ライフサイエンスコーパス: myoinositol

1 basal ganglia glutamate and the glial marker myoinositol.

2 ntent compared with animals not infused with myoinositol.

3 lease of osmoregulators, such as taurine and myoinositol.

4 The translated product of accG is related to myoinositol 1 (or 4) monophosphatases from various eucar

5 d SRF, connexin 43 in the cell membrane, and myoinositol 1,4,5-triphosphate receptor in the perinucle

6 Myoinositol 1,4,5-triphosphate receptor inhibition suppr

7 D-Myoinositol 1,4,5-trisphophate 3-kinases (IP(3)-3Ks) pla

8 0.0001) and >3-fold increases in cellular d-myoinositol 1,4,5-trisphosphate (Ins(1,4,5)P3) levels.

9 of a variety of second messengers, including myoinositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)].

10 pathway from glucose 6-phosphate (G 6-P) to myoinositol 1-phosphate (Ins 1-P) and myo-inositol (Ins)

11 ynthesis of myoinositol and the breakdown of myoinositol (1,4,5)trisphosphate, a potent second messen

12 We have studied the expression of 1L-myoinositol-1-phosphate synthase (MIPS; EC 5.5.1.4) in d

13 identify two targets of this modification as myoinositol-1-phosphate synthase and superoxide dismutas

14 also showed enzyme activity on the substrate myoinositol-1-phosphate, indicating that the AtPAP15 is

15 rabidopsis thaliana) recombinant VTC4 with d-myoinositol 3-phosphate (d-Ins 3-P) and l-Gal 1-P.

16 adenophostin A and L-alpha-glycerophospho-D-myoinositol-4,5-bisphosphate (GPIP(2)).

17 Myoinositol alone or myoinositol, betaine, and taurine g

18 iratory amino acids, glycine and serine, and myoinositol also accumulated under drought.

19 d with pro-inflammatory processes, including myoinositol and 1-methyl-histidine, by targeted mass spe

20 Surprisingly, myoinositol and all inositol phosphates tested were perm

21 lite levels in vtc4 mutants showed that less myoinositol and ascorbate accumulate in these mutants.

22 4 is a bifunctional enzyme that impacts both myoinositol and ascorbate synthesis pathways.

23 increasing NAA and glutamate and decreasing myoinositol and choline with age.

24 Concentrations of myoinositol and choline-containing compounds were signif

25 olyzes myoinositol hexakisphosphate to yield myoinositol and free phosphate.

26 nt correlation between levels of glycine and myoinositol and grain yield under drought.

27 ity for the ester conjugates IAA-Glc and IAA-myoinositol and high specificity for the conjugates of i

28 al complexes of the human trimeric NCRD with myoinositol and inositol 1-phosphate showed binding of t

29 gated in symptomatic Alzheimer's disease are myoinositol and N-acetyl-aspartate.

30 a major enzyme required for the synthesis of myoinositol and the breakdown of myoinositol (1,4,5)tris

31 r a combination of dietary dexamethasone and myoinositol and the chemotherapeutic efficacy of Taxol o

32 , interconnected network with mannose (Man), myoinositol, and galacturonic acid as principal entry po

33 h various organic osmolytes, e.g., sorbitol, myoinositol, and glycerolphosphoryl-choline and H(2)O(2)

34 life MetS included citric acid, glucosamine, myoinositol, and proline (P < 0.03).

35 Myoinositol alone or myoinositol, betaine, and taurine given sequentially inc

36 Myoinositol binding occurred in two major orientations,

37 In conclusion, systemic infusion of myoinositol can rapidly increase brain myoinositol conte

38 Brain metabolites (N-acetylaspartate, myoinositol, choline, creatine) were measured bilaterall

39 Brain myoinositol content in animals with uncorrected hyponatr

40 on of myoinositol can rapidly increase brain myoinositol content, but only when plasma tonicity is co

41 Seven SGLT isoforms (SGLT1 to 6 and sodium-myoinositol cotransporter-1, SMIT1) are known, although

42 NAA/Cr ratios decreased and myoinositol/Cr ratios increased with age in RTT patients

43 Decreasing NAA/Cr and increasing myoinositol/Cr with age are suggestive of progressive ax

44 d for creatine, N-acetyl/creatine ratio, and myoinositol/creatine ratio in frontal white matter.

45 Intravenous infusion of myoinositol did not alter brain water content compared w

46 Brain myoinositol, electrolyte, and water contents were determ

47 the cell-impermeable FGF binding antagonist, myoinositol hexakis [dihydrogen phosphate].

48 hat the AtPAP15 is a phytase that hydrolyzes myoinositol hexakisphosphate to yield myoinositol and fr

49 Levels of myoinositol in control conditions were also related to g

50 igated whether administration of intravenous myoinositol in rats could speed entry of the osmolyte in

51 cortex and glial activation (with increased myoinositol) in both frontal gray and white matter.

52 tyl aspartate) and glial dysfunction (higher myoinositol) in multiple brain regions.

53 concurrent infusion of hypertonic saline and myoinositol increased brain myoinositol levels by about

54 concurrent infusion of hypertonic saline and myoinositol increased brain myoinositol to levels simila

55 sorbitol pathway intermediates, depletion of myoinositol, inhibition of glycolysis, a decrease in ATP

56 ulate AsA levels by controlling the input of myoinositol into this branch of AsA biosynthesis in Arab

57 Myoinositol is a known precursor for AsA biosynthesis in

58 uring the production of [(3)H]IP(3) in [(3)H]myoinositol-labeled cells.

59 The even higher myoinositol level in older adults with Down's syndrome e

60 out hypertonic saline did not increase brain myoinositol levels above control levels.

61 ly over the same time period to raise plasma myoinositol levels by 5 to 10 mM.

62 tonic saline and myoinositol increased brain myoinositol levels by about 50% above control levels.

63 e predementia phase earlier findings of high myoinositol levels in symptomatic Alzheimer's disease.

64 Significant decreases (approximately 30%) in myoinositol levels were observed in the right frontal lo

65 ine levels, on frontal gray and white matter myoinositol levels, and on the ratio of myoinositol to c

66 increase in the putative inflammation marker myoinositol (mI) and metabolic changes in total creatine

67 artate (NAA), choline (tCHO), creatine (CR), myoinositol (MI), and glutamate and glutamine (GLX) were

68 N-acetyl aspartate (NAA)/creatine (Cr), NAA/myoinositol (mI), and mI/Cr measured in the posterior ci

69 Myoinositol monophosphatase (IMP) is a major enzyme requ

70 administration on peripheral nerve polyols, myoinositol, Na+/K+ -ATPase, vasoactive prostaglandins,

71 rats, infusion of hypertonic saline without myoinositol or infusion of myoinositol without hypertoni

72 acid (SA)-dependent PCD, revealing roles for myoinositol or inositol derivatives in the regulation of

73 ssed by inositol phosphate turnover in [(3)H]myoinositol organ bath atrial preparations, was not incr

74 a (P < 0.001), brain water (P < 0.05), brain myoinositol (P < 0.001), and urinary phenylacetylglutami

75 rial ammonia and brain water and lower brain myoinositol (P < 0.01, respectively), compared with sham

76 at hydrolyzes 5-phosphates from a variety of myoinositol phosphate (InsP) and phosphoinositide phosph

77 function to the cell death phenotype of the myoinositol phosphate synthase1 (mips1) mutant that form

78 ne, choline, ethanolamine, glucose, lactate, myoinositol, phosphocholine, sylloinositol, and valine s

79 The myoinositol polyphosphate 5-phosphatases (5PTases; EC 3.

80 By labeling the endogenous myoinositol pool in 5ptase1 and 5ptase2 mutants, we dete

81 The myoinositol precursor was prepared from methyl alpha-d-g

82 Brain glutamine/myoinositol ratio was increased in the HD group but redu

83 and a significant increase in potassium and myoinositol release compared with release in hypotonic c

84 d NBD1 stability and aggregation showed that myoinositol stabilized both the Delta F508 and wild type

85 Myoinositol synthesis and catabolism are crucial in many

86 To determine whether the VTC4 gene impacts myoinositol synthesis in Arabidopsis, we isolated T-DNA

87 e key enzyme catalyzing the limiting step of myoinositol synthesis.

88 The myoinositol to creatine ratio was increased in the PPA g

89 tter myoinositol levels, and on the ratio of myoinositol to creatine.

90 tonic saline and myoinositol increased brain myoinositol to levels similar to those found in normonat

91 In some animals, myoinositol was administered intravenously over the same

92 th muscle from six animals preloaded with 3H-myoinositol was exposed to endothelin-1, carbachol (posi

93 ic saline without myoinositol or infusion of myoinositol without hypertonic saline did not increase b