ライフサイエンスコーパス: myometrium

1 try and excitability with development of the myometrium.

2 sensitization was not apparent in adult rat myometrium.

3 els of expression in brown fat, neurons, and myometrium.

4 ion factor binding when compared with normal myometrium.

5 evidence of disturbed differentiation of the myometrium.

6 primarily by defects in the formation of the myometrium.

7 pattern of each fibroleiomyoma and adjacent myometrium.

8 id was undetectable in either leiomyomata or myometrium.

9 ion proximal to the internal os and into the myometrium.

10 e to enhance the contractile response of the myometrium.

11 lieu that impacts both normal and neoplastic myometrium.

12 ernal os and extension of the tumor into the myometrium.

13 p to the internal os but did not involve the myometrium.

14 ooth muscle quiescence in the pregnant human myometrium.

15 endothelium as far as the first third of the myometrium.

16 and preceded substantial enhancement of the myometrium.

17 s no staining in the myocytes of nonpregnant myometrium.

18 expressed in smooth muscle cells of pregnant myometrium.

19 enta could be readily distinguished from the myometrium.

20 sel coverage was only 12% that of the normal myometrium.

21 of cells from rat circular and longitudinal myometrium.

22 essure of 4mmHg compared to -1mmHg in normal myometrium.

23 major component of GJs) and GJ formation in myometrium.

24 , no studies of the effect of lactate on the myometrium.

25 licited dose-dependent contractions on human myometrium.

26 hanism to explain the ability of NO to relax myometrium.

27 losed by the two smooth muscle layers of the myometrium.

28 modulating contractile activity in the human myometrium.

29 , which are linked with more mature SMCs and myometrium.

30 n non-pregnant to 54 +/- 7% in late pregnant myometrium.

31 aving the same properties as in non-pregnant myometrium.

32 n 5-HT-induced contractions in late pregnant myometrium.

33 reduced in both rat and mouse late pregnant myometrium.

34 rs of key biological functions in the normal myometrium.

35 re similar in non-pregnant and late pregnant myometrium (0.11 +/- 0.03 microM and 0.17 +/- 0.02 micro

36 In myometrium, 5-HT2 receptors not only play a role in cont

37 s in biomechanical properties of the scarred myometrium after CD.

38 r, and no fetal macrophages are found in the myometrium after labor.

39 monstrated a functional ARF6 system in human myometrium and a correlation between ARF6 level and acti

40 o significant stimulatory effect on both the myometrium and amnion.

41 the maxi-K channel are present in the mouse myometrium and are regulated differentially during gesta

42 gen and progesterone-dependent tumors of the myometrium and cause irregular uterine bleeding, severe

43 Serum progesterone profiles, myometrium and cervix function, and mitochondrial electr

44 soforms have been examined in human pregnant myometrium and cultured human myometrial smooth muscle c

45 kine expression in the placenta, and uterine myometrium and decidua, was also attenuated.

46 identifying the effects of ER ligands in the myometrium and elucidating their mechanism of action.

47 ZEB1 protein is up-regulated in the myometrium and endometrial stroma after progesterone or

48 shly derived strains of fibroblasts from the myometrium and endometrium also demonstrated heterogeneo

49 In situ staining of human myometrium and endometrium showed heterogeneous staining

50 We cloned Kv4.3 channel from myometrium and found that its protein and transcript exp

51 ACi exert anti-inflammatory effects in human myometrium and may thus be useful in achieving a myometr

52 eam contractile and inflammatory pathways in myometrium and neonatal pup brain.

53 Fibroblast subsets were used from human myometrium and orbit to test this hypothesis.

54 ractile or lipid-like phenotype in the human myometrium and orbit.

55 on cell signalling and contractility in rat myometrium and other smooth muscles.

56 ark contrast between fluorescence within the myometrium and relatively little within the fibroid tiss

57 man uterus, ZEB1 protein is increased in the myometrium and stroma during the secretory stage of the

58 * and LRP1 modulate the BKCachannel in human myometrium and that BKCaand its immunomodulatory interac

59 a to enhance the local metabolism of P(4) in myometrium and, thus, decrease PR function during the pr

60 tion of eosinophils, edema in the stroma and myometrium, and a decrease in the height of luminal epit

61 .5 revealed fibers within the vascular zone, myometrium, and endometrium, with greater density in the

62 e cells (SMC) of the vascular wall, bladder, myometrium, and gastrointestinal and respiratory tracts

63 and ability to evaluate the junctional zone, myometrium, and musculoskeletal structures for both sagi

64 We conclude that increased CGRP-Rs in myometrium, and resulting enhanced myometrial sensitivit

65 bserved ZEB1 promoter activity in the virgin myometrium, and stroma and myometrium of the pregnant ut

66 sis showed that CGRP-Rs are present in human myometrium, and that the expression of these receptors i

67 nscriptionally represses GPR10 in the normal myometrium, and that the loss of REST in fibroids permit

68 lays little role in SR Ca2+ release from the myometrium, and that there are gestational-dependent alt

69 EK-1 is more highly expressed than TREK-2 in myometrium, and there was no detectable expression of TR

70 Voltage-gated K+ currents in human myometrium are not well characterized, and were therefor

71 ppaB activation normally occurs in the mouse myometrium at gestation day E18, prior to labor, whereas

72 ession of nitric oxide synthase within human myometrium at midgestation, a time when the uterus is no

73 urrents at the resting membrane potential of myometrium at term.

74 Both need to be defined in pregnant human myometrium before the therapeutic potential of cAMP-elev

75 cant differences in stiffness of the scarred myometrium between the two phenotypes.

76 a mRNA levels were lower in leiomyomata than myometrium, but only during the luteal phase of the cycl

77 estrogen remodels the expression of Kv4.3 in myometrium by directly diminishing its transcription and

78 main population cells isolated from adjacent myometrium carried a mediator complex subunit 12 mutatio

79 a hormonal imprint on the developing uterine myometrium, causing an increase in expression of estroge

80 Accuracy levels in detecting invasion of the myometrium, cervical stroma, parametria and/or adnexae,

81 channels play a critical role in regulating myometrium contractility.

82 roximately 1% of all leiomyoma and 2% of all myometrium-derived cells.

83 ntly, mice overexpressing human GPR10 in the myometrium develop myometrial hyperplasia with excessive

84 Macrophage density in mice myometrium did not change with advancing gestational age

85 cantly decreased in pregnant mouse and human myometrium during labor.

86 CREM gene to be "switched" within the human myometrium during pregnancy from the production of CREMt

87 sion of several IGFBPs also occur within the myometrium during pregnancy.

88 ary, in the decidual vasculature, and in the myometrium during pregnancy.

89 splicing factor is tightly regulated in the myometrium during pregnancy.

90 Myometrium enhanced briskly (ME(90) of 110%), with a red

91 38 uterine leiomyomas and the corresponding myometrium from 30 women.

92 nexin-43 mRNA expression were reduced in the myometrium from 8-month-old vs. 3-month-old mice (P < 0.

93 tional profiling of leiomyoma and unaffected myometrium from humans and Eker rats, the best character

94 any effect on the inherent contractility in myometrium from late pregnant (19 days gestation) animal

95 sion and activity of 20alpha-HSD in laboring myometrium from mouse and human.

96 dent relaxation in spontaneously contracting myometrium from pregnant women.

97 as they progressed to labor and in laboring myometrium from pregnant women.

98 of proinflammatory cytokines from samples of myometrium from pregnant women.

99 -6 expression, barely detectable in the d7.0 myometrium, gradually increases until it is very strongl

100 changes in CGRP receptors (CGRP-Rs) in human myometrium have not been described.

101 Ovarian stroma enhanced less than myometrium in 30 of 43 cases.

102 o CGRP, may play a role in maintaining human myometrium in a quiescent state during pregnancy, and th

103 bal comparison of mRNA from leiomyoma versus myometrium in human and rat identified a highly signific

104 analyses of calcium dynamics in contracting myometrium in unprecedented spatiotemporal detail.

105 y have antiestrogenic effects in the uterine myometrium, in contrast to apparently estrogenic effects

106 induced contractility.Tonic stretch of human myometrium increases contractility and stimulates the ex

107 the expression of ARF6 and its GEF in human myometrium indicate a potential involvement of this sign

108 at autocrine prostaglandin signalling in the myometrium, initiated by elevated intrauterine cytokine

109 ) invasion of decidua and inner third of the myometrium is critical for a successful pregnancy.

110 ry, iNOS expression in the myocytes of human myometrium is increased greatly during pregnancy, and de

111 The uterine myometrium is the tissue of origin of an extremely commo

112 e, volumes, and differentiation into layers (myometrium, junctional zone, and endometrium) of uterine

113 Compared with normal human myometrium, leiomyomata had 3- to 5-fold higher levels o

114 pressed in malignant tumors derived from the myometrium (leiomyosarcomas), (b) is overexpressed in tu

115 ry epithelial cells, uterine endometrium and myometrium, mammary ductal epithelial cells, and the gas

116 ors containing histone acetylase activity in myometrium may contribute to the onset of labor by impai

117 In intact rat myometrium, MCD treatment increased Ca(2+) signalling an

118 that mediate the effect of stretch on human myometrium.Myometrial explants, prepared from biopsies o

119 Interestingly, myometrium not only clustered away from the tumors, but

120 levels (using immunoblotting) in samples of myometrium obtained from non-pregnant women, and women w

121 This relaxation effect is diminished in myometrium obtained from patients during labor and in th

122 and total protein are greatly diminished in myometrium of late pregnant rats versus nonpregnant anim

123 STAT5b expression coordinately decreased in myometrium of mice as they progressed to labor and in la

124 Expression of iNOS was highest in myometrium of preterm not-in-labor patients.

125 agonist effects, respectively, in the intact myometrium of sexually mature rats.

126 ity in the virgin myometrium, and stroma and myometrium of the pregnant uterus.

127 mbryogenesis, and is also upregulated in the myometrium of the uterus during pregnancy.

128 involved in PR gene activation in stroma and myometrium of the uterus in response to estrogen and pro

129 ndometrial glands and stroma deep within the myometrium of the uterus.

130 cs were assessed in comparison with those of myometrium on T1-weighted and gadolinium-enhanced images

131 ntified whose expression can distinguish the myometrium origin.

132 PrP-C than did intercaruncular endometrium, myometrium, oviduct, ovary, fetal bladder, or fetal kidn

133 ammatory cytokines IL-6 and IL-8 in cultured myometrium (P<0.05), compared to vehicle-treated control

134 etrial cells produces profound relaxation of myometrium precontracted by a broad spectrum of contract

135 Bitter tastants can completely relax myometrium precontracted by different uterotonics.

136 ant implications regarding activation of the myometrium prior to the onset of labor.

137 al and functional properties with native rat myometrium receptors, certain native P2Z purinoceptors a

138 nd biochemical studies provide evidence that myometrium remodelling during pregnancy is in part assoc

139 oM nickel to spontaneously contracting human myometrium reversibly slows contraction frequency.

140 identify proteins that interact with BKCain myometrium samples from term pregnant (>/=37 wk gestatio

141 presentative sections of fibroids and normal myometrium showed a smaller number of vessels with decre

142 sion of ERG1-3 (KCNH1-3) genes in the murine myometrium (smooth muscle layer of the uterus) and deter

143 presence of functional CRH receptors in the myometrium suggests that CRH may modulate myometrial con

144 (T1, 1,597 msec +/- 42; T2, 74 msec +/- 9), myometrium (T1, 1,514 msec +/- 156; T2, 79 msec +/- 10),

145 is study was to identify cell types in human myometrium that contain inducible nitric oxide synthase

146 alpha subunit splice variant (SV1) from rat myometrium that is also present in brain.

147 r fibroids, are benign tumors of the uterine myometrium that significantly affect up to 30% of reprod

148 In isometric tension studies of non-pregnant myometrium, the ERG channel blockers dofetilide (1 micro

149 ating differentiation and development of the myometrium, these data suggest that adenomyosis may be c

150 n extracts from uterine leiomyoma and normal myometrium tissues.

151 osure or dilation and even broke through the myometrium to develop extrusion outside the uterine horn

152 h gene expression data from term and preterm myometrium to identify subnetworks of PTB-SNP associated

153 s greater in the cervical lesion than in the myometrium was defined as time-signal intensity curve ty

154 acentas and spiral arteries from nonpregnant myometrium were cultured with angiogenic growth factors

155 This contrasts with rat myometrium, where there is a reduction of channel transc

156 re grossly deficient in smooth muscle of the myometrium, which has been replaced by adipose, a phenot

157 cular layer of the uterine wall known as the myometrium, which is composed mainly of smooth muscle ce

158 erstanding these mechanistic distinctions in myometrium will reveal molecular targets that are unique

159 rise from smooth muscle cells of the uterine myometrium with an incidence rate as high as 70% in wome

160 Incubation of myometrium with GRP receptor antagonists attenuates the

161 ignalling and contractility occurring in the myometrium with MCD.