ライフサイエンスコーパス: myelin basic protein

1 fic enolase), astrocytes (S100b), and axons (myelin basic protein).

2 osphorylation in a robust in vitro substrate myelin basic protein.

3 habeta TcR, which recognizes the autoantigen myelin basic protein.

4 cted, and Western blotting indicated reduced myelin basic protein.

5 patients' sera contained an IgG specific to myelin basic protein.

6 A vaccine for MS, encoding full-length human myelin basic protein.

7 cephalitogenic determinant of the guinea pig myelin basic protein.

8 and phosphorylated the artificial substrate, myelin basic protein.

9 ith the immunodominant N-terminal epitope of myelin basic protein.

10 milar increase in its kinase activity toward myelin basic protein.

11 mined by localization of sodium channels and myelin basic protein.

12 immunized with encephalitogenic peptides of myelin basic protein.

13 using in situ hybridization and detection of myelin basic protein.

14 odies in astrocytes label with antibodies to myelin basic protein.

15 rmin (Ermn), and by immunohistochemistry for myelin basic protein.

16 so determined the location of methylation on myelin basic protein.

17 t are both immunodeficient and deficient for myelin basic protein.

18 lowed by neuron-specific enolase and finally myelin basic protein.

19 transcription factor Oct-6 and expression of myelin basic protein.

20 le sclerosis and recognizes the self-antigen myelin basic protein.

21 does not occur due to a genetic deletion of myelin basic protein.

22 an autoreactive, EAE T cell clone 172.10 and myelin basic protein (1-11) presented by class II MHC I-

23 Finally, treatment of myelin basic protein(1-11) T cell receptor transgenic mi

24 nance imaging and sections immunostained for myelin basic protein, 15/28 being mixed white and grey m

25 itogenic rat T cell clone C14 recognizes the myelin basic protein 69-89 peptide in the context of the

26 mice expressing TL3A6, an MS patient-derived myelin basic protein 83-99-specific TCR.

27 compositions (based on the binding motif of myelin basic protein 85-99 to HLA-DR2) have been develop

28 or (TCR) that also recognizes a peptide from myelin basic protein, a candidate MS autoantigen.

29 purified PRMT7 actively methylated histones, myelin basic protein, a fragment of human fibrillarin (G

30 We show that myelin basic protein, a protein essential for CNS myelin

31 e show that GPR17 activation also diminishes myelin basic protein abundance by lessening stimulation

32 n by TCR transgenic T cells specific for the myelin basic protein Ac1-11, as well as reduce NO produc

33 SCI and EAE were compared in two types of myelin basic protein Ac1-11-specific T-cell receptor tra

34 ith the immunodominant N-terminal epitope of myelin basic protein, Ac1-9.

35 not the apparent Km values of PKC betaII for myelin basic protein; activation was independent of phos

36 We find that myelin basic protein acts as a lipid coupler between two

37 Myelin basic protein and 2', 3'-cyclic nucleotide 3'-pho

38 rgo autophosphorylation and to phosphorylate myelin basic protein and histone H3 on serine and threon

39 ptor subunit NR-2A), and myelin-derived Ags (myelin basic protein and myelin oligodendrocyte glycopro

40 Myelin basic protein and neurofilament immunolabelling d

41 Akt-DD mice exhibited enhanced expression of myelin basic protein and promoter of proteolipid protein

42 mmune response, and a small response against myelin basic protein and proteolipid protein epitopes.

43 d myelin basic protein (r = 0.58, P < 0.01), myelin basic protein and T(2) (r = -0.59, P < 0.01), and

44 postmortem sections show concurrent loss of myelin basic protein and TAL from sites of demyelination

45 on tag (Myc-His) and their ability to cleave myelin basic protein and the insulin B chain.

46 that Ang II stimulates IKK to phosphorylate myelin basic protein and the p65 subunit of NF-kappaB.

47 face marker O1 and the mature OL marker MBP (myelin basic protein), and also prevents the long-term r

48 ogenous proteins in vitro, including casein, myelin basic protein, and bovine serum albumin.

49 duced levels of myelin regulatory factor and myelin basic protein, and decreased numbers of myelinate

50 proteins including ubiquitin, beta-thymosin, myelin basic protein, and hemoglobin were spatially mapp

51 tructural myelin proteins, such as periaxin, myelin basic protein, and myelin protein zero, was decre

52 N-terminal domain of fibrillarin (GST-GAR), myelin basic protein, and recombinant human histones H2A

53 onding to sequences contained in histone H4, myelin basic protein, and SmD3 were methylated.

54 with or without vitamin D(3), immunized with myelin basic protein, and studied for signs of EAE and f

55 midinase-like protein-2 (CRMP2/DRP2/DPYSL2), myelin basic protein, and syntaxin-binding protein-1 (ST

56 er), the number of axons, immunostaining for myelin basic protein, and TUNEL assays were performed.

57 orming growth factor (TGF)-beta secretion by myelin basic protein- and MOG-peptide-specific T cells,

58 a Multiple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobil

59 ation treatment biased the class of elicited myelin basic protein antibodies from IgG2a to IgG1 and I

60 e opposite charges on the lipid bilayers and myelin basic protein, as well as on the repulsive forces

61 Serum myelin basic protein at 24 and 72 hours correctly classi

62 In solution and in the lipid-free state, myelin basic protein belongs to that class of proteins.

63 ods successfully detected phosphorylation of myelin basic protein by PKC-alpha kinase.

64 tively induced in Lewis rats by injection of myelin basic protein emulsified in complete Freund's adj

65 ferent affinities for the H-2K(k)-restricted myelin basic protein epitope consisting of amino acids 7

66 owever, recent clinical trials with APL of a myelin basic protein epitope revealed limitations of thi

67 for AEP in processing of the immunodominant myelin basic protein epitope.

68 issue, Aggarwal et al. present evidence that myelin basic protein, essential for myelination by oligo

69 he apoptotic pathway specifically in mature, myelin basic protein expressing oligodendrocytes (MBP-iC

70 Myelin basic protein expression and CC1(+) oligodendrogl

71 In addition, nsf mutants exhibit defects in Myelin basic protein expression and in localization of s

72 chloro-1H-indole-3-propionic acid) decreases myelin basic protein expression levels mainly by trigger

73 The onset of myelination, as seen by myelin basic protein expression, was approximately 54 we

74 cked activation of Rac1 and cdc42 as well as myelin basic protein expression.

75 P10 pups, showed bilateral reduction in MBP (myelin basic protein) expression with 24 h exposure to 8

76 ed cisplatin-induced changes in coherency of myelin basic protein fibers in the cingular cortex and l

77 to 15.4 +/- 2.1 mm(3) and augmented loss of myelin basic protein from 13.4 +/- 6.0 to 70.6 +/- 5.3%.

78 study and our previous reports, a model for myelin basic protein gene control is proposed.

79 To better understand the regulation of myelin basic protein gene expression in mammalian cells,

80 In the present study, we found that the myelin basic protein gene is one of the genes that is re

81 s have been identified in both mouse and rat myelin basic protein gene promoters using RNA ligase-med

82 s-elements that are important for regulating myelin basic protein gene transcription.

83 marrow cells express products of the neural myelin basic protein gene, and we demonstrate here that

84 Golli proteins, products of the myelin basic protein gene, can modulate voltage-gated Ca

85 Golli proteins, products of the myelin basic protein gene, function as a new type of mod

86 ein, an alternatively spliced product of the myelin basic protein gene, plays a critical role in regu

87 y coupled to the encephalitogenic guinea pig myelin basic protein (Gp-MBP(72-89)) peptide, could prev

88 evant multimeric peptides such as guinea pig myelin basic protein GPBP(72-84) MAP (a dendrimeric octa

89 major encephalitogenic peptide of guinea pig myelin basic protein (GPMBP; i.e., neuroantigen or NAg).

90 racellular myelin compaction and the role of myelin basic protein has been investigated, the forces t

91 nd the encephalitogenic 73-87 determinant of myelin basic protein (i.e., the neuroantigen, or NAg) co

92 Expression of myelin basic protein in differentiating oligodendrocytes

93 ed myelination, and histological analysis of myelin basic protein in human postmortem specimens confi

94 2 in preventing the precocious expression of myelin basic protein in immature oligodendrocytes.

95 ession of Nkx2.2 represses the expression of myelin basic protein in oligodendrocyte progenitors.

96 ssessed with immunocytochemical staining for myelin basic protein in single-labelled neurons.

97 Degraded myelin basic protein in the gray matter medial to the CC

98 auto-phosphorylation and phosphorylation of myelin basic protein in vitro.

99 These results were corroborated by myelin basic protein intensity and staining pattern in t

100 esence of proteolytic autoantibodies against myelin basic protein is now considered as a characterist

101 luding Pou3f1, Egr2, myelin protein zero and myelin basic protein, is reduced.

102 In this paper, we show that TAL, but not myelin basic protein, is specifically cleaved by human G

103 this study, we show that Mst1 is a prominent myelin basic protein kinase activated by proapoptotic st

104 comprised of myelinated fibers, with reduced myelin basic protein levels (MBP) compared to levels in

105 munofluorescence for 4-hydroxy-2-nonenal and myelin basic protein localized free-radical-induced oxid

106 sidues from the acetylated N-terminal end of myelin basic protein: mass-to-charge (m/z) 795.81 (+2) m

107 at serum S100b, neuron-specific enolase, and myelin basic protein may aid in outcome classification o

108 ociated with multiple sclerosis (MS) and the myelin basic protein (MBP) 85-99-specific HLA-DR2-restri

109 RMTC expressing a myelin basic protein (MBP) 89-101-IAs-zeta receptor can

110 CD4+CD25+ RMTCs expressing a myelin basic protein (MBP) 89-101-IAs-zeta receptor, unl

111 ly, we reported a strong interaction between myelin basic protein (MBP) and Abeta peptides that resul

112 into mature oligodendrocytes expressing both myelin basic protein (MBP) and adenomatus polyposis coli

113 y a significant role in the fragmentation of myelin basic protein (MBP) and demyelination.

114 Mice that have been immunized with myelin basic protein (MBP) and infected exhibit the feat

115 cterization of a label-less immunosensor for myelin basic protein (MBP) and its interrogation using a

116 isoning also causes adduct formation between myelin basic protein (MBP) and malonylaldehyde, a reacti

117 stages demonstrated widespread reduction of myelin basic protein (MBP) and myelin in the sensorimoto

118 tially associates with the mRNA encoding the myelin basic protein (MBP) and rescues MBP expression fr

119 ensor for the simultaneous quantification of Myelin Basic Protein (MBP) and Tau proteins in cerebrosp

120 igned and optimized based on the autoantigen myelin basic protein (MBP) and the MBP-derived peptide M

121 e TCR (MS2-3C8) bound to a self-peptide from myelin basic protein (MBP) and the multiple sclerosis-as

122 lesions were found to contain citrullinated myelin basic protein (MBP) and were surrounded by astroc

123 Transcripts of myelin basic protein (mbp) are expressed in normal and r

124 ography and mass spectrometry, we identified myelin basic protein (MBP) as a prominent brain parenchy

125 A real-time fluorogenic kinase assay using myelin basic protein (MBP) as a substrate is reported.

126 acks an actin-based cytocortex, and requires myelin basic protein (MBP) as its major structural compo

127 either p-nitrophenyl phosphate (pNPP) or 32P-myelin basic protein (MBP) as substrates, with matching

128 Here we show that myelin basic protein (MBP) binds to L1 in a Lewis(x)-dep

129 with Tbeta4 demonstrated an amplification of myelin basic protein (MBP) expression and differentiatio

130 znf16l mutant larvae have reduced myelin basic protein (mbp) expression and reduced CNS my

131 counterparts, achieving widespread and dense myelin basic protein (MBP) expression by 4 weeks after g

132 tion, we performed an image-based screen for myelin basic protein (MBP) expression using primary rat

133 Mice are immunized with myelin basic protein (MBP) for induction of disease.

134 unohistochemically subsets of astrocytes and myelin basic protein (MBP) from selected regions of huma

135 The myelin basic protein (MBP) gene encodes two families of

136 The myelin basic protein (MBP) gene encodes two families of

137 days after birth) promotes activation of the myelin basic protein (Mbp) gene with an accelerated loss

138 A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determin

139 1-129 represent an immunodominant epitope of myelin basic protein (MBP) in humans with human leukocyt

140 cytokine profile and the T-cell responses to myelin basic protein (MBP) in the reconstituted immune s

141 ce of myelin at various surface coverages of myelin basic protein (MBP) indicate that maximum adhesio

142 Myelin basic protein (MBP) is a major candidate autoanti

143 Myelin basic protein (MBP) is a major component of centr

144 We previously reported that myelin basic protein (MBP) is a potent inhibitor of Abet

145 The N-terminal epitope of myelin basic protein (MBP) is immunodominant in this mod

146 Myelin basic protein (MBP) is the major structural prote

147 We screened for myelin basic protein (mbp) mRNA by in situ hybridization

148 ertheless fail to localize normal amounts of myelin basic protein (mbp) mRNA in cellular processes, a

149 RNA trafficking factor that associates with myelin basic protein (MBP) mRNA.

150 ligodendrocyte-specific mRNAs, including the myelin basic protein (MBP) mRNA.

151 was verified by decreased immunostaining of myelin basic protein (MBP) on P9.

152 s of lipid composition and concentrations of myelin basic protein (MBP) on the structure of model lip

153 genic T cell receptor (TCR) specific for the Myelin Basic Protein (MBP) peptide Ac1-9, making the ani

154 E suppressed EAE when disease was induced by myelin basic protein (MBP) peptide or encephalitogenic T

155 acked myelin membranes, mostly occupied by a myelin basic protein (MBP) phase.

156 Myelin basic protein (MBP) plays an important structural

157 Interestingly, after myelin basic protein (MBP) priming, the expression of Fo

158 hat the overexpression of p27(Kip1) enhances myelin basic protein (MBP) promoter activity.

159 these transgenic pMBP-eGFP-NTR tadpoles the myelin basic protein (MBP) regulatory sequences, specifi

160 In this study, euthymic myelin basic protein (MBP) TCR transgenic mice are prote

161 A reduction in the net positive charge of myelin basic protein (MBP) via deimination of arginine t

162 Our previous studies determined that myelin basic protein (MBP) was capable of inhibiting fib

163 We show that MHC class I-restricted myelin basic protein (MBP) was presented by oligodendroc

164 ells are specific for the Ac1-11 fragment of myelin basic protein (MBP) with Ac1-11 elicits T cells w

165 tiation of OPs into oligodendrocytes forming myelin basic protein (MBP)(+) and proteolipid protein-po

166 e T cells of CD4 and CD8 subsets recognizing myelin basic protein (MBP), a candidate myelin autoantig

167 ss I-restricted T cells specific for classic myelin basic protein (MBP), a component of the myelin sh

168 r data further reveal that the expression of myelin basic protein (MBP), a myelin-specific protein th

169 ion (ECi) with the immunodominant peptide of myelin basic protein (MBP), Ac1-11, protects mice that a

170 the N-terminal autoantigenic determinant of myelin basic protein (MBP), Ac1-9, is dominant in the B1

171 ctivity in vitro, including the breakdown of myelin basic protein (MBP), and that K6-immunized mice e

172 gulates translation of a key sheath protein, myelin basic protein (MBP), by reversing the inhibitory

173 aused abnormalities in the charge pattern of myelin basic protein (MBP), changes linked to adaptive i

174 In multiple sclerosis (MS), myelin basic protein (MBP), critical for the maintenance

175 A critical component of myelin is myelin basic protein (MBP), expression of which requires

176 L-6; glial fibrillary acidic protein (GFAP), myelin basic protein (MBP), interferon gamma (IFNgamma),

177 of the myelin multilayered membrane sheath, myelin basic protein (MBP), is hydrolyzed by the 26S pro

178 Seven days after immunization with myelin basic protein (MBP), mice received MBP-specific t

179 h as glial fibrillary acidic protein (GFAP), myelin basic protein (MBP), or F4/80 as determined by We

180 mmune encephalomyelitis by immunization with myelin basic protein (MBP), or MBP68-86, the dominant en

181 9 peptide, the immunodominant determinant of myelin basic protein (MBP), produced a single episode of

182 rations of neurofilament light chain (NF-L), myelin basic protein (MBP), S100B, and heart-type fatty

183 structural proteins, including that for the myelin basic protein (MBP), until postnatal day 13 (P13)

184 s and in the central nervous system (CNS) of myelin basic protein (MBP)-induced EAE mice, especially

185 by O1 antibodies and subsequently mature to myelin basic protein (MBP)-positive cells prior to forma

186 mature oligodendrocytes and weakly in mature myelin basic protein (MBP)-positive oligodendrocytes.

187 Myelin basic protein (MBP)-primed T cells alone induced

188 Interestingly, we found that myelin basic protein (MBP)-primed T cells from female an

189 dy was undertaken to investigate the role of myelin basic protein (MBP)-primed T cells in the express

190 Earlier we have demonstrated that myelin basic protein (MBP)-primed T cells induce the exp

191 o investigate the activation of microglia by myelin basic protein (MBP)-primed T cells of male, femal

192 Ob1A12 is a myelin basic protein (MBP)-reactive Th cell clone derive

193 del of spontaneous EAE, we demonstrated that myelin basic protein (MBP)-specific CD4(+) T cells up-re

194 Here we found that CD8(+) myelin basic protein (MBP)-specific T cell tolerance was

195 Myelin basic protein (MBP)-specific T cells are thought

196 or multiple sclerosis induced by stimulating myelin basic protein (MBP)-specific T cells.

197 ctively redirect therapeutic T cells against myelin basic protein (MBP)-specific T lymphocytes implic

198 uble peptide induces peripheral tolerance in myelin basic protein (MBP)-specific TCR transgenic mice.

199 Classical EAE spontaneously occurs in myelin basic protein (MBP)-specific TCR transgenic RAG-1

200 genes such as myelin protein zero (MPZ) and myelin basic protein (MBP).

201 in T cell tolerance to myelin proteins like myelin basic protein (MBP).

202 T cells specific for myelin proteins such as myelin basic protein (MBP).

203 cell repertoire biased toward recognition of myelin basic protein (MBP).

204 s to central nervous system antigens such as myelin basic protein (MBP).

205 to each molecule of its preferred substrate, myelin basic protein (MBP).

206 tively interacted with the mRNA encoding the myelin basic protein (MBP).

207 dicated by reduced immunostaining for O4 and myelin basic protein (MBP).

208 1alpha KO mice, accompanied by a decrease in myelin basic protein (MBP).

209 are antigen-specifically redirected against myelin basic protein (MBP)89-101-specific autoreactive T

210 An identical sequence was found in both myelin basic protein (MBP, residues 96-102), a candidate

211 the frequencies and functional avidities of myelin basic protein (MBP:87-99)-specific CD4 cells in S

212 s differentially expressed in schizophrenia (myelin basic protein [MBP], myelin-oligodendrocyte glyco

213 tions in the lipid and the adhesive protein (myelin basic protein, MBP) composition.

214 f1b is required for the localization of mbp (myelin basic protein) mRNA to processes of myelinating o

215 ing the expression of myelin-specific genes (myelin basic protein, myelin oligodendrocyte glycoprotei

216 several myelin-associated proteins including myelin basic protein, myelin proteolipid protein, and 2'

217 ons to injury, we examined the expression of myelin basic protein, Na(v)1.2, Na(v)1.6, NCX and beta-a

218 or marker(+)), and terminal-differentiation (myelin basic protein(+)) of OPs was significantly increa

219 ed serum neuron-specific enolase, S100b, and myelin basic protein on days 1-4 and 7 after cardiac arr

220 Immunostaining of myelin basic protein on paraffin sections derived from 1

221 ells were unable to counter EAE induced by a myelin basic protein or a myelin oligodendrocyte glycopr

222 Nor was it able to methylate myelin basic protein or histone H2A, in vitro substrates

223 for antibodies to candidate antigens such as myelin basic protein or myelin-oligodendrocyte glycoprot

224 y proteins chondroitin sulfate proteoglycan, myelin basic protein, or Nogo-A (reticulon 4).

225 ther IFN-gamma- or IL-17-skewed responses to myelin basic protein over the course of a year.

226 301 or DR1301) and block the presentation of myelin basic protein peptide 152-165 (MBP 152-165) to T

227 ype (Esr1(+/+)) controls when immunized with myelin basic protein peptide Ac1-11 (MBP(Ac1-11)).

228 nsgenic T-cell receptor that is specific for myelin basic protein peptide Ac1-9 (ASQKRPSQR).

229 TCR) transgenic mouse model specific for the myelin basic protein peptide Ac1-9.

230 oth myelin oligodendrocyte glycoprotein- and myelin basic protein peptide-induced EAE.

231 ificant decreases in the mean (SD) number of myelin basic protein peptide-specific cells secreting IL

232 Mean (SD) number of myelin basic protein peptide-specific cells secreting in

233 (TCR) that recognizes two I-A(u)-restricted myelin basic protein peptides and one of its peptide/maj

234 , and only when specifically stimulated with myelin basic protein, peripheral blood mononuclear cell

235 or they can be terminally differentiated to myelin basic protein-positive (MBP(+)) oligodendrocytes.

236 tal segment of optic nerve whereas decreased myelin basic protein-positive axon counts were seen in a

237 2+, Myelin Associated Glycoprotein-positive, Myelin Basic Protein-positive oligodendrocytes, rather t

238 tely resected JPAs suggests that JPA without myelin basic protein-positively stained tumor cells may

239 Similarly, treatment of myelin basic protein-primed SJL/J lymph node cells with

240 enocytes from collagen-primed DBA/1 mice and myelin basic protein-primed SJL/J mice with Ag in the pr

241 ved that NaB switched the differentiation of myelin basic protein-primed T cells from Th1 to Th2 mode

242 n cells, we cloned and characterized the rat myelin basic protein promoter by a genome walking techni

243 ith a luciferase reporter gene driven by the myelin basic protein promoter define how changes in the

244 The amplified rat myelin basic protein promoter was cloned into a lucifera

245 Two regulatory elements in the myelin basic protein promoter were identified and found

246 he transcriptional activator Puralpha to the myelin basic protein promoter.

247 h) alpha-syn under the control of the murine myelin basic protein promoter.

248 histone deacetylase 1-mSin3A complex to the myelin basic protein promoter.

249 ved in the Nkx2.2-mediated repression of the myelin basic protein promoter.

250 ts OPC lineage progression and inhibits MBP (myelin basic protein) promoter activity and Sox10 functi

251 ion experiments show that both mouse and rat myelin basic protein promoters yield increased expressio

252 exhaustively assayed for reactivity against myelin basic protein, proteolipid protein, and myelin ol

253 e data, myelin protein expression, including myelin basic protein, proteolipid protein, myelin oligod

254 ed to the well-characterized myelin antigens myelin basic protein, proteolipid protein, or myelin oli

255 ephalomyelitis of SJL mice induced by MP4, a myelin basic protein-proteolipid protein (PLP) fusion pr

256 ted between phosphorylated neurofilament and myelin basic protein (r = 0.58, P < 0.01), myelin basic

257 ll lines had marked inhibition on autologous myelin basic protein-reactive T cells and displayed two

258 from the TCR and are expressed by expanding myelin basic protein-reactive T cells mediating experime

259 ived immunization with irradiated autologous myelin basic protein-reactive T cells.

260 We assayed the myelin basic protein-reactive TCR repertoire in naive, E

261 ults in apoptotic depletion of the dominant, myelin basic protein-reactive V beta 8.2(+) T cells, but

262 nal density, intensity of immunostaining for myelin basic protein (reflecting myelin content) and pho

263 log peptides of an immunodominant epitope of myelin basic protein (residues 83-99) with alanine subst

264 nRNP A2) that mediate dendritic targeting of myelin basic protein RNA by the A2 pathway in oligodendr

265 avorable outcome and survival, whereas serum myelin basic protein's best accuracy occurred at 48 hour

266 ed axonal vulnerability in mice deficient in myelin basic protein (shiverer), also expressing yellow

267 Myelin basic protein-specific CD8(+) T cells can induce

268 the first in clearly elucidating the fate of myelin basic protein-specific encephalitogenic T cells i

269 e in regulatory T cells, with an increase in myelin basic protein-specific T cell proliferation and s

270 eptides inhibited the encephalitogenicity of myelin basic protein-specific T cells.

271 s IL-17 in the CNS as well as suppression of myelin basic protein-specific Th1 autoreactive T cells.

272 Lgals9 mutant (Gal-9(-/-)) mice as well as a myelin basic protein-specific Tim-3(+) encephalitogenic

273 ressing a transgenic T cell receptor against myelin basic protein spontaneously develop experimental

274 ereby increasing oligodendrocyte density and myelin basic protein staining in CNS lesions.

275 (24 h), and their brains were processed for myelin basic protein staining.

276 ramatic reduction in transphosphorylation of myelin basic protein substrate.

277 was no change in PP1 activity measured using myelin basic protein, suggesting that PTG overexpression

278 in affected individuals from one family lack myelin basic protein, suggesting that this disease in af

279 ells appeared to mediate the effect: an anti-myelin basic protein T-cell line treated with cefuroxime

280 d experimental allergic encephalomyelitis in myelin basic protein-T cell receptor transgenic mice, su

281 experimental autoimmune encephalomyelitis in myelin basic protein TCR transgenic mice, and showed tha

282 fusions containing the N-terminal epitope of myelin basic protein that is associated with experimenta

283 ong-Evans shaker (les) rat has a mutation in myelin basic protein that results in severe CNS dysmyeli

284 s of the major protein in the myelin sheath, myelin basic protein, through Fyn kinase-dependent signa

285 ferent antigens, such as phosphatidylserine, myelin basic protein, thyroglobulin, histone, insulin, c

286 s signalling stimulates local translation of myelin basic protein to initiate myelination.

287 in OLGs stimulates CREB phosphorylation and myelin basic protein transcription and increases surviva

288 The change in charge of the myelin basic protein upon phosphorylation by the protein

289 pecific autoimmunity, oral tolerization with myelin basic protein was abrogated as well in Grail(-/-)

290 -term outcome, whereas greater reactivity to myelin basic protein was correlated with stroke severity

291 Myelin basic protein was identified as a major citrullin

292 Expression of myelin basic protein was increased, and activity of MMP-

293 Myelin basic protein was significantly reduced in all re

294 al staining for protein gene product 9.5 and myelin basic protein was used to evaluate morphological

295 primary cultures of mature OLs that express myelin basic protein, we found that 3-morpholinosydnonim

296 elin deficiency and diminished expression of myelin basic protein were noted in GBDK brains.

297 ligodendrocytes and their ability to produce myelin basic protein were significantly decreased.

298 Myelin basic protein, when added to the CYT monolayer, i

299 transcriptional control of the promoter for myelin basic protein, which is oligodendrocyte-specific.

300 EAE was induced in rats using a fragment of myelin basic protein, yielding acute clinical disease th