ライフサイエンスコーパス: myofibrillogenesis

1 the importance of MRTFs in actin cycling and myofibrillogenesis.

2 triated muscle potentially playing a role in myofibrillogenesis.

3 ted in an inhibition of costamerogenesis and myofibrillogenesis.

4 1, and FMNL2 are required nonredundantly for myofibrillogenesis.

5 localized to the subsarcolemmal space during myofibrillogenesis.

6 keletal myotubes revealed its involvement in myofibrillogenesis.

7 ress a controversy about different models of myofibrillogenesis.

8 ing involvement of the Rho GTPase in cardiac myofibrillogenesis.

9 myocytes (NRC) under conditions that promote myofibrillogenesis.

10 y a role in cytoskeletal organization during myofibrillogenesis.

11 est that LDTs have at least two roles during myofibrillogenesis-activation of sarcoplasmic regulatory

12 Tmod1 nulls results from defects in cardiac myofibrillogenesis and development or from erythroid cel

13 hanically stabilize cells and tissues during myofibrillogenesis and intercalated disc assembly.

14 These studies suggest a role for C3 in myofibrillogenesis and sarcomere remodeling.

15 e a valuable in vivo model for studying both myofibrillogenesis and sarcomere-based cardiac diseases.

16 cyte and matrix fiber alignment and enhances myofibrillogenesis and sarcomeric banding.

17 es of skeletal myotubes to study its role in myofibrillogenesis and the organization of the sarcoplas

18 ick filaments, causing disruption in ordered myofibrillogenesis and/or myofibrillar integrity, and th

19 d1 functions are critical for late stages of myofibrillogenesis, and for the maturation of myofibrils

20 and the role of this pool of the protein in myofibrillogenesis, and implicate the Ozz-E3 ligase in t

21 icular myocytes increase in profile, exhibit myofibrillogenesis, and re-express genes whose expressio

22 f appearance of sarcomeres and MyBP-C during myofibrillogenesis, and the defective formation of sarco

23 Although myofibrillogenesis appeared normal, in knockdown hearts

24 thick filament assembly and many aspects of myofibrillogenesis are independent of the myosin head an

25 We show that both costamerogenesis and myofibrillogenesis are initiated at sites of membrane co

26 myosin head in thick filament formation and myofibrillogenesis by generating transgenic Drosophila l

27 ypothesis that C3 mediates remodeling during myofibrillogenesis, C3 knockout (C3KO) mice were generat

28 5-kDa) proteins that play important roles in myofibrillogenesis, cytoskeletal organization, and cell

29 in leads to Mb-beta-catenin accumulation and myofibrillogenesis defects similar to those observed in

30 vian heart suggesting that the mechanism for myofibrillogenesis differs in cultured and uncultured ce

31 the assembly of sarcomeres, suggesting that myofibrillogenesis does not depend on strong myosin-acti

32 derstanding of the role that MyBP-C plays in myofibrillogenesis during cardiac development and indica

33 earance, srcF527 did not detectably increase myofibrillogenesis either alone or in combination with H

34 Myofibrillogenesis followed, both spatially and temporal

35 Although myofibrillogenesis had occurred, skeletal muscle thin fi

36 ate model for this purpose, we characterized myofibrillogenesis in a developing zebrafish heart and w

37 ping hearts supporting a three-step model of myofibrillogenesis in cardiomyocytes, whether they are p

38 icipating in control of myoblast fusion, and myofibrillogenesis in developing myotubes.

39 n of glycogen in all cell types and abnormal myofibrillogenesis in striated muscle.

40 eveloping muscle cells supports the model of myofibrillogenesis in which assembly begins with premyof

41 Immunofluorescence localization during myofibrillogenesis indicated that the Rho-GEF domain ass

42 n of Golgi components in myogenic cells, and myofibrillogenesis is normal.

43 Although CapZ is crucial for myofibrillogenesis, its role in muscle function and intr

44 While both LDTs and SDTs occur prior to myofibrillogenesis, LDT production ceases and only SDTs

45 itical for nascent myosin folding, promoting myofibrillogenesis, maintaining cytoskeletal integrity a

46 umber of proteins involved in signalling and myofibrillogenesis; mutations in these proteins lead to

47 We report mutations in the myofibrillogenesis regulator 1 (MR-1) gene causing PNKD

48 Myofibrillogenesis requires proper folding and assembly

49 Myofibrillogenesis, the precise assembly of sarcomeric p

50 ease from intracellular stores occurs during myofibrillogenesis, the process of sarcomeric protein as

51 ral aspects of muscle development, including myofibrillogenesis-the terminal differentiation of the s

52 has been proposed to play critical roles in myofibrillogenesis, thin filament length regulation, and

53 In addition, myofibrillogenesis was increased by PGF2 alpha as assess

54 alpha1-Adrenergic receptor agonist-induced myofibrillogenesis was inhibited by some but not all of

55 To address this question of in situ myofibrillogenesis, we applied non-enzymatic procedures

56 gnificance of Tmod1 functions during de novo myofibrillogenesis, we generated Tmod1 null embryonic st

57 to differentiate, both costamerogenesis and myofibrillogenesis were disrupted although the expressio

58 ents, such as beta1D integrin expression and myofibrillogenesis, were suppressed in C3KO myotubes.

59 Q529X-MYPN causes RCM via disturbed myofibrillogenesis, whereas Y20C-MYPN perturbs MYPN nucl

60 for both normal costamerogenesis and normal myofibrillogenesis which are tightly coupled during skel

61 Disturbed myofibrillogenesis with disruption of alpha-actinin2, de

62 yte hypertrophy (ie, increased cell size and myofibrillogenesis, with concurrent transcriptional chan