ライフサイエンスコーパス: myotomal

1 sh embryos, stac3 was initially expressed in myotomal adaxial cells and in fast muscle fibers post-se

2 We find that myotomal and primary myogenesis proceed normally in homo

3 wn to pattern the somite into dermomyotomal, myotomal and sclerotomal cell fates.

4 patterned expression of myoD and pax1 in the myotomal and sclerotomal lineages following somite forma

5 transducing the Sonic hedgehog signal to the myotomal and sclerotomal lineages.

6 l and ventral somite cells that give rise to myotomal and sclerotomal lineages.

7 1 to Shh(-/-);Gli3(-/-) embryos restores the myotomal basement membrane, demonstrating that laminin-1

8 y and sufficient to initiate assembly of the myotomal basement membrane.

9 this defect is due to the failure to form a myotomal basement membrane.

10 marks the epaxial-hypaxial dermomyotomal or myotomal boundary.

11 expression of MyoD and Myf5 to give rise to myotomal cells in the medial somite.

12 es demonstrate that a distinct population of myotomal cells plays a pivotal role in the early migrati

13 gene activity is required in a small set of myotomal cells, called adaxial cells.

14 nd E12.5 and in skeletal muscle cells in the myotomal compartment of the somites between E9.5 and E12

15 lacZ reporter gene to arterial SMCs and the myotomal component of the somites.

16 scle pattern and mass, suggesting that early myotomal defects are corrected by a Dmrt2-independent me

17 pends upon the underlying somitic cells, the myotomal derivatives of which--both slow--and fast-twitc

18 induced by the forelimb field which promotes myotomal extension directly from the somites.

19 Myf5/Myod1 mutants results from loss of the myotomal FGF proteins, which depend upon Myf5 and Myod1

20 nitially restricted to the centrally located myotomal fiber nuclei.

21 individual fiber size, but had no effect on myotomal fiber phenotype.

22 transcripts spread throughout the length of myotomal fibers in order of their appearance.

23 always distributed throughout the length of myotomal fibers, the mRNA for each slow myosin heavy cha

24 fast myosin heavy chain is not expressed in myotomal fibers.

25 w myosin heavy chain mRNA transcripts within myotomal fibers.

26 nally, we provide evidence that hypaxial and myotomal gene expression is mispatterned in Gli2-/-Gli3-

27 trunk cells that will develop into aberrant myotomal-like structures.

28 rentiation, and higher levels induce loss of myotomal markers and activation of sclerotomal gene expr

29 maintain the expression of dermomyotomal and myotomal markers.

30 s of permeabilized white fibres from dogfish myotomal muscle at their physiological temperature, 12 d

31 compelling evidence that during pathfinding, myotomal muscle cells communicate extensively with exten

32 nic gene expression and the determination of myotomal muscle in somites are discussed.

33 isms underlying synapse formation within the myotomal muscle itself are largely independent of those

34 transcripts of myoD1 in developing and adult myotomal muscle of T. rubripes supports the hypothesis t

35 assigned to tropomyosin alpha-1 chain, fast myotomal muscle troponin T and parvalbumin beta 2 increa

36 ure but were capable of differentiating into myotomal muscle within the somites.

37 he somatopleure without differentiating into myotomal muscle, but differentiated into muscle fibers w

38 he most abundant transcript in fast and slow myotomal muscle.

39 axons form en passant synaptic contacts with myotomal muscle.

40 tional communication between motor axons and myotomal muscle.

41 Innervated regions of myotomal muscles were compared in animals injected with

42 ts for Myf-5-dependent activation of MyoD in myotomal muscles.

43 both MRF4 alleles and increased deficits in myotomal Myf-5 expression.

44 ncy in cis regulatory mechanisms controlling myotomal MyoD expression.

45 evealed enrichment of SRF transcripts in the myotomal portion of somites, the myocardium of the heart

46 e myocardium of the developing heart and the myotomal portion of somites.

47 To assay changes in the specification of myotomal precursor cells during somite maturation, we im

48 n; a key morphogenetic cell movement whereby myotomal precursor cells leave the dermomyotome epitheli

49 tome and move into the myotome, and later in myotomal precursors destined to migrate towards their fi

50 ion in the segmented axial muscles and their myotomal precursors, fortuitously marking their position

51 ntenance of expression of QmyoD and Qmyf5 in myotomal progenitor cells during the period immediately

52 ary motor axons innervated their appropriate myotomal territories, indicating that N-cadherin regulat

53 of quail embryos and their capacity to form myotomal tissue assessed by confocal microscopy.

54 the expression patterns of dermomyotomal and myotomal transcription factors including Pax3, Paraxis,

55 Myotome precursor cells undergo myotomal translocation; a key morphogenetic cell movemen

56 ing evidence that diwanka (lh3) acts through myotomal type XVIII collagen, a ligand for neural-recept