コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 ighted by MR relaxation rates (influenced by myelination).
2 ors and G protein-coupled receptors, control myelination.
3 nds SC precursor pools and blocks peripheral myelination.
4 endent changes in neurovascular coupling and myelination.
5 ORC1 function in Schwann cells (SCs) hampers myelination.
6 ) signaling in regulating distinct stages of myelination.
7 ligodendrocyte process extension and thereby myelination.
8 ajor feature of normal brain development and myelination.
9 n potentials, and that such process promotes myelination.
10 oligodendrocyte morphology and capacity for myelination.
11 e essential for proper nerve development and myelination.
12 differentiation and subsequent initiation of myelination.
13 ial pathogenic mechanism because it inhibits myelination.
14 is potentially important for promoting axon myelination.
15 eneration, tumorigenesis, and suppression of myelination.
16 g to ensure the correct timing and amount of myelination.
17 tion neither impaired myelin nor reactivated myelination.
18 predict lncRNA functions in oligodendrocyte myelination.
19 has an essential role in the early events of myelination.
20 iously unknown role for the Hippo pathway in myelination.
21 e that Kif13b is a negative regulator of CNS myelination.
22 e development of mature oligodendrocytes and myelination.
23 arget of rapamycin (mTOR), a major driver of myelination.
24 le of QKI in oligodendrocyte development and myelination.
25 cells, enhances AKT activation and promotes myelination.
26 ion arrest and apoptosis, and failure of CNS myelination.
27 ion regulators in cooperation with SOX10 for myelination.
28 ritic cue is necessary to prevent non-axonal myelination.
29 y for radial sorting of axons and subsequent myelination.
30 at Akt controls several key steps of the PNS myelination.
31 ntials from the eye to the SC due to lack of myelination.
32 ligodendroglial cells is critical for normal myelination.
33 pression during Schwann cell development and myelination.
34 promoting myelin growth during developmental myelination.
35 uding brain development, synaptogenesis, and myelination.
36 ndifferentiated SCs incompatible with normal myelination.
37 PI3K/Akt/mTOR pathway, a powerful driver of myelination.
38 exquisite examples of membrane remodeling is myelination.
39 otransmitter release into activity-dependent myelination.
40 pathways involved in regenerative process of myelination.
41 equired in neurons and in OLs for normal CNS myelination.
42 d by L-VOCCs in OPCs is necessary for normal myelination.
43 ition, chromatin reorganization and impaired myelination.
44 g postnatal days 0-4 (P0-P4), preceding most myelination.
45 rucial role in radial axonal sorting and PNS myelination.
46 ecruits and cooperates with Sox10 to promote myelination.
47 sion levels and properties may change during myelination.
48 Sip1), is essential for differentiation and myelination.
49 ystem (PNS) and central nervous system (CNS) myelination.
50 ells, but not in neurons, is detrimental for myelination.
51 l as promoted oligodendrocyte maturation and myelination.
52 6/Adgrg6 is essential for SC development and myelination.
53 monstrated that electrical activity promotes myelination.
54 growth, lung maturation and brain growth and myelination.
55 ation in neural features like morphology and myelination.
56 on in the presence of complement, and impair myelination.
57 known to regulate key aspects of peripheral myelination.
58 CL4 is necessary for proper peripheral nerve myelination.
59 e differentiation and central nervous system myelination.
60 on.Axon-glial communication is important for myelination.
61 involved in peripheral nervous system (PNS) myelination.
62 4,5)P3 is sufficient to trigger all steps of myelination.
63 mote oligodendrocyte differentiation and (re)myelination.
64 gy, reduces axon-OL interactions and impairs myelination.
65 phasize the essential role lysosomes play in myelination.
66 f Krox20 (Egr2), the master regulator of PNS myelination.
67 ize that Shp2 is a negative regulator of CNS myelination.
68 godendrocyte lineage specification and nerve myelination.
69 A) activation, which is required to initiate myelination.
70 growth overcoming signals that normally end myelination.
71 odendrocytes, may lastingly disrupt cortical myelination, a fundamental feature of cerebral connectiv
72 In the present study, we investigated how myelination affects ion channel expression and function,
75 fluorescent fusion protein reporter to study myelination along the axons of distinct neuronal subtype
76 promoting rapid, efficient nerve conduction, myelination also made possible the development of the la
77 failure, accumulating evidence suggests that myelination also regulates the structural properties and
81 ure work to investigate how these changes in myelination and conduction velocity contribute to signal
82 ied depending on activity levels, and axonal myelination and conduction velocity exhibited no adaptat
83 e observed upregulation of genes involved in myelination and downregulation of genes related to memor
84 ficiently to accelerate axonal regeneration, myelination and function are restored after injury.SIGNI
86 anscriptional regulation at the inception of myelination and implicate abnormal timing of myelination
87 niques allowing us to quantify the degree of myelination and iron accumulation via markers of tissue
88 The MAPK/ERK pathway promotes developmental myelination and its sustained activation in SCs induced
91 demonstrates that GlcNAc6ST-1 modulates PNS myelination and myelinated axonal survival through the G
93 ss and IVH-induced inflammation and restores myelination and neurologic recovery in preterm rabbits w
94 ibition by intramuscular perampanel restored myelination and neurologic recovery in rabbits with IVH.
95 ation, promotes OPC maturation, and restores myelination and neurological function in rabbits with IV
96 e show the relationship between cholesterol, myelination and neurological parameters in mouse models
97 m-based strategies that effectively enhanced myelination and neurological recovery in preterm rabbit
98 treatment reduced inflammation and enhanced myelination and neurological recovery in rabbits with IV
99 has a low side-effect profile, also enhances myelination and neurological recovery in rabbits with IV
100 from vertebrate Schwann cells causes loss of myelination and neuropathies, results attributed to loss
101 MII) enhances central but impairs peripheral myelination and NMII has been implicated in cellular res
105 ght into the signaling mechanisms regulating myelination and propose that Shp2 acts as a transient br
110 ice cultures, Treg accelerated developmental myelination and remyelination, even in the absence of ov
113 TSC has different functions in developmental myelination and remyelination.SIGNIFICANCE STATEMENT Mye
115 h, our findings suggest that BACE1's role in myelination and some sensorimotor functions is consisten
116 omatodendritic compartment directly inhibits myelination and suggest a model in which broadly indiscr
117 nal neurobiological modifications, including myelination and synapse formation, but also pruning of a
119 spatial correspondence between the degree of myelination and the strength of the tonotopic signal acr
120 strong concordance in the degree of cortical myelination and the strength of tonotopic activation acr
121 erstanding of how different neurons regulate myelination and thus their own function within specific
122 mical network had greater rates of shrinkage/myelination and were associated with overexpression of t
123 sal agenesis and pontine hypoplasia, delayed myelination and, less frequently, thalamic signal intens
124 ly and negatively impacts programs governing myelination, and acts on myelinating oligodendrocyte (OL
125 godendrocyte count and decreased spinal cord myelination, and display related neurological phenotypes
127 es inflammation and restores OPC maturation, myelination, and neurologic recovery in preterm newborns
128 administration would restore OPC maturation, myelination, and neurological function in survivors with
130 -independent and activity-dependent modes of myelination are beginning to crystallize in a model of m
131 e statement: Oligodendrocyte development and myelination are highly dynamic processes influenced by e
133 ligodendrocyte precursor cells, and promotes myelination as well as clinical recovery in preterm rabb
136 ter demyelination, are suitable for in vitro myelination assays, disease modeling, and screening of p
137 we show that, despite a developmental delay, myelination at the onset and during cuprizone-induced de
138 he function and maturation of OLs to promote myelination.Axon-glial communication is important for my
139 ndrocyte progenitor cell differentiation and myelination both in vitro and after transplantation into
140 iator of oligodendrocyte differentiation and myelination, both during developmental myelination as we
142 in oligodendrocyte differentiation and early myelination, but is not necessary for myelin maintenance
143 ndrocyte differentiation, and viability, and myelination, but their mechanisms of action are incomple
144 +) channels (VGCCs) are important for normal myelination by acting at several critical steps during o
145 ], but it is not known whether regulation of myelination by activity is common to all neuronal subtyp
148 One possibility is that cholesterol promotes myelination by facilitating signal transduction within t
149 Whereas regulation of central nervous system myelination by GPR17 is well established, verification o
153 in Schwann cells Kif13b positively regulates myelination by promoting p38gamma mitogen-activated prot
154 e that while some neuronal subtypes modulate myelination by synaptic vesicle release to a striking de
155 y aspects of oligodendrocyte development and myelination can be modulated by extrinsic signals includ
159 xpectedly opened new avenues of insight into myelination-centered mechanisms of neural plasticity.
160 saccharide reduced inflammation and enhanced myelination, conceivably by depleting HC-HA levels.
170 restricted solely to Schwann cells reversed myelination defects, significantly improved neuromuscula
172 del displays not only axonal damage but also myelination deficits and glial activation in different b
173 Kernicterus presents as axonopathy with myelination deficits at different brain regions, includi
175 ur data indicate that Akt is crucial for PNS myelination driving axonal wrapping by unmyelinated and
176 ed thin myelin sheaths in a model of delayed myelination during a period of 13 years that we propose
177 ensure the correct onset and progression of myelination during both development and following periph
180 nsensus that neuronal activity regulates CNS myelination (e.g., [5-9]) through local axon-oligodendro
185 serine/threonine kinase Akt in promoting CNS myelination has been demonstrated, its role in the PNS h
186 to increasing the speed of nerve conduction, myelination has emerged as a source of plasticity in neu
187 ificant enrichment for genes associated with myelination, hormone stimulus, and abnormal hormone leve
188 though nodal proteins cluster in response to myelination, how myelin-forming glia influence nodal ass
189 esis, resulted in significantly retarded CNS myelination; however, myelin appeared normal at 3 months
191 lum was the area most affected, with greater myelination impairment and glia burden, and showing a ma
192 measure cortical thickness and intracortical myelination in 297 population volunteers aged 14-24 y ol
195 isingly, the phenotypes ranged from arrested myelination in nerve development to focal hypermyelinati
198 elopment, with less coherent fibers and less myelination in SCR and PCR only in male infants, but the
199 2 (JAM2) as an inhibitor of somatodendritic myelination in spinal cord neurons, thereby elucidating
202 myelination and implicate abnormal timing of myelination in the pathogenesis of childhood-onset dysto
203 ce, sustained Sox2 expression in vivo blocks myelination in the peripheral nerves and maintains Schwa
205 NRG1) is a key signalling factor controlling myelination in the peripheral nervous system, via signal
212 enhance oligodendrocyte differentiation and myelination in vitro, for 2 weeks in adult mice followin
215 as a physiological regulator of Schwann cell myelination in vivo and its potential to play a role in
216 wished to test fully whether Sox2 regulates myelination in vivo and show here that, in mice, sustain
218 ized by clustering of activated MG, aberrant myelination, increased inflammation, and lysosomal anoma
226 d axons following injury and we show that re-myelination is also blocked by Sox2 expression in Schwan
229 t that this activity-dependent alteration of myelination is important for modifying the conductive pr
233 gest a model in which broadly indiscriminate myelination is tailored by inhibitory signaling to meet
236 ure OLs in the adult mouse CNS to reinitiate myelination, leading to new myelin wraps and functional
238 es designed to push mature OLs to reinitiate myelination may be beneficial both for enhancing remyeli
239 on for binaural auditory processing, reduced myelination might augment sensorineural hearing impairme
240 f ASO treatment after disease onset restored myelination, MNCV, and CMAP almost to levels seen in WT
241 e current study suggests that changes in CNS myelination occur as a downstream mechanism following pe
243 cells (NG2 cells) could be key to rendering myelination of axons dependent on neuronal activity, but
250 tivity in the transgenic mice did not induce myelination of nonmyelinating Schwann cells in the sympa
252 role that it plays in these cells and in the myelination of the peripheral nervous system (PNS) is un
253 defeat induces molecular changes that reduce myelination of the prefrontal cortex, which may be an un
254 y chemical cross-linking results in aberrant myelination of the somatodendritic compartment of neuron
255 ants leads to cerebral inflammation, reduced myelination of the white matter, and neurological defici
257 ulation of a gene set enriched for decreased myelination, oligodendrocyte differentiation, and expres
258 opmental oligodendrocyte differentiation and myelination, oligodendrocyte-specific deletion of tubero
259 However, if mTORC1 was hyperactivated after myelination onset, radial hypermyelination was observed.
260 upregulation commenced during developmental myelination or was induced later during adulthood in qui
264 es in type IIb FCD are due to defects of the myelination processes and maturation, impaired by the pr
265 l blockade of the NRG1-ErbB pathway prevents myelination, providing direct evidence for the ability o
266 ought to be more sensitive to differences in myelination (putatively indexed by the [quantitative] lo
267 mpromising axonal fiber number, density, and myelination, rather than processes leading to spatial di
271 concept has emerged that activity-regulated myelination represents an important form of nervous syst
272 chwann cell development and peripheral nerve myelination require the serial expression of transcripti
276 ental process of synaptic pruning and limits myelination, resulting in age-specific reductions in cor
277 uberty followed by selective elimination and myelination, resulting in volume loss and thinning.
280 ed for Schwann cell (SC) differentiation and myelination; sustained embryonic MAPK/ERK activation in
281 ted with oligodendrocyte differentiation and myelination that were validated via cross-species compar
283 ER stress, suggesting that Perk may modulate myelination through a pathway independent of the UPR.
284 ffectors TAZ and YAP in SC proliferation and myelination through modulating G-protein expression and
285 cline in mTORC1 activity is crucial to allow myelination to start, while remaining mTORC1 activity dr
286 inic compound that has been shown to enhance myelination under demyelinating conditions, successfully
287 muli on mechanisms governing programs of CNS myelination under normal and pathological conditions.
288 ole of the MAPK/ERK pathway in developmental myelination versus remyelination and the importance of s
289 chwann cells that regulates peripheral nerve myelination via its cognate receptor ADAM22 expressed by
293 s involved in oligodendrocyte maturation and myelination, we used a conditional knock-out mouse for v
295 d in vitro, and the patterning and extent of myelination were perturbed in the CNS of p35(-/-) mice.
296 on of Discs large 1 (Dlg1), a known brake on myelination, which downregulates the phosphatidylinosito
297 e a molecular model for MDL formation during myelination, which is of importance when understanding m
298 ll-derived sensory neurons strongly enhances myelination, while conversely pharmacological blockade o
299 rain structural measurements implied greater myelination within vmPFC in misophonic individuals.
300 k loss of function in Schwann cells restores myelination without diminishing accumulation of P0 or ma
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。