ライフサイエンスコーパス: myeloid suppressor cell

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1 s the development, survival, and function of myeloid suppressor cells.

2 Tumor growth promotes the expansion of myeloid suppressor cells.

3 s combined with a reduction in tumor-induced myeloid suppressor cells.

4 vation of macrophages to function similar to myeloid suppressor cells.

5 ave M1 macrophages and retain high levels of myeloid suppressor cells after surgery; in addition, the

6 revealed CD11b(+)/Gr-1(+) as a heterogeneous myeloid suppressor cell also expressing low levels of MH

7 Tumor stroma is modified, myeloid suppressor cells are reduced, and M1 macrophage

8 mation expands a heterogeneous population of myeloid suppressor cells capable of inhibiting T cell fu

9 We describe that myeloid suppressor cells expressing CD11b(+)/Gr-1(+) mar

10 differentiation and accumulation of immature myeloid suppressor cells (ImC) is one of the major mecha

11 hypothesized causal role for IL-4Ralpha and myeloid suppressor cells in glioma development.

12 eads to a rapid and significant expansion of myeloid suppressor cells in peripheral lymphoid tissues.

13 ffect, we found that a dramatic expansion of myeloid suppressor cells in SHIP(-/-) mice impairs primi

14 creased percentage of regulatory T cells and myeloid suppressor cells in the pancreatic tumor and tum

15 Myeloid suppressor cell-induced immunosuppression is med

16 uitment of immunosuppressive CD11b(+)Gr-1(+) myeloid suppressor cells into the tumor microenvironment

17 ween natural killer (NK) cell activation and myeloid suppressor cell (MSC) expansion in tumor-bearing

18 These myeloid suppressor cells (MSC) are present in many patie

19 ed in regulatory T cells (T(reg)) as well as myeloid suppressor cells (MSC).

20 The accumulation of myeloid suppressor cells (MSCs) is associated with immun

21 Myeloid suppressor cells (MSCs) producing high levels of

22 population of immature myeloid cells, termed myeloid suppressor cells (MSCs), that have potent immuno

23 umors have elevated levels of Gr1(+)CD11b(+) myeloid suppressor cells (MSCs), which inhibit T cell ac

24 TGF-beta, explains previous observations on myeloid suppressor cells or TGF-beta and provides insigh

25 Vascularity and myeloid suppressor cell populations and their regulators

26 ion through effects on tumor vascularity and myeloid suppressor cell populations, in uveal melanoma t

27 goal of this study was to determine whether myeloid suppressor cells producing high arginase existed

28 Depletion of the CD11b+, CD14- myeloid suppressor cells reestablished T cell proliferat

29 Consistent with expansion of myeloid suppressor cells, splenocytes and lymph node cel

30 e this threshold, GM-CSF induced Gr1+/CD11b+ myeloid suppressor cells that substantially impaired ant

31 ma microenvironment of arginase, a marker of myeloid suppressor cells, which is critical for their T-

32 Myeloid suppressor cells with high arginase activity are

33 well as decreased levels of T regulatory and myeloid suppressor cells within the tumor microenvironme

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