ライフサイエンスコーパス: myopia

1 tical correction are accurate in identifying myopia.

2 tively correlated with older age and greater myopia.

3 the macular hole in MH-associated RD in high myopia.

4 oblems, especially among boys diagnosed with myopia.

5 to reduce the development and progression of myopia.

6 eractions contribute to the heterogeneity of myopia.

7 loss among almost 1 billion people with high myopia.

8 ntractures, mild skeletal dysplasia and high myopia.

9 atus, hypertension, diabetes, education, and myopia.

10 th an increase in the degree of preoperative myopia.

11 5 diopter (D), and 7 V4 model toric ICLs for myopia.

12 ual impairment specifically for persons with myopia.

13 e at which lacquer cracks form in pathologic myopia.

14 th recessively inherited nonsyndromic severe myopia.

15 ting its possible role in the development of myopia.

16 iously reported association between GJD2 and myopia.

17 and was recently negatively correlated with myopia.

18 rth orders in their relative protection from myopia.

19 tional collagen chemistry that could explain myopia.

20 llent improvement in vision for persons with myopia.

21 rs for their ability to predict the onset of myopia.

22 t OK lens wear was efficacious in correcting myopia.

23 reatening complications associated with high myopia.

24 but particularly sclera, causing progressive myopia.

25 f the iris and of the optic disc, and severe myopia.

26 ion between best-corrected visual acuity and myopia.

27 rse association between outdoor activity and myopia.

28 lity gene associated with the development of myopia.

29 is likely to contribute to the onset of high myopia.

30 ence of any degenerative lesion secondary to myopia.

31 isian ICL) implantation for moderate to high myopia.

32 ar features of the choroid in eyes with high myopia.

33 ic origin, positive family history, and high myopia.

34 commonly occurred in young individuals with myopia.

35 ia M2 microkeratome (MK) in mild to moderate myopia.

36 e retina-to-sclera signaling cascade causing myopia.

37 version of the Meta-Analysis for Pathologic Myopia.

38 39 loci associated with refractive error and myopia.

39 e important in diseases such as glaucoma and myopia.

40 certainty regarding increasing prevalence of myopia.

41 utorefraction was higher with hyperopia than myopia (0.73 [1.34] vs 0.05 [0.66], p = 0.01).

42 1.0 D), emmetropia (-0.99 D to 0.99 D), mild myopia (-1.0 D to -2.99 D), and moderate to high myopia

43 the more extreme eye was used to categorize myopia (-1.00 diopter [D] or more extreme) and hypermetr

44 s presented with excavated optic discs, high myopia (-1.00 to -16.00 diopters), and increased axial l

45 es underestimated hyperopia or overestimated myopia (-1.35 diopters [D] and -0.64 D, Spot and Plusopt

46 D 4.49]); rod dominated dystrophies (OR high myopia 10.1, P < .0001; OR high hyperopia 9.7, P = .001;

47 ercentage of noncitizens than US natives had myopia (18.8% vs 30.7%) or astigmatism (22.0% vs 30.9%).

48 lowed by cone-dominated dystrophies (OR high myopia 19.5, P < .0001; OR high hyperopia 10.7, P = .033

49 epithelium (RPE)-related dystrophies (OR low myopia 2.7; P = .001; OR high hyperopia 5.8; P = .025; S

50 .2%-31.5%]) and 163 million people with high myopia (2.7% of the world population; 95% CI, 86-387 mil

51 d congenital ptosis requiring surgery, 4 had myopia, 2 had retinal detachment, and 2 showed skeletal

52 We estimated 1406 million people with myopia (22.9% of the world population; 95% confidence in

53 associated with the highest risk of SE high myopia 239.7; odds ratio (OR) mild hyperopia 263.2, both

54 vision and refraction were amblyopia (32%), myopia (40%), and astigmatism (52%).

55 2050 there will be 4758 million people with myopia (49.8% of the world population; 3620-6056 million

56 The study group comprised 114 persons with myopia (81 girls and 33 boys), while the control group c

57 .4%-55.7%]) and 938 million people with high myopia (9.8% of the world population; 479-2104 million [

58 In high myopia, a region resembling the myopic peripapillary cre

59 In eyes with high myopia, after adjusting for age, choroidal vascular and

60 High myopia, age-related macular degeneration, or prostagland

61 A total of 1523 Chinese-American adults with myopia, aged 50 years and older, residing in the city of

62 ctor for glaucoma subtypes, low and moderate myopia also have a significant effect on glaucoma risk.

63 A significant increase in myopia among children and teenagers can be observed all

64 cataract, resulting in 371 participants with myopia and 2797 without.

65 espread and effective surgical treatment for myopia and astigmatic correction but whether it induces

66 ornea and sclera in chickens developing high myopia and astigmatism induced by form deprivation.

67 Myopia and astigmatism, two common refractive errors fre

68 raocular lenses (pIOLs) for the treatment of myopia and astigmatism.

69 situ keratomileusis (LASIK) in eyes with low myopia and compound myopic astigmatism </= 0.75 diopter

70 ial needs children who have moderate to high myopia and difficulties wearing glasses or contact lense

71 nalysis of the prevalence of myopia and high myopia and estimated temporal trends from 2000 to 2050 u

72 Myopia and high astigmatism (>2.5 diopter) were caused b

73 CASE PRESENTATION: Two patients with myopia and high corneal astigmatism underwent cataract o

74 ation), birth order was associated with both myopia and high myopia (eg, comparing first- vs second-b

75 eview and meta-analysis of the prevalence of myopia and high myopia and estimated temporal trends fro

76 studies show variations in the prevalence of myopia and high myopia between regions and ethnic groups

77 Odds ratios (ORs) for myopia and high myopia by birth order, using logistic re

78 Myopia and high myopia estimates from 2000 to 2050 sugge

79 artment (UNPD) to estimate the prevalence of myopia and high myopia in each country of the world.

80 from the United Kingdom and Israel suggested myopia and high myopia were approximately 10% more commo

81 Myopia and high myopia were defined as autorefraction of

82 R, 1.15; 95% CI, 1.06-1.25; P = 4.60E-04 for myopia and high myopia, respectively) and the apparent d

83 R, 1.21; 95% CI, 1.11-1.30; P = 3.60E-06 for myopia and high myopia, respectively).

84 gth difference (ALD) (minus and plus denotes myopia and hypermetropia, respectively).

85 cted cell type and causal gene; and risks of myopia and hyperopia were evaluated using logistic regre

86 3.10]) coincided with the highest degree of myopia and in CABP4 (SE 4.81 D [SD 0.35]) with the highe

87 ated optic disc anomaly associated with high myopia and increased axial length.

88 ether there is a genetic correlation between myopia and intelligence in over 1,500 subjects (aged 14-

89 bute significantly to the covariance between myopia and intelligence.

90 ing strategies to prevent the development of myopia and its complications could help to avoid an incr

91 th less than 12.00 diopters (D) of spherical myopia and less than 3.00 D of astigmatism were enrolled

92 ificantly thinner choroids in eyes with more myopia and longer AL at all locations except T2250 (P </

93 ects and among participants with more severe myopia and longer axial length (P < .001).

94 full astigmatic correction for eyes with low myopia and manifest cylinder of </= 0.50 D.

95 Mild myopia and moderate to high myopia groups were negativel

96 (PIOL) implantation has been used to correct myopia and myopic astigmatism, although corneal decompen

97 epidemiology and visual burden of pathologic myopia and myopic CNV.

98 ut underestimated hyperopia or overestimated myopia and overestimated astigmatism.

99 , we observed a stronger association between myopia and POAG among non-Hispanic whites (OR, 1.12; 95%

100 No independent associations between myopia and serum vitamin D3 concentrations nor variants

101 RNFL was thinner with increase in myopia and with decrease in disc area (p < 0.001).

102 chick eyes during the recovery from induced myopia, and apolipoprotein A-I mRNA was significantly in

103 banized area, having hypertension, diabetes, myopia, and being an former smoker (compared to a never

104 mall group of children (younger, with higher myopia, and greater tendency of myopic progression) who

105 of 13, 70%) of patients had moderate-to-high myopia, and none were using protective eyewear when they

106 or photophobia, reduced visual acuity, high myopia, and nystagmus.

107 , choroidal neovascularization (CNV) in high myopia, and other causes of CNV.

108 skeletal and eye abnormalities (ie, ptosis, myopia, and retina detachment).

109 Most of these individuals also have high myopia, and some have retinal dystrophy and patchy incre

110 tinopathy of prematurity (ROP) often develop myopia, and those who require laser treatment may develo

111 tinal pigment epithelium (RPE) humps in high myopia, and to describe the distinctive features from pa

112 ng manifestations: a prolapsed mitral valve, myopia, aortic root enlargement, and skeletal and skin m

113 Refractive errors, in particular myopia, are common in IRD.

114 linear models including age, gender, and 45 myopia-associated single nucleotide polymorphisms (SNP)

115 rmalities in childhood, including amblyopia, myopia, astigmatism, strabismus, limited ocular motility

116 pia to 33.7% (standard error, 0.08) for high myopia at 85 years of age.

117 eased age, 43% lower for every 1.0 D less in myopia at baseline, and 59% lower for every 1.0 D less i

118 alent refractive error at baseline, parental myopia, axial length, corneal power, crystalline lens po

119 The risk for myopia became progressively lower for later birth orders

120 al vascularity was greater in eyes with high myopia (beta = 0.032, P < .001).

121 iations in the prevalence of myopia and high myopia between regions and ethnic groups, and there cont

122 tions, there may be many subjects with axial myopia but shallow ACD and angle closure.

123 Odds ratios (ORs) for myopia and high myopia by birth order, using logistic regression and adj

124 In addition to measures of myopia by cycloplegic autorefraction and AL by A-scan ul

125 Future myopia can be predicted in a nonmyopic child using a sim

126 Myopia can cause severe visual impairment.

127 Increasing levels of myopia carry significant clinical and economic implicati

128 rment will occur if uncorrected, whilst high myopia causes sight-threatening complications.

129 These estimates were combined with myopia change estimates over time derived from regressio

130 tability of refraction in patients with high myopia compared with similar short-term studies.

131 reported the efficacy of orthokeratology for myopia control.

132 ere was no correlation between the degree of myopia correction and improvement in sensory and motor i

133 Myopia, currently at epidemic levels in East Asia, is a

134 en (mean age 21.59 +/- 1.15 years) with high myopia (defined as -6.0 diopter [D] or worse, mean spher

135 ese eye exercises and their association with myopia development in junior middle school children.

136 hotoreceptor may serve as critical sites for myopia development.

137 We also find in a mouse model of myopia downregulation of WNT7B expression in the cornea

138 ses, but an inverse dose-related increase in myopia during phase 2 (washout), resulting in atropine 0

139 der was associated with both myopia and high myopia (eg, comparing first- vs second-born individuals;

140 tients with infantile nystagmus syndrome and myopia equal to or more than -1 diopter (D), who were re

141 tamin D single-nucleotide polymorphisms, and myopia estimated from logistic regression.

142 Myopia and high myopia estimates from 2000 to 2050 suggest significant i

143 We suggest naming this entity high myopia-excavated optic disc anomaly.

144 went cataract surgery with a history of high myopia, eye trauma, or retinal detachment was 0.49%, 0.2

145 resents greater challenges than treatment of myopia for multiple reasons, including the fact that hyp

146 s an intervention for controlling children's myopia for over 50 years.

147 Education was significantly associated with myopia; for those completing primary, secondary, and hig

148 Because myopia frequently develops at a young age, Chinese Ameri

149 ater preoperative MRSE, greater preoperative myopia, greater preoperative astigmatism, and the occurr

150 Mild myopia and moderate to high myopia groups were negatively associated with developmen

151 Myopia >2.00 D was relatively uncommon (<2.0%) in all gr

152 Very high myopia (>/=-8.00 D) occurred in zone I in 2 of 52 (3.8%)

153 with those with emmetropia, those with high myopia had a significantly increased lifetime risk of vi

154 The prevalence of myopia has been reported as high as 90 % in some Asian c

155 Of all refractive errors, high myopia has the most severe visual consequences.

156 evels have increased and are associated with myopia, higher education seems to be an additive rather

157 Retinal detachment was associated with high myopia (HR, 6.12; 95% CI, 5.84-6.41), vitrectomy for per

158 Participants underwent LASIK surgery for myopia, hyperopia, and/or astigmatism.

159 magnitude of significant refractive errors (myopia, hyperopia, astigmatism, and anisometropia; P<0.0

160 Analyses compare myopia, hyperopia, astigmatism, and visual acuity betwee

161 ies of patients undergoing LASIK surgery for myopia, hyperopia, or astigmatism.

162 om -25 to +14 diopters; 796 persons had high myopia (ie, a spherical equivalent of -6 diopters or les

163 Importance: Myopia (ie, nearsightedness) is becoming the most common

164 been identified in a number of cases of high myopia, implicating it in the aetiology of this disorder

165 tients with infantile nystagmus syndrome and myopia improved monocular and binocular BCVA and contras

166 WNT7B significantly associates with extreme myopia in a case-control study with 1,478 Asian patients

167 16 years [range, 2-38 years]), all had high myopia in at least 1 eye and severely reduced vision.

168 o estimate the prevalence of myopia and high myopia in each country of the world.

169 set was defined as -0.75 diopters or more of myopia in each principal meridian in the right eye as me

170 With the increasing rate of myopia in many East Asian populations, there may be many

171 n be considered atypical forms of pathologic myopia in old age.

172 A sibling pair had unilateral high myopia in their right eyes and near emmetropia in their

173 Myopia is a common cause of vision loss, with uncorrecte

174 the inverse correlation due to the fact that myopia is a negative refractive error.

175 Although high myopia is a strong risk factor for glaucoma subtypes, lo

176 Pathologic myopia is an important cause of vision loss worldwide, a

177 Visual impairment due to myopia is an important public health issue.

178 Myopia is associated with higher intelligence.

179 Visual impairment due to myopia is associated with structural changes of the reti

180 ts that choroidal thinning in eyes with high myopia is associated with the reduction in both its stro

181 Myopia is becoming increasingly common globally and is a

182 Myopia is becoming more common in Europe; although educa

183 Along with its high prevalence, myopia is expensive to correct and is associated with oc

184 that the association between birth order and myopia is not due to a new environmental pressure in the

185 Myopia is the most common human eye disorder and it resu

186 Refractive errors, defined as myopia less than -3 diopters (D), hypermetropia greater

187 ia </=1.0 D; astigmatism, anisometropia, and myopia <1.0 D).

188 Refractive status was categorized as myopia (</=-0.50 diopter [D]), emmetropia (-0.50 to +0.5

189 (29.8%) were categorized as having moderate myopia (</=-2.0 to -5.0 D) and 11 (11.7%) were categoriz

190 ia (-1.0 D to -2.99 D), and moderate to high myopia (</=-3.0 D).

191 d 11 (11.7%) were categorized as having high myopia (</=-5.00 D).

192 Myopia may affect the level of trait anxiety among 13-14

193 Recent studies have suggested that myopia may be negatively correlated with the prevalence

194 As myopia may mitigate the impact of noncorrection, we perf

195 0/180 Snellen]), childhood-onset nyctalopia, myopia (mean [SD] refractive error, -6.71 [-4.22]), and

196 E more than -6.00 diopters (D), preoperative myopia more than 6.00 D, preoperative astigmatism more t

197 of "360.21: Progressive High (Degenerative) Myopia." Myopic CNV was defined as HM with the presence

198 Myopia (nearsightedness) has its onset in childhood and

199 Very high myopia occurred in zone II posterior in 1 of 58 (1.7%) e

200 each country, standardized to definitions of myopia of -0.50 diopter (D) or less and of high myopia o

201 pia of -0.50 diopter (D) or less and of high myopia of -5.00 D or less, projected to the year 2010, t

202 e: 24.3 +/- 1.4 years; 44.9% male) with mean myopia of -5.3 +/- 2.0 diopters and mean AL of 25.5 +/-

203 peropia of 0.73 D and slightly overestimated myopia of 0.05 D.

204 Cases were defined as 1. Myopia onset (cycloplegic spherical equivalent </= -0.5

205 luated, 10 were associated with the risk for myopia onset (P < .05).

206 ional cohort study of ocular development and myopia onset conducted at 5 clinical sites from Septembe

207 ror was consistently associated with risk of myopia onset in multivariate models (odds ratios from 0.

208 Myopia onset was defined as -0.75 diopters or more of my

209 iation between eye exercises and the risk of myopia-onset (OR = 0.73, 95%CI: 0.24-2.21), nor myopia p

210 7 eyes of 289 patients receiving the Artisan Myopia or Artisan Toric (Ophtec B.V., Groningen, The Net

211 ands) iris-fixated pIOL for the treatment of myopia or astigmatism at the University Eye Clinic Maast

212 efractive surgery option for those with high myopia or astigmatism.

213 ar Inner Retinal Defect Associated With High Myopia or Epiretinal Membrane," published online January

214 09 photoscreener in children with ametropia (myopia or hyperopia).

215 Both eyes of 21 patients received LASIK for myopia or myopic astigmatism.

216 trations was associated with a reduced OR of myopia (OR, 0.57; 95% CI, 0.46-0.72).

217 2.0; 95% CI, 1.5-2.6 per 10 mmHg; P<0.001), myopia (OR, 1.7; 95%, CI, 1.1-2.5; P<0.001), and axial l

218 le of years of education had twice the OR of myopia (OR, 2.08; 95% CI, 1.41-3.06).

219 Myopia, or near-sightedness, is our most common eye cond

220 e measures were the onset and progression of myopia over a two-year period.

221 atism (OR, 1.47; 95% CI, 1.00-2.16), but not myopia (P = 0.29).

222 with age-related macular degeneration (AMD), myopia, pachychoroid disease, and macular dystrophy, man

223 sed UVB exposure was associated with reduced myopia, particularly in adolescence and young adulthood.

224 The rapidly increasing prevalence of myopia poses a major public health challenge.

225 18 to 49 years of age with moderate to high myopia (preoperative corrected distance visual acuity [C

226 s a significant cohort effect for increasing myopia prevalence across more recent birth decades; age-

227 more recent birth decades; age-standardized myopia prevalence increased from 17.8% (95% confidence i

228 ation or being born in the 1960s doubled the myopia prevalence ratio-2.43 (CI, 1.26-4.17) and 2.62 (C

229 random-effects meta-analysis of age-specific myopia prevalence was performed, with sequential analyse

230 Children whose myopia progressed by more than 0.5 diopter (D) in the at

231 Children who had myopia progression (>/=-0.50 diopters [D] in at least 1

232 </= -0.5 diopter in non-myopic children). 2. Myopia progression (myopia shift of >/=1.0 diopter in th

233 pia-onset (OR = 0.73, 95%CI: 0.24-2.21), nor myopia progression (OR = 0.79, 95%CI: 0.41-1.53).

234 group persisted during phase 3, with overall myopia progression and change in axial elongation at the

235 In nonprogressors, the myopia progression at 1 year was less in the atropine-tr

236 opine 0.01% being most effective in reducing myopia progression at 3 years.

237 , overnight OK inhibits axial eye growth and myopia progression compared with conventional GP lenses.

238 ons on intraocular pressure measurements and myopia progression in school-aged children in Taiwan.

239 The lower myopia progression in the 0.01% group persisted during p

240 Therefore, controlling myopia progression is an urgent public issue.

241 high quality exercises had a slightly lower myopia progression of 0.15 D than the children who did n

242 ght orthokeratology was effective in slowing myopia progression over a twelve-year follow-up period a

243 .01% eyedrops were more effective in slowing myopia progression with less visual side effects compare

244 Axial length elongation and myopia progression with OK were compared with convention

245 ients with diabetes mellitus, glaucoma, high myopia, pseudoexfoliation, traumatic cataract, subluxate

246 Myopia ranged from -3.0 to -14.5 diopters (D), mean -9.2

247 visual impairment attributable to pathologic myopia ranged from 0.1%-0.5% (European studies) and from

248 ns thickness, and vitreous chamber depth-and myopia relate to the development of visual impairment ov

249 al interventions that may ultimately prevent myopia-related disease.

250 Myopia-related maculopathy is one of the leading causes

251 services, including managing and preventing myopia-related ocular complications and vision loss amon

252 tage genome-wide association study for three myopia-related traits in 9,804 Japanese individuals, whi

253 ma lutein concentrations and a lower risk of myopia requires replication.

254 1.06-1.25; P = 4.60E-04 for myopia and high myopia, respectively) and the apparent dose response was

255 1.11-1.30; P = 3.60E-06 for myopia and high myopia, respectively).

256 d disorder classically characterized by high myopia, retinal detachment, and occipital encephalocele,

257 g evidence for a direct role of vitamin D in myopia risk.

258 ont-optimized treatments are able to correct myopia safely and effectively in eyes with and without a

259 0 diopter [D]), mean of +2.50 D, and 21% had myopia (SE </=-0.50 D), mean of -1.40 D.

260 d pressure (SBP), faster heart rate, greater myopia, self-reported glaucoma, and colder season (all P

261 For myopia, sensitivity of the reason for optical correction

262 non-myopic children). 2. Myopia progression (myopia shift of >/=1.0 diopter in those who were myopic

263 Future trials for prevention of myopia should target the child with low hyperopia as the

264 lated with older age, female gender, greater myopia, smoking, body mass index (BMI), and white ethnic

265 2005) as well as case-control data from the Myopia Study (2010 to 2012) from the Netherlands.

266 he population-based studies, was 5.4% in the Myopia Study, and was 0.3% in controls.

267 Optix A09 refraction was 68.8 %, higher with myopia than hyperopia (90 % vs 54.5 %, p = 0.01).

268 l of trait anxiety in the group of boys with myopia than in the control group aged 13-17 years and 13

269 IVB was associated with less myopia than PRP, although longer follow-up was available

270 ommon cause of vision loss, with uncorrected myopia the leading cause of distance vision impairment g

271 In patients with moderate to high myopia, the AcrySof Cachet angle-supported pIOL provided

272 Myopia, the leading cause of visual impairment worldwide

273 ounger adolescents (13-14 years of age) with myopia there was a significantly higher incidence of pat

274 was associated with a reduced adjusted OR of myopia; those in the highest tertile of years of educati

275 dystrophy, a mild learning difficulty, high myopia, three limb post-axial polydactyly, horseshoe kid

276 ositive predictive values ranged from 7% for myopia to 56% for astigmatism.

277 Population-based studies reported pathologic myopia to be the first to third most frequent cause of b

278 Myopia was associated with an increased prevalence of al

279 Myopia was common in both sexes.

280 Myopia was defined as a mean spherical equivalent </=-0.

281 Myopia was defined as a mean spherical equivalent of -0.

282 High myopia was defined as myopic refractive error of </=6.0

283 Myopia was found among the most dominant 5.47% followed

284 More very high myopia was found in eyes that received laser treatment t

285 Overall, myopia was present in 94 subjects (22%), hyperopia was p

286 The prevalence of pathologic myopia was reported to be 0.9%-3.1%, and the prevalence

287 alence of CNV in individuals with pathologic myopia was reported to be 5.2%-11.3%, and was bilateral

288 Kingdom and Israel suggested myopia and high myopia were approximately 10% more common in first-born

289 Myopia and high myopia were defined as autorefraction of -0.75 diopters

290 equire laser treatment may develop very high myopia, which has considerable clinical consequences.

291 with lacquer cracks secondary to pathologic myopia who presented between 2010 and 2014 to 2 institut

292 h LCHADD, but not TFPD, showed an increasing myopia with a mean decrease in spherical equivalent refr

293 lation included 110 eyes of 55 patients with myopia with and without astigmatism.

294 nd laser-assisted in situ keratomileusis for myopia with consequent stabilization between 3 to 9 mont

295 spective study involving eight cases of high myopia with foveoschisis and foveal detachment in which

296 ria M2 MK are safe and effective in treating myopia with no statistically significant difference in i

297 ate racial differences in the association of myopia with the risk of POAG and NTG.

298 To examine the association of myopia with ultraviolet B radiation (UVB; directly assoc

299 weakness and bone dysplasia as well as high myopia, with evidence of clinical improvement of motor f

300 hierarchy of risk factors for RD onset: high myopia, young age, capsular rupture, history of eye trau