ライフサイエンスコーパス: myosin heavy chain

1 s (GRK2, atrial natriuretic factor, and beta-myosin heavy chain).

2 s such as atrial natriuretic factor and beta-myosin heavy chain.

3 protein HSP90, one (putative) HSP70, and the myosin heavy chain.

4 with actin and its C-terminal lobe with the myosin heavy chain.

5 factor, brain natriuretic peptide, and beta-myosin heavy chain.

6 and by performing immunostaining of neonatal myosin heavy chain.

7 enesis by stimulating the expression of slow myosin heavy chain.

8 smooth muscle alpha-actin and smooth muscle myosin heavy chain.

9 arboring heterozygous human mutations in the myosin heavy chain.

10 osine triphosphatase activity of the cardiac myosin heavy chain.

11 fferentiation markers myogenin and embryonic myosin heavy chain.

12 bers, which expressed an immature pattern of myosin heavy chains.

13 es), including those encoding four different myosin heavy chains.

14 n-2 slow and troponin T and carbonylation of myosin heavy chains.

15 Myosin heavy chain 1 (MYH1), myosin heavy chain 2 (MYH2)

16 Brg1 also supports Myosin heavy chain 11 (Myh11) expression to allow NCCs t

17 sease-causing mutations in at least 4 genes: myosin heavy chain 11 (MYH11), alpha-smooth muscle actin

18 s markers such as alpha smooth muscle actin, myosin heavy chain 11, and smooth muscle 22 alpha.

19 Myosin heavy chain 1 (MYH1), myosin heavy chain 2 (MYH2), and myosin heavy chain 7 (M

20 n and terminal differentiation (myogenin and myosin heavy chain 2) were increased on d 2 and 4 postin

21 ct CPAs expressed h-caldesmon and non-muscle myosin heavy chain-2; phenotypic markers of contractile

22 myosin heavy chain genes suggests that human myosin heavy chain 3 is the functional homologue of the

23 markers MyoD, myogenin and embryonic myosin (myosin heavy chain 3, MYH3).

24 (SOX2), GATA binding protein 4 (GATA4), and myosin heavy chain 6 (MYH6).

25 iquitination and UPS-mediated degradation of myosin heavy chain 6, cardiac myosin binding protein C,

26 ernal and maternal alleles of MYH6, encoding myosin heavy chain 6, in 2 patients who developed right

27 ntractile proteins (myosin light chain MLY2, myosin heavy chain 6, myosin-binding protein C), glucose

28 n 1 (MYH1), myosin heavy chain 2 (MYH2), and myosin heavy chain 7 (MYH7) were distributed broadly acr

29 by increased myoglobin, slow twitch markers [myosin heavy chain 7 (MyH7), succinate dehydrogenase, tr

30 s undergo antisense transcription, including myosin heavy chain 7 (Myh7), which encodes molecular mot

31 In parallel, mRNA expression of myosin heavy chain 7 and natriuretic peptide B is up-reg

32 Elevated myosin heavy chain 7 mRNA expression is detected in left

33 Thirteen variants in MYBPC3 and MYH7 (myosin heavy chain 7) were each identified >3 times and

34 ants, upheld(1) (up(1)), heldup(2) (hdp(2)), myosin heavy chain(7) (Mhc(7)), actin88F(KM88) (Act88F(K

35 pe 7; previously associated exclusively with myosin heavy chain 8 mutations).

36 ere we show the identification of non-muscle myosin heavy chain 9 (MYH9) as an essential factor for P

37 etected strong association between nonmuscle myosin heavy chain 9 gene (MYH9) variants on chromosome

38 suppresses TGF-beta-induced expression of SM myosin heavy chain, a late marker of SM differentiation.

39 diac myofilaments were identified on cardiac myosin heavy chain, actin, myosin light chains, and trop

40 Confocal imaging after immunostaining for myosin heavy chain, actinin, connexin-43, and von Willeb

41 use of a green fluorescent protein or a beta-myosin heavy chain adenovirus.

42 in the heart under the control of the alpha-myosin heavy chain (alpha-MHC) promoter.

43 rdiomyocytes in mice primarily express alpha-myosin heavy chain (alpha-MHC, also known as Myh6), wher

44 se heart, which contains predominantly alpha-myosin heavy chain (alpha-MyHC), the applicability of th

45 -MyHC) and reduced expression of adult alpha-myosin heavy chain (alpha-MyHC), with the net outcome of

46 Here, we show that the alpha-isoform of myosin heavy chain (alpha-MyHC, which is encoded by the

47 intracellular cardiac antigens, like cardiac myosin heavy chain-alpha, cardiac troponin-I, and adenin

48 d the gene expression profiles between alpha-myosin heavy chain (alphaMHC)-BMP10 transgenic hearts an

49 alpha-Myosin heavy chain (alphaMHC)-mTORkd mice had a near com

50 ated cardiac-specific MDA5 transgenic (alpha-myosin heavy chain [alphaMHC]-MDA5) mice.

51 ice, CD4+ T cells specific for cardiac alpha myosin heavy chain (alphaMYHC) cause myocarditis and mic

52 regulated by cardiac lineage promoters alpha-myosin heavy chain (alphaMyHC), Nkx2.5, or Mef2C.

53 rdiomyocytes that transiently express atrial myosin heavy chain (amhc) contributes substantially to s

54 single-copy transgene controlled by an alpha-myosin heavy chain (aMHC) promoter and coding for CFP.

55 As in the left ventricle, decrease in alpha-myosin heavy chain and a switch towards glycolysis from

56 Myosin heavy chain and actin were predominant proteins f

57 increased heart-to-body weight ratios, alpha myosin heavy chain and cardiac isoprostane levels, sugge

58 ressed the cardiac-specific antigens cardiac myosin heavy chain and cardiac troponin T, respectively

59 Patches of myosin heavy chain and dynamic furrowing of the plasma m

60 SMC phenotype with a marked reduction of SM-myosin heavy chain and increased proliferative capacity.

61 genes encoding the thick filament components myosin heavy chain and myosin binding protein C (MYH7 an

62 tic peptide, brain natriuretic peptide, beta-myosin heavy chain and myosin light chain (2- to 5-fold,

63 was seen in heart failure events between the myosin heavy chain and myosin-binding protein C genotype

64 h no differences in event rates seen between myosin heavy chain and myosin-binding protein C genotype

65 MYH7 and MYBPC3, encoding beta-myosin heavy chain and myosin-binding protein C, respect

66 tone marks and did not show up-regulation of myosin heavy chain and myotube formation when grown in d

67 bres, revealing the absolute fast isoform of myosin heavy chain and the abundance of glycogen and mit

68 structural proteins, such as alpha and beta myosin heavy chains and cardiac alpha actin, play crucia

69 ein that is homologous to the rod portion of myosin heavy chains and resides in thick filament cores.

70 actor, alpha-skeletal muscle actin, and beta-myosin heavy chain) and collagens were observed between

71 rtrophic cardiomyopathy (HCM) are MYH7 (beta-myosin heavy chain) and MYBPC3 (beta-myosin-binding prot

72 n natriuretic peptides, skeletal actin, beta-myosin heavy chain), and fibrosis (collagen III), and in

73 muscle alpha-actin (SM actin), smooth muscle myosin heavy chain, and calponin1, and the expression of

74 atrial natriuretic peptide, alpha- and beta-myosin heavy chain, and cardiac troponin T) by day 3 wit

75 the cardiac markers troponin I, troponin T, myosin heavy chain, and connexin-43.

76 A in polysomes, the levels of Mef2c and slow myosin heavy chain, and myofibril content.

77 in, myosin light chain kinase, smooth muscle myosin heavy chain, and SM22.

78 nnexin 43, myosin light chain 2a, alpha/beta-myosin heavy chain, and troponin I.

79 being peptides derived from nebulin, titin, myosin heavy chains, and troponin I proteins, those show

80 LP-1 haplodeficiency in the transgenic alpha-myosin heavy chain-angiotensinogen mice causes prominent

81 tions in the MYH7 gene encoding for the beta-myosin heavy chain are the underlying genetic cause of M

82 Two myosin heavy chains are expressed in the myoepithelial s

83 , we studied mice carrying the HCM mutation, myosin heavy-chain Arg403Gln, (MHC(403/+)) and an Mef2-d

84 e perform lineage tracing with smooth muscle myosin heavy chain as a marker and find that multipotent

85 In mice, these transcripts, which we named myosin heavy-chain-associated RNA transcripts (Myheart,

86 ick filaments throughout the cell cycle, (2) myosin heavy chain-based control of myosin assembly at t

87 erozygous missense mutations in beta-cardiac myosin heavy chain (beta-MHC).

88 results in enhanced expression of fetal beta-myosin heavy chain (beta-MyHC) and reduced expression of

89 the R403Q mutation in the gene encoding beta-myosin heavy chain (beta-MyHC).

90 GSK-3beta, enhanced calreticulin, Bax, p53, myosin heavy chain-beta isozyme switch, and IkappaB phos

91 The other is the endogenous beta-myosin heavy chain (bMHC) gene modified to code for a YF

92 red into a mouse genetic model of CHF (alpha-myosin heavy chain-calsequestrin), MCK-EcSOD transgenic

93 s disrupted when modeling human beta-cardiac myosin heavy chain cardiomyopathy mutations E497D or R71

94 later deletion of calcineurin with the alpha-myosin heavy chain Cre transgene resulted in lethality i

95 th heart defects, whereas deletion with beta-myosin heavy chain-cre (betaMHC-cre) produced viable adu

96 pecific LKB1 knock-out (KO) mice using alpha-myosin heavy chain-Cre deletor strain.

97 rdiac-specific ILK knockout mice using alpha-myosin heavy chain-driven Cre expression.

98 The expression and function of embryonic myosin heavy chain (eMYH) has not been investigated with

99 alpha-actin (encoded by ACTA2) and the beta-myosin heavy chain (encoded by MYH11).

100 gless (Wg) signaling pathway and a nonmuscle myosin heavy chain, encoded by the crinkled (ck) locus i

101 a muscle phenotype with rapid expression of myosin heavy chain, even in proliferative conditions.

102 re binding factor beta and the smooth-muscle myosin heavy chain), expressed in AML with the chromosom

103 ine of evidence for the differentiated alpha-myosin heavy chain-expressing cardiomyocyte as the cell

104 atal regenerating muscle, but only in type I myosin heavy chain-expressing cells.

105 ellular reactive oxygen species (ROS), alpha-myosin heavy chain expression (alpha-MHC), and intracell

106 Embryonic myosin heavy chain expression and central nucleation, in

107 ed CTX injury-induced myogenin and embryonic myosin heavy chain expression and increased the size of

108 sgenic mice further exhibited decreased beta myosin heavy chain expression compared to age matched no

109 Fiber type (myosin heavy chain expression) and 2DG accumulation were

110 entiation was confirmed by uniform NCAM1 and myosin heavy chain expression.

111 erexpression, on the other hand, enhances SM myosin heavy chain expression.

112 layed cardiac hypertrophy and increased beta myosin heavy chain expression.

113 myosin heavy chain primers revealed that the myosin heavy-chain expression in fused cells was derived

114 The expression of tail-specific myosin heavy chain (fmyhc2.1) requires wnt signaling and

115 of S100A4 in complex with a 45-residue-long myosin heavy chain fragment.

116 ded within an intron of alpha-cardiac muscle myosin heavy chain gene (Myh6), was actually a member of

117 Variation in the human beta-cardiac myosin heavy chain gene (MYH7) can lead to hypertrophic

118 oded within an intron of beta-cardiac muscle myosin heavy chain gene (Myh7).

119 In Drosophila melanogaster, a single myosin heavy chain gene encodes three alternative relay

120 sed by a premature stop codon in the cardiac myosin heavy chain gene myh6.

121 Alternative splicing of myosin heavy chain gene transcripts in Drosophila melano

122 study, we show that six fast muscle-specific myosin heavy chain genes have unique expression patterns

123 An expression profile of human skeletal myosin heavy chain genes suggests that human myosin heav

124 bridge kinetics bat and songbird SFM express myosin heavy chain genes that are evolutionarily and ont

125 of muscle-specific microRNAs embedded within myosin heavy chain genes, which control myosin expressio

126 myo2-E1) and deletion mutations of the other myosin heavy-chain genes.

127 ectrometry analysis revealed that non-muscle myosin heavy chain II A (NMHC IIA) is a protein targeted

128 antibody (m21G6) directed against nonmuscle myosin heavy chain II may inhibit IgM binding and reduce

129 A highly conserved self-antigen, nonmuscle myosin heavy chain II, has been identified as a target o

130 hypomorphic mice, showed that Myh10 encoding myosin heavy chain II-B is critical for cardiac and brai

131 cific alternative splicing of the non-muscle myosin heavy chain II-B pre-mRNA as a model.

132 Here, we show that nonmuscle myosin heavy chain IIA (MyH9) is recruited to LFA-1 at t

133 Subset 6 CLL mAbs recognize nonmuscle myosin heavy chain IIA (MYHIIA).

134 identified by mass spectrometry as nonmuscle myosin heavy chain IIA (MYHIIA).

135 heavy chain IIA, but does alter alignment of myosin heavy chain IIA and actin filaments creating the

136 with rat liver mitochondrial DNA: non-muscle myosin heavy chain IIA and beta-actin.

137 muscle fiber type specification by inducing myosin heavy chain IIA and suppressing myosin heavy chai

138 of the MYH9 gene that encodes the nonmuscle myosin heavy chain IIA are associated with diabetic neph

139 we conclude that the minimal binding site on myosin heavy chain IIA corresponds to A1907-G1938; there

140 ated with a missense mutation (E706K) in the myosin heavy chain IIa gene.

141 A4 and the C-terminal fragments of nonmuscle myosin heavy chain IIA has been studied by equilibrium a

142 sitive lipase, glutathione peroxidase-1, and myosin heavy chain IIa in quadriceps of control mice but

143 lysis suggest some beta-actin and non-muscle myosin heavy chain IIA reside within human mitochondria

144 gene silencing of MYH9 (encoding non-muscle myosin heavy chain IIA), or the closely related MYH10 ge

145 so identified a new Rab3 effector, nonmuscle myosin heavy chain IIA, as part of the complex formed by

146 Mts1 internalization or its interaction with myosin heavy chain IIA, but does alter alignment of myos

147 enriched at many muscle gene promoters (MCK, Myosin heavy chain IIa, Six4, Calcium channel receptor a

148 d that RUNX1-mediated silencing of nonmuscle myosin heavy chain IIB (MYH10) was required for megakary

149 Proteomic screening identified nonmuscle myosin heavy chain IIB (NMHCIIB), a subunit of nonmuscle

150 sely related MYH10 gene (encoding non-muscle myosin heavy chain IIB), altered the topology and increa

151 tion of the actin-bundling protein nonmuscle myosin heavy chain IIB, and junction remodeling.

152 in, fibrillarin, nuclear lamin B1, nonmuscle myosin heavy chain IIB, paxillin, Sec61 beta, tight junc

153 ucing myosin heavy chain IIA and suppressing myosin heavy chain IIB.

154 c signaling, the aberrant expression of beta-myosin heavy chain in adult Gsalpha-DF but not control m

155 and PCNA and decreased protein expression of myosin heavy chain in medial and neointimal VSMC.

156 s-sectional area and levels of the embryonic myosin heavy chain in regenerating muscle.

157 onal area and levels of embryonic isoform of myosin heavy chain in regenerating tibial anterior muscl

158 ated fibers, and the expression of embryonic myosin heavy chain in skeletal muscle of mdx mice.

159 The decrease in myosin heavy chain in the control sample was found after

160 nsgenic Drosophila lines expressing chimeric myosin heavy chains in indirect flight muscles lacking e

161 I have identified mRNAs associated with five myosin heavy chains in the fission yeast Schizosaccharom

162 ers (Skeletal alpha-actin, Desmin, and alpha-Myosin heavy chain) in skeletal and cardiac myocytes.

163 beta1 integrin, Pax7, myogenin and embryonic myosin heavy chain, indicating a restoration of the musc

164 arteries coexpressed smooth muscle actin and myosin heavy chain, indicating a smooth muscle cell iden

165 One of these RNAs, myosin heavy chain, is critical in presynaptic sensory n

166 ons in total muscle cross-sectional area and myosin heavy chain isoform (MyHC) composition.

167 Myosin heavy chain isoform composition of muscle samples

168 Myofiber size, myosin heavy chain isoform expression, and satellite cel

169 Cardiac myosin heavy chain isoform gene expression also showed a

170 erved decreased mRNA transcription levels of myosin heavy chain isoform IIa and a lower densitometric

171 shift towards a greater proportion of type I myosin heavy chain isoform in COPD.

172 er and relay domains vary between Drosophila myosin heavy chain isoforms due to alternative mRNA spli

173 We conclude that myosin heavy chain isoforms influence both SA kinetics a

174 reparation, the jump muscle, to determine if myosin heavy chain isoforms influence the magnitude and

175 layed in these mutant animals: expression of myosin heavy chain isoforms, the elimination of polyneur

176 ping, differentially regulated expression of myosin heavy chain isoforms.

177 1)R]), p47(phox) NADPH oxidase subunit, beta-myosin heavy chain isozyme switch, accumulation of AGE,

178 Myosin II assembly is regulated by myosin heavy chain kinase-mediated phosphorylation of it

179 Within this group, only eEF2K and myosin heavy chain kinases (MHCKs) have known substrates

180 Ectopically expressed myosin heavy chain kinases affinity purified from corA(-

181 normal in comparison with the alpha and beta myosin heavy chain knockdowns and controls.

182 ardiac myocytes and their inhibition blocked myosin heavy chain loss and myocyte atrophy, whereas inh

183 3, resulting in atrogin1/MAFbx upregulation, myosin heavy chain loss, and myotube atrophy.

184 We show alpha-myosin heavy chain MerCreMer and the MLC-2v promoters ar

185 IP), increased SRF activity, as well as beta-myosin heavy chain (MHC) and myocardin expressions.

186 a majority of sarcomeric proteins, including Myosin Heavy Chain (MHC) and Tropomyosin, require Hoip f

187 Troponin I (TnI) and myosin heavy chain (MHC) are two contractile regulatory

188 hy mutations in the filament-forming tail of myosin heavy chain (MHC) cause hypertrophic or dilated c

189 mutation at residue 403 (R403Q) in the beta-myosin heavy chain (MHC) caused a severe form of FHC was

190 HCM-causing Arg403Gln mutation in the alpha-myosin heavy chain (MHC) gene is inhibited by doxycyclin

191 rce production was reduced in OA patients in myosin heavy chain (MHC) I and IIA fibres (both P < 0.05

192 ts showed decreased cross-bridge kinetics in myosin heavy chain (MHC) I and IIA fibres, partially due

193 t was 64, 54, 160, and 138% more abundant in myosin heavy chain (MHC) I/IIa, MHC IIa, MHC IIa/IIx, an

194 myosin IIB and increased phosphorylation of myosin heavy chain (MHC) IIA on target sites known to re

195 n the cross sectional area and proportion of myosin heavy chain (MHC) IIB and low succinate dehydroge

196 on of Pax-7, MyoD, Myf5, Myf6, myogenin, and myosin heavy chain (MHC) in obestatin-infused rats when

197 hortening velocities, and/or a difference in myosin heavy chain (MHC) isoform content in chimpanzee r

198 d significantly elevated expression of alpha myosin heavy chain (MHC) isoform in epicardial fibres (1

199 erse ventricular remodeling characterized by myosin heavy chain (MHC) isoform switch and fibrosis, de

200 sarcomeres and was capable of deacetylating myosin heavy chain (MHC) isoforms.

201 d of sarcomeres and capable of deacetylating myosin heavy chain (MHC) isoforms.

202 To investigate myosin heavy chain (MHC) phosphorylation roles in 3D mig

203 We performed a proteomic analysis of myosin heavy chain (MHC) phosphorylation sites in MDA-MB

204 In gel samples made without salt (Lot A), no myosin heavy chain (MHC) polymerization was observed, on

205 eart using the cardiomyocyte- specific alpha-myosin heavy chain (MHC) promoter led to approximately a

206 Myosin heavy chain (MHC) was not carbonylated in chilled

207 The R403Q mutation in the beta-myosin heavy chain (MHC) was the first mutation to be li

208 pression of pyruvate dehydrogenase kinase 4 (myosin heavy chain (MHC)-PDK4 mice), an inhibitor of pyr

209 mutations in sarcomere proteins such as the myosin heavy chains (MHC) are the leading genetic causes

210 Fiber type (myosin heavy chain [MHC] isoform) and glucose uptake wer

211 isome proliferator-activated receptor-alpha (myosin heavy chain [MHC]-PPARalpha mice) exhibit phenoty

212 mice with higher expression levels of TRAF2 (myosin heavy chain [MHC]-TRAF2(HC)).

213 creased endogenous MyoD, Myogenin, and Myh3 (myosin heavy chain, [MHC] gene) mRNAs but not the cognat

214 lasia and ventricular septal defects in beta-myosin heavy chain-miR-195 transgenic mice.

215 nd up-regulated SM22, SM alpha-actin, and SM myosin heavy chain mRNA and protein levels.

216 own to be affected (in 2005) by a novel beta-myosin heavy-chain mutation that caused HCM, after an of

217 Nandrosol in Longissimus dorsi muscle, where myosin heavy chain (MYH) was significantly up-regulated.

218 cted protein-altering mutations in embryonic myosin heavy chain (MYH3) in three families.

219 , DCM) associated with mutations in the beta-myosin heavy chain (MYH7) gene product (Myosin-7).

220 , we have cloned the rat isoform of class II myosin heavy chain MyH7B in brain.

221 MIIA, NMIIB, and NMIIC, containing different myosin heavy chains (MYH9, MYH10, and MYH14, respectivel

222 by embryonic day 12.5 (E12.5), as assayed by myosin heavy chain (MyHC) and Myogenin staining.

223 d the candidate gene approach, targeting the myosin heavy chain (MyHC) gene.

224 fibers express five highly conserved type-II myosin heavy chain (MyHC) genes in distinct spatial and

225 The purpose of this study was to assess myosin heavy chain (MyHC) isoform expression and satelli

226 al area, myofiber size, satellite cells, and myosin heavy chain (MyHC) isoform expression was examine

227 histochemical analyses were used to quantify myosin heavy chain (MyHC) isoform expression, cross-sect

228 ning almost exclusively type IIb or IIx fast myosin heavy chain (MyHC) isoforms induced de novo synth

229 s that failed to express some characteristic myosin heavy chain (MyHC) proteins.

230 myofibril, before any measurable decrease in myosin heavy chain (MyHC).

231 The myosin heavy-chain (MyHC) gene family comprises multiple

232 The thick-filament component myosin heavy chain MYO-3 and the M-line component UNC-89

233 We also performed a detailed analysis of myosin heavy chain, myosin light chain, and myosin light

234 R2 and SERCA2, and the myofilament proteins, myosin heavy chain, myosin light chains and subunits of

235 ch donor indicated the actin-tropomyosin and myosin heavy chain-myosin light chain 1 interactions ind

236 of a disulfide-linked actin-tropomyosin and myosin heavy chain-myosin light chain 1.

237 (rs9583277) within the gene encoding for the myosin heavy-chain Myr 8 (MYO16), which has been implica

238 y studying mice and cells in which nonmuscle myosin heavy chain (NMHC) II-A is genetically replaced b

239 2 transgenic mouse models in which nonmuscle myosin heavy chain (NMHC) II-A was genetically replaced

240 splicing of a cassette exon N30 of nonmuscle myosin heavy chain (NMHC) II-B in the mouse central nerv

241 tissues stimulates phosphorylation of the NM myosin heavy chain on Ser1943 and causes NM myosin filam

242 ACh stimulated the phosphorylation of NM myosin heavy chain on Ser1943 in tracheal SM tissues, wh

243 tes and demonstrated downregulation of alpha-myosin heavy chain only in Gata4/Tbx5 heterozygotes.

244 pha-skeletal muscle actin (p<0.05), and beta-myosin heavy chain (p<0.05) were observed in AC6-KO mice

245 ed in BALB/c mice by immunization with alpha-myosin heavy chain peptide and complete Freund's adjuvan

246 the mechanoenzyme myosin II, independent of myosin heavy-chain phosphorylation, thus increasing cell

247 To address the effect of absence of NaCl on myosin heavy chain polymerization during two-step surimi

248 RT-PCR analysis using rat- or human-specific myosin heavy chain primers revealed that the myosin heav

249 pression of PPARgamma is driven by the alpha-myosin heavy chain promoter (alphaMHC-PPARgamma) were pr

250 In contrast, myosin heavy chain promoter (MHC)-ATGL mice were resista

251 tracycline-regulated, cardiac-specific alpha-myosin heavy chain promoter (V1A-TG).

252 tamoxifen-inducible Cre driven by the alpha-myosin heavy chain promoter are increasingly used to con

253 od1-null mice under the control of the alpha-myosin heavy chain promoter Tg(alphaMHC-Tmod1).

254 expression of iNOS in transgenic mice (alpha-myosin heavy chain promoter) did not induce contractile

255 promoter or the cardiomyocyte-specific alpha myosin heavy chain promoter, we identify a rare populati

256 ominant negative CELF protein under an alpha-myosin heavy chain promoter.

257 ardiomyocytes under the control of the alpha-myosin heavy chain promoter.

258 constitutively active (ca) mTOR, using alpha-myosin heavy chain promoter.

259 h driven by the cardiomyocyte-specific alpha-myosin heavy chain promoter.

260 inase under the control of the smooth muscle myosin heavy-chain promoter resulted in cardiopulmonary

261 conditional ROCK2(flox/flox) mice and alpha-myosin heavy-chain promoter-driven Cre recombinase trans

262 r gamma 1 (PPARgamma1) via the cardiac alpha-myosin heavy-chain promoter.

263 crossed into merCremer mice under the alpha-myosin heavy-chain promoter.

264 a lower densitometric ratio of fast-to-slow myosin heavy chain protein content.

265 Overexpression of the beta-myosin heavy chain protein contributes to the pathologic

266 OligoCS maintains almost all myosin heavy chain protein degradation as observed in th

267 rophy attributable to a specific decrease in myosin heavy chain protein.

268 f2ca translation and level of Mef2c and slow myosin heavy chain proteins caused by inactivity.

269 METHODS AND We treated 2-year-old beta-myosin heavy-chain Q403 transgenic rabbits with establis

270 modeling, including decreased alpha- to beta-myosin heavy chain ratios, and induced maladaptive chang

271 tive versions of the Drosophila melanogaster myosin heavy chain relay domain on muscle mechanical pro

272 These mice were crossed with alpha-myosin heavy chain reverse transcriptional transactivato

273 [GSK3beta], a 20-fold up-regulation of beta myosin heavy chain RNA and elevated G(s)alpha/G(i)alpha

274 ons in the beta-cardiac/slow skeletal muscle myosin heavy chain rod.

275 ated NM myosin RLC phosphorylation and by NM myosin heavy chain Ser1943 phosphorylation.

276 TDG in SMCs increased smooth muscle-specific myosin heavy chain (SM MHC) and Telokin gene expression.

277 ection is MYH11, which encodes smooth muscle myosin heavy chain (SM-MHC).

278 ion of Runx2 modulates Cbfbeta-smooth muscle myosin heavy chain (SMMHC)-mediated myeloid leukemia dev

279 he interaction between CBFbeta-smooth muscle myosin heavy chain (SMMHC; encoded by CBFB-MYH11) and RU

280 Birth weight correlated positively with CSE, myosin heavy chain, smooth muscle actin, and desmin, and

281 eversed end-diastolic flow contained reduced myosin heavy chain, smooth muscle actin, and desmin, and

282 CSE correlated positively with myosin heavy chain, smooth muscle actin, and desmin.

283 ecific (Tie2, Cdh5, Pdgfb) and smooth muscle myosin heavy chain-specific Cre driver mouse lines to pr

284 th decreased alpha myosin and increased beta myosin heavy chains, suggesting an alpha-to-beta convers

285 B, suggest that the C-terminal region of the myosin heavy chain supersedes the distinct motor propert

286 eration marked by dysregulation of embryonic myosin heavy chain temporal expression.

287 ivided into four categories according to the myosin heavy chain that they express: I, IIA, IIX and II

288 to the light meromyosin (LMM) region of the myosin heavy chain, the underlying molecular mechanism c

289 r than heat-induced breakdown of part of the myosin heavy chains, the 2-DE pattern of cooked ham was

290 ming the disorder from a disease of the beta-myosin heavy chain to a disease of the cardiac sarcomere

291 levels of differentiation markers (myogenin, myosin heavy chain, troponinT-1, and Pax3) and impaired

292 C)-specific isoforms of alpha-actin and beta-myosin heavy chain, two major components of the SMC cont

293 m 0.2 to 0.6) in the gene encoding nonmuscle myosin heavy chain type II isoform A (MYH9) were associa

294 Binding to the myosin heavy chain was associated with a large conformat

295 This selective degradation of myosin heavy chain was not accompanied by a decrease in

296 on rate, surface area, or expression of beta-myosin heavy chains was significantly greater in AKAP5(-

297 er genes, atrial natriuretic factor and beta-myosin heavy chain, were not up-regulated in E33A-treate

298 des could lower the denaturation of crayfish myosin heavy chain when compared to the control.

299 including SM alpha-actin, SM22alpha, and SM myosin heavy chain, whereas Olfm2 overexpression promote

300 latory light chain (RLC) binding site in the myosin heavy chain with concomitant dissociation of the