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2 pig is associated with hyperexcitability of myenteric AH neurones, enhanced synaptic activity in the
3 o normal levels the electrical properties of myenteric AH neurones, the proportion of S neurones exhi
5 dense mitochondrial network particularly in myenteric AH/Type-II neurons, supporting the importance
8 plexus is an example of differences between myenteric and submucosal components of the enteric nervo
10 t staining with NADPH-diaphorase showed that myenteric and submucosal ganglia formed interconnecting
11 ide increased Fos-LI dose-dependently in the myenteric and submucosal neurons of the duodenum, but no
12 observed within the soma of the majority of myenteric and submucosal neurons, although faint immunor
13 n the number of Fos-immunoreactive nuclei of myenteric and submucosal neurons, following CCK injectio
17 mount preparations of adult (8-12-week old) myenteric and submucosal plexus stained with NADPH diaph
18 vo formed neuroglial structures similar to a myenteric and submucosal plexus, had functional intersti
19 Most of the CRF-IR fibers persisted in the myenteric and submucosal plexuses after 7 days in organo
21 in to colonise the hindgut in large numbers, myenteric and submucosal plexuses in the hindgut almost
22 , the nodose ganglia, and the ganglia of the myenteric and submucosal plexuses of the duodenum follow
23 in morphologically identified neurons in the myenteric and submucosal plexuses of the guinea pig ente
24 d activates the enteric nervous system (ENS; myenteric and submucosal plexuses) of the gastrointestin
26 prominently localized in nerve fibers of the myenteric and submucosal plexuses, muscularis externa an
29 rface of enterochromaffin-like cells, and of myenteric and submucous neurons, and to fibers distribut
39 ERT-immunoreactive terminal axons surrounded myenteric dopaminergic neurons and SERT knock-out increa
40 bmucosal neuron density, and increased colon myenteric fibers per neuron when compared to the wild ty
44 attenuate dorsal vagal complex (DVC) but not myenteric Fos-like immunoreactivity (Fos-LI) induced by
45 ding precursor cells that are located within myenteric ganglia and express both Nestin and p75NTR, bu
46 at ramified extensively through many rows of myenteric ganglia and formed nerve endings in discrete a
47 munoreactivity was observed on nerves within myenteric ganglia and interganglionic fiber tracts throu
50 macaques showed progressive infiltration of myenteric ganglia by CD3+ T cells and IBA1+ macrophages
51 espite an abundance of inflammatory cells in myenteric ganglia during acute infection, the ENS was no
52 luo-4) used to study activity in EGCs within myenteric ganglia during CMMCs, followed by post hoc S10
54 a majority of patients in a HSCR cohort, the myenteric ganglia from the ganglionated region are also
57 uronal cell loss because of apoptosis in the myenteric ganglia of the adult small intestine, total my
58 varicose endings (IGVEs) were identified in myenteric ganglia of the stomach and varicose simple-typ
59 3% of biotinamide-labeled extrinsic axons in myenteric ganglia were labeled by antisera to one of the
62 ssued specialized polymorphic collaterals to myenteric ganglia, and a subset (41%) of antral longitud
63 teric plexus; injections of (125)I-NT-3 into myenteric ganglia, the tertiary plexus, and muscle, labe
73 d complex arbors of varicose neurites within myenteric ganglia/primary plexus and, concomitantly, lon
77 image analysis revealed that the severity of myenteric ganglionitis increased with time after SIV inf
81 Internalization of NK1R was not observed in myenteric ICC or smooth muscle cells in response to nerv
83 incident in subsets of neurons (submucosal > myenteric) in guinea pig and mouse intestines in situ an
84 The high-fat diet induces changes in the myenteric innervation of the small intestine, intestinal
87 of myenteric neurons, as well as in numerous myenteric internodal fibers; immunoreactivity was rarely
89 P(+/-));Foxf2(-/-) mice had expansion of the myenteric nerve plexus and increased proliferation of sm
90 ear inclusions), loss of nerve fibers in the myenteric nerve plexus, and delayed gastrointestinal tra
92 of a high-fat diet (HFD) is associated with myenteric neurodegeneration, which in turn is associated
93 Here we have developed a Swiss-Webster mouse myenteric neuron culture and examined their electrophysi
94 Het)R3(Het)) mutant mice had a reduced colon myenteric neuron density, reduced colon myenteric neuron
97 labeling with antibody markers that identify myenteric neuron subtypes to determine when neuron subty
98 ed a computational model of a Dogiel type II myenteric neuron that successfully reproduces all experi
99 olon myenteric neuron density, reduced colon myenteric neuron to glia ratio, reduced colon submucosal
100 induced diabetic mice, there was evidence of myenteric neuronal apoptosis and reduced Akt phosphoryla
101 Deletion of TPH2, but not TPH1, decreased myenteric neuronal density and proportions of dopaminerg
102 el to compare dorsal vagal complex (DVC) and myenteric neuronal Fos-Like immunoreactivity (Fos-LI), i
104 The electrical and synaptic properties of myenteric neurones in normal and inflamed guinea-pig dis
111 eous intracellular recordings were made from myenteric neurons and circular muscle (CM) cells in isol
113 monstrate the feasibility of isolating mouse myenteric neurons and establish sodium channel inhibitio
114 We evaluated SSTR2A trafficking in murine myenteric neurons and neuroendocrine AtT-20 cells by mic
115 ysiologic, and pharmacologic techniques, the myenteric neurons and neurotransmitters involved in the
118 oxypyruvate altered excitatory properties of myenteric neurons and reduced islet insulin content but
119 ocal microscopy provides detailed imaging of myenteric neurons and smooth muscle cells in the muscula
121 F(2) activation inhibits CRF(1) signaling in myenteric neurons and the stress-induced colonic motor r
122 vestigate the morpho-quantitative aspects of myenteric neurons and the wall of the small intestine in
123 is an autoimmune disease in which esophageal myenteric neurons are attacked in a cell-mediated and an
124 has been demonstrated that subpopulations of myenteric neurons are differentially susceptible to the
127 citatory postsynaptic potentials (fEPSPs) in myenteric neurons but the subunit composition of enteric
128 tion revealed that subsets of submucosal and myenteric neurons contained mRNA encoding D2 or D3.
129 d GLP2 elicit neuroprotective effects on rat myenteric neurons cultured with or without mast cells.
130 so appeared normal in size, but NO-producing myenteric neurons developed very large nuclei as a resul
134 all choline acetyltransferase-immunoreactive myenteric neurons expressed CB(1) receptors in ganglia f
135 rkers were used to identify and characterise myenteric neurons expressing cannabinoid receptors.
136 The neuronal tissue constituted of isolated myenteric neurons from four to 12 days old Wistar rats,
137 re, we used in situ patch-clamp recording of myenteric neurons from mice to define functionally the N
138 GLP1, GLP2 and VIP were added to cultured myenteric neurons from rat small intestine or to co-cult
141 lia cells (EGCs) form a dense network around myenteric neurons in a ganglia and are likely to have no
142 acellular Ca2+ ([Ca2+]i) and excitability of myenteric neurons in guinea pig ileum, using microelectr
143 to determine whether 1) different classes of myenteric neurons in the guinea pig ileum contain muOR i
144 ere made from circular muscle (CM) cells and myenteric neurons in the isolated guinea pig distal colo
147 cetylcholine neurons make up the majority of myenteric neurons in the stomach (70%), they are a minor
150 and/or secretomotor, whereas NT-3-dependent myenteric neurons innervate other myenteric ganglia and/
153 os-LI was then quantified in the DVC and the myenteric neurons of the duodenum and jejunum using a di
154 response to CCK due to increased numbers of myenteric neurons or more intestinal CCK(1) receptors th
155 tonin gene-related peptide (CGRP)-expressing myenteric neurons produce MET, the receptor for hepatocy
156 el Type II/AH sensory neurons and most other myenteric neurons responded to oral elongation with redu
159 te-mapping revealed a small subpopulation of myenteric neurons that appears to express NOS1 only tran
160 essed by neurochemically distinct classes of myenteric neurons that are likely to differ functionally
161 polysaccharide lead to apoptosis in cultured myenteric neurons that express Toll-like receptor 4 (TLR
162 s significant coexpression of NOS and VIP in myenteric neurons that is more prominent in the proximal
163 d of prolonged increases in activity in many myenteric neurons that was correlated to Ca(2+) transien
164 al development of specific nAChR subtypes in myenteric neurons using Wnt1-Cre;R26R-GCaMP3 mice, where
172 t proportions in the small intestine (25% of myenteric neurons were YFP+ at P0 compared to 62% in adu
173 undergoes ligand-induced internalization in myenteric neurons, and (2) the effect of long-term incre
174 ronal cell bodies, to quantify the number of myenteric neurons, and a reverse transcriptase chain pol
175 ndrites, soma, and axons in a small group of myenteric neurons, as well as in numerous myenteric inte
176 was expressed in only a small population of myenteric neurons, but was abundantly expressed in the s
177 ic mice had loss of NADPH diaphorase-stained myenteric neurons, delayed gastric emptying, and increas
178 tivity was found only in approximately 1% of myenteric neurons, extensive OT-immunoreactive varicosit
180 nal subpopulations, particularly cholinergic myenteric neurons, may be more vulnerable than others to
183 DOR localizes specifically to submucosal and myenteric neurons, which might account for the ability o
184 red in all enteric glia and most small bowel myenteric neurons, yet phenotypic effects of Rb1 loss we
203 pression of the hTDP-43 transgene in colonic myenteric plexes resulted in progressive neurodegenerati
204 of neurons projected predominantly to either myenteric plexus ( approximately 13%) or smooth muscle (
205 ely 100% of an arbor's varicose branches) to myenteric plexus ( approximately 2%) or smooth muscle (
208 ctivation of the colonic longitudinal muscle myenteric plexus (LMMP) neurons and localization of CRF(
210 There are considerable differences in the myenteric plexus along different segments of the monkey
213 onged satiety action than CCK-8; and (3) the myenteric plexus and DVC may play roles in these differe
216 ing neural network, exemplified by lack of a myenteric plexus and extensive overgrowth of fibers.
217 nes in the same plexus, from neurones in the myenteric plexus and from sympathetic postganglionic neu
218 nd all layers of the retina) and peripheral (myenteric plexus and innervating nerves) nervous system
219 sensitive, whereas those located within the myenteric plexus are also thought to respond to changes
221 g fast and slow synaptic transmission in the myenteric plexus are organized in a polarity- (ascending
223 Normally, a dominant pacemaker near the myenteric plexus drives slow waves that actively propaga
225 The proportions of CRF-IR cell bodies in the myenteric plexus increased progressively from the stomac
226 e that synaptic facilitation in the inflamed myenteric plexus involves a presynaptic increase in PKA
227 was expressed by enteric glial cells in the myenteric plexus layer, and cultured primary enteric gli
228 (fl/fl); Wnt1Cre+) caused a dramatic loss of myenteric plexus MET-IR neurites and 1-1'-dioctodecyl-3,
229 de synthase (NOS)- and calretinin-containing myenteric plexus neurons and non-cholinergic secretomoto
232 nin gene-related peptide-immunoreactive (IR) myenteric plexus neurons thought to be intrinsic primary
233 ndritic surfaces of neurochemically distinct myenteric plexus neurons, while being on axonal compartm
235 mistry indicated that LAMB4 localizes to the myenteric plexus of colonic tissue and patients harborin
236 opulation of mechanosensory S-neurons in the myenteric plexus of the distal colon which appear to be
241 vity was confined to enteric glia within the myenteric plexus of the mouse colon; the Cx43 inhibitors
247 CRF1 receptor was distributed widely in the myenteric plexus of the stomach and small and large inte
248 n cells with Dogiel type I morphology in the myenteric plexus of the stomach and small and large inte
250 t contribute to synaptic facilitation in the myenteric plexus of the trinitrobenzene sulphonic acid-i
254 ssed survival by counting various genotypes, myenteric plexus presence by acetylcholinesterase staini
255 reatment of opioid naive longitudinal muscle myenteric plexus tissue attenuates PLCbeta3 phosphorylat
256 lation in the guinea pig longitudinal muscle myenteric plexus tissue revealed substantial alterations
258 smural electrical stimuli confirmed that the myenteric plexus was always present and intact in these
259 not express opioids; opioid synthesis in the myenteric plexus was not altered on induction of inflamm
261 that the connectivity between the LM and the myenteric plexus was required for mechanotransduction.
263 removed from progressively longer lengths of myenteric plexus, a graded reduction in the correlation
264 in the postnatal rat gut are located in the myenteric plexus, and shows that these cells can be expa
265 riginates in pacemaker cells surrounding the myenteric plexus, called interstitial cells of Cajal (IC
266 rebral cortex, pituitary, spinal cord, colon myenteric plexus, dorsal root ganglion, and prenatal cor
267 neurones, enhanced synaptic activity in the myenteric plexus, increased serotonin (5-HT) availabilit
268 ng and projection patterns in the guinea pig myenteric plexus, indicate that OFQ-IR is expressed pref
269 ooth muscle, while simultaneously contacting myenteric plexus, is consistent with the view that these
270 the enteric nervous system, specifically the myenteric plexus, of the rhesus monkey (Macaca mulatta)
271 e majority of CM was sharp dissected off the myenteric plexus, ongoing neural activity was absent, or
273 When the LM was sharp dissected off the myenteric plexus, the synchronized discharge of ascendin
274 r Hu was 100% in the P3 and 71% in the adult myenteric plexus, when submucosal neurons were also OTR-
275 ration of a robust expression of DPPX in the myenteric plexus, which strongly reacted with patients'
288 neurons in ganglia of the submucosal but not myenteric plexus; injections of (125)I-NT-3 into myenter
289 mically in neuronal perikarya (submucosal >> myenteric plexus; small intestine > stomach or colon).
291 n, both slow (slow waves, 2-8/min) and fast (myenteric potential oscillations [MPOs]; 16-20/min) elec
293 nicotinic synaptic potentials evoked by the myenteric projections and with noradrenergic IPSPs evoke
294 terstitial cells of Cajal distributed in the myenteric region (ICC-MY) and fibroblast-like cells (FLC
295 neurons, interstitial cells of Cajal in the myenteric region (ICC-MY) and smooth muscle cells during
297 citatory postsynaptic potentials (fEPSPs) in myenteric S neurons were evaluated, and the density of s
298 ly identified a population of mechanosensory myenteric S-interneurons in the distal colon of guinea-p
299 In contrast, when recordings were made from myenteric S-neurons, two distinct electrical patterns of
300 canine colon were pinned with submucosal or myenteric surface uppermost or cut in cross section.
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