ライフサイエンスコーパス: myectomy

1 ) after pacing (p = 0.02 for comparison with myectomy).

2 nts, all of whom had MV surgery (with septal myectomy).

3 cal results are comparable to that of septal myectomy.

4 e, in this area, ASA still seems inferior to myectomy.

5 at one year are similar to those of surgical myectomy.

6 s who are most likely to benefit from septal myectomy.

7 he 45 patients who underwent isolated septal myectomy.

8 predictive of clinical outcome after septal myectomy.

9 bstructive cardiomyopathy who undergo septal myectomy.

10 of patients with HCM who underwent surgical myectomy.

11 otion of the MV is relieved through adequate myectomy.

12 HOCM) undergoing extended transaortic septal myectomy.

13 and septal thickness that underwent isolated myectomy.

14 ected patients, and when needed, by surgical myectomy.

15 a Siemens 1.5 T scanner, followed by septal myectomy.

16 procedural complication rate exceeds that of myectomy.

17 s of age have better symptom resolution with myectomy.

18 ears, 17 women) subsequently needed surgical myectomy.

19 nspecting their heart samples extracted from myectomy.

20 dapt the repair, often employing an extended myectomy.

21 a clinical diagnosis of HCM underwent septal myectomy.

22 25 were treated by PTSMA and 26 patients via myectomy.

23 septal myocardial ablation (PTSMA) or septal myectomy.

24 illator placement, 5 valve surgery, 2 septal myectomy, 1 aortic arch replacement, 1 myocardial bridge

25 ession of HCM, with all 5 requiring surgical myectomy, 3 of the 5 having a family history of sudden c

26 e 117 patients who underwent surgical septal myectomy, 47 (40%) developed left bundle branch block.

27 , p = 0.0009), and more frequently underwent myectomy (60% vs. 38%, p = 0.002).

28 hed patients who underwent isolated surgical myectomy (8-year survival estimate, 79% versus 79%; P=0.

29 s judged unsuitable for conventional myotomy/myectomy, a novel surgical strategy was designed to remo

30 jacent right bundle tissue, whereas surgical myectomy affects the endocardial portion of the basal an

31 We sought to determine the outcome of myectomy after unsuccessful alcohol ablation.

32 non-pharmacologic intervention with surgical myectomy, alcohol ablation, or pacing; outflow gradient

33 Septal myectomy and alcohol septal ablation for severely sympto

34 Surgical septal myectomy and alcohol septal ablation relieve left ventri

35 phologic differences that result from septal myectomy and alcohol septal ablation using cardiac magne

36 rily centered on the choice between surgical myectomy and alcohol septal ablation.

37 Surgical myectomy and dual-chamber pacing improve subjective meas

38 vere obstructive symptoms requiring surgical myectomy and implantation of an implantable cardioverter

39 Both myectomy and PTSMA reduce LVOT obstruction and significa

40 This review discusses the indications for myectomy and surgical technique for treating benign esse

41 t and protein levels were analyzed in septal myectomy and transplant specimens from 46 genotyped HCM

42 ted more inferiorly in the basal septum than myectomy and usually extending into the right ventricula

43 ents had surgical relief of obstruction (91% myectomy) and 6 (2%) alcohol septal ablation.

44 Twenty patients underwent surgical myectomy, and 19 received dual-chamber pacemakers based

45 herapeutic hypothermia, advances in surgical myectomy, and alcohol ablation.

46 m 76+/-57 to 9+/-17 mm Hg (p = 0.0001) after myectomy, and from 77+/-61 to 55+/-39 mm Hg (p = 0.07) a

47 s, including septal alcohol ablation, septal myectomy, and implantable cardioverter defibrillators, a

48 ulation, and to patients undergoing surgical myectomy, as well, without an increased risk of sudden c

49 er-matched patients who had undergone septal myectomy at Mayo Clinic (P<0.0001).

50 utaneous alcohol septal ablation or surgical myectomy at Mayo Clinic between 1999 and 2003 were revie

51 PTSMA, 62 +/- 43 mm Hg vs. 7 +/- 7 mm Hg for myectomy, both p < 0.0001).

52 7 for PTSMA, 3.3 +/- 0.5 vs. 1.5 +/- 0.7 for myectomy, both p < 0.0001).

53 on and 2.4 +/- 0.6 cm vs. 1.7 +/- 0.2 cm for myectomy, both p < 0.001).

54 Myectomy can be successfully performed after failed alco

55 .6+/-2.8 to 8.7+/-3.0 min (p = 0.0003) after myectomy compared with a change from 6.4+/-2.1 to 7.0+/-

56 rdiomyocytes from 26 HCM patients undergoing myectomy compared with those from nonfailing nonhypertro

57 ents, additional procedures on MV and PM (+/-myectomy) could be considered.

58 Additional myectomy did not reduce the risk for reoperation (P=0.92

59 Myectomy does not show additional advantages, and becaus

60 There are four reasons to consider myectomy for patients with BEB.

61 nary ethanol with standard therapy (surgical myectomy) for the treatment of hypertrophic obstructive

62 cardiomyopathy who underwent isolated septal myectomy from 1986 to 1992 were analyzed.

63 athy referred for alcohol septal ablation or myectomy from 1998 to 2006, 138 patients (median age, 64

64 e resting PG remained lower in the PTSMA and myectomy groups (24 +/- 19 mm Hg and 11 +/- 6 mm Hg, res

65 operative mortality rate for isolated septal myectomy in most centers is <1%.

66 lly effective compared to internal sphincter myectomy in short-term follow-up.

67 o establish the risks and benefits of septal myectomy in the modern surgical era.

68 d with HCM and severe basal LVOTO undergoing myectomy in whom the diagnosis of AFC was suspected by t

69 ators working in high-volume centers, septal myectomy is highly effective with a >90% relief of obstr

70 the route of the septal perforators, whereas myectomy is not.

71 Long-term survival after myectomy is similar to that of the general population an

72 Procedural morbidity and mortality risk with myectomy is similar to, and in some institutions less th

73 Although surgical myectomy is the primary treatment for amelioration of ou

74 ft ventricular outflow obstruction, surgical myectomy may be indicated, with little current role for

75 Therefore, isolated myectomy may not relieve outflow obstruction and symptom

76 Both dual-chamber pacing and surgical myectomy may result in subjective symptom improvement.

77 y in 3; mitral valve repair in 2; and septal myectomy, mitral valve replacement, aortoplasty, subaort

78 After surgical myectomy, more patients were on medications (p < 0.05) a

79 Ventricular septal myotomy/myectomy (Morrow procedure) is the standard surgical opt

80 in end-stage failing heart, and 76 +/- 6% in myectomy muscle samples (donor versus myectomy p < 0.05)

81 ined in HCM patients before and after septal myectomy (n = 24) and alcohol septal ablation (n = 24).

82 nts evaluated from 1983 to 2001: 1) surgical myectomy (n = 289); 2) LV outflow obstruction without op

83 ion (n=49) or the Maze procedure at surgical myectomy (n=72).

84 In this nonrandomized study, myectomy offered greater reduction in left ventricular o

85 y sought to determine the impact of surgical myectomy on long-term survival in hypertrophic cardiomyo

86 apamil, disopyramide) and the septal myotomy-myectomy operation, which is the standard of care for se

87 A total of 2,107 septal myectomy operations performed in adults from January 199

88 cular obstruction, septal reduction therapy (myectomy or alcohol septal ablation) is recommended.

89 al reduction therapy, either surgical septal myectomy or alcohol septal ablation.

90 be considered before proceeding to surgical myectomy or alternate strategies.

91 -up of 327 days (90-743 days) after surgical myectomy (or alcohol septal ablation), 92% and 95% of pa

92 abolition of subaortic gradients by surgical myectomy (or percutaneous alcohol septal ablation) resul

93 nsplantation for end-stage failure, surgical myectomy (or selectively, alcohol septal ablation) to al

94 to prevent sudden death, drugs and surgical myectomy (or, alternatively, alcohol septal ablation) fo

95 agnosis, degree of hypertrophy, incidence of myectomy, or family history of HCM or sudden death.

96 6% in myectomy muscle samples (donor versus myectomy p < 0.05).

97 rom 19.4+/-6.4 to 22.2+/-6.5 ml/kg/min after myectomy (p = 0.004), whereas the pacing group did not e

98 nd gender-matched patients who had undergone myectomy (P=0.18).

99 frequency in patients with or without prior myectomy (P=0.84).

100 Myectomy patients <or=65 years of age had significantly

101 mpared with age- and gradient-matched septal myectomy patients at the Mayo Clinic.

102 red to nonoperated obstructive HCM patients, myectomy patients experienced superior survival free fro

103 Ninety percent of myectomy patients experienced symptomatic improvement as

104 ndle branch block developed in 46% of septal myectomy patients, and right bundle branch block was evi

105 Surgical myectomy performed to relieve outflow obstruction and se

106 Surgical septal myectomy permanently abolishes systolic anterior motion

107 Septal myectomy provides consistent resection of the obstructin

108 Surgical myectomy provides excellent relief of symptoms in most p

109 fit and restoration of quality of life, with myectomy providing a long-term survival similar to that

110 Septal myectomy reduces or eliminates left ventricular outflow

111 Myectomy remains essential for treating blepharospasm pa

112 Surgical myectomy resulted in a significantly higher incidence of

113 donor hearts, explanted failing hearts, and myectomy samples from patients with HCM.

114 In this retrospective study, septal myectomy seems to reduce mortality risk in severely symp

115 tive surgical strategies to standard myotomy/myectomy, similar to those described here.

116 Previous data on septal myectomy (SM) and alcohol septal ablation (ASA) in obstr

117 outcomes of septal ablation (SA) with septal myectomy (SM) for treatment of hypertrophic obstructive

118 nges in myocardial efficiency and effects of myectomy surgery.

119 -II protein levels were higher in HCM septal myectomies than in nonfailing control hearts and in 60-w

120 After isolated septal myectomy, the percentage of patients with MR grade >/=3

121 With septal myectomy, there was a discrete area of resected tissue c

122 alleles of FHOD3-V1151I were detected in HCM myectomy tissue.

123 Multivariate analysis showed myectomy to have a strong, independent association with

124 e the outflow gradient in which an extensive myectomy trough (wider at its apical than basal extent)

125 , 1-, 5-, and 10-year overall survival after myectomy was 98%, 96%, and 83%, respectively, and did no

126 Myectomy was performed at 19 +/- 15 months after ablatio

127 ed pre-operatively; in 1,830 (96.1%), septal myectomy was performed without a direct MV procedure.

128 omyopathy (HCM) patients undergoing surgical myectomy, we sought to determine the association between

129 judged as not optimal candidates for septal myectomy, were referred for management of severe, drug-r

130 s to compare the treatment effects of septal myectomy with dual-chamber pacing in patients with hyper

131 lly reviewing all studies comparing ASA with myectomy with long-term follow-up, (aborted) sudden card