ライフサイエンスコーパス: myeloid progenitor

1 vents the expansion of Nras(G12D/+) HSCs and myeloid progenitors.

2 rentiation skewing of multipotent and common myeloid progenitors.

3 gh estrogen receptor (ER) alpha signaling in myeloid progenitors.

4 PU.1 and induces malignant reprogramming of myeloid progenitors.

5 gulatory factor (IRF)-4 in GM-CSF-stimulated myeloid progenitors.

6 ctor signaling or increased proliferation in myeloid progenitors.

7 ost related to haematopoietic stem cells and myeloid progenitors.

8 cell virus vectors and assayed the growth of myeloid progenitors.

9 f monocytes over neutrophils at the level of myeloid progenitors.

10 cell progeny concomitant with an increase in myeloid progenitors.

11 d shortly after Setbp1 expression in primary myeloid progenitors.

12 n granulocyte-monocyte progenitors or common myeloid progenitors.

13 d expansion of undifferentiated cells in 32D myeloid progenitors.

14 ation of hematopoietic stem cells (HSCs) and myeloid progenitors.

15 d myeloid-related genes could be detected in myeloid progenitors.

16 d of culture and an additional 2 d to expand myeloid progenitors.

17 not required for the proliferation of early myeloid progenitors.

18 ssential for neutrophil differentiation from myeloid progenitors.

19 confer aberrant self-renewing properties to myeloid progenitors.

20 nditionally deleted Nemo from osteoclast and myeloid progenitors.

21 ocyte precursors and results in depletion of myeloid progenitors.

22 suppressor cells (mMDSC) from human or mouse myeloid progenitors.

23 enitors settling the thymus include lymphoid-myeloid progenitors.

24 escence with concomitant expansion of murine myeloid progenitors.

25 sed sensitivity to DNA damage in bone marrow myeloid progenitors.

26 egulation of PtdIns(3,4,5)P3 signaling in BM myeloid progenitors.

27 matopoietic function of ICL-repair deficient myeloid progenitors.

28 of the entire hematopoietic tree, including myeloid progenitors.

29 yeloid-derived suppressor cells (MDSCs) from myeloid progenitors.

30 row by inducing differentiation of committed myeloid progenitors.

31 ortality, self-renewal, and tumorigenesis in myeloid progenitors.

32 Suppression of myeloid progenitors (6 h) occurs only for DMBA.

33 sult from the endothelial differentiation of myeloid progenitors, a process regulated by tumor necros

34 ependent-1 (Gfi1) loss of function, arrested myeloid progenitors accumulate, whereas terminal granulo

35 Intrinsic genetic factors within myeloid progenitors along with extrinsic factors in the

36 PA re-activated replating activity of common myeloid progenitor and granulocyte macrophage progenitor

37 the progenitor cell defect, restoring common myeloid progenitor and megakaryocytic-erythroid progenit

38 ion and expansion, as well as an increase of myeloid progenitors and a decrease of mature cells.

39 xhibit a decrease in myeloid-biased HSCs and myeloid progenitors and an increase in T cells and lymph

40 of the haematopoietic system, such as common myeloid progenitors and common lymphoid progenitors, inc

41 oter in vitro, and in vivo within both early myeloid progenitors and differentiating neutrophils.

42 d LSCs was most similar to that of committed myeloid progenitors and distinct from HSCs.

43 uction of myeloid lineage precursors (common myeloid progenitors and granulocyte myeloid precursors)

44 on assays and defective in generating common myeloid progenitors and granulocyte-monocyte progenitors

45 ment of myeloid precursors, including common myeloid progenitors and granulocytic-monocytic precursor

46 EBPA overlapped an enhancer active in common myeloid progenitors and influenced its activity.

47 Tumor cells recruit myeloid progenitors and monocytes to the tumor site, whe

48 reactive granulopoiesis," in which committed myeloid progenitors and more primitive progenitors cycle

49 ential onto otherwise committed lymphoid and myeloid progenitors and myeloid effector cells.

50 olon cancers transform the growth of primary myeloid progenitors and of Ba/F3 cells.

51 Furthermore, mouse myeloid progenitors and patient leukemic cells with the

52 Myeloid-derived suppressor cells (MDSCs) are myeloid progenitors and precursors that fail to differen

53 rs when IFN-gamma inhibits the generation of myeloid progenitors and prevents lineage differentiation

54 Sf3b1(K700E) myeloid progenitors and SF3B1-mutant MDS patient samples

55 -derived suppressor cells (MDSCs) arise from myeloid progenitors and suppress both innate and adaptiv

56 hromatin exists in a poised configuration in myeloid progenitors and that this poised chromatin struc

57 ranulocyte macrophage CSF (GM-CSF) to expand myeloid progenitors and their progeny in culture.

58 g the commitment of short-term HSC to common myeloid progenitors and these alterations were predomina

59 Irf8(-/-) common myeloid progenitors and, unexpectedly, Irf8(-/-) ALPs pr

60 Late MDSCs had more immature CD31(+) myeloid progenitors and, when treated ex vivo with granu

61 ing lineage(-)Sca-1(+)c-kit(+) (LSK), common myeloid progenitor, and granulocyte/macrophage progenito

62 ctivation of ERK, excessive proliferation of myeloid progenitors, and consequently an acute myeloprol

63 n of immature lineage-negative cells, common myeloid progenitors, and granulocyte/macrophage progenit

64 icant reduction of HSCs, common lymphoid and myeloid progenitors, and lymphoid cell populations in th

65 human long-term HSC, short-term HSC, common myeloid progenitors, and megakaryocyte-erythrocyte proge

66 rythrocyte progenitors, a decrease in common myeloid progenitors, and reduced beta-catenin signaling

67 onal repressors for the survival of CD11b(+) myeloid progenitors, and then they are required as activ

68 Myeloid progenitors are conditionally immortalized using

69 Yet, Flt3(+)CD150(-) myeloid progenitors are not likely to efficiently traffi

70 ly, both Flt3(+)CD150(-) and Flt3(-)CD150(-) myeloid progenitors are susceptible to Notch1-mediated T

71 an increase in the proportions of committed myeloid progenitors, as determined by colony-forming uni

72 ntributes to HOXB4-mediated expansion in our myeloid progenitor assays.

73 topoiesis and highlights PN as a disorder of myeloid progenitors associated with bone marrow dysfunct

74 to the phenotype, stem cell marker CD34 and myeloid progenitor-associated antigen CD13 were analyzed

75 nt DC development from multiple lymphoid and myeloid progenitors autonomously of cellular context.

76 successful establishment of HCMV latency in myeloid progenitors begins at the point of virus entry.

77 s in acquisition of self-renewal capacity by myeloid progenitors, biased myeloid differentiation, and

78 mpartment, consisting of depletion of common myeloid progenitors but relative sparing of granulocyte-

79 he accumulation and lineage specification of myeloid progenitors, but not terminal granulopoiesis.

80 f normal hematopoiesis, that the loss of MDS myeloid progenitors by programmed cell death and program

81 studies identified autocrine stimulation of myeloid progenitors by Tgfbeta2 as one mechanism by whic

82 Here we show that myeloid progenitors can be derived from embryonic stem c

83 oreover, ectopic miR-223 expression in human myeloid progenitors causes heterochromatic repression of

84 eletion of 2 alleles of p53 rescued both the myeloid progenitor cell and long-term hematopoietic stem

85 y increases atherogenesis through regulating myeloid progenitor cell expansion and differentiation, f

86 n of haematopoietic stem cell/progenitor and myeloid progenitor cell genes.

87 n of KLF7 results in a marked suppression of myeloid progenitor cell growth and a loss of short- and

88 ivation of STAT3-p27(Kip1) pathway in murine myeloid progenitor cell line 32D-G-CSFR cells was marked

89 phages, and ectopic expression of VentX in a myeloid progenitor cell line triggered its differentiati

90 o more pronounced suppression of bone marrow myeloid progenitor cell proliferation and monocytosis, a

91 G-CSF signaling in the regulation of marrow myeloid progenitor cell proliferation in mice with Strep

92 This impairment of myeloid progenitor cell proliferation was not attenuated

93 viral infection using a clonal population of myeloid progenitor cells (Kasumi-3 cells).

94 ation of hematopoietic stem cells (HSCs) and myeloid progenitor cells (MPCs) has been shown to mediat

95 induces a select set of micro-RNAs (miR) in myeloid progenitor cells and AML patients with t(8;21).

96 (MDS) at 24 months of age, with dysplasia of myeloid progenitor cells and anemia with abnormal circul

97 ignaling pathway, we observed an increase in myeloid progenitor cells and CDllb(lo)Gr1(lo) promyelocy

98 expression of HoxA10 is maximal in committed myeloid progenitor cells and decreases as differentiatio

99 GF2 promoter that are activated by HoxA10 in myeloid progenitor cells and differentiating phagocytes.

100 AcmvIL-10 during latent infection of primary myeloid progenitor cells and found that LAcmvIL-10 is re

101 The oncoprotein BCR-ABL transforms myeloid progenitor cells and is responsible for the deve

102 support interleukin-3-independent growth of myeloid progenitor cells and long-term outgrowth of B-ly

103 survival of preleukemic short-term HSCs and myeloid progenitor cells and maintains the differentiati

104 is also expressed during latent infection of myeloid progenitor cells and monocytes and facilitates p

105 OPN (iOPN) diminished the population size of myeloid progenitor cells and myeloid cells, and secreted

106 romoted the outgrowth of Ly6C(+) and Ly6G(+) myeloid progenitor cells and their mobilization to tumor

107 all RNAs, termed microRNAs, encoded by human myeloid progenitor cells are capable of repressing a key

108 tro phenotypes observed with loss of Gfi1 in myeloid progenitor cells but did not rescue Gfi1-/- bloc

109 air of our bones are formed from bone marrow myeloid progenitor cells by a complex differentiation pr

110 interleukin-6 receptor (IL-6R) expression on myeloid progenitor cells by Delta-1 treatment combined w

111 Moreover, murine myeloid progenitor cells carrying an Mll-CBP knock-in al

112 neovasculogenesis and that CD133(+)CXCR4(+) myeloid progenitor cells directly participate in new blo

113 Apc heterozygous myeloid progenitor cells display an increased frequency

114 In contrast, HoxA10-overexpressing myeloid progenitor cells exhibited increased proliferati

115 Consequently, myeloid progenitor cells expressing oncogenic Kras and l

116 d expression of Fap1 and Gas2 in bone marrow myeloid progenitor cells from Icsbp(-/-) mice in compari

117 the phenomenon of microglial augmentation by myeloid progenitor cells in the adult brain.

118 LHRHa), increases the number of lymphoid and myeloid progenitor cells in the bone marrow and developi

119 ncer, we have shown that bone marrow-derived myeloid progenitor cells in the premetastatic lung secre

120 itment of bone marrow-derived CD11b(+)Gr1(+) myeloid progenitor cells in the premetastatic lungs.

121 trafficking was linked to redistribution of myeloid progenitor cells in the spleen.

122 lso determined that HoxA10 overexpression in myeloid progenitor cells increased Tgfbeta2 production b

123 on of the CML-related Bcr-abl oncoprotein in myeloid progenitor cells increases expression of Fas-ass

124 sed Fgf2 production by HoxA10-overexpressing myeloid progenitor cells induced a phosphoinositol 3-kin

125 We determined that expression of Mll-Ell in myeloid progenitor cells resulted in autocrine productio

126 wth factor 2 (Fgf2) by HoxA10-overexpressing myeloid progenitor cells results in activation of beta-c

127 es have relied on ex vivo differentiation of myeloid progenitor cells to DCs in culture.

128 ed that differentiation of latently infected myeloid progenitor cells to dendritic or macrophage-like

129 Mcl1 facilitates AML development by allowing myeloid progenitor cells to evade Myc-induced cell death

130 JMML is acquired hypersensitivity by clonal myeloid progenitor cells to granulocyte macrophage-colon

131 nal activators involved in the commitment of myeloid progenitor cells to the DC lineage and predicted

132 We therefore investigated whether myeloid progenitor cells transformed by Hoxa9 and Meis1

133 and colleagues examine deletion of Dicer1 in myeloid progenitor cells using a conditional Cebpa-Cre a

134 Normal numbers of myeloid progenitor cells were present in Nr4a1-/- mice,

135 marily attributable to autonomous defects in myeloid progenitor cells, although the hematopoietic mic

136 pa was associated with a marked reduction in myeloid progenitor cells, and Gabpalpha null myeloid cel

137 and survival of hematopoietic stem cells and myeloid progenitor cells, and increased Fgf2-expression

138 that HoxA9 repressed ARIH2 transcription in myeloid progenitor cells, antagonizing the effect of Hox

139 ted C57BL/6 mice, we observed a reduction in myeloid progenitor cells, as defined both phenotypically

140 s, we demonstrated that AML EVs are taken-up myeloid progenitor cells, resulting in the selective pro

141 of p53 in limiting aberrant self-renewal of myeloid progenitor cells, such that loss of p53 counters

142 oxidase (MPO), an enzyme found in developing myeloid progenitor cells, the likely origin for myeloid

143 ucing transcription factors IRF8 and PU.1 in myeloid progenitor cells, whereas it reduces G-CSF-drive

144 he gene encoding Fanconi C (Fancc) in murine myeloid progenitor cells.

145 and Ig synthesis, and enhances maturation of myeloid progenitor cells.

146 d a growth advantage over wild-type HOXB4 in myeloid progenitor cells.

147 n of Fap1 with the Apc complex in Bcr-abl(+) myeloid progenitor cells.

148 genes that are activated by beta-catenin in myeloid progenitor cells.

149 gene expression in T cells, mast cells, and myeloid progenitor cells.

150 e properties of the Pu/Gata toggle switch in myeloid progenitor cells.

151 iption factor that is maximally expressed in myeloid progenitor cells.

152 ow previously to inhibit colony formation by myeloid progenitor cells.

153 ormal and transformed hematopoietic stem and myeloid progenitor cells.

154 that Tregs can affect the differentiation of myeloid progenitor cells.

155 ic and carcinogenic species in human CD34(+) myeloid progenitor cells.

156 ed fewer nucleated cells and was enriched in myeloid progenitor cells.

157 e GAS2 promoter and repress transcription in myeloid progenitor cells.

158 iption factor that is maximally expressed in myeloid progenitor cells.

159 g to monocyte/DC lineage commitment of human myeloid progenitor cells.

160 d1 is greater in mature granulocytes than in myeloid progenitor cells.

161 ignancy characterized by clonal expansion of myeloid progenitor cells.

162 vere anemia and thrombocytopenia and expands myeloid-progenitor cells, indicating that FOG-1 is requi

163 y elevated frequencies and numbers of common myeloid progenitor (CMP) and granulocyte/macrophage prog

164 -associated molecular patterns by the common myeloid progenitor (CMP) and is dependent on type I IFN

165 s classical MDS phenotypes and alters common myeloid progenitor (CMP) differentiation by repressing t

166 the developmental defect of DCs from common myeloid progenitor (CMP) in Mysm1(-/-) mice is associate

167 In Dhh-deficient bone marrow, the common myeloid progenitor (CMP) population was increased, but d

168 is associated with an increase in the common myeloid progenitor (CMP) population.

169 ved common lymphoid progenitor (CLP), common myeloid progenitor (CMP), megakaryocyte-erythroid progen

170 tream APC progenitor cells, including common myeloid progenitor (CMP)-Flk2(+).

171 common lymphoid progenitors (CLP) or common myeloid progenitors (CMP) during this process remains el

172 d that induces the differentiation of common myeloid progenitors (CMP) to megakaryocytes.

173 )Sca-1(+)c-Kit(+)CD34(+)Flt3(hi)) and common myeloid progenitors (CMPs) (Lin(-)Sca-1(+)c-Kit(+)CD34(+

174 Herein, we found that common myeloid progenitors (CMPs) and granulocyte-macrophage pr

175 hematopoietic progenitor stem cells, common myeloid progenitors (CMPs) and granulocyte-macrophage pr

176 ther myeloid progenitor compartments [common myeloid progenitors (CMPs) and granulocyte/monocyte prog

177 as an ATM-independent function in the common myeloid progenitors (CMPs) by deletion of Atmin in the e

178 However, unexpectedly, the common myeloid progenitors (CMPs) produce significantly increas

179 Common myeloid progenitors (CMPs) were first identified as prog

180 opulations are thought to derive from common myeloid progenitors (CMPs), and a hierarchical relations

181 ouse hematopoietic stem cells (HSCs), common myeloid progenitors (CMPs), and erythroblasts (ERYs).

182 ) mice revealed that short-term HSCs, common myeloid progenitors (CMPs), erythroid burst-forming unit

183 , common lymphoid progenitors (CLPs), common myeloid progenitors (CMPs), granulocyte/macrophage proge

184 ttern of mutations may differ between common myeloid progenitors (CMPs), granulomonocytic progenitors

185 III-A mRNA transcription increased as common myeloid progenitors committed to become granulocyte-macr

186 -myb inactivation also causes defects in the myeloid progenitor compartment, consisting of depletion

187 A mice in early myeloid development in other myeloid progenitor compartments [common myeloid progenit

188 trophilias by expanding both pluripotent and myeloid progenitor compartments to accelerate granulopoi

189 Bcl3-deficient myeloid progenitors demonstrated an enhanced capacity to

190 Myeloid progenitor-derived suppressor cells (MDSCs) aris

191 loss of in vivo myeloid potential as common myeloid progenitors differentiate into common DC progeni

192 Sustained Runx2 expression hinders myeloid progenitor differentiation capacity and represse

193 We observed inhibition in myeloid progenitor differentiation despite an increase i

194 telomere biology, aberrant RNA splicing, and myeloid progenitor differentiation.

195 ors, which are largely akin to the mammalian myeloid progenitors, display increased levels of ROS und

196 erochronic factor Lin28b decreases in common myeloid progenitors during hematopoietic maturation to a

197 the formation of yolk sac-derived erythroid/myeloid progenitors (EMPs) and hematopoietic stem cells

198 p during organogenesis from yolk-sac erythro-myeloid progenitors (EMPs) distinct from haematopoietic

199 cellular pathway generating Csf1r(+) erythro-myeloid progenitors (EMPs) distinct from HSCs.

200 Both YS MFs and fetal MOs arise from erythro-myeloid progenitors (EMPs) generated in the YS.

201 tion of primitive erythroid cells or erythro-myeloid progenitors (EMPs) in the yolk sac, but it decre

202 bodies, and that these correspond to erythro-myeloid progenitors (EMPs) that first appear in the yolk

203 initive hematopoietic progenitors (erythroid/myeloid progenitors [EMPs]) emerges in the yolk sac begi

204 eased in frequency compared with normal, and myeloid progenitors evade phagocytosis due to up-regulat

205 HoxA10 contributes to myeloid progenitor expansion and differentiation block,

206 ing normal hematopoiesis, HoxA10 facilitates myeloid progenitor expansion and impedes myeloid differe

207 cause hematopoietic stem cell depletion and myeloid progenitor expansion during adult but not fetal

208 oduction in the BM played a critical role in myeloid progenitor expansion during emergency granulopoi

209 etion of Bap1 and Ezh2 in vivo abrogates the myeloid progenitor expansion induced by Bap1 loss alone.

210 a cell line mimicking CP-CML, we found that myeloid progenitor expansion is driven by the exposure o

211 ription factors that direct G-CSF-responsive myeloid progenitor expansion.

212 We showed that GMPs but not common myeloid progenitors expressed low levels of IL-3 recepto

213 enesis proceeds normally but endothelial and myeloid progenitors fail to initiate differentiation, mi

214 In contrast, ectopic expression of NFI-A in myeloid progenitors from NFI-A myeloid cell-deficient mi

215 Myeloid progenitors from patients with heritable and/or

216 In addition, Ercc1-deficient myeloid progenitors gain elevated levels of miR-139-3p a

217 ession with BCR/ABL transforms primary mouse myeloid progenitors, generating aggressive leukemias in

218 Lkb1-deficient HSCs, but not myeloid progenitors, had reduced mitochondrial membrane

219 cells and cardiac valvular tissues leads to myeloid progenitor hyperplasia and pulmonary stenosis du

220 bines cell proliferation as a consequence of myeloid progenitor hypersensitivity to granulocyte-macro

221 nimal region sufficient for MLL-AF6 mediated myeloid progenitor immortalization in vitro and short la

222 on decreased the bone marrow Gr1(+) CD11b(+) myeloid progenitors, improved bacterial clearance, and r

223 Hematopoietic stem cells (HSCs) and myeloid progenitors in MDS have not been extensively cha

224 We report here that erythro-myeloid progenitors in mice generate premacrophages (pMa

225 hanism conferring self-renewal capability to myeloid progenitors in myeloid leukemia development.

226 ensable for growth of normal or K-Ras-mutant myeloid progenitors in response to cytokines.

227 T cells greatly increased the number of the myeloid progenitors in spleen during immune responses.

228 TNF-alpha or IFN-gamma blocked expansion of myeloid progenitors in the bone marrow and also limited

229 athway of human NK cell differentiation from myeloid progenitors in the bone marrow and suggest the u

230 ood, and mutations were observed in HSCs and myeloid progenitors in the bone marrow of 4 patients.

231 essential cross-talk between tumor cells and myeloid progenitors in the bone microenvironment as a re

232 nted the ability of oncogenic JAK2 to expand myeloid progenitors in vitro and in vivo.

233 red STAT3 for cytokine-independent growth of myeloid progenitors in vitro, and mitochondrially restri

234 ficiently confers self-renewal capability to myeloid progenitors in vitro, causing their immortalizat

235 liferative disease in mice, and immortalizes myeloid progenitors in vitro.

236 Setbp1 also promotes self-renewal of myeloid progenitors in vivo as its coexpression with BCR

237 ion Notch1 mutations occurring in developing myeloid progenitors, in addition to known T-lineage prog

238 Here we show that BC CML myeloid progenitors, in particular GMP, serially transpl

239 in hematopoietic cells leads to expansion of myeloid progenitors, increased long-term reconstitution

240 y genes promotes malignant transformation of myeloid progenitors into BC LSCS that are quiescent in t

241 tor (CSF-1R) promotes the differentiation of myeloid progenitors into heterogeneous populations of mo

242 Differentiation of myeloid progenitors into mature myeloid cells requires a

243 y by which Muc1 regulates the development of myeloid progenitors into MDSCs would also be very useful

244 s 1-3 days show increased differentiation of myeloid progenitors into neutrophils and monocytes but r

245 actor; and (iii) directed differentiation of myeloid progenitors into neutrophils, eosinophils, dendr

246 est that miR-29a initiates AML by converting myeloid progenitors into self-renewing LSC.

247 ion of the "don't eat me" signal CD47 on MDS myeloid progenitors is an important transition step lead

248 however, its role in the differentiation of myeloid progenitors is less clear.

249 enomic analysis demonstrates that ERG causes myeloid progenitor leukemia characterized by an inductio

250 uent G-CSF production by ECs is required for myeloid progenitor lineage skewing toward granulocyte-ma

251 cipient's thymus from donor-derived lymphoid-myeloid progenitors (LMPs).

252 Myeloid progenitors lose their potential to generate neu

253 ation in CMML and that GM-CSFR expression on myeloid progenitors may be a biomarker for this therapy.

254 uggest that targeting the differentiation of myeloid progenitors may be a therapeutic strategy for pr

255 We investigated the myeloid progenitor (MP) compartment in KO mice, arguing

256 differentiation of a CD11b(+) DC subset from myeloid progenitors (MPs).

257 RNA depletion affected neither the number of myeloid progenitors nor the percentage of C/EBPA-positiv

258 NOTCH and p38MAPK pathways balance primitive myeloid progenitor output downstream of the BMP pathway.

259 R-125b induces myeloid leukemia by enhancing myeloid progenitor output from stem cells as well as ind

260 actor that is involved in maintenance of the myeloid progenitor population and implicated in myeloid

261 ism by which HoxA10 controls the size of the myeloid progenitor population.

262 be determined earlier than thought and that myeloid progenitor populations are aggregates of individ

263 Here we demonstrated that lympho-myeloid progenitor populations in cord blood - lymphoid-

264 as(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of

265 Mef2c, a transcription factor that promotes myeloid progenitor proliferation, is a target of miR-223

266 Hematopoietic myeloid progenitors released into the circulation are ab

267 Blocking calreticulin on low risk MDS myeloid progenitors rescues them from phagocytosis in vi

268 In vitro, loss of FAK in erythroid and myeloid progenitor's results in impaired cytokine induce

269 AML and, like human LSC, miR-29a-expressing myeloid progenitors serially transplant AML.

270 duction in neutrophil myeloperoxidase to the myeloid progenitors showing down-regulated pu.1 expressi

271 ulations ranging from the oligopotent common myeloid progenitor stage to terminally differentiated ne

272 ion was observed in multipotent progenitors, myeloid progenitors, T-cell progenitors, and B-cell prog

273 d that adult microglia derive from primitive myeloid progenitors that arise before embryonic day 8.

274 sion of functionally enhanced extramedullary myeloid progenitors that correlated with the peripheral

275 irst wave of yolk sac (YS)-derived primitive myeloid progenitors that seed the skin before the onset

276 t Setbp1 led to the immortalization of mouse myeloid progenitors that showed enhanced proliferative c

277 MDSCs are immature myeloid progenitors that suppress T-cell effector functi

278 CD45+ hematopoietic cells highly enriched in myeloid progenitors through coculture of hESCs with OP9

279 Acquisition of self-renewal capability by myeloid progenitors to become leukemic stem cells during

280 ta argue that the differentiation in vivo of myeloid progenitors to circulating DCs promotes the reac

281 his study shows that type I IFN can act upon myeloid progenitors to promote the development of emerge

282 eration, circulation, and homing of lymphoid-myeloid progenitors to the thymus.

283 immune system, including bone-marrow-derived myeloid progenitors, to generate an inflammatory microen

284 ve apoptosis of hematopoietic stem cells and myeloid progenitors, together with elevated DNA damage,

285 ell-produced ROS stimulated proliferation of myeloid progenitors via a paracrine mechanism.

286 n that conferred autonomous proliferation to myeloid progenitors was found.

287 nctions, the production of both lymphoid and myeloid progenitors was impaired in the absence of Atg7.

288 r important for development of erythroid and myeloid progenitors, was one of the most differentially

289 ) Sca-1(-) cells containing primarily common myeloid progenitors were cultured in vitro without or wi

290 previously found that HoxA10-overexpressing myeloid progenitors were hypersensitive to a variety of

291 Therefore, these Flt3(+)CD150(-) myeloid progenitors were T/myeloid potent.

292 The embryonic stem cell-derived myeloid progenitors, when immortalized with estrogen-reg

293 racterized by expansion of phenotypic common myeloid progenitors, whereas higher-risk cases revealed

294 ing factor receptor signaling in bone marrow myeloid progenitors, whereas in platelets cholesterol lo

295 R-139-3p strongly inhibited proliferation of myeloid progenitors, whereas inhibition of miR-139-3p ac

296 nstead established the existence of lymphoid-myeloid progenitors, which possess lymphoid and myeloid

297 Clonal analysis of myeloid progenitors, which produce short-lived granulocy

298 effect by up-regulating the number of common myeloid progenitors while inhibiting development of pre-

299 ls; (ii) short-term expansion of multipotent myeloid progenitors with a high dose of granulocyte-macr

300 Treatment of mouse myeloid progenitors with G-CSF--serum concentrations of