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1 r androgen deprivation therapy (ADT) (86.0%, n = 308) alone or combined with radiotherapy in prostate
6 wed an IC50 value of 37.1 +/- 2.4 ng mL(-1) (n = 9), a detection limit of 11.1 ng mL(-1), and a dynam
7 this effect in four field studies (study 1: n = 870; study 2: n = 246; study 3: n = 870; study 4: n
8 empirically conducted with 50 (n = 4), 100 (n = 4), 150 (n = 2), and 200 kBq/kg (n = 4) of (225)Ac-P
9 study participants included 38 nurses, 100% (n = 38) of whom were white and 92% (n = 35) of whom were
12 conducted with 50 (n = 4), 100 (n = 4), 150 (n = 2), and 200 kBq/kg (n = 4) of (225)Ac-PSMA-617 were
16 = 13) of "CF negative" (n = 152) and 19.4% (n = 13) of "CF negative" LT + STp (n = 67) expressing is
17 3,461 patients were included, and only 5.4% (n = 731) bypassed a rural hospital for their emergency d
20 age therapies empirically conducted with 50 (n = 4), 100 (n = 4), 150 (n = 2), and 200 kBq/kg (n = 4)
23 reening of ETEC isolates revealed that 8.6% (n = 13) of "CF negative" (n = 152) and 19.4% (n = 13) of
25 with a negative PSMA who received SRT, 85% (n = 23/27) demonstrated a treatment response, compared w
26 s, 100% (n = 38) of whom were white and 92% (n = 35) of whom were female, and 100 children, 51% (n =
28 omic assay to analyze moderate-to-severe AD (n = 59) compared to psoriasis (n = 22) and healthy contr
31 r consumption of raw carrots.Healthy adults (n = 12) consumed a meal containing 300 g raw carrot (pro
33 ut amyloid-beta accumulation (normal ageing, n = 13), and neurologically normal elderly with cortical
35 ntrol study, we assessed the outcome of all (n = 95) renal transplanted patients with pretransplant c
36 ced usual care (EUC) (n = 247) or EUC alone (n = 248), of whom 95% completed assessments at 3 months,
37 d the inclusion criteria, all cases with AN (n = 216) and 300 randomly selected individuals without A
40 cated individuals with pathological anxiety (n = 25) and matched healthy control subjects (n = 23) co
43 or Interventional Trials) guideline authors (n = 16), pharmaceutical industry statisticians (n = 3),
44 rious herbal products (n = 3), azithromycin (n = 2), and 15 other medications or dietary supplements.
45 ng with MDD before the study or at baseline (n = 27), offspring with an episode of MDD that had remit
47 ar period that had undergone liver biopsies (n = 363) were scored for the presence of bile duct loss
49 tion in a representative sample of US Black (n = 4,201), non-Hispanic White (n = 20,217) and Hispanic
50 hings were collected from patients with BOS (n = 10), stable lung transplant patients (n = 18), and h
52 signed to docetaxel (n = 41) or cabazitaxel (n = 22); 44.4% received prior potent androgen receptor-t
53 the same period, deaths after breast cancer (n = 134) were significantly reduced (40 deaths [0.025% p
54 se-control study using hospital-based cases (n = 127) and control subjects representative of the hosp
55 rtical areas from Alzheimer's disease cases (n = 19), neurologically normal elderly without amyloid-b
58 ndependent population of asthmatic children (n = 30) by using a shared healthy control population (n
60 (n = 35), imipenem (n = 1) or ciprofloxacin (n = 1) in addition to known resistance determinants, col
61 ted agents included amoxicillin/clavulanate (n = 3), temozolomide (n = 3), various herbal products (n
63 tial for growth during exposure to colistin (n = 35), imipenem (n = 1) or ciprofloxacin (n = 1) in ad
64 Coma Recovery Scale-Revised indicated coma (n = 2), vegetative state (n = 3), minimally conscious st
65 well vascularized (n = 32) and compromised (n = 27) parathyroid glands during thyroid surgery with a
67 these incidents had respiratory conditions (n = 387; 18%), injuries (n = 289; 13%), nonspecific sign
69 (n = 41) and healthy non-allergic controls (n = 42) performed a dual-task paradigm and a verbal lear
71 9) falciparum malaria, and healthy controls (n = 50), we measured parasite biomass, systemic inflamma
74 ium pyrophosphate deposition disease (CPPD) (n = 15), from the Hamann-Todd collection of human skelet
75 urinary FSH values (>11.5 mIU/mg creatinine [n = 69]) did not have a significantly different predicte
76 We collected NLFs from patients with CRSsNP (n = 33), CRSwNP (n = 45), and AERD (n = 31) and control
77 from patients with CRSsNP (n = 33), CRSwNP (n = 45), and AERD (n = 31) and control (n = 24) subjects
84 ected and assayed before (n = 327), 14 days (n = 82), 49 days (n = 112) and 84 days (n = 115) after i
85 before (n = 327), 14 days (n = 82), 49 days (n = 112) and 84 days (n = 115) after iron supplementatio
86 ays (n = 82), 49 days (n = 112) and 84 days (n = 115) after iron supplementation (60 mg iron as ferro
91 were likely to experience stage IVE disease (n = 35 of 55; 64%), with bilateral involvement (n = 27 o
92 se with high-normal aldosterone (>/=9 ng/dL, n = 202), we found no significant association between se
93 = 29), diffuse large B-cell lymphoma (DLBCL; n = 34), DLBCL arising from chronic lymphocytic leukemia
94 atients were randomly assigned to docetaxel (n = 41) or cabazitaxel (n = 22); 44.4% received prior po
95 med a denser network (total number of edges, n = 173) than the distal colorectal cancer network (n =
96 stry statisticians (n = 3), journal editors (n = 9), and regulators (n = 2) (3 participants were incl
98 ral, and domesticated) and treated effluent (n = 233) was used to generate a fecal library to perform
101 uded hyphema (n = 3; 6.8%), endophthalmitis (n = 1; 2.3%), wound leak (n = 1; 2.3%), and choroidal de
102 o either HAP plus enhanced usual care (EUC) (n = 247) or EUC alone (n = 248), of whom 95% completed a
104 we investigate an existing data set on eye (n = 625) and skin (n = 684) color from Cape Verde, an is
107 nonspecific signs and symptoms, e.g., fever (n = 281; 13%), and gastrointestinal or genitourinary con
108 homa (MCL; n = 28), follicular lymphoma (FL; n = 29), diffuse large B-cell lymphoma (DLBCL; n = 34),
109 cing in prediagnostic mouthwash samples from n = 81/160 EAC and n = 25/50 ESCC cases/matched controls
111 riptomic variation; a small number of genes (n = 263) were differentially regulated according to the
112 elegans mutations in dopamine-related genes (n = 45) for changes in tau transgene-induced behavioral
113 tics of Asthma and Lifestyle Study (PR-GOAL; n = 306) and the Genes-environments and Admixture in Lat
114 tion group (n = 174) or standard care group (n = 197); 89.2% of participants completed the study.
117 ow-up, patients from the intervention group (n = 168) showed a significantly better improvement compa
118 onths) randomized to the intervention group (n = 174) or standard care group (n = 197); 89.2% of part
120 (P = .001) in the canakinumab-treated group (n = 5 of 7) than in the placebo group (n = 0 of 13).
121 improvement compared with the waiting group (n = 147) in the following defined primary study outcomes
122 erior teeth; n = 12 for each anterior group, n = 13 for each posterior group) for 2 tissue types (ena
127 ssigned to a 6-month interventionist-guided (n = 125) or self-guided (n = 121) weight loss program su
128 rventionist-guided (n = 125) or self-guided (n = 121) weight loss program supporting behavioral chang
129 istory of graft-versus-host disease (GVHD) ( n = 27) was associated with higher proportions of Firmic
130 G1) consisted of patients with HIV on HAART (n = 176), Group 2 (G2) consisted of patients with HIV wh
131 of patients with HIV who were not on HAART (n = 48), and Group 3 (G3) consisted of controls without
133 cytokine profiles of 411 patients with HCC (n = 102: 32% HBV, 54% HCV, 14% non-viral) and without HC
142 ing exposure to colistin (n = 35), imipenem (n = 1) or ciprofloxacin (n = 1) in addition to known res
143 d knowledge were assessed through immediate (n = 16111) and 7-month postintervention (n = 146) parent
144 = 61/74; 82%), intravenous immunoglobulins (n = 71/74; 96%), and plasmapheresis (n = 17/74; 23%).
146 termediate-risk patients (2 risk indicators; n = 5,292; 30%) had a 2.2% (95% confidence interval: -0.
147 Overall, we identified more infections (n = 146) in the denosumab group than in the control grou
148 ssion occurred included aromatase inhibitor (n = 36), fulvestrant (n = 21), and tamoxifen (n = 15).
150 iratory conditions (n = 387; 18%), injuries (n = 289; 13%), nonspecific signs and symptoms, e.g., fev
152 olume (n = 1157) and white matter integrity (n = 1089) between depressed individuals and controls in
153 35 of 55; 64%), with bilateral involvement (n = 27 of 55; 47%), tumor masses (n = 27 of 36; 75%), an
156 ), 100 (n = 4), 150 (n = 2), and 200 kBq/kg (n = 4) of (225)Ac-PSMA-617 were evaluated retrospectivel
157 taneous administration of RG-101 at 2 mg/kg (n = 14) or 4 mg/kg (n = 14) or received a placebo (n = 2
158 on of RG-101 at 2 mg/kg (n = 14) or 4 mg/kg (n = 14) or received a placebo (n = 2/dosing group).
160 3), minimally conscious state with language (n = 4) or post-traumatic confusional state (n = 4).
161 minimally conscious state without language (n = 3), minimally conscious state with language (n = 4)
163 , endophthalmitis (n = 1; 2.3%), wound leak (n = 1; 2.3%), and choroidal detachment (n = 2; 4.5%).
164 uently presented with disseminated lymphoma (n = 34 of 55; 62%), and were likely to experience stage
168 on of 52,512 individuals with malformations (n = 196 cases), 305 cases of HF remained (0.88 per 100,0
169 volvement (n = 27 of 55; 47%), tumor masses (n = 27 of 36; 75%), and involvement of the orbit (n = 32
170 subtypes included mantle cell lymphoma (MCL; n = 28), follicular lymphoma (FL; n = 29), diffuse large
172 gned to daily subcutaneous anakinra, 100 mg (n = 25), or placebo (n = 25) for 4 weeks and were follow
174 subgroup of small diameter stents (</=3 mm; n = 95), specificity(82% vs. 62%), positive predictive v
175 ohort included 88 eyes in 3 groups: monthly (n = 19), TREX (n = 30), and control fellow eyes (n = 39)
176 data acquisition rate can be as high as [{n(n + 1)}/2]-fold over conventional EEM spectrometers.
177 hree-fold, partially intermolecular [2+2+n] (n = 1 or 2) cycloaddition with substrates containing thr
178 evealed that 8.6% (n = 13) of "CF negative" (n = 152) and 19.4% (n = 13) of "CF negative" LT + STp (n
181 antagonists (i.e., RhB-(Lys-betaNphe)n-NH2; n = 4-6) are expected to become valuable tools in furthe
183 ificantly higher than those in nondiabetics (n = 39: 0.83 +/- 0.92 and 1.05 +/- 0.99 in 10(8) normal
184 lesi malaria, severe (n = 21) and nonsevere (n = 109) falciparum malaria, and healthy controls (n = 5
185 12 years with severe (n = 47) and nonsevere (n = 99) knowlesi malaria, severe (n = 21) and nonsevere
186 stinguished six secondary signals at NOS1AP (n = 2), ATP1B1 (n = 2), SCN5A (n = 1), and KCNQ1 (n = 1)
187 ns before and after treatment with olaparib (n = 14), a PARP inhibitor, or iniparib (n = 11), which h
188 o severe) for adults aged 60 years or older (n = 16,770) over 3 time periods in the National Health a
190 ecifically target children on their package (n = 747; from 1.9% of foods eligible under Modified-PAHO
196 Here, we show in mice and cancer patients (n = 70) that lung adenocarcinomas increase bone stromal
198 cohort of HIV-1 subtype C-infected patients (n = 168), together with site-directed mutagenesis, revea
200 d plasma was collected from sepsis patients (n = 22 subjects) within 48 hours of admission to the ICU
201 In type 2 diabetes mellitus (T2DM) patients (n = 38), the levels of dG-gx-dC and dG-gx-dA in leukocyt
203 S (n = 10), stable lung transplant patients (n = 18), and healthy aged-matched controls (n = 10).
204 everely injured human blunt trauma patients (n = 472, average injury severity score [ISS] = 20.2) exh
205 Using the DiamondTemp (DT) catheter, pigs (n = 6) underwent discrete atrial ablation in a temperatu
208 neous anakinra, 100 mg (n = 25), or placebo (n = 25) for 4 weeks and were followed for an additional
209 (ages 4-25 years) were treated with placebo (n = 25), Viaskin Peanut 100 mug (VP100; n = 24) or Viask
211 y using a shared healthy control population (n = 36) and in an independent population of white adult
213 f the CHGA promoter in an Indian population (n = 769) yielded nine single-nucleotide polymorphisms (S
215 te (n = 16111) and 7-month postintervention (n = 146) parent surveys in a per protocol analysis of ev
216 ho completed the survey of current practice (n = 46), CONSORT (Consolidated Standards of Reporting Tr
217 mozolomide (n = 3), various herbal products (n = 3), azithromycin (n = 2), and 15 other medications o
222 Forty-five individuals with documented RA (n = 15), spondyloarthropathy (n = 15), and calcium pyrop
228 survivors, using the state cancer registry (n = 5,455) and the general population (n = 16,340) using
230 3), journal editors (n = 9), and regulators (n = 2) (3 participants were included in 2 groups each),
231 gh 2009 who were Washington State residents (n = 1,792; 52% allogeneic and 90% hematologic malignanci
232 dentified heavy smokers that were resistant (n = 65) or susceptible (n = 64) to emphysema with severe
234 is of IFD based on reference method results (n = 117), and specimens with negative fungal culture, bu
235 imaging (fMRI) in a large multisite sample (n = 1,188), we show here that patients with depression c
236 tory analysis using the per-protocol sample (n = 153) failed to show noninferiority of GSH-I (adjuste
238 rs of 12 CNVs associated with schizophrenia (n = 1087) and of carriers of another 41 neurodevelopment
240 (n = 61) was measured in contrast SB series (n = 169, median age 0.94, range 0.32-2.7 years) during 2
241 nonsevere (n = 99) knowlesi malaria, severe (n = 21) and nonsevere (n = 109) falciparum malaria, and
242 ysian patients aged >/=12 years with severe (n = 47) and nonsevere (n = 99) knowlesi malaria, severe
243 d to undergo either standard PM ("no shave", n = 116) or have additional CSM taken ("shave", n = 119)
245 existing data set on eye (n = 625) and skin (n = 684) color from Cape Verde, an island nation off Wes
246 nt set of human colorectal cancer specimens (n = 37) revealed the model recapitulated the spatial lay
248 documented RA (n = 15), spondyloarthropathy (n = 15), and calcium pyrophosphate deposition disease (C
250 ed indicated coma (n = 2), vegetative state (n = 3), minimally conscious state without language (n =
251 16), pharmaceutical industry statisticians (n = 3), journal editors (n = 9), and regulators (n = 2)
252 st-line immunotherapy consisted of steroids (n = 61/74; 82%), intravenous immunoglobulins (n = 71/74;
254 nd 19.4% (n = 13) of "CF negative" LT + STp (n = 67) expressing isolates analyzed harbored CS30.
258 ts (the Manchester Asthma and Allergy Study [n = 30] and the Childhood Origins of Asthma Study [n = 2
259 ] and the Childhood Origins of Asthma Study [n = 28]) was analyzed by using bisulfite sequencing or I
261 = 25) and matched healthy control subjects (n = 23) completed a gambling task featuring a decision b
263 correlated with smartphone data (surrogates: n = 13, rho = 0.56, p < 0.05; n = 13, rho = 0.30, p = 0.
264 infants from the Southampton Women's Survey (n = 696) who were later assessed for asthma, atopic ecze
265 SC (8 surveys; n = 8413) and WRA (4 surveys; n = 4258) from the Biomarkers Reflecting the Inflammatio
266 y).Cross-sectional data for PSC (8 surveys; n = 8413) and WRA (4 surveys; n = 4258) from the Biomark
267 that were resistant (n = 65) or susceptible (n = 64) to emphysema with severe airflow obstruction in
269 d 2 locations (anterior and posterior teeth; n = 12 for each anterior group, n = 13 for each posterio
270 oxicillin/clavulanate (n = 3), temozolomide (n = 3), various herbal products (n = 3), azithromycin (n
271 eived three or fewer prior lines of therapy (n = 23), an objective response rate of 39%, PFS of 6.7 m
273 ere typed to CC398 and a selection of these (n = 38) were further characterised for resistance and vi
274 inical cohorts from tissue microarrays (TMA: n = 208 patients) and whole sections (WS: n = 99 patient
276 ants were randomly assigned to receive tOPV (n = 315) or inactivated polio vaccine (IPV) (n = 299) at
277 ymphocytic leukemia (Richter transformation; n = 7), Waldenstrom macroglobulinemia (n = 4), and margi
279 SDIs during methadone maintenance treatment (n = 23) with a control group (n = 24) in a memory and a
283 2012, and June 25, 2015, to usual care (UC) (n = 75) or UC plus a palliative care intervention (UC +
284 isode of MDD that had remitted by follow-up (n = 4), and offspring with missing baseline MDD data (n
285 ed to distinguish between well vascularized (n = 32) and compromised (n = 27) parathyroid glands duri
286 fferences in subcortical grey matter volume (n = 1157) and white matter integrity (n = 1089) between
287 a multi-ethnic cohort of healthy volunteers (n = 91) and used their tissue to generate induced plurip
288 ebo (n = 25), Viaskin Peanut 100 mug (VP100; n = 24) or Viaskin Peanut 250 mug (VP250; n = 25; DBV Te
292 rial from a separate group of subjects with (n = 11) or without (n = 11) COPD was collected for tissu
293 group of subjects with (n = 11) or without (n = 11) COPD was collected for tissue fibrocyte detectio
294 (61%; 95% CI, 46%-74%) compared with women (n = 660) with normal values (62%; 95% CI, 58%-66%) or af
295 A: n = 208 patients) and whole sections (WS: n = 99 patients), TF was associated with poor prognosis
297 Methods Eligible individuals aged 58 years (n = 1984) living in Turin, Italy, were randomly assigned
298 cond-line ART was 12.9 per 100 person-years (n = 23), and prevalence of VF at censoring was 17.8%.
299 eight and obese Latino children (8-15 years; n = 314) were enrolled between 2001 and 2012 from Los An
300 ncrease was among older patients (>75 years; n = 4441) who experienced an increase from 55.1 per 1000
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