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3 , vaccinia virus (VACV), but also cowpox and myxoma viruses, are able to evade host IFN responses.
4 t that infection of primary murine pDCs with myxoma virus, but not with vaccinia virus, induces IFN-a
6 from genetic knockout mice, we show that the myxoma virus-induced innate immune response requires the
7 rmacological inhibitors, we demonstrate that myxoma virus-induced type I IFN and IL-12p70 production
9 Serp2 protein encoded by the leporipoxvirus myxoma virus is essential for full virulence and, like c
11 to those coding for interleukin-1 receptor, myxoma virus M003.2 and M004.1 genes (two copies each),
12 romelia virus macrophage host range protein, myxoma virus M011L, variola virus B22R, four ankyrin rep
13 that vaccinia virus p28 and its homologue in myxoma virus, M143R, can mediate the formation of polyub
15 determined the crystal structures of C7 and myxoma virus M64, a C7 family member that is unable to a
20 be determined.IMPORTANCE The species jump of myxoma virus (MYXV) from the South American tapeti to th
27 ft model, we serendipitously discovered that myxoma virus (MYXV) prevented GVHD while permitting GVM.
31 in the orthologous M029 protein expressed by myxoma virus, plays an inhibitory role in poxvirus sensi
33 ntagonized in a dose-dependent manner by the myxoma virus rabbit IFN-gamma receptor homolog, M-T7.
34 some poxvirus serpins regulate inflammation (myxoma virus SERP1 and cowpox virus [CPV] crmA/SPI-2) or
35 cowpox virus [CPV] crmA/SPI-2) or apoptosis (myxoma virus SERP2 and CPV crmA/SPI-2), the function of
36 inhibition, we generated a novel recombinant myxoma virus (vPD1), which inhibits the PD1/PDL1 pathway
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