ライフサイエンスコーパス: myxoid

1 es of CS (8 extraskeletal myxoid, 4 skeletal myxoid, 4 mesenchymal, and 30 other) for the EWS/CHN gen

2 We studied 46 cases of CS (8 extraskeletal myxoid, 4 skeletal myxoid, 4 mesenchymal, and 30 other)

3 iated, 143 (18%) dedifferentiated, 144 (18%) myxoid, 81 (10%) round cell, and 64 (8%) pleomorphic his

4 pendent prognostic factor in the spectrum of myxoid and round-cell liposarcomas has not been examined

5 Forty-seven cases of myxoid and round-cell liposarcomas were examined.

6 expression predicts the clinical behavior of myxoid and round-cell liposarcomas, even in neoplasms wi

7 65 (37%) with dedifferentiated, 9 (5%) with myxoid, and 4 (2%) with round cell morphology.

8 Areas of myxoid change showed similar but less pronounced alterat

9 Extensive areas of myxoid change were found in all aortic valves.

10 The pathogenesis of myxoid chondrosarcoma (CS) is poorly understood.

11 studies have established that extraskeletal myxoid chondrosarcoma is a unique entity defined by the

12 locations (eg, cemento-ossifying fibroma and myxoid chondrosarcoma) and the association of establishe

13 uperfamily located at 9q22-31, in a skeletal myxoid chondrosarcoma.

14 A proportion of extraskeletal myxoid chondrosarcomas (EMC) have been shown to have a c

15 r genetic findings, except for extraskeletal myxoid chondrosarcomas.

16 etic changes are diagnostic of extraskeletal myxoid chondrosarcomas.

17 (32%) had unusual histologies (pleomorphic, myxoid, clear cell, and signet ring cell).

18 gs in the latter cases suggest that skeletal myxoid CS is pathogenetically distinct from its extraske

19 Notably, 2 cases of extraskeletal myxoid CS showed neither an EWS/CHN fusion transcript no

20 Extraskeletal myxoid CS thus represents yet another sarcoma type conta

21 g genetic heterogeneity within extraskeletal myxoid CS.

22 ognized in CS, specifically in extraskeletal myxoid CS.

23 ed in only a limited number of extraskeletal myxoid CSs and its presence in other types of CS has not

24 e fusion was present in 6 of 8 extraskeletal myxoid CSs and was not detected in any of the remaining

25 he remaining cases, including the 4 skeletal myxoid CSs.

26 nitially formed small tumors later underwent myxoid degeneration and completely regressed.

27 ough numerous articles on MVP (myxomatous or myxoid degeneration, billowing or floppy mitral valve) h

28 is a characteristic constituent of the loose myxoid ECM in human restenotic arteries and of the neoin

29 The loose myxoid ECM typical of human restenotic arteries demonstr

30 imaging appearances that probably represent myxoid fibroadenomas or ductal adenomas.

31 s in six patients and complex cystic masses (myxoid fibroadenomas) in one patient.

32 Myxoid liposarcoma is characterized by a pathognomonic c

33 s of formalin-fixed, paraffin-embedded human myxoid liposarcoma tissues, we demonstrate an 80% reduct

34 ors, and one each of infantile fibrosarcoma, myxoid liposarcoma, cellular congenital mesoblastic neph

35 a level comparable to that observed in human myxoid liposarcoma.

36 pressed in the neoplastic component of human myxoid liposarcomas and increases the tumorigenicity of

37 Synovial sarcomas, round-cell/myxoid liposarcomas, clear-cell sarcomas and gastrointes

38 oncoprotein, found in the majority of human myxoid liposarcomas, consists of a fusion between the tr

39 ar, a subset of Ewing's family of tumors and myxoid liposarcomas, which lack one of the characteristi

40 ogical function and protein structure of the myxoid matrix in optic gliomas to identify novel therape

41 The myxoid matrix is composed predominantly of the proteogly

42 ted adipocytes, primitive mesenchymal cells, myxoid matrix, and fibrous trabeculae.

43 erent stages of maturation within a variably myxoid matrix, and they contain clonal rearrangements of

44 oma, a subtype of optic glioma with abundant myxoid matrix, is characterized by the presence of endot

45 Optic gliomas contain various amounts of myxoid matrix, which can represent most of the tumor mas

46 luronan and proteoglycan link protein 1 rich myxoid matrix, which is in direct contact with circulati

47 presence of endothelium-free channels in the myxoid matrix.

48 clusion and multinucleated cells in a partly myxoid matrix.

49 optic gliomas, which varied in the amount of myxoid matrix.

50 mbled the loose-connective-tissue-containing myxoid region typical of restenotic lesions.

51 Myxoid round cell liposarcoma (MRCLS) is a common liposa

52 DSS were smaller size (HR = 0.7, P = 0.01), myxoid/round cell histologic subtype (HR = 0.3, P = 0.03

53 nd induces apoptosis in dedifferentiated and myxoid/round cell liposarcoma cell lines, but not in eit

54 a) well-differentiated/dedifferentiated, (b) myxoid/round cell, and (c) pleomorphic, based on morphol

55 ith advanced or metastatic dedifferentiated, myxoid/round cell, or pleomorphic LPS incurable by surge

56 pleomorphic liposarcomas) and PIK3CA (18% of myxoid/round-cell liposarcomas, or MRCs).

57 agen and elastic fibers) with focal areas of myxoid stroma, with or without coverage by endothelial c

58 Myxoid tissue containing extracellular matrix (ECM) enri

59 The stroma seemed to be myxoid to collagenous.

60 ;22)(q22-31;q11-12) has been observed in the myxoid variant of human chondrosarcoma.

61 ate-like channels, which we termed primitive myxoid vascularization.