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1 at its peak compared with when it was at its nadir.
2 gen level of 2 ng/mL (2 mug/L) or more above nadir.
3 at recurrence was elevated from postsurgery nadir.
4 rations and the maximum postprandial peak or nadir.
5 re found between left putamen PE/Cr and SaO2 nadir.
6 nly due to a larger decline in the nocturnal nadir.
7 letion among SE reflects the PGC methylation nadir.
8 eperfusion, coinciding with the T cell count nadir.
9 lasma HIV RNA, reading ability, and CD4 cell nadir.
10 pha amplitudes were maximal at low-frequency nadirs.
11 hrombocytopenia; even mild thrombocytopenia (nadir 100 to 149x10(9)/L) was associated with increased
12 microg/dL) and DHEA (baseline: 15.6 +/- 1.3; nadir: 11.2 +/- 1.0; peak: 24.6 +/- 1.6 ng/mL) (P < 0.01
14 027 persons; median age 43 years, median CD4 nadir 178 cells/mm(3), 72% on CART, and 46% with HAND.
15 a Registry (COLD Registry) used the Phoenix (nadir + 2 ng/ml definition) to report 5-year biochemical
17 efined by any of the following: PSA failure (nadir + 2), hormonal intervention, clinical local or dis
18 ith the use of the prostate-specific antigen nadir + 2-ng/mL definition), freedom from distant metast
19 ypoglycemic clamps in which the hypoglycemic nadir, 2.48 +/- 0.06 mmol/l, was reached at a rate of de
20 ycemia was attenuated with SSTR2a treatment (nadir = 3.7 +/- 0.3 vs. 2.7 +/- 0.3 mmol/L in SSTR2a and
21 35.9 degrees C (0.6 degrees C); temperature nadir, 34.3 degrees C (2.8 degrees C); percentage of tim
23 C (2.8 degrees C); percentage of time at the nadir, 4.7% (10.8%); and percentage of time with a tempe
25 d elevated cortisol (baseline: 10.4 +/- 0.4; nadir: 5.9 +/- 0.1; peak: 12.7 +/- 0.9 microg/dL) and DH
26 jects underwent stepped hypoglycemic clamps (nadir 60 mg/dL) with evaluation of counterregulatory hor
27 ed endothelial colony capacity, a CD34+ cell nadir 7 days after AMI, a negative correlation between C
28 -evoked BAT sympathetic nerve activity (SNA, nadirs: -72 and -95%), BAT temperature (Tbat, -0.5 and -
30 11.7 +/- 1.5 vs. 10.9 +/- 1.2, p < .001) and nadir (9.9 +/- 2.1 vs. 8.6 +/- 1.8, p < .001) HGB, and h
32 an reduction of 54.2% from baseline), with a nadir about 6 days after injection and an inverse correl
33 essure from baseline to either 60 minutes or nadir after administration of 23.4% saline was 55.6% (se
34 ics at the time of androgen ablation and the nadir after hormone treatment were strongly correlated w
36 l edema and SRF showed an early reduction to nadir after the initiation of ranibizumab therapy, the e
37 uccess, even when adjusted for CD4(+) T-cell nadir, age at treatment initiation, and other clinical i
39 nsient lower esophageal sphincter relaxation nadir also typically occurred before gastroesophageal ju
40 l therapy, HIV replication, a low CD4 T-cell nadir and a high current CD8 T-cell count are associated
41 s an increase of > or = 25% greater than the nadir and an absolute increase of at least 2 or 5 ng/mL,
42 ctors of response and memory included higher nadir and current CD4 cell percentage, higher CD19 cell
43 n age of 44 years (SD, 10 years), and median nadir and current CD4(+) T-cell counts of 175 cells/micr
44 higher CSF HIV-1 RNA levels included higher nadir and current CD4(+) T-cell counts, a plasma HIV-1 R
45 ent level (CAL) (rho = 0.638, P <0.05), CD4+ nadir and diagnosis (rho = 0.586, P <0.05), and CD4+ nad
47 e mean absorbed dose as higher depletions at nadir and longer delays to recovery were noticed for 3.4
49 diagnosis (rho = 0.418, P <0.005), and CD4+ nadir and moderate probing depth (PD) (rho = 0.424, P <0
50 d missing teeth (rho = 0.380, P <0.05), CD4+ nadir and periodontal diagnosis (rho = 0.418, P <0.005),
51 te models of absolute neutrophil count (ANC) nadir and pharmacokinetic parameters were evaluated.
52 ased cortisol secretion during the circadian nadir and reduced connectivity were both associated with
53 ignificantly increased weight and hemoglobin nadirs and provided enhanced reticulocytosis and faster
54 and measured lowest PSA concentrations (PSA nadir) and those immediately after treatment (PSA end).
56 1 RNA levels >50 copies/mL, a low CD4 T-cell nadir, and a high CD8 T-cell count were independently as
57 ese tissues, the ATP concentration reaches a nadir, and autophagy is induced between 2 and 4 h post-e
59 cortisol levels are consistently low at the nadir, and correspondingly the negative feedback was fou
62 occurrences of a morning peak, early morning nadir, and peak on Mondays in ICD therapies using genera
63 ature, percentage of time at the temperature nadir, and percentage of time with a temperature of less
64 e mutant (mdx-dm) mice to mimic pre-pubertal nadir androgen condition resulted in premature death, ma
65 high cortisol secretion during the circadian nadir are both useful for explaining a significant amoun
67 2), fell further after treatment initiation (nadir at 1 week), and then recovered by 6 months (P = .0
68 decrease, 92.3 x 10(9)/L [38%]), reaching a nadir at 12-24 hours after 24 procedures (50%) and retur
69 had a similar hazard ratio curve but a lower nadir at 131 and 69 mm Hg but age >/= 70 had a higher na
78 rgo diurnal regulation and exhibit peaks and nadirs at similar times and suggest that diurnal modulat
80 ndomized 1:1 either to 4 cycles of leukocyte nadir-based tailored and dose-dense adjuvant epirubicin
81 acks a steep increase in infancy and a later nadir between 1 and 2 y of age, and remains substantiall
82 cebo; weight loss with these drugs reaches a nadir between 20 and 28 weeks; weight loss, averaged 8%-
83 vs liberal: 10.3 [2.1] mmol/L; p = 0.02) and nadir blood glucose (4.4 [1.5] vs 5.5 [1.6] mmol/L; p <
85 of patients with predialysis BP>/=160 mmHg, nadir BP<100 mmHg was most potently associated with mort
86 t associated with outcome, and when added to nadir BP, symptom and intervention criteria did not acce
88 rapidly than autonomic function, reaching a nadir by Day 6, whereas autonomic function reached a nad
89 After insulin, blood and VMH glucose reached nadirs by 30-40 min, and the same rats ate 60% faster an
90 incidence was high even among patients with nadir CD4 cell count >200 cells/microL (140 per 100 000
92 tio [HR] = 1.64; 95% CI, 1.13 to 2.39) and a nadir CD4 count less than 200/microL (HR = 1.67; 95% CI,
95 es while receiving sustained cART and higher nadir CD4 percentage between last vaccine dose and serol
96 Study with a longer ART exposure or a lower nadir CD4 percentage had lower mean LV fractional shorte
100 le 2-long terminal repeat (2-LTR), and lower nadir CD4(+) (P < 0.01) were independent predictors of h
101 odds ratio [AOR] for both, 1.28; P < .001), nadir CD4(+) cell count of <50 cells/muL (AOR, 2.38; P =
102 ed persons with multiple anal HPV types or a nadir CD4(+) cell count of <50 cells/muL have an increas
103 wer serum lipid levels, HIV replication, low nadir CD4(+) cell count, protease inhibitor use, comorbi
105 with stabilized VR had significantly higher nadir CD4(+) count, compared to those with transient PV
107 on, receipt of statin treatment and having a nadir CD4(+) T-cell count of </=100 cell/microL were the
109 troviral therapy-mediated viral suppression, nadir CD4(+) T-cell count, age, sex, and prior cytomegal
110 , sex, past AIDS, HIV transmission category, nadir CD4(+) T-cell count, antiretroviral therapy, HIV R
111 ng for potential confounders, including age, nadir CD4(+) T-cell count, zidovudine use, and comorbid
112 th changes in baseline age and 5% changes in nadir CD4(+) T-cell percentage, HAART was not associated
113 NA levels, while adjusting for peak HIV RNA, nadir CD4(+)count, CD4/CD8 ratio, CMV IgG levels, time f
115 .09 [CI, 1.02 to 1.17]; P = 0.007) and lower nadir CD4+ T-cell count (PR, 0.80 [CI, 0.69 to 0.94]; P
117 between three subgroups based on current and nadir CD4+ T-lymphocyte counts (severely immunosuppresse
118 etween each of these measures and current or nadir CD4+ T-lymphocyte counts, and each measure was com
120 rolled-mean age, 48.9 +/- 10.2 years; median nadir CD4, 270 cells/mL; tertiary educated, 54%; and HIV
122 crosis was associated with white race, lower nadir CD4, prior osteonecrosis, prior fracture, and prio
123 showing a greater than 50% reduction in the nadir chromogranin A level within the 1st year after tre
124 volume abnormalities included CD4 cell count nadir, clinical staging, history of AIDS-defining events
125 showed that MC3-R(-/-) mice exhibit elevated nadir corticosterone as well as a blunted fasting-induce
127 th both doses: -5.8 (95% CI -7.2% to -4.4%) (nadir day 3) compared with -5.5% (95% CI -7.4% to -3.7%)
131 The absolute mean difference between peak-nadir dominant DSA was 68,171 molecules of equivalent so
133 gical outcome at E32, ADC at end of H-I, ADC nadir during H-I and reperfusion-reoxygenation, and area
134 ly rhythm with a zenith at late day time and nadir during the dark in both the Crx(-/-) and the wild
137 ard the Mars Express Spacecraft has detected nadir echoes offset in time-delay from the surface retur
142 cal shape of the J curve was present, with a nadir for cardiovascular events and all-cause mortality
143 The recovery of blood B cells following the nadir from rituximab therapy was characterized by a pred
144 ce intervals, from baseline to 60 minutes or nadir from the six studies from which this information c
146 adjusted model for all-cause mortality: PSA nadir greater than 0.5 ng/mL (adjusted hazard ratio [aHR
148 prostate-specific antigen [PSA] failure, PSA nadir >0.5 ng/mL, PSA doubling time <9 months, and inter
149 The probability of SVR increased with lower nadir Hb for both wild-type and deficient ITPase activit
150 e preoperative hemoglobin (Hb) level and the nadir Hb level during a patient's hospitalization, may b
151 o had a DeltaHb level of less than 50% and a nadir Hb level of 7 g/dL or greater, patients with a Del
153 risk of ischemic complications, even if the nadir Hb level was 7 g/dL or greater (OR, 5.68; 95% CI,
154 with a DeltaHb level of 50% or greater whose nadir Hb level was less than 7 g/dL were at a high risk
155 the DeltaHb concentration following surgery, nadir Hb level, and overall perioperative blood use were
156 Patients were stratified by postoperative nadir hematocrit and the presence of postoperative MI.
157 thout postoperative blood transfusion, lower nadir hematocrit was associated with an increased risk f
159 mice developed a moderate anemia and reached nadir hemoglobin 14 days after injection and partially r
161 on on hospital mortality while adjusting for nadir Hgb level, demographic characteristics, admission
162 time-varying CD4 cell count, CD4 cell count nadir, HIV-1 RNA level, peak HIV-1 RNA level, serum albu
163 aseline eGFR, female gender, lower CD4 count nadir, hypertension, diabetes, and cardiovascular diseas
164 of radiology trainees increased 84.2% from a nadir in 1997 (3080 trainees) to 2011 (5674 trainees) an
165 decrease in PAC use in heart failure, with a nadir in 2009 followed by a subsequent increase (9.1 PAC
167 hypertonia group had significantly less of a nadir in apparent diffusion coefficient (ADC) during H-I
171 ing cortisol levels are extremely low at the nadir in contrast to normal subjects, albeit within the
174 Torpor in hibernating mammals defines the nadir in mammalian metabolic demand and body temperature
179 al principles: failure to achieve the normal nadir in the cortisol diurnal rhythm, loss of sensitivit
181 After serum creatinine reached a stable nadir in the transplant recipients, GFR and its hemodyna
182 had a typical early morning (12 am to 6 am) nadir in therapies, with significantly less than 25% of
184 ing affinity steadily decreases reaching its nadir just upstream of the TSS at the same point where S
186 ow birth weight (LBW) in their late 20s; the nadir LBW for African-American women is under 20 years w
189 increase in HBV DNA, compared with previous nadir levels, and hepatitis flare was defined as a great
191 ined definition of acquired thrombocytopenia-nadir <150x10(9)/L or platelet count drop >or=50%-identi
192 ed on serum CA-125: for patients with CA-125 nadir <or= 10 U/mL, a confirmed value of >or= 20 U/mL se
193 In a multivariate logistic regression model, nadir lymphocyte count, history of depression, and femal
195 with acetaminophen-induced hypotension, the nadir mean arterial pressure was 64 mm Hg (95% CI, 54-74
196 thermia were explored, including temperature nadir, mean intraoperative temperature, percentage of ti
197 nal of CA-125 progression; for patients with nadir more than 10 U/mL, a value >or= 2x nadir that is c
199 story of depression, and female sex, but not nadir neutrophil count, were associated with moderate, s
203 6-1.61), but lower among patients with a CD4 nadir of >/=500 cells/mm(3) (IRR 0.73, 95% CI, .53-1.01)
204 ng OGTT, 18 patients who had a blood glucose nadir of <69 mg/dL had elevated cortisol (baseline: 10.4
206 younger than age 3 years and declining to a nadir of 0.83 after age 10 years (Spearman's rho = 0.60,
208 near Cox proportional hazards model showed a nadir of 136/85 mm Hg (range 130 to 140 mm Hg systolic a
211 drops in deep brain temperature (reaching a nadir of 22.44 +/- 0.74 degrees C), heart rate (from 440
212 en earlier with ctDNA, with a median time to nadir of 37 d (IQR 28-54) compared with a median time to
216 eas the remaining 10 patients with a glucose nadir of 76 +/- 2 mg/dL had no increase in adrenal stero
218 uring hypoglycemia, glucose levels reached a nadir of approximately 2.0 mmol/L, and epinephrine rose
219 on and as glucose levels were declining to a nadir of approximately 50 mg/dl on another occasion.
220 tected before peak viral replication and the nadir of CD4(+) T cell depletion predominantly in lamina
221 was obtained prior to depletion, during the nadir of CD8(+) cell depletion, and after CD8(+) lymphoc
225 mice were exposed to 80 h of (1) either IH (nadir of inspired oxygen 5-6% at 60 cycles h(-1) for 12
226 hypertonic and stillbirth groups had an ADC nadir of less than 0.83 microm(2)/msec (70.3% decrease f
227 se of 1 L for 10 seconds or less, reaching a nadir of less than 90% at least once in 20 subjects and
232 bly, Fbxl3(Afh) extended the duration of the nadir of the PER2-driven bioluminescence rhythm but CK1e
233 an additional R wave (R') or notching in the nadir of the S wave, or >1 R' (fragmentation) in 2 conti
240 regimen): -20.4% (95% CI -26.0% to -14.8%) (nadir on day 5) compared with the standard high (14 d) d
242 d to select men for entry at the time of PSA nadir onto randomized trials evaluating the impact on su
243 ned as >0.5-log(10) increase in HCV RNA from nadir or <2-log decrease at day 5, initiated Peg-IFN/RBV
244 tice criteria to assess whether reported PSA nadir or PSA end concentrations of more than 0.5 ng/mL w
245 as low CD4+ cell counts, whether measured at nadir (OR per 100-cell/muL decrease = 1.53, 95% CI: 1.18
246 ared with 2002 or later), a lower CD4 T-cell nadir (OR, 0.7 [95% CI, .7-.8] per log2 increment), and
247 [Formula: see text]e/[Formula: see text]co2 nadir, or end-exercise [Formula: see text]e/[Formula: se
248 hether insulin action will lock to the peak, nadir, or mean of the normal periodicity of insulin acti
249 pnea-hypopnea index, <30 events per hour) + (nadir oxygen saturation as measured by pulse oximetry >8
252 increased risk of PCSM in the US trial (PSA nadir p=0.0016; PSA end p=0.017) and Australasian trial
254 had a lower mean intraoperative temperature nadir (P = 0.009) and had a greater number of intraopera
255 owed a kinetic impactor and provided--from a nadir perspective--the only images of the debris plume.
256 ) developed new thrombocytopenia, defined as nadir platelet count <150x10(9)/L (referenced lower limi
259 curred at birth, although for some neonates, nadir platelet counts occurred up to 6 days postnatally.
262 rwent inpatient noncardiac surgery and had a nadir postoperative hematocrit between 20% and 30%.
266 ergy to pegaspargase would provide a 48-hour nadir serum asparaginase activity (NSAA) >/= 0.10 IU/mL.
267 500-IU/m(2), adjusted every 3 weeks based on nadir serum asparaginase activity (NSAA) determinations.
271 ing liver parenchyma, and they reached their nadir signal intensity by 10 minutes after the administr
273 systolic BP<120 or 120-159 mmHg, an absolute nadir systolic BP<90 mmHg was most potently associated w
275 operative temperature of 35 degrees C as the nadir temperature most predictive of SSI development.
276 .02) among those who had first-year minimum nadir testosterone </= 0.7, > 0.7 to </= 1.7, and >/= 1.
280 mix (patient demographics, comorbidity, CD4 nadir, time on therapy, and income from VHA administrati
286 of candidate surrogates (ie, PSA end and PSA nadir values >0.5 ng/mL) alone and when assessed in conj
287 or locally advanced prostate cancer with PSA nadir values exceeding 0.5 ng/mL should be considered fo
289 ficantly less likely to have PSA end and PSA nadir values of more than 0.5 ng/mL than were those trea
290 by a rebound thrombocytosis at day 21, with nadir values significantly lower in septic patients.
292 mean duration of high VL burden from peak to nadir was 76 days (95% confidence interval [CI], 58-93 d
293 re 67.5 (95% CI, 41.2 to 104.3) when the CD4 nadir was less than 200/muL for more than 2 years and 24
297 The time to the absolute neutrophil count nadir was shorter for the (90)Y-ibritumomab tiuxetan gro
298 This approach had minimal toxicity with nadir white blood cell counts >2.7 K/microL 2 weeks afte
299 T-cell counts in all patients declined to a nadir within < 1 day and recovered to baseline within a
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