compared with tacrolimus monotherapy.

33 red from serum, peritoneal lavage fluid, and muscularis culture media.

34 Nitrite and NO production were measured in muscularis cultures.

35 rom all regions through the thickness of the muscularis demonstrated intrinsic pacemaker activity, an

36 oration in skeletal muscle of the dystrophia muscularis (dy/dy) mouse and its milder allelic variant,

37 The H2O2 increased in the muscularis externa 1-7 days after inflammation was induc

38 al manipulation leads to inflammation of the muscularis externa and disrupts motility.

39 rs of the myenteric and submucosal plexuses, muscularis externa and lamina propria of the gastrointes

40 sion; expression of NGF increased in colonic muscularis externa and mucosa/submucosa.

41 Normal human muscularis externa contained numerous macrophages that e

42 We localized PAR-2 to the muscularis externa of the rat colon by immunofluorescenc

43 The muscularis externa recovered and developed tolerance to

44 h but not Gli1 at E10.5; the 2 layers of the muscularis externa respond differently to Hedgehog signa

45 Histochemistry of the graft's muscularis externa showed a significant thickening due t

46 gainst esophageal circumference enlargement, muscularis externa thickening, and collagen deposition.

47 duction of POI activated the inflammasome in muscularis externa tissues of C57BL6 mice, and IL-1alpha

48 mechanisms to a subsequent insult within the muscularis externa.

49 ttributed to their release from the inflamed muscularis externa.

50 inflammatory response within the intestinal muscularis externa.

51 macrophages is distributed in the intestinal muscularis externa.

52 ned to enteric neurons and fibers within the muscularis externa.

53 e, nerve growth factor in the gastric fundus muscularis externae, brain-derived neurotrophic factor i

54 eta, TNF-alpha, iNOS, and COX-2 mRNAs within muscularis extracts after incision.

55 Antioxidant capacity and muscularis heme oxygenase-1 upregulation are possible pr

56 ry and electron microscopy of the intestinal muscularis identified the phagocytes as extravasating ED

57 nd beta2-adrenergic receptors in the oviduct muscularis implies that a basal endocannabinoid tone in

58 inflammatory responses within the intestinal muscularis in mouse and rat models of POI.

59 se in MMP-9 expression within the intestinal muscularis; increases in MMP-9 messenger RNA were induci

60 On postsurgical days 1 and 7, muscularis infiltrates were characterized immunohistoche

61 Muscularis infiltration of neutrophils and monocytes wer

62 ignificantly alleviated the small intestinal muscularis inflammation and prevented intestinal muscle

63 Surgically induced intestinal muscularis inflammation has been hypothesized as a mecha

64 gically altered colon or by small intestinal muscularis inflammation itself.

65 handling initiates a molecular and cellular muscularis inflammation that has been associated with iN

66 s and monocytes were counted, and intestinal muscularis inflammatory mediators were quantified by qua

67 mopoietic cells contribute to TLR4-sensitive muscularis inflammatory signaling, but nonhemopoietic TL

68 The serosal/muscularis layer remained relatively unaffected.

69 iNOS mRNA was detected in the mucosal and muscularis layers after the initiation of colitis.

70 tramural distribution to mucosal and serosal/muscularis layers were determined using the radioactive

71 response within the postsurgical intestinal muscularis, leading to an exacerbation of postoperative

72 Muscularis leukocytic infiltrates were characterized.

73 that surgical trauma is followed by resident muscularis macrophage activation and the upregulation, r

74 pro-inflammatory phenotype when compared to muscularis macrophages (MMs), which displayed a tissue-p

75 plastic, microbiota-driven crosstalk between muscularis macrophages and enteric neurons that controls

76 We demonstrate that, in the steady state, muscularis macrophages regulate peristaltic activity of

77 -2 messenger RNA and protein within resident muscularis macrophages, a discrete subpopulation of myen

78 The decrease in blood flow to the muscularis may contribute to loss of intestinal wall per

79 protein expression was increased within the muscularis microvasculature, and ICAM-1 and LFA-1 were e

80 the 'neuro-effector' junction in the tunica muscularis might consist of synaptic-like connectivity w

81 villous width, villous perimeter per 100 mum muscularis mucosa (a measure of epithelial surface area)

82 and villous cross sectional area per 100 mum muscularis mucosa (a measure of villous compartment volu

83 thelial basement membrane and the underlying muscularis mucosa (lamina propria lymphocytes), or in or

84 blood vessels, which are located between the muscularis mucosa and circular muscular layer of the hum

85 h and intestine at E16; and after birth, the muscularis mucosa and villus smooth muscle consist prima

86 s, loss of smooth muscle in villus cores and muscularis mucosa as well as crypt hyperplasia.

87 d be due to altered properties of ICs or the muscularis mucosa in the bladders of these animals.

88 Adenocarcinoma invasive deeper than the muscularis mucosa is associated with a significant incre

89 contains cell-populated mucosa and an intact muscularis mucosa layer.

90 d preservation of the muscularis propria and muscularis mucosa was determined histologically.

91 ercent of the Delay group had atrophy of the muscularis mucosa, whereas 19% of Immediate animals had

92 to the loss of visceral SMCs disrupting the muscularis mucosa.

93 urothelium and bladder detrusor, termed the muscularis mucosa.

94 erosa (median, 245 vs 64 mum; P = .019), and muscularis mucosae (median, 451 vs 80 mum; P = .031) wer

95 , 5-HT(4) receptor agonism in the rat tunica muscularis mucosae (TMM) assay, and for 5-HT(3) receptor

96 6 weeks, alpha 8 expression localized to the muscularis mucosae and villus core.

97 In rabbit colonic muscularis mucosae cells, tyrosine-phosphorylated protei

98 vide a basis for analyses of the role of the muscularis mucosae in ISC regulation.

99 stologic grade, lymphocytic infiltration, or muscularis mucosae invasion, was associated with cancer

100 ononuclear leukocytes and hyperplasia of the muscularis mucosae smooth muscle cells (M-SMCs).

101 ved stromal stem cells, smooth muscle of the muscularis mucosae, and smooth muscle surrounding the ly

102 ts heavily to the circular muscle layer, the muscularis mucosae, and to other myenteric neurons.

103 does not preclude cancer invasion beyond the muscularis mucosae, cautioning against the use of mucosa

104 al architecture, demonstrated by loss of the muscularis mucosae, deterioration of the extracellular m

105 smooth muscle layer of the colon, the tunica muscularis mucosae, were examined using the patch clamp

106 cle layer and, later, to the villus core and muscularis mucosae.

107 id lymphocytic infiltrate extending into the muscularis mucosae.

108 significant leukocyte extravasation into the muscularis of all groups.

109 ls of the islet and a subset of cells in the muscularis of arteries in a distribution identical to en

110 intestinal segments and within the isolated muscularis of chronically rejecting intestinal allograft

111 aused a significant up-regulation within the muscularis of ICAM-1 and P-selectin messenger RNA.

112 athways exist within the thick-walled tunica muscularis of large mammals.

113 cells of Cajal (ICC) exist within the tunica muscularis of the gastric antrum, and these cells serve

114 uted in specific locations within the tunica muscularis of the gastrointestinal (GI) tract.

115 We isolated ENS progenitors from tunica muscularis of the small intestine of newborn (postnatal

116 ocalized by immunofluorescence in the tunica muscularis of the vas deferens.

117 ed four populations of ICC within the antral muscularis on the basis of anatomical location.

118 um of the heart, skeletal muscle, intestinal muscularis, or brain capillaries or the nondiaphragmed f

119 ee of trauma, the activation of resident gut muscularis phagocytes, and the extent of cellular infilt

120 xpressed in leukocytes within the intestinal muscularis plays a major role in mediating smooth muscle

121 ochondrial function affects the IJP, colonic muscularis preparations were treated with the mitochondr

122 ecruitment of immune cells to the intestinal muscularis, preventing loss of smooth muscle contractili

123 n of Ba2+ (1-100 microM) to strips of tunica muscularis produced depolarization of cells along the su

124 11) had a smaller area of tissue outside the muscularis propria (P = 0.04) compared with the CRM-nega

125 the submucosa low signal intensity, and the muscularis propria an intermediate signal intensity.

126 -beta 1 was localized in muscle cells of the muscularis propria and in culture.

127 cm in diameter with infiltration through the muscularis propria and into the subserosal fat.

128 Width differences of internal muscularis propria and mucularis mucosae were associated

129 osis was quantified, and preservation of the muscularis propria and muscularis mucosa was determined

130 Chronic rejection caused thickening of muscularis propria by both hyperplasia (175.5%) and hype

131 arly in the definition of penetration of the muscularis propria by rectal cancer (74% vs 58%).

132 2 days old Wistar rats, or sections from the muscularis propria containing the myenteric plexus from

133 In the esophagus and rectum, the muscularis propria could be visualized as separate circu

134 and intramesorectal groups compared with the muscularis propria group were 0.32 (0.16-0.64) and 0.48

135 1%) for intramesorectal, and 13% (8-21%) for muscularis propria groups.

136 ble lesions that appear to be limited to the muscularis propria have a high chance of cure with sphin

137 ificant decrease in goblet cell hyperplasia, muscularis propria hypertrophy, villus blunting, and exp

138 in the proportion of each plane of surgery: muscularis propria in 95 of 399 (24%) specimens, intrame

139 the marked inflammatory infiltrate into the muscularis propria indicates that the graft muscle is in

140 -distal rectum with minimal extension beyond muscularis propria into the mesorectal fat, but without

141 llary transitional cell carcinoma (TCC) with muscularis propria invasion (Fig 1).

142 ic subepithelial tumors originating from the muscularis propria layer and larger than 2 cm, complete

143 re smaller than 5 cm and originated from the muscularis propria layer of the stomach, as shown by end

144 ic subepithelial tumors originating from the muscularis propria layer, and to evaluate its efficacy a

145 ion, particularly those originating from the muscularis propria layer.

146 Smooth muscle cells were isolated from muscularis propria of stricturing CD or normal margins.

147 rcinoma or urothelial carcinoma invading the muscularis propria of the bladder.

148 sa and submucosa on the one hand, and of the muscularis propria of the bowel wall on the other, it mi

149 heteroechoic solid mass originating from the muscularis propria of the distal esophagus.

150 The muscularis propria of the esophagus is organized into ci

151 infection in the smooth muscle cells of the muscularis propria of the intestine.

152 dvanced (T3 with >/=5 mm invasion beyond the muscularis propria or T4) tumours from 35 UK centres wer

153 c plane surgery compared with surgery in the muscularis propria plane (HR 0.57 [0.38-0.85], p=0.006)

154 intramesocolic (mean 2109 [1273] mm(2)) and muscularis propria plane (mean 1447 [913] mm(2)) surgery

155 ed with intramesocolic (mean 30 [16] mm) and muscularis propria plane (mean 21 [12] mm) surgery, whic

156 te (intramesorectal) in 398 (34%), and poor (muscularis propria plane) in 154 (13%).

157 TEC architecture is identical to native with muscularis propria staining for actin, acetylcholinester

158 ignificant increase in the distance from the muscularis propria to the mesocolic resection margin wit

159 an distance of full-thickness atrophy of the muscularis propria was 0.10 mm (IQR 0-0.60 mm) in the De

160 monstrated, and in four (57%), breach of the muscularis propria was correctly predicted.

161 Mean cross-sectional tissue area outside the muscularis propria was significantly higher with mesocol

162 rea of surgically removed tissue outside the muscularis propria was smaller in APR specimens (n = 27)

163 Intestinal smooth muscle (muscularis propria) from individuals with FVM had reduce

164 icted T2/T3a/T3b (less than 5 mm spread from muscularis propria), regardless of MRI N stage.

165 e mucosa, 16 to the submucosa, and 13 to the muscularis propria, and 55 were transmural.

166 ma, histologically normal mucosa, submucosal muscularis propria, and histologically normal mucosa dis

167 Studies localized TGF-beta within the muscularis propria, identified the cellular source, meas

168 gastric wall infiltration (submucosa, n = 4; muscularis propria, n = 3; serosa, n = 1).

169 al subepithelial tumors originating from the muscularis propria, respectively.

170 external (median, 929 vs 632 mum; P = .013) muscularis propria, serosa (median, 245 vs 64 mum; P = .

171 influx of neutrophils into the submucosa and muscularis propria.

172 with both hyperplasia and hypertrophy of the muscularis propria.

173 gastrointestinal tumors originating from the muscularis propria.

174 gastrointestinal tumors originating from the muscularis propria.

175 ntermediate urothelial cells, as well as the muscularis propria.

176 teric neurons and smooth muscle cells in the muscularis propria.

177 The developing muscularis (propria and mucosae) showed accentuated alph

178 These data suggest that the tunica muscularis provides a suitable microenvironment for the

179 inflammatory response within the intestinal muscularis, resulting in paralytic ileus.

180 Preconditioning of the muscularis showed significant cross-tolerance to the fun

181 ngly, positively hybridized cells within the muscularis tended to preferentially localize to the myen

182 nflammatory response in the small intestinal muscularis that contributes to postoperative ileus.

183 n about the specific cells within the tunica muscularis that express PARs and the mechanisms leading

184 inflammatory response within the intestinal muscularis that is associated with a subsequent decrease

185 ocal inflammatory cascade within the colonic muscularis that mediates smooth muscle dysfunction, whic

186 termediate on T2-weighted images and that of muscularis was low.

187 ed in diameter and hypertrophy of the tunica muscularis was observed oral to the obstruction site.

188 lease and apoptosis of uterine epithelia and muscularis were hallmarks of the LPS model.

189 Zymography analysis, performed in muscularis whole mounts in situ, indicated that MMP-9 an

190 Leukocyte extravasation was investigated in muscularis whole mounts.

191 try for neutrophils was performed in jejunal muscularis whole mounts.

192 emical techniques were applied to intestinal muscularis whole-mounts.

193 d capillary transit times in both mucosa and muscularis, with relative dispersions (SD/Mean) ranging

194 balanced by a decrease in blood flow to the muscularis, with total mesenteric flow remaining unchang